Eptesicus fuscus (big brown bat): 103289372
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Entry
103289372 CDS
T09083
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00190
Oxidative phosphorylation
efus01100
Metabolic pathways
efus04714
Thermogenesis
efus04723
Retrograde endocannabinoid signaling
efus04932
Non-alcoholic fatty liver disease
efus05010
Alzheimer disease
efus05012
Parkinson disease
efus05014
Amyotrophic lateral sclerosis
efus05016
Huntington disease
efus05020
Prion disease
efus05022
Pathways of neurodegeneration - multiple diseases
efus05208
Chemical carcinogenesis - reactive oxygen species
efus05415
Diabetic cardiomyopathy
Module
efus_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
103289372 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
103289372 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
103289372 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
103289372 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
103289372 (NDUFS1)
05012 Parkinson disease
103289372 (NDUFS1)
05014 Amyotrophic lateral sclerosis
103289372 (NDUFS1)
05016 Huntington disease
103289372 (NDUFS1)
05020 Prion disease
103289372 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
103289372 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103289372 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103289372 (NDUFS1)
Enzymes [BR:
efus01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
103289372 (NDUFS1)
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Gene cluster
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
103289372
NCBI-ProteinID:
XP_008143464
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Position
11:81218655..81243818
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AA seq
727 aa
AA seq
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MLRIPVRRALVGLSKSPKEYVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTSWEDALSRVAGMLQTFQGKDVAAIAGGLVDAEALVALKDLLNR
VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSQVDLTYRYDHLGDSPKILQDIASGTHPFSQVLKEAKKPMVVLGSSA
LQRNDGAAILAAVSSIAQKIRMSSGVAGDWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKILRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQASELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctgtgagaagggccttagtaggcctttctaagtctcctaaagaatat
gttcgaacaactgccacagcagcaagcaacttaattgaagtatttgttgacggccaatct
gtcatggtggaaccaggaactactgtcctccaagcttgtgagaaggttggcatgcagatc
cctcgattctgttatcatgaaaggctgtcagttgctggaaactgcaggatgtgccttgtt
gaaatcgagaaagctcctaaggttgtagctgcttgtgccatgccagtaatgaaaggttgg
aatatcttgacaaactcagagaaatctaagaaagccagggaaggtgtgatggagttctta
ttagcaaatcacccattggactgccctatttgtgatcagggaggcgaatgtgatttgcag
gaccagtccatgatgtttggaagtgataggagccggtttttagaggggaaacgtgctgtg
gaggacaagaacattgggccgttggtaaagaccattatgactagatgtatacagtgtact
cgctgcattaggtttgcaagtgagattgcaggagtagatgatttgggaacaacaggcaga
ggaaatgatatgcaagttggcacatacattgaaaagatgtttatgtctgaactgtctggg
aatatcattgatatctgccctgtaggtgccctgacatctaagccctatgccttcactgcc
cggccttgggaaacaagaaagacagaatccattgatgtaatggatgcagttggaagtaat
attgtggtaagcacaagaactggagaggtgatgagaattttgccaagaatgcatgaggac
attaatgaagagtggatctctgataaaaccagatttgcctatgatgggctaaaacgtcaa
agacttaccgagccgatggtcagaaatgaaaaagggcttttaacctatacctcctgggag
gatgcactctctcgtgtagctggaatgttgcagacttttcaaggcaaagatgtagcagca
attgcaggtggcttggtggatgctgaagccctagtagcgctcaaagatttgcttaataga
gtggactctgacaccctgtgcactgaagaggtctttcccactgcaggagctggcacagat
ttgcgttccaattatcttcttaatactacaattgctggtgtggaagaggcagatgttgtc
cttctggttggtacaaatccacgttttgaggcaccactatttaatgctagaattcgaaag
agctggcttcataatgacttaaaagtggcccttataggcagccaagtggatctcacttac
agatatgaccatctgggagattctcccaaaattcttcaagacattgcttcgggtacccat
ccattcagccaggtcctaaaggaagctaaaaaacctatggtggttttaggtagttctgcg
ctccaaagaaatgatggggcagcaattcttgcagctgtttccagcattgctcaaaagatt
cggatgagcagtggtgttgctggtgattggaaagttatgaatatccttcataggattgca
agccaagtagctgctttagaccttggctataaacctggggtggaagcaattcgaaagaac
cctcccaaagtgttatttctcctgggagcagatggaggttgtatcactcgacaggatttg
ccaaaggattgtttcattatttatcaaggacatcatggtgatgttggagctcctattgct
gatgttattctcccaggcgcagcttacacagagaagtctgctacttatgtcaataccgag
ggccgagctcagcagactaaagtagcagtgacacctcctggcttggcgagagaagactgg
aaaattttaagagccctctcggagattgcaggcataactcttccatatgatactctggat
caagtaaggaacagattggaagaagtctctcctaatcttgttcgatatgatgatgttgaa
ggagctaattatttccagcaagcaagtgagctctccaagctagtgaaccagcaactactt
gctgatcctcttgttccacctcagctaacaataaaagacttctatatgacagattcaatt
agcagagcctcacagacaatggccaaatgtgttaaagctgtcacagagggtgcccaggca
gtagaggaaccatccatatgctga
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