Eptesicus fuscus (big brown bat): 103293749
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Entry
103293749 CDS
T09083
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
103293749 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
efus01002
]
103293749 (BACE1)
Enzymes [BR:
efus01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
103293749 (BACE1)
Peptidases and inhibitors [BR:
efus01002
]
Aspartic peptidases
Family A1: pepsin family
103293749 (BACE1)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
103293749
NCBI-ProteinID:
XP_008148340
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All DBs
Position
13:2898390..2924648
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AA seq
500 aa
AA seq
DB search
MAPALPWLLLWMGSAVLPARCAQPGIRLPLRSGLGGTPLGLRLPRDTEEPEEPGRRGSFV
EMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTY
RDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILG
LAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFSPNQSEVLASVGGSMIIGGID
PSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKV
FEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMSEVTNQSFRITI
LPQQYLRPVEDVATSQDDCYKFAVSQSSTGTVLGAVVMEGFYVVFDRARKRIGFAVSACH
VHDEFRTAAVEGPFVTLDMMDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWR
CLRCLRHQHDDFADDISLLK
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atggccccggcgctgccctggctcctgctgtggatgggctcggcggtgctgcccgcccgc
tgtgcccagcctggcatccggctgcctctgcggagcgggctagggggcacccccctgggc
ctgcgactgccccgggacaccgaggagcccgaggagcccggccggaggggcagcttcgtg
gagatggtggacaacctgaggggcaagtccggtcagggctactatgtggagatgactgtg
ggcagccccccccagacgctcaacatcctggtggacacgggcagcagcaacttcgcagtg
ggggccgcgccccaccctttcctgcatcgctactaccagaggcagctgtccagcacatac
cgggacctccgcaagggcgtgtatgtgccctacacccagggcaagtgggagggggagctg
ggcaccgacctggtgagcatcccccacggccccaatgtcactgtacgtgccaacattgct
gccatcacggagtcagacaagttcttcatcaatggctccaactgggaaggcatcctgggg
ctggcctatgctgagatcgccaggcccgacgactccctggagcctttctttgactcgctg
gtaaagcagacccacgtgcccaacctcttctccctgcagctgtgtggcgccggcttctcc
cccaaccagtcggaagtgctggcctcagtgggaggaagcatgatcattgggggtatcgac
ccctcgctatacacgggcagcctctggtacacacccatccgacgcgagtggtattatgag
gtgatcattgtgcgggtggagatcaatggacaggacctgaaaatggactgcaaggagtac
aactatgataagagcatcgtggacagtggcaccaccaaccttcgtttgcccaagaaagtg
tttgaagctgcagtcaaatccatcaaggcagcctcctcgacggagaagttcccggacggc
ttttggctgggggagcagctggtgtgctggcaggcaggcaccaccccctggaacatcttc
ccggtcatatcgctctacctgatgagcgaggtcaccaaccagtccttccgcatcaccatt
cttccacagcaatacctgcggccagtggaagatgtggccacatcccaagacgactgctac
aagttcgccgtctcccagtcgtccacgggcactgtcctgggagctgtcgtcatggagggc
ttctacgtggtctttgatcgggcgagaaagcggatcggctttgctgtcagtgcttgccat
gtgcacgacgagttccggacggcagcggtggaagggccgtttgtcaccctggacatgatg
gactgtggctacaacatcccacagacagacgagtccaccctcatgaccatagcctacgtc
atggccgccatctgcgccctcttcatgctgccactctgcctgatggtgtgccagtggcgc
tgcctccgctgcctgcgccaccagcacgatgactttgctgacgacatctcgctgctgaag
tga
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