Eptesicus fuscus (big brown bat): 103294241 Help Entry 103294241         CDS       T09083                                  Symbol EGFR Name (RefSeq) epidermal growth factor receptor   KO K04361   epidermal growth factor receptor [EC:2.7.10.1] Organism efus  Eptesicus fuscus (big brown bat) Pathway efus01521   EGFR tyrosine kinase inhibitor resistance efus01522   Endocrine resistance efus03272   Virion - Hepatitis viruses efus04010   MAPK signaling pathway efus04012   ErbB signaling pathway efus04014   Ras signaling pathway efus04015   Rap1 signaling pathway efus04020   Calcium signaling pathway efus04066   HIF-1 signaling pathway efus04068   FoxO signaling pathway efus04072   Phospholipase D signaling pathway efus04144   Endocytosis efus04151   PI3K-Akt signaling pathway efus04510   Focal adhesion efus04520   Adherens junction efus04540   Gap junction efus04630   JAK-STAT signaling pathway efus04810   Regulation of actin cytoskeleton efus04912   GnRH signaling pathway efus04915   Estrogen signaling pathway efus04921   Oxytocin signaling pathway efus04926   Relaxin signaling pathway efus04928   Parathyroid hormone synthesis, secretion and action efus04934   Cushing syndrome efus05160   Hepatitis C efus05163   Human cytomegalovirus infection efus05165   Human papillomavirus infection efus05171   Coronavirus disease - COVID-19 efus05200   Pathways in cancer efus05205   Proteoglycans in cancer efus05206   MicroRNAs in cancer efus05207   Chemical carcinogenesis - receptor activation efus05208   Chemical carcinogenesis - reactive oxygen species efus05210   Colorectal cancer efus05212   Pancreatic cancer efus05213   Endometrial cancer efus05214   Glioma efus05215   Prostate cancer efus05218   Melanoma efus05219   Bladder cancer efus05223   Non-small cell lung cancer efus05224   Breast cancer efus05225   Hepatocellular carcinoma efus05226   Gastric cancer efus05230   Central carbon metabolism in cancer efus05231   Choline metabolism in cancer efus05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:efus00001]  09120 Genetic Information Processing   09125 Information processing in viruses    03272 Virion - Hepatitis viruses     103294241 (EGFR)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103294241 (EGFR)    04012 ErbB signaling pathway     103294241 (EGFR)    04014 Ras signaling pathway     103294241 (EGFR)    04015 Rap1 signaling pathway     103294241 (EGFR)    04630 JAK-STAT signaling pathway     103294241 (EGFR)    04066 HIF-1 signaling pathway     103294241 (EGFR)    04068 FoxO signaling pathway     103294241 (EGFR)    04020 Calcium signaling pathway     103294241 (EGFR)    04072 Phospholipase D signaling pathway     103294241 (EGFR)    04151 PI3K-Akt signaling pathway     103294241 (EGFR)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     103294241 (EGFR)   09144 Cellular community - eukaryotes    04510 Focal adhesion     103294241 (EGFR)    04520 Adherens junction     103294241 (EGFR)    04540 Gap junction     103294241 (EGFR)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103294241 (EGFR)  09150 Organismal Systems   09152 Endocrine system    04912 GnRH signaling pathway     103294241 (EGFR)    04915 Estrogen signaling pathway     103294241 (EGFR)    04921 Oxytocin signaling pathway     103294241 (EGFR)    04926 Relaxin signaling pathway     103294241 (EGFR)    04928 Parathyroid hormone synthesis, secretion and action     103294241 (EGFR)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103294241 (EGFR)    05206 MicroRNAs in cancer     103294241 (EGFR)    05205 Proteoglycans in cancer     103294241 (EGFR)    05207 Chemical carcinogenesis - receptor activation     103294241 (EGFR)    05208 Chemical carcinogenesis - reactive oxygen species     103294241 (EGFR)    05230 Central carbon metabolism in cancer     103294241 (EGFR)    05231 Choline metabolism in cancer     103294241 (EGFR)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     103294241 (EGFR)   09162 Cancer: specific types    05210 Colorectal cancer     103294241 (EGFR)    05212 Pancreatic cancer     103294241 (EGFR)    05225 Hepatocellular carcinoma     103294241 (EGFR)    05226 Gastric cancer     103294241 (EGFR)    05214 Glioma     103294241 (EGFR)    05218 Melanoma     103294241 (EGFR)    05219 Bladder cancer     103294241 (EGFR)    05215 Prostate cancer     103294241 (EGFR)    05213 Endometrial cancer     103294241 (EGFR)    05224 Breast cancer     103294241 (EGFR)    05223 Non-small cell lung cancer     103294241 (EGFR)   09172 Infectious disease: viral    05160 Hepatitis C     103294241 (EGFR)    05171 Coronavirus disease - COVID-19     103294241 (EGFR)    05163 Human cytomegalovirus infection     103294241 (EGFR)    05165 Human papillomavirus infection     103294241 (EGFR)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103294241 (EGFR)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103294241 (EGFR)    01522 Endocrine resistance     103294241 (EGFR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:efus01001]     103294241 (EGFR)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:efus04147]     103294241 (EGFR) Enzymes [BR:efus01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      103294241 (EGFR) Protein kinases [BR:efus01001]  Receptor tyrosine kinases (RTK)   EGFR family [OT]    103294241 (EGFR) Exosome [BR:efus04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    103294241 (EGFR)   Exosomal proteins of pancreatic cancer cells    103294241 (EGFR)   Exosomal proteins of bladder cancer cells    103294241 (EGFR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Kinase-like ABC1 Haspin_kinase Motif Other DBs NCBI-GeneID:  103294241 NCBI-ProteinID:  XP_054582213 LinkDB All DBs Position 14:3018579..3136348 Genome browser AA seq 1207 aa AA seqDB search MRPSRTAGAALLVLLAAQLPARPALEEKRVCQGTNNKLTQLGTFDDHFLSLQRMLNNCEV VLGNLEITYMQRGYDLSFLKTIQEVAGYVLIALNVVEKIPLENLQIIRGNVLFENTHALS VLSNYGGNRTGLQELPMRNLQEILQGAVRFNNNPALCNMETIQWRDIVDSSFLSNMSLDF QSPHGSCRTCDPSCPNGSCWAAGKENCQQLTKTICAQQCSGRCRGKSPSDCCHNQCAAGC TGPRESDCLVCRRFRDGATCKDTCPPLMLYNPTTYQMDVNPDGKYSFGATCVKKCPRNYV VTDHGSCVRACSSDSREVEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIRHFR NCTTISGDLHILPVAFKGDSFTHTPPLDPRELDILKTVKEITGFLLIQAWPENRTDLHAF ENLEIIRGRTKQHGRFSLAVVGLDITSLGLRSLREISDGDVIISNNRNLCYADTIAWRKL FGTTSQKTKIQSNKDGRECKARGRVCHPLCSPEGCWGPAPRDCVACLNVSRERECVEQCH LLEGEPREFVENAECIQCHPECLPQPMNVTCTGRGPDSCVQCAHYIDGPHCVQTCPAGVM GENNTLVWKFADASHVCRLCHPNCTYGCTGPGLEGCPLGPRIPSIAMGIVGGLFLLLMAA LGVGLFLRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSG AFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC LTSTVQLVTQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAAR NVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYG VTVWELMTFGSKPYDGIPASEISTILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKF RELINEFSKMARDPQRYLVIQGDERMNLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQQ GFFHSPATSRTPLLSSLSATSNNSAVTCIDRNGSCPLKEDSFLQRYSSDPTGALTEDNLS DAFLPAPEYMNQSVPKRPAGSVQNPVYHNQPLTPAPGRDPHYQNPPSSAVGNPEYLNTAR PSGVHGAPDGPARWAQNGSHQISLDNPDYQQDFLPKEAKANGLFPGPPAQHADALRVGLP SSESIGA NT seq 3624 nt NT seq  +upstreamnt  +downstreamnt atgcgaccctcccggacggcgggagccgcgctcctggtgctgctggcggcgcagctgccg gcgcgcccggcgctggaggagaagagagtttgccagggcaccaacaacaagctcacccag ctgggcacgttcgacgaccacttcctgagcctgcagcggatgctcaacaactgcgaggtg gtcctggggaacctggagatcacctacatgcagaggggctacgacctgtccttcctgaag accatccaggaggtggccggctacgtcctcatcgccctcaacgtggtggagaagatcccg ctggagaacctgcagatcatccgggggaacgtgctcttcgagaacacccacgccctgtcc gtcctgtccaactacggcggcaacaggacgggcctgcaggagctgcccatgcggaacctg caggaaatcctgcagggcgccgtgcgcttcaacaacaaccccgccctctgcaacatggag accatccagtggcgcgacatcgtggacagcagcttcctgagcaacatgtcgctggacttc cagagcccgcacggcagctgccggacgtgcgacccgagctgccccaacggaagctgctgg gctgcgggcaaggagaactgccagcaactgaccaagaccatctgcgcccagcagtgctcc ggccgctgccggggcaaatccccgagcgactgctgccacaaccagtgtgccgccggctgc accgggccccgcgagagcgactgcctggtctgccgcaggttccgggacggcgccacctgc aaggacacgtgcccgccgctcatgctgtacaaccccaccacctaccagatggacgtcaac ccggacggcaaatacagcttcggcgccacctgcgtgaagaaatgtccccggaactacgtg gtgacggaccacggctcctgcgtgcgggcctgcagctccgacagccgcgaggtggaggaa gacggcgtccgcaagtgcaagaagtgcgaagggccgtgtcgcaaagtgtgtaacgggata gggatcggggagtttaaagacaccctgtccatcaacgccaccaacatcaggcacttccgc aactgcaccaccatcagcggggacctgcacatcctgcccgtggccttcaagggggactcc ttcacccacacgccgcccctggacccgagggagctggacatcctgaagaccgtgaaggag ataacaggcttcctgctgatccaggcctggccggagaaccggacggacctgcacgccttc gagaacctggagatcatccggggccggaccaagcagcacggccgcttctccctcgccgtc gtggggctggacatcacgtccctggggctgcgctccctgagggagatcagtgacggggac gtgatcatctccaacaaccgcaacctgtgctacgcggacaccatcgcctggaggaagctc ttcgggaccacgagccagaaaaccaagatccagagcaacaaggacgggagggagtgcaag gcccgaggccgcgtctgccacccgctgtgctcgcccgagggctgctggggccccgcgccc agggactgcgtggcctgcctgaatgtcagccgcgagcgggagtgcgtggagcagtgccac ctgctggagggcgagcccagggagttcgtggagaacgccgagtgcatccagtgccacccg gagtgcctgccccagcccatgaacgtgacctgcacgggacgcggacccgacagctgcgtg cagtgtgcccactacattgatggccctcactgcgtccagacctgcccggccggggtcatg ggcgagaacaacacgctggtctggaagttcgcggacgccagtcacgtctgccgcctgtgc caccccaactgcacctacggctgtacggggccaggcctcgaaggctgcccgctcgggccc aggatcccgtccatcgccatggggatcgtgggcggcctcttcctgctgctgatggcggcg ctcggggtgggcctgtttctgcgccggcgccacatcgtccgcaagcgcacgctgcgccgg ctgctgcaggagcgggagctcgtggagcccctgacccccagcggggaggcgcccaaccag gccctcctgcggatcctaaaggagaccgagttcaagaagatcaaggtgctgggctccggc gccttcggcaccgtgtacaagggactctggatcccggagggcgagaaggttaaaatcccc gtggccatcaaggaactgcgggaagccacgtctccgaaggccaacaaggaaatcctcgac gaagcctacgtgatggccagcgtggacaaccctcacgtgtgccgcctgctgggcatctgc ctgacctccacggtccagctcgtcacgcagctcatgcccttcggctgcctcctggactac gtgcgcgagcacaaggacaacatcggctcccagtacctgctcaactggtgtgtgcagatc gccaagggcatgaactacctggaggagcggcgcctggtgcaccgggacctggccgccagg aacgtgctggtgaagacgccgcagcacgtcaagatcacggacttcgggctggccaagctg ctgggcgccgaggagaaggagtaccacgcggagggcggcaaggtgcccatcaagtggatg gccctggaatccatcttgcaccggatttacacccaccagagcgacgtctggagctacggg gtcaccgtgtgggagttgatgacctttgggtccaagccctacgacgggatcccggccagt gagatctcgaccatcctggagaaaggggagcgcctcccgcagccgcccatatgcaccatc gacgtctacatgatcatggtcaagtgctggatgatagatgcggacagtcgccccaagttc cgcgagttgatcaacgaattctccaaaatggcccgagacccccagcgctacctcgtcatc cagggcgacgagaggatgaacttgcccagccccacggactccaacttctaccgcgcgctg atggacgaagaggacatggaggacgtggtggacgcggacgagtacctgatcccccagcag ggcttcttccacagccccgccacctcccgcacgcccctgctcagctccctgagtgccacc agcaacaactccgccgtgacttgcatcgatagaaacgggagctgccccctcaaggaagac agcttcctgcagcggtacagctcggaccccaccggcgccctgaccgaggacaacctcagc gacgccttcctgcctgcgccagaatacatgaaccagtcggtccccaagaggccggcgggc tcggtgcagaaccccgtctaccacaaccagcccctgacccccgctcccggccgggacccg cactaccagaacccgcccagcagcgccgtgggcaaccccgagtatctcaacaccgcccgc ccctccggcgtccacggggcccccgacggccctgcccgctgggcgcagaacggcagccac caaatcagcctggacaaccccgactaccagcaggacttcctgcccaaggaggccaaggcc aacggcctcttcccggggcccccggcccagcacgcagatgccctgcgggtggggctgccg agcagcgagtccatcggcgcgtga

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