Eptesicus fuscus (big brown bat): 103290420
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Entry
103290420 CDS
T09083
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus04010
MAPK signaling pathway
efus04020
Calcium signaling pathway
efus04022
cGMP-PKG signaling pathway
efus04024
cAMP signaling pathway
efus04218
Cellular senescence
efus04260
Cardiac muscle contraction
efus04261
Adrenergic signaling in cardiomyocytes
efus04270
Vascular smooth muscle contraction
efus04530
Tight junction
efus04713
Circadian entrainment
efus04723
Retrograde endocannabinoid signaling
efus04724
Glutamatergic synapse
efus04725
Cholinergic synapse
efus04726
Serotonergic synapse
efus04727
GABAergic synapse
efus04728
Dopaminergic synapse
efus04911
Insulin secretion
efus04912
GnRH signaling pathway
efus04921
Oxytocin signaling pathway
efus04924
Renin secretion
efus04925
Aldosterone synthesis and secretion
efus04927
Cortisol synthesis and secretion
efus04929
GnRH secretion
efus04930
Type II diabetes mellitus
efus04934
Cushing syndrome
efus04935
Growth hormone synthesis, secretion and action
efus04973
Carbohydrate digestion and absorption
efus05010
Alzheimer disease
efus05020
Prion disease
efus05022
Pathways of neurodegeneration - multiple diseases
efus05031
Amphetamine addiction
efus05207
Chemical carcinogenesis - receptor activation
efus05410
Hypertrophic cardiomyopathy
efus05412
Arrhythmogenic right ventricular cardiomyopathy
efus05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103290420 (CACNA1D)
04020 Calcium signaling pathway
103290420 (CACNA1D)
04024 cAMP signaling pathway
103290420 (CACNA1D)
04022 cGMP-PKG signaling pathway
103290420 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
103290420 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
103290420 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
103290420 (CACNA1D)
04929 GnRH secretion
103290420 (CACNA1D)
04912 GnRH signaling pathway
103290420 (CACNA1D)
04921 Oxytocin signaling pathway
103290420 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
103290420 (CACNA1D)
04924 Renin secretion
103290420 (CACNA1D)
04925 Aldosterone synthesis and secretion
103290420 (CACNA1D)
04927 Cortisol synthesis and secretion
103290420 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
103290420 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
103290420 (CACNA1D)
04270 Vascular smooth muscle contraction
103290420 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
103290420 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
103290420 (CACNA1D)
04727 GABAergic synapse
103290420 (CACNA1D)
04725 Cholinergic synapse
103290420 (CACNA1D)
04728 Dopaminergic synapse
103290420 (CACNA1D)
04726 Serotonergic synapse
103290420 (CACNA1D)
04723 Retrograde endocannabinoid signaling
103290420 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
103290420 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
103290420 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
103290420 (CACNA1D)
05020 Prion disease
103290420 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
103290420 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
103290420 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
103290420 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
103290420 (CACNA1D)
05414 Dilated cardiomyopathy
103290420 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103290420 (CACNA1D)
04934 Cushing syndrome
103290420 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
efus04040
]
103290420 (CACNA1D)
Ion channels [BR:
efus04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
103290420 (CACNA1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
103290420
NCBI-ProteinID:
XP_008144551
LinkDB
All DBs
Position
18:41869488..42164851
Genome browser
AA seq
2181 aa
AA seq
DB search
MMMMMMMKKMQHQRQQQADHANEANYARGTRFSLSGEGPTSQPNSSKQTVLSWQAAIEAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYTKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSGGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCIVNGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GEGENQGCWGTLWCWWKRSGAAQAGPSGCRRWGQAISKSKLSRRWRRWNRFSRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQVQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDESQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNHKPEVNQIANSDNKVTIDQYQEEDEDKDPYPP
CDVPVGEEEEEEEEEDEPEVPAGPRPRRISELNMKEKIVPIPEGSAFFILSKTNPIRVGC
HKLINHHVFTNLILVFIMLSSASLAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMT
TFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAK
GLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLF
ILYKDGEVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPELLYKAIDSNGENVG
PIYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYA
LKARPVRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDI
LNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENIPV
PTAPPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAM
LFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGK
LCDPESDYNPGEEYSCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGP
HHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLN
SDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDD
EVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAIS
CDLQDDEPEETKGEEEDVVKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSVPP
ASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPSSTNANLNNANMSKAAPGKQPSIGSLEHV
SENGHDSSHKHDHEPQRRSSRKRARYYETYIRSDSGDEQFPTICREDPEIQGYFRDPRCL
GEPEYFSGEEDYEEDSSPASSRQNYSYYSRHPGSSVDFERPRGYHHPQGFLEDDDSPICY
DSHRSPRRRLLPLTPTSHRRSSFNFECLRRQSSQEEVPPSPTFPHRTALPLHLMQQQVMA
VAGLDSSRAQKYSPSHSTRSWATPPATPPYRDWAPCYTPLIQVEPSEALDQVNGSLPSLH
RSSWYTDEPGISYRTFTPASLTVPSSFHSKNSDKQRSADSLVEAVLISEGLGRYARDPKF
VSATKHEIADACDLTIDEMESAASHLLNGTVHPRANGDVSPDSSRQDYELQDFGPGYSDE
EPDLGREEEDLADEMICITTL
NT seq
6546 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccaggttctctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaactgtcctgtcttggcaggctgcaatcgaggctgcg
agacaggccaaggctgcccaaactatgagcacctccgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacaccaagagcaaaaaacagggtaactcgtctaacagc
cggcctgcccgtgccctcttctgtttatcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattcgaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcttatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtagggttgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcggtaaccactctggtggcaaatcaggaggctttgatgtcaaagccctccgc
gcctttcgagtgttacggccgcttcgactagtatcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctcctccacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaagaggacccagcgccatgtgcgttctca
gggaatgggcgccagtgtatcgttaacggcacggagtgtaggagtggctgggttggcccc
aacggaggcatcaccaacttcgataactttgcctttgctatgctcaccgtgttccagtgc
atcaccatggagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgataatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaagaaagggagaaggcgaaagcccggggc
gatttccagaaactgcgggagaagcagcagctggaagaggacctgaagggctacttggac
tggatcacccaggcggaagacattgatccagagaatgaggaggaaggaggagaggaaagc
aaacgaaataccagcatgccaaccagcgagacggaatctgtgaacacggagaacgtaagt
ggcgaaggcgagaaccaaggctgctggggaactctctggtgctggtggaagagaagcggc
gcggcccaggccgggccctctgggtgccggcggtggggtcaagccatctcaaaatccaag
ctcagccgccgctggcgtcgctggaaccgattcagtcgcagaagatgtagggccgccgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctccgagcactacaaccagcctgactggctgacgcaggtccaagatatcgcgaacaaa
gtcctcctggctctgttcacctgtgagatgctggtgaagatgtacagcctgggtctccag
gcgtatttcgtctccctctttaatcgctttgattgcttcgtggtgtgtgggggcattacg
gagaccatcttggtggagctggaaatcatgtctcccctgggcatctctgtgttccgctgt
gtgcgcctcttacggattttcaaagtgaccaggcactggacatccctgagcaacttggtg
gcgtccctgttaaactccatgaagtccatcgcttcgctgttgctcctgctcttcctcttc
atcatcatcttctccttgctcgggatgcagctgtttggaggcaagtttaatttcgacgag
tcgcagaccaagcggagcacctttgacaatttcccccaggcgcttctcacggtgttccag
attctgacaggtgaagactggaacgctgtgatgtatgacggcatcatggcgtacgggggc
ccgtcatcttcggggatgatcgtctgcatctacttcatcatcctcttcatttgtgggaac
tatattctactgaatgtcttcttggccatcgctgtagacaatttggctgatgctgaaagt
ttgaatactgctcagaaagaggaagctgaagaaaaggaaaggaaaaagatcgccagaaaa
gaaagcctggaaaataaaaagaaccacaaaccggaagtcaatcagatagccaacagtgac
aacaaggtcacaattgatcagtaccaagaagaggatgaggacaaggacccctacccaccc
tgcgatgtgccagtaggggaagaagaagaggaggaggaggaggaggatgaacctgaggtc
ccggctggcccccgtcctcgcagaatctcggagttgaacatgaaagagaaaatcgtcccc
attcctgaagggagcgctttcttcattcttagcaagaccaaccccatccgcgtgggctgc
cacaagctcatcaaccaccacgtcttcaccaacctcatcctcgtcttcatcatgctgagc
agcgcgtccctggccgccgaggaccccatccgcagccactccttcaggaacactatactg
ggttactttgactatgctttcacagccatctttactgttgaaatcctgttaaagatgacg
acctttggagctttcctccacaaaggggccttctgccggaactacttcaacttgctggac
atgctggtcgtcggggtgtcgctggtgtcctttgggatccaatccagtgccatctccgtt
gtgaagattctcagggtcttacgggtcctgaggccgctcagggccatcaacagagcaaaa
ggacttaagcacgtcgttcagtgcgtttttgtggccatccggacgatcggcaacatcatg
atcgtcaccacccttctgcagttcatgtttgcctgcatcggggtccagttgttcaaggga
aagttctatcgctgcacagatgaagccaaaagtaaccccgaggaatgcagggggcttttc
atcctctacaaggatggcgaggttgataaccctgtggtccgtgagaggatctggcaaaac
agcgatttcaattttgacaatgtcctttctgctatgatggcgctgttcacggtctccaca
ttcgagggctggcctgagttgctgtacaaagccattgactcgaacggagagaacgtgggc
ccgatctacaactaccgcgtagagatctccatcttcttcattatctacatcatcatcgtc
gctttcttcatgatgaacatcttcgtgggtttcgtcattgtcacgttccaggagcaggga
gaaaaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgcc
ttgaaagcacgccccgtgcggagatacatccccaaaaacccctaccagtacaagttctgg
tacgtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacaca
ctctgcttggccatgcagcactatgagcagtccaagatgttcaatgacgccatggacatt
ttgaacatggtcttcactggggtgttcactgtcgagatggttttgaaggtcattgcgttt
aagcccaaggggtattttagtgacgcctggaatacgtttgactccctcatcgtaatcggc
agcattatagacgtggccctcagcgaagccgacccaactgaaagtgaaaatatccctgtc
ccaactgctccacctgggaactctgaagagagcaatagaatctccatcacctttttccgt
cttttccgagtgatgcgattggtgaagcttctcagcaggggggaaggcatccggacgctg
ctgtggaccttcattaagtcctttcaggcgctcccgtatgtcgccctgctcatagctatg
ctgttcttcatctacgcggtcatcggcatgcagatgtttgggaaagttgccatgagagac
aacaaccagatcaacaggaacaacaatttccagacctttccccaggcggtgctgctgctg
ttcaggtgtgcgaccggcgaggcctggcaggagatcatgctggcctgcctcccggggaag
ctctgtgaccccgagtcggattacaaccccggggaggagtactcgtgtgggagcaacttc
gccatcgtgtacttcatcagcttttacatgctctgtgcgtttctgatcatcaacctgttt
gtggccgtcatcatggataattttgattatctgacccgggactggtctattctgggacct
caccatttagacgaattcaaaagaatatggtcagaatacgaccccgaggccaaggggagg
atcaagcacctggacgtggtcaccctgctccgccgcatccagccgcccctggggttcggg
aagctgtgcccacacagagtagcctgtaagagactagttgccatgaacatgcctctcaac
agtgatgggacagtcatgtttaatgcaaccctgtttgctttggttcgaacagctcttaaa
atcaagacggaagggaacctggaacaagctaatgaagagctccgagctgtgataaagaaa
atctggaagaaaaccagcatgaagctacttgaccaagttgtccctccagctggtgatgat
gaggtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaattc
aagaaacggaaagaacaaggactggtggggaagtaccctgcgaagaacaccacaattgcc
ctacaggcggggttaaggacactgcacgacatcgggccagagatccggcgggctatatcg
tgtgatctgcaagatgatgagcccgaggaaacgaaaggagaagaagaagatgtagtcaaa
agaaatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagggattcc
cttcagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcagttccacct
gcaagtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccat
cataaccataattccataggaaagcaagttcccagctcaacaaatgccaatctcaataat
gccaatatgtccaaagctgcccccggaaagcagcccagcattgggagccttgagcatgtg
tctgaaaacgggcatgattcctcccacaagcatgaccatgagcctcaaagaaggtccagt
cggaaaagagcccgctattacgaaacttacattaggtccgactcaggagatgagcagttc
cccactatttgccgggaagacccagagatccagggctacttcagggacccccgctgcttg
ggggagcccgagtacttcagcggtgaggaggactacgaggaggacagctcacccgcctcc
agcaggcaaaactacagctactacagccgacacccaggcagcagcgtggatttcgagcgg
ccccgaggctaccaccacccccaaggcttcttggaagacgacgactcgcccatttgctat
gattcccaccgatctccgaggagacgcctactacctctcaccccaacatcgcatcggaga
tcctccttcaacttcgagtgcctgcgccggcagagcagccaggaggaggtcccgccgtcc
cccaccttcccccaccgcacggccctgcctctgcacctgatgcagcaacaggtcatggca
gtcgcaggcctagattcaagcagagcccagaagtactcgccgagccactcgacccggtcg
tgggcgacccctccagcgacccctccgtatcgggactgggcgccgtgctacacccccctg
atccaggtggagccctcggaggccctggaccaggtcaacggcagcctgccctccctgcac
cgcagctcctggtacacggacgagcccggaatctcctaccgcactttcacaccagccagc
ctgactgtccccagcagcttccacagcaaaaacagcgacaagcagaggagcgcggacagc
ttggtggaggcagtcctgatatccgaaggcttaggacggtatgcgagggacccaaaattt
gtgtcggcgacaaaacacgagattgccgatgcctgtgacctaaccatcgacgagatggag
agtgcagccagccacctgcttaatgggaccgtgcacccccgggctaacggggacgtgagc
cccgactcgagccggcaggactacgagctccaggacttcgggccaggttacagcgacgaa
gagccagacctggggagggaggaggaggacctcgcggatgaaatgatatgcatcaccacc
ctgtag
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integrated database retrieval system
