Eptesicus fuscus (big brown bat): 103293136
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Entry
103293136 CDS
T09083
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus04140
Autophagy - animal
efus04141
Protein processing in endoplasmic reticulum
efus04210
Apoptosis
efus04932
Non-alcoholic fatty liver disease
efus05010
Alzheimer disease
efus05012
Parkinson disease
efus05014
Amyotrophic lateral sclerosis
efus05016
Huntington disease
efus05017
Spinocerebellar ataxia
efus05022
Pathways of neurodegeneration - multiple diseases
efus05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
103293136 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103293136 (ERN1)
09143 Cell growth and death
04210 Apoptosis
103293136 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
103293136 (ERN1)
05012 Parkinson disease
103293136 (ERN1)
05014 Amyotrophic lateral sclerosis
103293136 (ERN1)
05016 Huntington disease
103293136 (ERN1)
05017 Spinocerebellar ataxia
103293136 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
103293136 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103293136 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103293136 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
efus01001
]
103293136 (ERN1)
Enzymes [BR:
efus01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103293136 (ERN1)
Protein kinases [BR:
efus01001
]
Serine/threonine kinases: Other
IRE family
103293136 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
103293136
NCBI-ProteinID:
XP_028013191
LinkDB
All DBs
Position
20:complement(32724806..32792740)
Genome browser
AA seq
991 aa
AA seq
DB search
MPARRRPLLLLLLALLLPGSWIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLK
EDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKHNEGLTKLPFTIPELVQASPCRSSDGILY
MGKKQDIWYVIDLLTGEKQQTLSSTFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNA
TYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYGSPVVAFYVWQREGL
RKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASP
SMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKLNPGLKGKNKLNYLRN
YWLLIGHHETPLSASTKMLERFPYNLPKHRENVIPADSEKKSFEDVIHLVDQTSDHAPST
VSPDVEEKFAHAPAKPEAPVDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHR
QFQKELEKIQLLQQQQLPFHAPGDVAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHS
SGSASRAGTGPCLEQDDEDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDSRDVAVK
RILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFA
HLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLA
VGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVVSEGSHPFGKSL
QRQANILLGAYSLDCLQPEKHEDVVARELIEKMISMDPQKRPSAKHVLKHPFFWSLEKQL
QFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRD
LLRAMRNKKHHYRELPVEVRETLGSIPDDFVRYFTSRFPHLLSHTYRAMELCSHERLFQP
YYFHPPPKPQSPVTPDAPEPGRTPSCGPSCD
NT seq
2976 nt
NT seq
+upstream
nt +downstream
nt
atgcccgcccggcggcggccgctgctgctgctgctgttggcgctgctgctgcccggctcc
tggatttttggaagtcccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaacc
ctggatggaagtttgcacgctgtcagcaagaggacaggctcgatcaaatggactttaaaa
gaagatccagttctgcaggttccaacacacgtcgaagagccagccttcctcccggatccc
aacgacggcagcctgtatacacttgggggcaagcataatgaaggcctaacgaaacttccc
tttaccatcccggagttggtacaggcatcgccatgccgaagttcagatgggattctctac
atgggtaaaaagcaggacatttggtatgtcattgaccttctgaccggggagaaacagcag
actttgtcatcgacctttgcagatagcctctgcccttcgacctctcttctgtaccttggg
cgcacagaatacaccatcaccatgtacgacaccaaaacccgagagctccggtggaacgcc
acctacttcgactacgcggcctcgctgcccgaggacgacgtggactacaagatgtcccat
tttgtgtccaatggcgatgggctggtggtgacggtggacagtgaatctggcgacgtcctt
tggatccaaaactatggttcccctgtggtggccttttacgtctggcagcgggaggggctg
cggaaggtgatgcacatcaacgtcgctgtggagaccctgcgctacctgaccttcatgtcc
ggggaggtggggcgcatcaccaagtggaagtaccccttccccaaggagacggaggccaag
agcaagctgacgcccaccctgtatgttgggaaatactctactagcctctacgcctccccc
tcaatggtccacgagggggttgctgttgtgccccgaggcagcacccttcccttgctggaa
ggcccccagactgacggggtcaccattggggacaaaggggagtgtgtgatcacacccagc
acggacctaaagttgaaccctgggctcaaagggaagaacaagctcaactacttgaggaac
tactggcttctgatcgggcaccatgaaacgccgctgtctgcgtctaccaagatgctggag
agattcccctacaatctgcccaaacaccgggaaaatgtgattcctgccgactccgagaaa
aagagctttgaggacgttatccacctggttgaccagacttcagaccatgcgcccagcacc
gtttctccggatgtggaggagaagttcgctcacgcccccgccaagcccgaggcccccgtg
gactctgtgctcaaggacatcgccaccatcatcctgagcaccttcctgctcatcggctgg
gtggccttcatcatcacctaccccctgagcatgcatcagcagcagcagctccagcaccgg
cagttccagaaggaactggagaaaatccagctcctgcaacagcagcagctgcccttccat
gcacccggggacgtggctcaggacgccgagctcctggactcgtccggcctgtactcagag
agctcgggcaccagcagccccagcacgtccccccgagcctccaaccactcgctgcactcc
agcggctctgcctccagggccggcaccggcccctgcctggagcaggacgacgaggatgag
gaaaccagcatggtgatggttgggaaaatttctttctgtcccaaggacgtcctgggccac
ggagcggagggcacaattgtgtaccggggcatgtttgacagccgcgacgtggcggtcaag
aggatcctccccgagtgcttcagtttcgccgaccgcgaggtccagctgctgcgagagtct
gacgagcacccgaacgtgatccgttacttctgcacggagaaggaccggcagttccagtac
atcgccatcgagctgtgcgcggccacgctgcaggagtacgtggagcagaaggacttcgcc
cacctcggcctggagcccatcaccttgctgcagcagaccacctccggcctggcccacctg
cactccctcaacatcgttcacagagacctgaagccccacaacatcctcctctccatgccc
aatgcgcatggcaggatcaaggccatgatctccgacttcggcctctgcaagaagctggca
gtgggcaggcacagcttcagccgccgctcgggggtgcccggcaccgaaggctggatcgcc
ccggagatgctgagtgaggactgcaaggagaaccccacctacacggtggacatcttctct
gcgggctgcgtgttttactacgtggtttctgagggcagccaccctttcggcaagtcccta
cagcgacaggccaacatcctcctgggcgcctacagcctcgactgcttacagcccgagaag
cacgaggacgtcgtcgcccgggagctgatagagaagatgatctccatggacccccagaag
cgcccgtcagcgaagcacgtgctgaagcacccgttcttctggagcctcgagaagcagctc
cagttcttccaggacgtgagtgaccggatagaaaaggagtcactggacggcccgatcgtg
aagcagctggagagaggcgggcgagccgtggtgaagatggactggagggagaacatcacc
gtccccctccagacagatctgcgtaaattcagaacctacaaaggtggctccgtcagagat
ctcctccgagccatgaggaacaagaagcaccactaccgggagctccccgtggaggtgcgg
gagaccctgggctccatccccgacgacttcgtgcgctacttcacgtcgcgcttcccccac
ctcctctcacacacctaccgggccatggagctgtgcagccacgagaggctcttccagccc
tactacttccacccaccccccaagcctcagtcccccgtgactccagacgcccctgagcca
ggccggactccgtcttgtggccccagctgtgactga
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