KEGG   Eptesicus fuscus (big brown bat): 103293119
Entry
103293119         CDS       T09083                                 
Symbol
PRKCA
Name
(RefSeq) protein kinase C alpha type isoform X1
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus01521  EGFR tyrosine kinase inhibitor resistance
efus04010  MAPK signaling pathway
efus04012  ErbB signaling pathway
efus04014  Ras signaling pathway
efus04015  Rap1 signaling pathway
efus04020  Calcium signaling pathway
efus04066  HIF-1 signaling pathway
efus04070  Phosphatidylinositol signaling system
efus04071  Sphingolipid signaling pathway
efus04072  Phospholipase D signaling pathway
efus04082  Neuroactive ligand signaling
efus04150  mTOR signaling pathway
efus04151  PI3K-Akt signaling pathway
efus04261  Adrenergic signaling in cardiomyocytes
efus04270  Vascular smooth muscle contraction
efus04310  Wnt signaling pathway
efus04360  Axon guidance
efus04370  VEGF signaling pathway
efus04510  Focal adhesion
efus04540  Gap junction
efus04613  Neutrophil extracellular trap formation
efus04650  Natural killer cell mediated cytotoxicity
efus04664  Fc epsilon RI signaling pathway
efus04666  Fc gamma R-mediated phagocytosis
efus04670  Leukocyte transendothelial migration
efus04713  Circadian entrainment
efus04720  Long-term potentiation
efus04723  Retrograde endocannabinoid signaling
efus04724  Glutamatergic synapse
efus04725  Cholinergic synapse
efus04726  Serotonergic synapse
efus04727  GABAergic synapse
efus04728  Dopaminergic synapse
efus04730  Long-term depression
efus04750  Inflammatory mediator regulation of TRP channels
efus04911  Insulin secretion
efus04912  GnRH signaling pathway
efus04916  Melanogenesis
efus04918  Thyroid hormone synthesis
efus04919  Thyroid hormone signaling pathway
efus04921  Oxytocin signaling pathway
efus04925  Aldosterone synthesis and secretion
efus04926  Relaxin signaling pathway
efus04928  Parathyroid hormone synthesis, secretion and action
efus04929  GnRH secretion
efus04933  AGE-RAGE signaling pathway in diabetic complications
efus04935  Growth hormone synthesis, secretion and action
efus04960  Aldosterone-regulated sodium reabsorption
efus04961  Endocrine and other factor-regulated calcium reabsorption
efus04970  Salivary secretion
efus04971  Gastric acid secretion
efus04972  Pancreatic secretion
efus05017  Spinocerebellar ataxia
efus05022  Pathways of neurodegeneration - multiple diseases
efus05031  Amphetamine addiction
efus05032  Morphine addiction
efus05143  African trypanosomiasis
efus05146  Amoebiasis
efus05161  Hepatitis B
efus05163  Human cytomegalovirus infection
efus05164  Influenza A
efus05170  Human immunodeficiency virus 1 infection
efus05171  Coronavirus disease - COVID-19
efus05200  Pathways in cancer
efus05205  Proteoglycans in cancer
efus05206  MicroRNAs in cancer
efus05207  Chemical carcinogenesis - receptor activation
efus05214  Glioma
efus05223  Non-small cell lung cancer
efus05225  Hepatocellular carcinoma
efus05231  Choline metabolism in cancer
efus05415  Diabetic cardiomyopathy
efus05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103293119 (PRKCA)
   04012 ErbB signaling pathway
    103293119 (PRKCA)
   04014 Ras signaling pathway
    103293119 (PRKCA)
   04015 Rap1 signaling pathway
    103293119 (PRKCA)
   04310 Wnt signaling pathway
    103293119 (PRKCA)
   04370 VEGF signaling pathway
    103293119 (PRKCA)
   04066 HIF-1 signaling pathway
    103293119 (PRKCA)
   04020 Calcium signaling pathway
    103293119 (PRKCA)
   04070 Phosphatidylinositol signaling system
    103293119 (PRKCA)
   04072 Phospholipase D signaling pathway
    103293119 (PRKCA)
   04071 Sphingolipid signaling pathway
    103293119 (PRKCA)
   04151 PI3K-Akt signaling pathway
    103293119 (PRKCA)
   04150 mTOR signaling pathway
    103293119 (PRKCA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    103293119 (PRKCA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103293119 (PRKCA)
   04540 Gap junction
    103293119 (PRKCA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    103293119 (PRKCA)
   04650 Natural killer cell mediated cytotoxicity
    103293119 (PRKCA)
   04664 Fc epsilon RI signaling pathway
    103293119 (PRKCA)
   04666 Fc gamma R-mediated phagocytosis
    103293119 (PRKCA)
   04670 Leukocyte transendothelial migration
    103293119 (PRKCA)
  09152 Endocrine system
   04911 Insulin secretion
    103293119 (PRKCA)
   04929 GnRH secretion
    103293119 (PRKCA)
   04912 GnRH signaling pathway
    103293119 (PRKCA)
   04921 Oxytocin signaling pathway
    103293119 (PRKCA)
   04926 Relaxin signaling pathway
    103293119 (PRKCA)
   04935 Growth hormone synthesis, secretion and action
    103293119 (PRKCA)
   04918 Thyroid hormone synthesis
    103293119 (PRKCA)
   04919 Thyroid hormone signaling pathway
    103293119 (PRKCA)
   04928 Parathyroid hormone synthesis, secretion and action
    103293119 (PRKCA)
   04916 Melanogenesis
    103293119 (PRKCA)
   04925 Aldosterone synthesis and secretion
    103293119 (PRKCA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103293119 (PRKCA)
   04270 Vascular smooth muscle contraction
    103293119 (PRKCA)
  09154 Digestive system
   04970 Salivary secretion
    103293119 (PRKCA)
   04971 Gastric acid secretion
    103293119 (PRKCA)
   04972 Pancreatic secretion
    103293119 (PRKCA)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103293119 (PRKCA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    103293119 (PRKCA)
  09156 Nervous system
   04724 Glutamatergic synapse
    103293119 (PRKCA)
   04727 GABAergic synapse
    103293119 (PRKCA)
   04725 Cholinergic synapse
    103293119 (PRKCA)
   04728 Dopaminergic synapse
    103293119 (PRKCA)
   04726 Serotonergic synapse
    103293119 (PRKCA)
   04720 Long-term potentiation
    103293119 (PRKCA)
   04730 Long-term depression
    103293119 (PRKCA)
   04723 Retrograde endocannabinoid signaling
    103293119 (PRKCA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103293119 (PRKCA)
  09158 Development and regeneration
   04360 Axon guidance
    103293119 (PRKCA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    103293119 (PRKCA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103293119 (PRKCA)
   05206 MicroRNAs in cancer
    103293119 (PRKCA)
   05205 Proteoglycans in cancer
    103293119 (PRKCA)
   05207 Chemical carcinogenesis - receptor activation
    103293119 (PRKCA)
   05231 Choline metabolism in cancer
    103293119 (PRKCA)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    103293119 (PRKCA)
   05214 Glioma
    103293119 (PRKCA)
   05223 Non-small cell lung cancer
    103293119 (PRKCA)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103293119 (PRKCA)
   05161 Hepatitis B
    103293119 (PRKCA)
   05171 Coronavirus disease - COVID-19
    103293119 (PRKCA)
   05164 Influenza A
    103293119 (PRKCA)
   05163 Human cytomegalovirus infection
    103293119 (PRKCA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103293119 (PRKCA)
   05143 African trypanosomiasis
    103293119 (PRKCA)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    103293119 (PRKCA)
   05022 Pathways of neurodegeneration - multiple diseases
    103293119 (PRKCA)
  09165 Substance dependence
   05031 Amphetamine addiction
    103293119 (PRKCA)
   05032 Morphine addiction
    103293119 (PRKCA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103293119 (PRKCA)
   05415 Diabetic cardiomyopathy
    103293119 (PRKCA)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103293119 (PRKCA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103293119 (PRKCA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efus01001]
    103293119 (PRKCA)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:efus04131]
    103293119 (PRKCA)
Enzymes [BR:efus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     103293119 (PRKCA)
Protein kinases [BR:efus01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   103293119 (PRKCA)
Membrane trafficking [BR:efus04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    103293119 (PRKCA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 ABC1
Other DBs
NCBI-GeneID: 103293119
NCBI-ProteinID: XP_008147623
LinkDB
Position
20:complement(34021811..34307413)
AA seq 671 aa
MADVFSANDSTTPLDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVQDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SIEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNAE
LRQKFEKAKLGPAGNRAYGPSPDRRLSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGT
EELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVN
GGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIAD
FGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGE
DEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRID
WEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQADFEGFSYVNP
QFVHPILQSPV
NT seq 2016 nt   +upstreamnt  +downstreamnt
atggctgacgttttctcggccaacgactccacgacgcctctggacgtggccaaccgcttc
gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacaaggtttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa
tttgttactttttcttgtccgggtgcggacaagggacccgacacggatgacccccggagc
aagcacaagttcaaaatccacacctacgggagccccaccttctgtgaccactgcgggtcg
ctgctgtacgggctcatccaccaggggatgaaatgcgacacctgcgatatgaacgtgcac
aagcagtgcgtgatcaacgtgcccagcctctgtgggatggaccacacggagaagaggggc
cggatctacctgaaggcggaggtcaccgacgaaaagctccacgtcacggtacaagatgcg
aaaaatctaatccccatggatccaaatggactttcagacccatacgtgaagctcaaactc
attcctgatcccaagaatgaaagcaaacaaaaaaccaaaaccatccgctccacactgaac
ccccagtggaacgagtccttcacattcaaattgaaaccttcagataaagaccggcggctg
tccatagaaatctgggactgggaccggacgacaaggaacgacttcatggggtccctttcc
tttggcgtttcggagctgatgaagatgccggccagtggatggtacaagctgctgaaccaa
gaagaaggggagtactacaacgtgcccattccagaaggggacgaagaggggaacgcggag
ctcaggcagaagttcgagaaagccaagcttggccccgctgggaacagagcgtacggcccc
tcgccggacaggagactttccaacaacctggaccgcgtgaagctcaccgacttcaacttc
ctcatggtgctgggaaaggggagttttgggaaggtgatgctggccgacaggaagggcacg
gaagagctctatgccatcaagatcctgaagaaggacgtggtgatccaggacgacgacgtg
gagtgcaccatggtggagaagcgcgtgctggccctgctcgacaagcccccgttcctgacg
cagctgcactcctgcttccagaccgtggatcggctgtacttcgtcatggaatacgtcaac
ggcggggacctcatgtaccacattcagcaagtaggaaaatttaaggagccacaagcagta
ttctatgcagcagagatttccatcggcctgttcttccttcataaaagaggcatcatttac
agggacctgaagttggataacgtcatgctggactcggaggggcacatcaagatcgccgac
ttcgggatgtgcaaggagcacatgatggacggcgtcacgaccagaaccttctgtgggacc
ccagattacatcgccccagagataatcgcttatcagccgtacgggaagtctgtggactgg
tgggcctacggcgtcctgttgtatgaaatgctggctggacagcctccattcgacggcgag
gatgaggacgaactctttcagtctataatggagcacaacgtttcttaccccaaatccttg
tccaaggaggccgtctccatctgcaagggactgatgaccaagcacccggggaagcggctg
ggctgcgggcccgagggcgagcgggacgtgcgcgagcacgccttcttccggaggatcgac
tgggagaagctggagaacagggagatccagccgcccttcaagcccaaagtgtgtggcaaa
ggcgccgaaaacttcgacaagttcttcactcgcgggcagcccgtcctcacgcctcccgac
cagctggtcatcgccaacatcgaccaggctgacttcgaagggttctcgtatgtcaacccc
cagtttgtgcaccccatcttacagagcccagtatga

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