Eptesicus fuscus (big brown bat): 103286217
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Entry
103286217 CDS
T09083
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X2
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00270
Cysteine and methionine metabolism
efus00480
Glutathione metabolism
efus01100
Metabolic pathways
efus01240
Biosynthesis of cofactors
efus04216
Ferroptosis
Module
efus_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
103286217 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
103286217 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
103286217 (GCLC)
Enzymes [BR:
efus01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
103286217 (GCLC)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
103286217
NCBI-ProteinID:
XP_008140277
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Position
10:complement(21590719..21631104)
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AA seq
640 aa
AA seq
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MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKRVQLVLSGEEVVETLQEKGEKTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRQRRKEATSLLKENQAVCTITSFPRLGCPGFTLPECKPTPVEGGASRSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINTPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDVDCRWGVI
SASVDDRTREERGLEPLKNSNYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKGGNAVVDGCGKAQQSMELATEEHEEYALMSIDTIINGKEGVFPGLIPI
LNSYLENMEVDVDTRCSILNYLKLIKKRASGELMTIAKWMREFIANHPDYKQDSVITDQI
NYSLILKCNQIANELCECPELLGPAFKRVKDSGSKTDSSN
NT seq
1923 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagtttctgcacatctaccacgccgtcaaggaccga
cacaaggacgtgctcaagtggggcgatgaggtggaatacatgttggtgtcttttgatcat
gaaaataagagagtccagttggtcctgtctggagaagaagtcgttgagactctacaagaa
aagggggaaaagacaaacccaaaccaccctacactttggagaccagagtatgggagttac
atgattgaagggacgcccggacagccctatggaggaaccatgtccgagttcaacacagtc
gaagacaacatgagacagcgccggaaggaggcaacttctttattaaaagaaaatcaggct
gtttgcacaataacttcatttcccagattaggctgtcctgggttcacgctgccggagtgc
aaacccaccccagtcgaaggaggagcttccaggtccctcttctttcctgatgaagcaata
aacaagcacccccgcttcagcaccctaaccagaaatatccggcataggagaggagaaaaa
gtggtcatcaacacgccaatatttaaagataagaacacaccgtctccgtttatagaaaca
tttcctgaggatgacgaggcggcgaaggcttcaaagcccgatcacatctacatggacgcc
atgggatttgggatgggcaattgctgtcttcaggtaacgttccaagcctgcagcatttct
gaggctagatacctgtatgatcagttggccactatctgcccaattgtcatggctttgagt
gctgcgtctcctttttaccgaggctatgtgtcagacgttgattgtcgctggggcgtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacagt
aactataggattagtaaatcccgatatgattcaatagacagttatctgtccgagtgtggc
gagaaatacaatgacatcgacttgacaatagataaagaaatctacgagcagctgttgcag
gaaggcattgaccacctcctggcccagcatgttgctcatctctttatcagagacccgctg
actctgtttgaagagaaaatacacctggatgatgccaatgagtctgaccattttgagaac
attcagtccacaaattggcagacaatgagatttaagcctcctcctccaaactcagacatt
ggatggagagtggaattccggcccatggaggttcagttaacagacttcgagaactcggcg
tatgtggtgtttgtggtgctgctcacgagagtgatcctttcatacaaattagattttctc
attccactgtcaaaggttgatgaaaacatgaaagtcgcacagaaacgagatgctgtcctg
cagggaatgttctacttcaggaaagatatttgcaaaggtggcaatgctgtggtggacggc
tgtggcaaggcccagcagagcatggagctggccacagaggagcacgaggagtacgccctg
atgagcatagacaccatcatcaatgggaaggaaggcgtgtttcctgggctgatcccgatt
ctcaactcctacctggaaaacatggaagtggatgtggacaccagatgtagtattctaaac
tacctaaagctgattaagaagagagcatctggagaactaatgacaatcgccaaatggatg
agggagtttattgcaaaccatcctgactacaagcaagacagtgtaataaccgatcaaata
aactatagccttattttaaagtgcaaccaaattgcaaatgaattatgtgaatgcccagag
ttacttggaccagcatttaagagagtaaaagacagcggaagtaaaacggactcttccaac
tag
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