Eptesicus fuscus (big brown bat): 103289924
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Entry
103289924 CDS
T09083
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00230
Purine metabolism
efus00670
One carbon pool by folate
efus01100
Metabolic pathways
efus01523
Antifolate resistance
Module
efus_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103289924 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
103289924 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103289924 (GART)
Enzymes [BR:
efus01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
103289924 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
103289924 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
103289924 (GART)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_4
ATP-grasp_3
ATP-grasp_2
Dala_Dala_lig_C
RimK
RoxA-like_Cyt-c
Motif
Other DBs
NCBI-GeneID:
103289924
NCBI-ProteinID:
XP_054569444
LinkDB
All DBs
Position
3:complement(1800305..1823907)
Genome browser
AA seq
1009 aa
AA seq
DB search
MAARVLVVGNGGREHTLAWKLAQSSHVKQVLVAPGNAGTAGSEKISNAAISVGDHRALAQ
FCKDENIEFVVVGPEAPLAAGIVGDLAAAGVRCFGPTAQAARLESSKRFAKEFMDRHGIP
TARWRAFTELEEARSFILSADFPALVVKASGLAAGKGVIVAESREEACRAVQEIMQDKAF
GAAGETIVVEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDRGPNTGGMGACCPAP
QVSQDLLLQIRNAILQRTVDGMQQEGTPYAGVLYAGVMLTRDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCAAPPVWLEHRAAVTVVMASQGYPGSYAKGVEVTGVAEA
QALGLEVFQAGTALKDGKVVTSGGRVLTVTAIRDTLVAALEGAKQGLAAIRFEGAVYRKD
IGGRAIAFLQRPRGLTYKDSGVDIAAGNLLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFRDPLLVSGTDGVGTKLKVAQQCDQHGSIGQDLVAMCVNDVLAQGAEPLFFLDYFSC
GRLDVGTAAAVVAGIAEACRKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAVERDQQLP
RLESIAEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPHGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGRVKAFAHITGGGLLENIPRALPPRCGVELDARAWRVPTIFSWLQREG
RLSDEEMARTFNCGLGAALVVSGDLAEQVLRDVRQHQEEAWLVGRVVARPEGSPRVRVRH
LLDALRLSGPALHNGSVPSPCSAPEKARVAVLISGTGSNLQALIDSTREPSSAAHIAVVV
SNKAAVAGLDRAARAGIPTRVLNHKLYKSRVEFDTAVDQVLEEFSVDIVCLAGFMRILSG
PFVRKWHGRMLNIHPSLLPSFKGANAHEQALDAGVAVTGCTVHFVAEDVDAGRIVLQEAV
PVRRADTVATLSERVKAAEHRIFPAALQLVASGAVRLGEDGRLRWAQEQ
NT seq
3030 nt
NT seq
+upstream
nt +downstream
nt
atggccgcccgagtgcttgtcgttggcaatgggggcagagagcacacgctggcctggaaa
ctggcgcagtcttcccacgtcaaacaggtgttggtcgcccccggaaatgcaggcactgcc
ggctctgagaagatttcaaacgccgccatctccgtcggcgatcacagagccctcgctcag
ttctgcaaagatgagaacattgaattcgtagttgttggaccagaggcacctctggctgcg
gggatcgtcggggacctggcggcggccggcgtgcggtgctttggccccacagcacaagcg
gctcggctagagtccagcaaaaggtttgccaaagagttcatggaccgccatggcatcccg
accgcccggtggagggccttcaccgagctcgaggaggcccgcagcttcatcctgagtgca
gacttccctgctctggtcgtgaaggccagcggcctggccgccgggaagggggtgatcgtg
gcagagagcagagaagaggcctgcagagccgtgcaggagatcatgcaggataaagctttt
ggagcagctggagaaacgattgtcgttgaagaacttcttgaaggagaagaggtttcttgt
ctgtgcttcaccgacgggaggaccgtggcgcccatgccccccgcgcaggaccacaagcgg
ctgctggagggagatcgcggccccaacaccggggggatgggggcctgctgccccgccccg
caggtctctcaggatttgctgctgcagattagaaatgccatccttcagcggacagtggac
ggcatgcagcaggagggcacgccgtacgcaggtgttctctatgcgggtgtgatgctgacc
agggatggcccgaaggttctggagtttaactgccgtttcggggaccccgagtgccaggtg
atcctcccgcttcttaaaagcgatctttacgaagtgattcagtccaccctggacggcctg
ctctgcgcagctccgcctgtttggcttgaacaccgggcggccgtcactgttgtcatggca
agtcagggctatcccggatcctacgccaagggtgtggaggtaacaggggtcgccgaggcc
caggctttggggctggaggtgttccaggcaggcaccgccctgaaagacggcaaagtggtg
accagcggagggcgagtcctcacggtgacggccatccgggacactcttgtcgcagccctc
gaaggggccaagcaaggactggctgctataaggtttgagggcgccgtctacaggaaggac
atcggcggccgcgccatagccttcctccagcggcccaggggcctgacgtacaaggactcg
ggggtagacattgcagccggaaatctgctggtgcagaaaattaagcctctagccaaagcc
acctccagaccaggctgtgatgtggatcttggcggttttgctggtctttttgacttgaaa
gcagcaggtttcagggatcctctcctggtcagtggaacagatggcgttggcacgaagctg
aaggttgcccagcagtgcgaccagcacggttccattggccaggacttggtggcgatgtgc
gtgaacgatgtcctggcccagggggcggagcccctcttcttcctcgactacttttcctgc
gggcgcctcgacgtcggcacggccgcagcagttgtggccggcatcgccgaagcgtgcagg
aaagctgggtgtgccctcctcggaggggaaacagcagaaatgccggacatgtatccccct
ggggagtacgacctggccgggttcgccgtgggggccgtggagcgggaccagcaactccct
cgcctggaaagcatcgctgaaggggatgttgttattggaatagcgtcatctggtctccac
agcaacgggttcagccttgtgaggaagattgtagcgaagtcttcccttcagtactcctcc
ccggcaccccacggctgcggcgaccagaccttgggggacttacttctgactccgaccaga
atctacagccactcgctgttaccggtcctgcgttcgggccgtgtcaaggcctttgcccac
atcaccggcggcgggctgctggagaacatcccccgggccctccctccgaggtgcggggtg
gagttagatgcccgggcctggagggtccccacgatcttctcgtggctgcagcgcgaagga
cgcctctcggacgaggagatggccaggacctttaactgcgggctcggcgctgccctcgtg
gtgtcgggggacctggcggagcaggtgctgagggacgtgcggcagcaccaggaggaggcc
tggctggtcggcagggtggtggcccgccctgaaggttccccccgagtgagagtcaggcac
ctgctggacgccctgcggctgagcgggcccgcgctgcacaacggctccgtgcccagtccc
tgctcggccccggaaaaggccagagtggccgtcctcatctccgggacaggctccaacctg
caggcgctgatagacagcacccgggagccgagcagcgccgcccacatcgccgtggtcgtc
tccaacaaggccgcggtggccgggctggaccgagcggcgcgtgcgggcattcccaccagg
gtgcttaatcacaagttatataaaagccgtgtcgagtttgacacggccgttgaccaggtc
ctcgaggagttctccgtggacatcgtctgcctggcagggttcatgaggatcttgtctggc
cccttcgtcaggaagtggcacgggagaatgctcaacatccacccgtccctgctgccgtcc
ttcaagggcgccaatgcccacgagcaggccctggacgccggcgtcgcggtgacggggtgc
accgtgcacttcgtggctgaagacgtggatgccgggcggattgttttacaggaagctgtg
ccggtgaggagggccgacaccgtggccaccctgtccgagagggtgaaggccgcggagcac
aggatcttccccgccgccctgcagctggtggccagcggcgccgtgcggctgggcgaggac
ggccggctccgctgggcccaggagcagtga
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