Eptesicus fuscus (big brown bat): 103287001
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Entry
103287001 CDS
T09083
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1 isoform X1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus01521
EGFR tyrosine kinase inhibitor resistance
efus01522
Endocrine resistance
efus01524
Platinum drug resistance
efus04010
MAPK signaling pathway
efus04012
ErbB signaling pathway
efus04014
Ras signaling pathway
efus04015
Rap1 signaling pathway
efus04022
cGMP-PKG signaling pathway
efus04024
cAMP signaling pathway
efus04062
Chemokine signaling pathway
efus04066
HIF-1 signaling pathway
efus04068
FoxO signaling pathway
efus04071
Sphingolipid signaling pathway
efus04072
Phospholipase D signaling pathway
efus04114
Oocyte meiosis
efus04140
Autophagy - animal
efus04148
Efferocytosis
efus04150
mTOR signaling pathway
efus04151
PI3K-Akt signaling pathway
efus04210
Apoptosis
efus04218
Cellular senescence
efus04261
Adrenergic signaling in cardiomyocytes
efus04270
Vascular smooth muscle contraction
efus04350
TGF-beta signaling pathway
efus04360
Axon guidance
efus04370
VEGF signaling pathway
efus04371
Apelin signaling pathway
efus04380
Osteoclast differentiation
efus04510
Focal adhesion
efus04520
Adherens junction
efus04540
Gap junction
efus04550
Signaling pathways regulating pluripotency of stem cells
efus04611
Platelet activation
efus04613
Neutrophil extracellular trap formation
efus04620
Toll-like receptor signaling pathway
efus04621
NOD-like receptor signaling pathway
efus04625
C-type lectin receptor signaling pathway
efus04650
Natural killer cell mediated cytotoxicity
efus04657
IL-17 signaling pathway
efus04658
Th1 and Th2 cell differentiation
efus04659
Th17 cell differentiation
efus04660
T cell receptor signaling pathway
efus04662
B cell receptor signaling pathway
efus04664
Fc epsilon RI signaling pathway
efus04666
Fc gamma R-mediated phagocytosis
efus04668
TNF signaling pathway
efus04713
Circadian entrainment
efus04720
Long-term potentiation
efus04722
Neurotrophin signaling pathway
efus04723
Retrograde endocannabinoid signaling
efus04724
Glutamatergic synapse
efus04725
Cholinergic synapse
efus04726
Serotonergic synapse
efus04730
Long-term depression
efus04810
Regulation of actin cytoskeleton
efus04910
Insulin signaling pathway
efus04912
GnRH signaling pathway
efus04914
Progesterone-mediated oocyte maturation
efus04915
Estrogen signaling pathway
efus04916
Melanogenesis
efus04917
Prolactin signaling pathway
efus04919
Thyroid hormone signaling pathway
efus04921
Oxytocin signaling pathway
efus04926
Relaxin signaling pathway
efus04928
Parathyroid hormone synthesis, secretion and action
efus04929
GnRH secretion
efus04930
Type II diabetes mellitus
efus04933
AGE-RAGE signaling pathway in diabetic complications
efus04934
Cushing syndrome
efus04935
Growth hormone synthesis, secretion and action
efus04960
Aldosterone-regulated sodium reabsorption
efus05010
Alzheimer disease
efus05020
Prion disease
efus05022
Pathways of neurodegeneration - multiple diseases
efus05034
Alcoholism
efus05132
Salmonella infection
efus05133
Pertussis
efus05135
Yersinia infection
efus05140
Leishmaniasis
efus05142
Chagas disease
efus05145
Toxoplasmosis
efus05152
Tuberculosis
efus05160
Hepatitis C
efus05161
Hepatitis B
efus05163
Human cytomegalovirus infection
efus05164
Influenza A
efus05165
Human papillomavirus infection
efus05166
Human T-cell leukemia virus 1 infection
efus05167
Kaposi sarcoma-associated herpesvirus infection
efus05170
Human immunodeficiency virus 1 infection
efus05171
Coronavirus disease - COVID-19
efus05200
Pathways in cancer
efus05203
Viral carcinogenesis
efus05205
Proteoglycans in cancer
efus05206
MicroRNAs in cancer
efus05207
Chemical carcinogenesis - receptor activation
efus05208
Chemical carcinogenesis - reactive oxygen species
efus05210
Colorectal cancer
efus05211
Renal cell carcinoma
efus05212
Pancreatic cancer
efus05213
Endometrial cancer
efus05214
Glioma
efus05215
Prostate cancer
efus05216
Thyroid cancer
efus05218
Melanoma
efus05219
Bladder cancer
efus05220
Chronic myeloid leukemia
efus05221
Acute myeloid leukemia
efus05223
Non-small cell lung cancer
efus05224
Breast cancer
efus05225
Hepatocellular carcinoma
efus05226
Gastric cancer
efus05230
Central carbon metabolism in cancer
efus05231
Choline metabolism in cancer
efus05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
efus05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103287001 (MAPK1)
04012 ErbB signaling pathway
103287001 (MAPK1)
04014 Ras signaling pathway
103287001 (MAPK1)
04015 Rap1 signaling pathway
103287001 (MAPK1)
04350 TGF-beta signaling pathway
103287001 (MAPK1)
04370 VEGF signaling pathway
103287001 (MAPK1)
04371 Apelin signaling pathway
103287001 (MAPK1)
04668 TNF signaling pathway
103287001 (MAPK1)
04066 HIF-1 signaling pathway
103287001 (MAPK1)
04068 FoxO signaling pathway
103287001 (MAPK1)
04072 Phospholipase D signaling pathway
103287001 (MAPK1)
04071 Sphingolipid signaling pathway
103287001 (MAPK1)
04024 cAMP signaling pathway
103287001 (MAPK1)
04022 cGMP-PKG signaling pathway
103287001 (MAPK1)
04151 PI3K-Akt signaling pathway
103287001 (MAPK1)
04150 mTOR signaling pathway
103287001 (MAPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103287001 (MAPK1)
04148 Efferocytosis
103287001 (MAPK1)
09143 Cell growth and death
04114 Oocyte meiosis
103287001 (MAPK1)
04210 Apoptosis
103287001 (MAPK1)
04218 Cellular senescence
103287001 (MAPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103287001 (MAPK1)
04520 Adherens junction
103287001 (MAPK1)
04540 Gap junction
103287001 (MAPK1)
04550 Signaling pathways regulating pluripotency of stem cells
103287001 (MAPK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103287001 (MAPK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103287001 (MAPK1)
04613 Neutrophil extracellular trap formation
103287001 (MAPK1)
04620 Toll-like receptor signaling pathway
103287001 (MAPK1)
04621 NOD-like receptor signaling pathway
103287001 (MAPK1)
04625 C-type lectin receptor signaling pathway
103287001 (MAPK1)
04650 Natural killer cell mediated cytotoxicity
103287001 (MAPK1)
04660 T cell receptor signaling pathway
103287001 (MAPK1)
04658 Th1 and Th2 cell differentiation
103287001 (MAPK1)
04659 Th17 cell differentiation
103287001 (MAPK1)
04657 IL-17 signaling pathway
103287001 (MAPK1)
04662 B cell receptor signaling pathway
103287001 (MAPK1)
04664 Fc epsilon RI signaling pathway
103287001 (MAPK1)
04666 Fc gamma R-mediated phagocytosis
103287001 (MAPK1)
04062 Chemokine signaling pathway
103287001 (MAPK1)
09152 Endocrine system
04910 Insulin signaling pathway
103287001 (MAPK1)
04929 GnRH secretion
103287001 (MAPK1)
04912 GnRH signaling pathway
103287001 (MAPK1)
04915 Estrogen signaling pathway
103287001 (MAPK1)
04914 Progesterone-mediated oocyte maturation
103287001 (MAPK1)
04917 Prolactin signaling pathway
103287001 (MAPK1)
04921 Oxytocin signaling pathway
103287001 (MAPK1)
04926 Relaxin signaling pathway
103287001 (MAPK1)
04935 Growth hormone synthesis, secretion and action
103287001 (MAPK1)
04919 Thyroid hormone signaling pathway
103287001 (MAPK1)
04928 Parathyroid hormone synthesis, secretion and action
103287001 (MAPK1)
04916 Melanogenesis
103287001 (MAPK1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
103287001 (MAPK1)
04270 Vascular smooth muscle contraction
103287001 (MAPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
103287001 (MAPK1)
09156 Nervous system
04724 Glutamatergic synapse
103287001 (MAPK1)
04725 Cholinergic synapse
103287001 (MAPK1)
04726 Serotonergic synapse
103287001 (MAPK1)
04720 Long-term potentiation
103287001 (MAPK1)
04730 Long-term depression
103287001 (MAPK1)
04723 Retrograde endocannabinoid signaling
103287001 (MAPK1)
04722 Neurotrophin signaling pathway
103287001 (MAPK1)
09158 Development and regeneration
04360 Axon guidance
103287001 (MAPK1)
04380 Osteoclast differentiation
103287001 (MAPK1)
09159 Environmental adaptation
04713 Circadian entrainment
103287001 (MAPK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103287001 (MAPK1)
05206 MicroRNAs in cancer
103287001 (MAPK1)
05205 Proteoglycans in cancer
103287001 (MAPK1)
05207 Chemical carcinogenesis - receptor activation
103287001 (MAPK1)
05208 Chemical carcinogenesis - reactive oxygen species
103287001 (MAPK1)
05203 Viral carcinogenesis
103287001 (MAPK1)
05230 Central carbon metabolism in cancer
103287001 (MAPK1)
05231 Choline metabolism in cancer
103287001 (MAPK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103287001 (MAPK1)
09162 Cancer: specific types
05210 Colorectal cancer
103287001 (MAPK1)
05212 Pancreatic cancer
103287001 (MAPK1)
05225 Hepatocellular carcinoma
103287001 (MAPK1)
05226 Gastric cancer
103287001 (MAPK1)
05214 Glioma
103287001 (MAPK1)
05216 Thyroid cancer
103287001 (MAPK1)
05221 Acute myeloid leukemia
103287001 (MAPK1)
05220 Chronic myeloid leukemia
103287001 (MAPK1)
05218 Melanoma
103287001 (MAPK1)
05211 Renal cell carcinoma
103287001 (MAPK1)
05219 Bladder cancer
103287001 (MAPK1)
05215 Prostate cancer
103287001 (MAPK1)
05213 Endometrial cancer
103287001 (MAPK1)
05224 Breast cancer
103287001 (MAPK1)
05223 Non-small cell lung cancer
103287001 (MAPK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103287001 (MAPK1)
05170 Human immunodeficiency virus 1 infection
103287001 (MAPK1)
05161 Hepatitis B
103287001 (MAPK1)
05160 Hepatitis C
103287001 (MAPK1)
05171 Coronavirus disease - COVID-19
103287001 (MAPK1)
05164 Influenza A
103287001 (MAPK1)
05163 Human cytomegalovirus infection
103287001 (MAPK1)
05167 Kaposi sarcoma-associated herpesvirus infection
103287001 (MAPK1)
05165 Human papillomavirus infection
103287001 (MAPK1)
09171 Infectious disease: bacterial
05132 Salmonella infection
103287001 (MAPK1)
05135 Yersinia infection
103287001 (MAPK1)
05133 Pertussis
103287001 (MAPK1)
05152 Tuberculosis
103287001 (MAPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
103287001 (MAPK1)
05140 Leishmaniasis
103287001 (MAPK1)
05142 Chagas disease
103287001 (MAPK1)
09164 Neurodegenerative disease
05010 Alzheimer disease
103287001 (MAPK1)
05020 Prion disease
103287001 (MAPK1)
05022 Pathways of neurodegeneration - multiple diseases
103287001 (MAPK1)
09165 Substance dependence
05034 Alcoholism
103287001 (MAPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103287001 (MAPK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103287001 (MAPK1)
04933 AGE-RAGE signaling pathway in diabetic complications
103287001 (MAPK1)
04934 Cushing syndrome
103287001 (MAPK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103287001 (MAPK1)
01524 Platinum drug resistance
103287001 (MAPK1)
01522 Endocrine resistance
103287001 (MAPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
efus01001
]
103287001 (MAPK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
efus03036
]
103287001 (MAPK1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
efus04147
]
103287001 (MAPK1)
Enzymes [BR:
efus01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
103287001 (MAPK1)
Protein kinases [BR:
efus01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
103287001 (MAPK1)
Chromosome and associated proteins [BR:
efus03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
103287001 (MAPK1)
Exosome [BR:
efus04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
103287001 (MAPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
Choline_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
103287001
NCBI-ProteinID:
XP_008140865
LinkDB
All DBs
Position
23:12199031..12285646
Genome browser
AA seq
360 aa
AA seq
DB search
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgac
gtggggccgcgctacaccaacctctcgtacattggcgagggcgcctacggcatggtgtgc
tctgcttatgataatgtcaacaaagttcgagtagctatcaagaaaatcagtccttttgaa
caccagacctactgccagagaaccctgagggagataaaaatcctactgcgcttcagacac
gagaacatcattggaatcaatgatattattcgagcgccaaccatcgagcaaatgaaagat
gtatatatagtacaggacctcatggaaacagatctctacaagctcttgaagacacaacac
ctcagcaacgaccatatctgctattttctttaccagatcctcagagggttaaaatatatc
cattcagctaacgtactgcaccgtgacctcaaaccttccaacctgctgctcaacaccacc
tgtgatctcaagatctgtgattttggcttggcccgcgttgcagatccagaccatgatcac
acagggttcttgacagagtatgtagccacacgttggtacagggctccagagattatgttg
aattccaagggctataccaagtccattgatatttggtctgtaggctgcattctggcagag
atgctctccaacaggcccatcttcccagggaagcattaccttgaccagctgaaccacatt
ctgggtattcttggatccccatcacaggaagacctgaactgcataatcaatctaaaagct
agaaactatttgctttctctcccacacaaaaataaggtgccatggaacaggctgttccca
aatgctgattccaaagctctggatttactggacaaaatgttgaccttcaaccctcacaag
aggattgaagtggaacaagcgctagcccacccgtatctggagcagtattatgacccaagt
gatgagcccatcgctgaagcaccattcaagtttgacatggaattggatgacttgcctaag
gagaagctcaaagaactcatttttgaagagactgctagattccagcctggatatagatct
taa
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integrated database retrieval system