KEGG   Eptesicus fuscus (big brown bat): 103293309
Entry
103293309         CDS       T09083                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus01521  EGFR tyrosine kinase inhibitor resistance
efus01522  Endocrine resistance
efus04012  ErbB signaling pathway
efus04015  Rap1 signaling pathway
efus04062  Chemokine signaling pathway
efus04081  Hormone signaling
efus04137  Mitophagy - animal
efus04144  Endocytosis
efus04360  Axon guidance
efus04370  VEGF signaling pathway
efus04510  Focal adhesion
efus04520  Adherens junction
efus04530  Tight junction
efus04540  Gap junction
efus04611  Platelet activation
efus04613  Neutrophil extracellular trap formation
efus04625  C-type lectin receptor signaling pathway
efus04727  GABAergic synapse
efus04750  Inflammatory mediator regulation of TRP channels
efus04810  Regulation of actin cytoskeleton
efus04912  GnRH signaling pathway
efus04915  Estrogen signaling pathway
efus04917  Prolactin signaling pathway
efus04919  Thyroid hormone signaling pathway
efus04921  Oxytocin signaling pathway
efus04926  Relaxin signaling pathway
efus05100  Bacterial invasion of epithelial cells
efus05135  Yersinia infection
efus05152  Tuberculosis
efus05161  Hepatitis B
efus05163  Human cytomegalovirus infection
efus05167  Kaposi sarcoma-associated herpesvirus infection
efus05168  Herpes simplex virus 1 infection
efus05203  Viral carcinogenesis
efus05205  Proteoglycans in cancer
efus05207  Chemical carcinogenesis - receptor activation
efus05208  Chemical carcinogenesis - reactive oxygen species
efus05219  Bladder cancer
efus05417  Lipid and atherosclerosis
efus05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    103293309 (SRC)
   04015 Rap1 signaling pathway
    103293309 (SRC)
   04370 VEGF signaling pathway
    103293309 (SRC)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    103293309 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    103293309 (SRC)
   04137 Mitophagy - animal
    103293309 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103293309 (SRC)
   04520 Adherens junction
    103293309 (SRC)
   04530 Tight junction
    103293309 (SRC)
   04540 Gap junction
    103293309 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103293309 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103293309 (SRC)
   04613 Neutrophil extracellular trap formation
    103293309 (SRC)
   04625 C-type lectin receptor signaling pathway
    103293309 (SRC)
   04062 Chemokine signaling pathway
    103293309 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103293309 (SRC)
   04915 Estrogen signaling pathway
    103293309 (SRC)
   04917 Prolactin signaling pathway
    103293309 (SRC)
   04921 Oxytocin signaling pathway
    103293309 (SRC)
   04926 Relaxin signaling pathway
    103293309 (SRC)
   04919 Thyroid hormone signaling pathway
    103293309 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    103293309 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103293309 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    103293309 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103293309 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    103293309 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    103293309 (SRC)
   05203 Viral carcinogenesis
    103293309 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    103293309 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    103293309 (SRC)
   05168 Herpes simplex virus 1 infection
    103293309 (SRC)
   05163 Human cytomegalovirus infection
    103293309 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103293309 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    103293309 (SRC)
   05152 Tuberculosis
    103293309 (SRC)
   05100 Bacterial invasion of epithelial cells
    103293309 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103293309 (SRC)
   05418 Fluid shear stress and atherosclerosis
    103293309 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103293309 (SRC)
   01522 Endocrine resistance
    103293309 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efus01001]
    103293309 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:efus04131]
    103293309 (SRC)
Enzymes [BR:efus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     103293309 (SRC)
Protein kinases [BR:efus01001]
 Non-receptor tyrosine kinases
  SRC family
   103293309 (SRC)
Membrane trafficking [BR:efus04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    103293309 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    103293309 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    103293309 (SRC)
  Macropinocytosis
   Kinases
    103293309 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 DUF7063 SH3_10 ABC1 Haspin_kinase SH3_3
Other DBs
NCBI-GeneID: 103293309
NCBI-ProteinID: XP_008147860
LinkDB
Position
12:37085400..37137838
AA seq 537 aa
MGSNKSKPKDASQRRRSLEPAENAHGGGGGGAFPTSQTPSKPASADGHRGPNTAFSPAAA
EPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEG
DWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRE
SETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADG
LCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKT
LKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGK
YLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEY
TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE
RGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccagcggcgccgcagcctggagcct
gctgagaacgcccatggtggcggcggcgggggtgccttccccacctcacagacccccagc
aagccggcctccgctgatggccaccgtggccccaacacggccttctcccctgccgccgct
gagcccaagctgtttggaggcttcaactcctcggacacggtcacctccccgcagagggcg
gggccgctggctggtggggtgaccacctttgtggccctctacgactatgagtcccggaca
gagactgatctatccttcaagaaaggggagcggctgcagattgtcaacaacacagaggga
gactggtggctggcccactcgctcagcacgggacagacgggctacatccccagcaactac
gtggcaccctccgactccatccaggctgaggagtggtacttcggcaagatcacgagacgg
gagtcagagcggttactgctcaatgcggagaacccgagagggaccttcctagtgagagaa
agcgagaccacgaaaggtgcctactgcctctccgtgtccgacttcgacaacgccaagggc
ctcaacgtgaagcactacaagatccgcaagctggacagcggcggcttctacatcacctct
cgcacccagttcaacagcctccagcagctcgtcgcctactactccaaacatgccgatggc
ctgtgccaccgactcaccactgtgtgccccacgtccaagccacagactcagggcctggcc
aaggacgcgtgggagatcccccgcgagtcactgcggctggaggtcaagctgggccagggc
tgctttggagaggtgtggatggggacctggaacggcaccaccagggtggccatcaaaacc
ctgaagccaggcacgatgtctcccgaggccttcctgcaggaggcccaggtcatgaagaaa
ctgaggcacgagaagctggtgcagctgtacgccgtggtgtctgaggagcccatctacatc
gtcacggagtacatgagcaaggggagtttgctggactttctcaagggggagacgggcaag
tatctgcggctgcctcagctggtggacatggctgctcagatcgcctcaggcatggcgtac
gtggagcggatgaactatgtccaccgggatctccgtgctgccaacatcctggttggagag
aatctcgtgtgcaaagtggctgacttcggcctggctcggctcatcgaagacaacgagtac
acagcccggcaaggtgccaagttccccattaagtggacggctccagaagctgccctctat
ggccggttcaccatcaagtcagacgtgtggtcctttgggatcctgctgacagagctcacg
acaaagggccgggtaccctaccctgggatggtaaaccgggaggtgctggaccaggtggag
cgaggctaccggatgccctgcccacccgagtgtcccgagtccctgcacgacctcatgtgc
cagtgctggcggaaggagcccgaggaacggcccacattcgagtacctgcaggccttcctg
gaggactatttcacgtccactgagccccaataccagcctggagagaacctatag

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