KEGG   Eptesicus fuscus (big brown bat): 103290720
Entry
103290720         CDS       T09083                                 
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X3
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus01521  EGFR tyrosine kinase inhibitor resistance
efus04012  ErbB signaling pathway
efus04062  Chemokine signaling pathway
efus04110  Cell cycle
efus04150  mTOR signaling pathway
efus04151  PI3K-Akt signaling pathway
efus04310  Wnt signaling pathway
efus04340  Hedgehog signaling pathway
efus04360  Axon guidance
efus04390  Hippo signaling pathway
efus04510  Focal adhesion
efus04550  Signaling pathways regulating pluripotency of stem cells
efus04657  IL-17 signaling pathway
efus04660  T cell receptor signaling pathway
efus04662  B cell receptor signaling pathway
efus04722  Neurotrophin signaling pathway
efus04728  Dopaminergic synapse
efus04910  Insulin signaling pathway
efus04916  Melanogenesis
efus04917  Prolactin signaling pathway
efus04919  Thyroid hormone signaling pathway
efus04931  Insulin resistance
efus04932  Non-alcoholic fatty liver disease
efus04934  Cushing syndrome
efus04935  Growth hormone synthesis, secretion and action
efus04936  Alcoholic liver disease
efus05010  Alzheimer disease
efus05020  Prion disease
efus05022  Pathways of neurodegeneration - multiple diseases
efus05135  Yersinia infection
efus05160  Hepatitis C
efus05162  Measles
efus05163  Human cytomegalovirus infection
efus05165  Human papillomavirus infection
efus05167  Kaposi sarcoma-associated herpesvirus infection
efus05200  Pathways in cancer
efus05210  Colorectal cancer
efus05213  Endometrial cancer
efus05215  Prostate cancer
efus05217  Basal cell carcinoma
efus05224  Breast cancer
efus05225  Hepatocellular carcinoma
efus05226  Gastric cancer
efus05415  Diabetic cardiomyopathy
efus05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    103290720 (GSK3B)
   04310 Wnt signaling pathway
    103290720 (GSK3B)
   04340 Hedgehog signaling pathway
    103290720 (GSK3B)
   04390 Hippo signaling pathway
    103290720 (GSK3B)
   04151 PI3K-Akt signaling pathway
    103290720 (GSK3B)
   04150 mTOR signaling pathway
    103290720 (GSK3B)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    103290720 (GSK3B)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103290720 (GSK3B)
   04550 Signaling pathways regulating pluripotency of stem cells
    103290720 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    103290720 (GSK3B)
   04657 IL-17 signaling pathway
    103290720 (GSK3B)
   04662 B cell receptor signaling pathway
    103290720 (GSK3B)
   04062 Chemokine signaling pathway
    103290720 (GSK3B)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103290720 (GSK3B)
   04917 Prolactin signaling pathway
    103290720 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    103290720 (GSK3B)
   04919 Thyroid hormone signaling pathway
    103290720 (GSK3B)
   04916 Melanogenesis
    103290720 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    103290720 (GSK3B)
   04722 Neurotrophin signaling pathway
    103290720 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    103290720 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103290720 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103290720 (GSK3B)
   05225 Hepatocellular carcinoma
    103290720 (GSK3B)
   05226 Gastric cancer
    103290720 (GSK3B)
   05217 Basal cell carcinoma
    103290720 (GSK3B)
   05215 Prostate cancer
    103290720 (GSK3B)
   05213 Endometrial cancer
    103290720 (GSK3B)
   05224 Breast cancer
    103290720 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    103290720 (GSK3B)
   05162 Measles
    103290720 (GSK3B)
   05163 Human cytomegalovirus infection
    103290720 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103290720 (GSK3B)
   05165 Human papillomavirus infection
    103290720 (GSK3B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    103290720 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103290720 (GSK3B)
   05020 Prion disease
    103290720 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    103290720 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103290720 (GSK3B)
   05415 Diabetic cardiomyopathy
    103290720 (GSK3B)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103290720 (GSK3B)
   04932 Non-alcoholic fatty liver disease
    103290720 (GSK3B)
   04931 Insulin resistance
    103290720 (GSK3B)
   04934 Cushing syndrome
    103290720 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103290720 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efus01001]
    103290720 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:efus03036]
    103290720 (GSK3B)
Enzymes [BR:efus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     103290720 (GSK3B)
Protein kinases [BR:efus01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   103290720 (GSK3B)
Chromosome and associated proteins [BR:efus03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    103290720 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 103290720
NCBI-ProteinID: XP_008144863
LinkDB
Position
3:59904183..60085531
AA seq 433 aa
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFNSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANAGDRGQ
TNNAASASASNST
NT seq 1302 nt   +upstreamnt  +downstreamnt
atgtccgggcggcccagaaccacctcctttgcggagagctgcaagccagtgcagcagcct
tcagcgtttggcagcatgaaagttagcagagacaaagatggcagtaaggtgaccacagtg
gtggcaactcctgggcagggtccagacaggccacaagaagtcagctatacagacactaaa
gtgattggaaatgggtcatttggtgtggtatatcaagccaaactttgtgattcaggagaa
ttggttgccatcaagaaagtattgcaagacaagagatttaagaaccgagagctccaaatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactcaagtggt
gagaagaaagatgaggtctatctcaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgcttcctgtgatctatgtcaagttg
tatatgtatcagctgtttcgaagtttagcctatattcattcctttggaatctgccatcgg
gatattaaaccacagaacctcttgttggaccctgatacagctgtattaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagatgta
tggtctgcaggctgtgtgctggctgaactgttgctaggacaaccaatatttccaggggac
agtggtgtggatcaattggtggaaataatcaaggttctggggacaccaacaagggagcaa
attagagaaatgaacccaaactacacagaattcaaatttcctcaaattaaggcacatcct
tggactaaggattcatcaggaacaggacatttcaactcaggagtgcgggttttccgaccc
cgaactccaccagaggcaattgcactgtgtagccgtctgttggagtacacaccaactgcc
cgactgacaccactggaagcttgtgcacattcattttttgatgaattacgggacccaaat
gtcaaactaccaaatgggcgagacacccctgcactcttcaacttcaccactcaagaactg
tccagtaatccacctctagctaccatccttattcctcctcatgctcggattcaagcagct
gcttcaaccccaacaaatgccacagcagcctcagatgctaatgctggagaccgtggacag
accaataacgctgcttctgcatcagcttccaactccacctga

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