Eptesicus fuscus (big brown bat): 103288414
Help
Entry
103288414 CDS
T09083
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00562
Inositol phosphate metabolism
efus01100
Metabolic pathways
efus04014
Ras signaling pathway
efus04015
Rap1 signaling pathway
efus04020
Calcium signaling pathway
efus04024
cAMP signaling pathway
efus04070
Phosphatidylinositol signaling system
efus04919
Thyroid hormone signaling pathway
efus04933
AGE-RAGE signaling pathway in diabetic complications
efus05205
Proteoglycans in cancer
Module
efus_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
103288414 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
103288414 (PLCE1)
04015 Rap1 signaling pathway
103288414 (PLCE1)
04020 Calcium signaling pathway
103288414 (PLCE1)
04070 Phosphatidylinositol signaling system
103288414 (PLCE1)
04024 cAMP signaling pathway
103288414 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
103288414 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
103288414 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
103288414 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
efus04131
]
103288414 (PLCE1)
Enzymes [BR:
efus01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
103288414 (PLCE1)
Membrane trafficking [BR:
efus04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
103288414 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
103288414 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
103288414
NCBI-ProteinID:
XP_008142307
LinkDB
All DBs
Position
17:38358341..38615352
Genome browser
AA seq
2298 aa
AA seq
DB search
MTSEEMAASDLIPVAQRKVVSSQSAVDESSDKASGVSVPKTHPPGQSGPTSHTISTPNKP
IEETSGSNLPKILSTTRGNIMSDENSNETCWEKDMPDSVENLNMNGNNILENHQRGLPQS
QFYKTCDSVTEEGLHLETGIPSSLERKVFPGIQLELDGPPMGIRPLGNQSAIIETSGAHP
ESDLAVFHFHYELDRRMSDSVCTLSDNLILDDCGNCVSLPDVGREQKKKYMAYTCKLMEL
AKSCDNENKQLQGDHCNALNDEYLCCEGSCRKANVVCSSDSFCREDFTDSPSAETFLSHF
EDFPDNCEDVEDYFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLAAW
SYIDMKRSGSLLPCGRVTGQLSTVPIRQDGSPCLSEAQWYPIYNAVRRGEETEDTIGSLL
HFFTQLPASETAYERINVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGAR
SGLLSTFGGSTGRMMLKERQPGTSVANSSALPSSSAGISKELIDLQPLIQFPEEVASILM
EQEQNIYRRVLPVDYLCFLTQNLGTPECQRSLPCLKASISASILNSQNREHNALEDLVMR
FNEVSSWVTWLILTAGTMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCRVVPFCGVFLKELCEVLDGA
SGLVKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRS
LEAEDEDSPSEGSSSRKNSLKDKARCQFVIGDLLDTENDLFEQPKEWDPHGLEEPQKAFD
HGIELIPWYVLSIRADVHQFLLQGATVIRYDQDTHLSARCFLQLQPDNSTLTWIKPTTAS
PASAKAKLGVLTATSEPGKFPLLGNAGLSGLAEGVLDLFSVKAVYMGHPSIDIHTVCVQN
KLSGMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNMQRNNTLG
IGTAKKKKKILMRGESGEATDDEMATRKAKLHKECRSWSGSDPQDINEQEESEANAITSP
PNPLPSRRAHSLTTAGSPILAAGTSSPIRPVSSPVLSSNKSPSSAWSSSSWHGRIKGGMK
GFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRSGSESAPLYTNLTID
ENTSGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGV
FGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFA
SKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCW
DGDDGMPIIYHGHTLTTKIPFKEVIEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIF
KTVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLAS
MQAQAYNGGNANPPPTNNEEEEDEEDEYDYDYESLSDDNILEDRPESKSCNDKLQFEYNE
EIPKRIKKADNAACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLS
TLNASGSSRGKERKSRKSIFGNNPGRMSPGETASLSKTSGKSSYEGMRQAWEESSSPLSP
TTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNP
LMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDRNCPMYQKFSPLER
DLDNMEPAVYSLTVVSGQNVCPSNSTGSPCIEVDILGMPLDSCHFRTKPIHRNTLNPMWN
EQFFFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSL
FINSRRMEEISSGSSVPASLMFSTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQL
LQQILTTEQDTKPIAADYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSWFPEE
GYVGRIVLKTQQENLEEKSIVQDDREVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTA
QDVIQQTLCKAKYSYSILSNPNPNDYVLLEEVVKDTANKKSSTPKSSQRVLLDQECVFQA
QSKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSPSQVLASESV
QNKEERPVGGSDAMDYRQ
NT seq
6897 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgatctcatacctgtggctcagagaaaagtggtg
tcttctcagtcagctgtagatgaaagtagtgacaaggcctcaggcgtcagtgttccaaag
acacatcctcctgggcagagtgggccgacttctcataccatctcaacaccgaacaaacct
attgaagaaacttctggaagcaacttgcctaagatactctcaacaacaagggggaacatc
atgagtgatgagaacagtaatgaaacgtgctgggagaaagacatgcccgattctgtggag
aaccttaacatgaacggcaacaacatactggaaaaccatcagcgtggtcttcctcagagc
cagttttacaaaacatgtgattctgtcacagaggaaggcctgcatttggaaactggaatc
ccttcttccctggaaagaaaggtgttccctgggattcaactggaactagacggacctccc
atgggcattcgtcccttaggcaatcaatcggcaatcatagagaccagcggggcacaccct
gagagcgatttggcggtatttcactttcattatgaacttgacagaagaatgtcagacagt
gtctgtaccctatcagacaacttgattttggatgattgtggaaactgtgtatcactgcct
gatgtgggtagggagcaaaagaaaaagtatatggcatatacttgcaaactgatggaattg
gcaaaaagctgtgataatgagaacaagcagctacagggtgatcattgtaatgccttgaat
gatgaatacctgtgctgcgaaggttcctgccgaaaggccaacgtggtgtgttctagtgac
agcttttgcagggaggattttactgatagtccatctgccgagacctttctgagccatttt
gaggacttccctgataattgtgaagatgtagaagattattttaaaagtaaaaaggagcga
tccactttgttagtgaggagattttgtaaaaacgacagagaagttaagaagtctgtgtat
actgggacaagggcaattgtgaggactctgccttctggtcacattggactggcagcttgg
agttacattgatatgaagagaagtggaagcctgttgccttgtgggagagtcacgggccag
ctgtcaacagtgccgattaggcaagatgggagcccatgtctgtcagaagcccagtggtat
ccgatctacaatgcagtgagaaggggagaagaaacagaagatacaattggatctcttctc
catttcttcacacagctcccagcctctgagacagcctatgaaaggattaacgttggtccc
tgcttaaagcaatgtgtccgagacaccgtatgtgagtatcgtgccaccctccaacggacc
tccatatctcagtacatcacgggttctctcctagaagcaaccacatctctaggagcaaga
agtgggcttctcagtacttttggaggatccaccggacgaatgatgctgaaagaacgccaa
ccgggcacctctgtggccaattccagtgccctcccttcaagttcagctgggatcagcaag
gaactgattgatctgcagcccctcatccagttccctgaggaagtcgccagcatcctgatg
gagcaggaacagaatatctaccgaagggtcttgccggttgactatctttgcttcttgacc
cagaacttgggcactccagaatgtcagaggtccctgccctgcctcaaagcatccatctcg
gcatcaattcttaactcccagaacagagagcacaatgcccttgaagatcttgtgatgaga
tttaatgaggtgagctcctgggtgacgtggctgatcctcacagccggcaccatggaggag
aagcgggaagtcttctcatatttggtgcatgtggccaaatgctgctggaacatgggcaac
tacaacaccgtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtgg
cagttcatggaccagtctgacctggagaccatgaggagcctgaaggacgccatggctcag
cacgaatcctcctgcgagtacaggaaggtggtgacgcgggcgctgcacatcccgggctgc
agggtggtcccgttctgcggggtgttcctgaaggagctctgcgaagtgctggacggcgcc
tccggcctcgtgaagctctgccccagatacaattcccaggaggaaactctagagtttgta
gctgactacagtggacaagataattttttacaacgcgtgggacaaaatggcttgaagaat
tcagagaaggagtccaccgtcaacagcatctttcagatcatcaggagctgcagccgcagt
ctggaggcggaggacgaggacagccccagtgaggggagcagctctcggaaaaactccctg
aaggacaaagctcgctgccagtttgtaattggagatttgctggatacggaaaatgacctc
tttgagcagcccaaagaatgggaccctcatgggttagaagagccacagaaggcctttgac
cacgggatagagctcatcccatggtacgtgctgtccatccgagctgacgtgcaccagttc
ctgctgcagggggccacggtcatccgctatgaccaggacacgcacctctctgcccgctgc
ttcctccagcttcagcctgacaatagcaccttgacctggataaagcccaccacggcctcc
ccagccagtgcaaaagcaaaacttggtgtgcttactgccacgtccgagcctggcaaattc
ccgttactgggcaacgctggattaagtggcctggcggagggggtcttggatctgttttcc
gtaaaggctgtgtacatggggcaccctagcattgatatacacactgtgtgtgttcagaac
aaactaagtggcatgtttctctcggagactggtgtgacgctgctctatgggcttcagacc
acggacaatagattactgcactttgtggcaccaaagcacacagccaaaatgctcttcagc
ggattgttggaactcactagagctgtgagaaagatgaggaagttccctgaccaaagacag
cagtggctgcggaaacagtacgtcagcctctatcaggaggatggacggtatgaaggccca
actttggctcacgctgtggagttgtttggtggcagacgatggagtactcgaaaccccagc
cctgggacatcagcaaagagtgccgagaagcccaacatgcagaggaacaacaccctgggc
atcggtactgccaagaagaagaagaaaatccttatgaggggtgagagtggagaggcgacc
gacgacgagatggccacccgaaaggccaaactgcacaaagagtgtcgaagctggagtggc
tctgatcctcaggacattaatgagcaagaagagtcagaggcgaatgccatcacaagcccg
cctaaccctctcccttccagaagagcccactctctgaccacggctgggtcccccatcttg
gctgccgggacgtcatctcccatcaggccagtgtcctcccctgtgctgtcttcaaacaag
agcccgtccagtgcctggagcagcagcagctggcacggccgcatcaaaggaggaatgaag
ggctttcagagcttcatggtttccgacagcaacatgagtttcgttgaatttgtggagctg
ttcaaatccttcagtgtaaggagccgcaaggacctgaaggatctcttcgacctctatgcc
gtgccctgcaaccggtcgggctctgagtcggccccgctctacaccaacctaaccattgac
gagaacaccagcggtctccagcctgatctagatttgttgaccagaaatgtctcagatttg
gggctgttcattaagagtaaacagcagctgtcagacaaccagaggcagatctctgacgcc
attgctgctgcaagcatcgtgacgaatggcaccggggtcgagagcacatccctgggcgtg
tttggggtcggcatacttcagctcaatgacttcctagtgaactgccagggagaacactgc
acctatgatgaaatcctcagcatcatccagaagtttgagcctagcattagtatgtgtcat
cagggcctaatgtcatttgaaggatttgcaaggtttctgatggataaagacaactttgct
tcgaaaaatgatgaatcacaggagaacattaaagaattacagctgcccctctcctactat
tacattgaatcttcacacaatacctacctcacaggccatcagctcaaaggagaatcctca
gtagaactctacagccaggtcctcctgcaaggctgtaggagcgtagagttggactgctgg
gacggagatgatgggatgcccatcatttaccatggacatacactgacaaccaagatcccc
ttcaaggaagtgatcgaagccattgatcgcagtgccttcatcaactctgacctgccaatc
atcatatcaattgagaaccactgttcattgcctcagcaacgaaaaatggcagaaattttc
aagactgtgtttggagaaaaactggtggctaaattcttatttgagagtgatttctcagat
gatccaatgcttccttcccctgaccaacttagaaggaaggtgcttctcaaaaataagaag
ctaaaagcccaccagacaccggtggatatcttaaagcaaaaggctcatcagttagcatcc
atgcaagctcaggcttacaatggtgggaatgccaaccccccgcctactaataatgaggag
gaggaagatgaagaggacgagtatgattatgactatgaatccctctctgacgataacatt
ctagaagacagacctgaaagcaaatcgtgtaacgacaagcttcagtttgagtataatgaa
gaaatccccaagaggataaagaaagcagataacgctgcttgcaacaaaggaaaggtgtat
gacatggagttgggagaagaattttatcttcctcagaataaaaaggaaagcagacagatt
gcaccagagctttccgaccttgtcatctattgccaagcagtaaaattcccaggcctgtca
actctaaatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccattttt
ggcaacaatccgggcagaatgagccctggggagacggcatcacttagcaaaacatctgga
aaaagttcctatgaaggaatgcgacaggcctgggaggaatcttcttcccccctcagccca
accacgtccctcagcgctatcattagaactcccaaatgttaccatatctcatcgctgaat
gaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacaccgcc
tgtcagctgctgaggacttacccggctgccacccgcatcgactcctccaaccccaacccc
ctcatgttctggctgcacgggatacagctcgtggcactcaactaccagacagatgatctc
cctttacatttaaacgctgccatgtttgaggccaacggtggctgtggctatgtgctgaaa
ccccccgttctgtgggacaggaactgccccatgtaccagaagttttctcccctggaaaga
gacctggacaacatggagcccgccgtctactctttgactgttgtctctggccagaacgtg
tgcccgagcaacagcacaggaagcccgtgcatcgaggtcgacatcctgggcatgccgctg
gacagctgccacttccgcacgaagcccatccaccggaacactctgaaccccatgtggaac
gagcagtttttcttccgggttcactttgaagacctcatttttcttcgttttgcagttgtg
gaaaacaacagctcggcggtcactgctcagagaatcatcccgctcaaggctctaaagcga
ggatatcgacatcttcagctgcgaaacctccacaatgaagtcttggaaatctctagttta
ttcataaacagcagaaggatggaagaaatctcctccggcagttccgtgccagcctctctg
atgtttagcacagaagaaagaaaatgtctgcagactcacagagtcacggtgcatggggtc
ccaggtccggagcccttcactgttttctctataaatggaggcaccaaggcaaagcagctt
ctccagcaaattctgaccactgaacaagacaccaaacctattgccgcagactactttttg
atggaagaaaaatattttatatctaaagaaaagaatgaatgcagaaaacaaccattccag
agggccattggtcccgaggaggagatcgtgcagattttaagcagctggtttccagaagag
ggctatgttggcaggattgtcttaaaaacccagcaggaaaacctggaagagaaaagcatt
gttcaagatgacagagaggtgatcttgagctcggaggaggagagtttctttgtccaagtg
catgacgtttctccagagcagccgcggaccgtcatcaaagcgccgcgcgtcagcaccgca
caggatgtcattcagcagaccttatgcaaagccaagtactcctacagcatcctgagcaac
cccaacccgaacgactatgtgcttttggaagaggtggtgaaagacacagccaacaagaag
tcttctacccccaagtcctcccagcgggtccttttggatcaggagtgtgtgtttcaagcc
caaagcaagtggaaaggtgcaggaaaattcatccttaagctaaaggagcaggtgcaggca
tcccgagaagacaagagaaaaggcatttcttttgcaagtgaattcaagaagttcaccaag
tcaactaaacagccccgcggactcacatcaccttctcaggtcttggcctcagaaagcgtc
caaaacaaagaggagagacctgtgggtggcagtgacgcgatggactatcgacagtga
DBGET
integrated database retrieval system
