Eptesicus fuscus (big brown bat): 103292456
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Entry
103292456 CDS
T09083
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00260
Glycine, serine and threonine metabolism
efus00630
Glyoxylate and dicarboxylate metabolism
efus00670
One carbon pool by folate
efus01100
Metabolic pathways
efus01200
Carbon metabolism
efus01230
Biosynthesis of amino acids
efus01240
Biosynthesis of cofactors
efus01523
Antifolate resistance
efus04981
Folate transport and metabolism
Module
efus_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
103292456 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
103292456 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
103292456 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
103292456 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103292456 (SHMT2)
Enzymes [BR:
efus01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
103292456 (SHMT2)
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
103292456
NCBI-ProteinID:
XP_008146903
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Position
7:complement(52799461..52804716)
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AA seq
504 aa
AA seq
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MLPFSLLWATRPLRRHGQLVRMAMRCQHSEAAQTQAGEASRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDQIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLAVTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGVKSVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACSPMFREYSLQVLKNARA
MADALLDRGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVAFIDEGVKVGLDVKSKTTKLQDFKSFLLNDPETRQ
RLADLRQRVEQFARAFPMPGFDEH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcctttctctttgctctgggccactcggcctctgcggagacatggtcagctggtc
aggatggccatgcggtgccagcacagtgaagcagcccagacccaggctggagaagcaagc
aggggctggacaggccaggagagcctgtcggacagtgaccctgagatgtgggagctgctg
cagagggagaaggacaggcagtgtcgtggcctggaactcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatactacgggggagcagaggtagtggatcaaatcgagctgctgtgtcag
cgccgggccttggaggcctttgacctggatcctgcacagtggggagtcaatgtccagcct
tattcggggtccccagccaatctggctgcctacacagcccttctacagcctcacgaccga
atcatggggctggacctgcccgacggtggccatctcacccatggctatatgtctgatgtc
aagcggatctcagccacatccatcttctttgagtctatgccctataagctgaatccccaa
actggcctcattgactatgaccagctggcagtcactgctcgacttttccgaccacggctc
atcattgctggtaccagtgcctacgctcgcctcattgactacgcccgcatgagggaggtg
tgtgatgaggtcaaggcacacctgctggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccgtcgcctttcaagcatgcggatgttgtcaccacgaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaagggggtgaagtctgtggac
cccaagactggccgggagatcccttatacgtttgaggaccgaatcaactttgcggtgttc
ccgtccctgcaggggggcccccacaaccatgccattgctgccgtggccgtggccctaaag
caggcctgcagccccatgttccgggagtactccctgcaggttctgaagaatgctcgggcc
atggctgatgccctgctagatcgaggctattcgctggtgtctggtggcaccgacaaccac
ctggtgctggtggacctgcggcccaagggcctggatggggctcgggctgagcgggtgctg
gagcttgtgtccatcacagccaacaagaacacctgccccggagaccgaagtgccatcaca
ccagggggccttcggcttggggcaccagccttgacctctcgacagttccgcgaggatgac
ttccggagagttgtggcgtttatagatgaaggggtcaaggttggcttggatgtgaagagc
aagaccaccaaactacaggatttcaaatccttcctgctcaatgacccagaaacaagacaa
cggctggccgacctcaggcagcgggtggagcagtttgccagggctttccccatgcctggc
tttgatgagcactga
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