Eptesicus fuscus (big brown bat): 103295671 Help Entry 103295671         CDS       T09083                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4   KO K10160   toll-like receptor 4 Organism efus  Eptesicus fuscus (big brown bat) Pathway efus04064   NF-kappa B signaling pathway efus04066   HIF-1 signaling pathway efus04145   Phagosome efus04151   PI3K-Akt signaling pathway efus04217   Necroptosis efus04613   Neutrophil extracellular trap formation efus04620   Toll-like receptor signaling pathway efus04621   NOD-like receptor signaling pathway efus04936   Alcoholic liver disease efus05132   Salmonella infection efus05133   Pertussis efus05134   Legionellosis efus05135   Yersinia infection efus05140   Leishmaniasis efus05142   Chagas disease efus05144   Malaria efus05145   Toxoplasmosis efus05146   Amoebiasis efus05152   Tuberculosis efus05161   Hepatitis B efus05162   Measles efus05164   Influenza A efus05170   Human immunodeficiency virus 1 infection efus05171   Coronavirus disease - COVID-19 efus05205   Proteoglycans in cancer efus05235   PD-L1 expression and PD-1 checkpoint pathway in cancer efus05321   Inflammatory bowel disease efus05323   Rheumatoid arthritis efus05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:efus00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     103295671 (TLR4)    04066 HIF-1 signaling pathway     103295671 (TLR4)    04151 PI3K-Akt signaling pathway     103295671 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     103295671 (TLR4)   09143 Cell growth and death    04217 Necroptosis     103295671 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     103295671 (TLR4)    04620 Toll-like receptor signaling pathway     103295671 (TLR4)    04621 NOD-like receptor signaling pathway     103295671 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     103295671 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     103295671 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     103295671 (TLR4)    05161 Hepatitis B     103295671 (TLR4)    05171 Coronavirus disease - COVID-19     103295671 (TLR4)    05164 Influenza A     103295671 (TLR4)    05162 Measles     103295671 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     103295671 (TLR4)    05135 Yersinia infection     103295671 (TLR4)    05133 Pertussis     103295671 (TLR4)    05134 Legionellosis     103295671 (TLR4)    05152 Tuberculosis     103295671 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     103295671 (TLR4)    05144 Malaria     103295671 (TLR4)    05145 Toxoplasmosis     103295671 (TLR4)    05140 Leishmaniasis     103295671 (TLR4)    05142 Chagas disease     103295671 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     103295671 (TLR4)    05321 Inflammatory bowel disease     103295671 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     103295671 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     103295671 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:efus04131]     103295671 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:efus04054]     103295671 (TLR4)    04090 CD molecules [BR:efus04090]     103295671 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:efus00536]     103295671 (TLR4) Membrane trafficking [BR:efus04131]  Endocytosis   Phagocytosis    Toll-like receptors     103295671 (TLR4) Pattern recognition receptors [BR:efus04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    103295671 (TLR4) CD molecules [BR:efus04090]  Proteins   103295671 (TLR4) Glycosaminoglycan binding proteins [BR:efus00536]  Hyaluronan   Cell surface receptors    103295671 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 TIR_2 LRR_9 LRR_6 ThsB_TIR Curto_V2 Motif Other DBs NCBI-GeneID:  103295671 NCBI-ProteinID:  XP_008150338 LinkDB All DBs Position 15:complement(66837440..66848433) Genome browser AA seq 839 aa AA seqDB search MRLTRLAGTLLPAMAFLSCLRPESWDPCVQVVPNVTYQCMELNLYTIPDNIPTTTKNLDL SFNPLRHLGSHSFSNFSELQVLDLSRCEIQKIEDDAYQGLKHLSILILTGNPIQSLAPGA FSGLPSLQTLVAVETNLASLEDFPITHLKSLKELNVAHNLIDSFKLPNYFSNLPNLEHLD LSNNKIRNIYHEDLQVLHQMPSFKLSLDLSLNPLDFIQPGAFEKIKLHELTLRSNFDSAE VMKTFIQGLAGLKIKRLILGEFKNERILVNLDKSALEELCNLTIEEFRIAHFQDFPEDYL GFLNCLADASAISLVSLNIDRLESLPKGFKWQYLNLTNCKFEHFPTLELTFLKQFVFTDN KGITTFTEVNLRNLEFLDLSSNGLSFKSCCSHRDFGTTRLKHLNLSFNSIITMTSNFVGL EQLERLDFQHSTLKQASTFSIFLSLKNLLYLDISYTNIQIVFKGIFDGLISLQVLKMAGN SFQDAFLPNVFRDLTQLTILDLSQCQLEQVSPQAFSSLLRLEVLNMSHNHLLSLDMLPYK NLPLSVLDCSFNRIVAANGQELQHFPSNVTSLHLTQNDFACVCEHMRFLQWVQDHRSILV GAEHMMCKTPLAMQGVPVLSFRNTTCQMNKTVISVSVLSVLVVSVAAVLVYKFYFHLMLL AGCKRYSKGDSTYDAFVIYSSHDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAAN IIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSHAGIIFIVLQKVEKSLLRQ QVELYRLLSRNTYLEWEDSALGRHIFWRRLRKALLDGKPWSPEGTVDAEVSQDETMTSF NT seq 2520 nt NT seq  +upstreamnt  +downstreamnt atgcggctcacccgcctggctgggacgctgctcccagccatggccttcctctcctgcctg agacccgagagctgggacccttgtgtgcaggtggttcctaatgttacttatcagtgcatg gagctgaatctctacacaatccctgataacatccctacaacaaccaagaacctggacctg agctttaaccccctgaggcatttaggcagccacagcttctccaacttctcagaactgcag gtgctggatttatccaggtgtgaaattcagaagattgaagatgatgcatatcaaggccta aaacatctctccatcttgatattgacaggaaaccctatccagagtttagccccaggagcc ttttctggactaccaagtttacagacactggtggctgtggagacaaacctagcctctcta gaggacttccccatcacacatctgaaatccttgaaggagcttaatgtggctcacaatcta atcgattccttcaagttaccgaactatttttctaacctgcctaacctggagcacttggac ctttccaataataagattcgaaatatttaccatgaagacttgcaggttttacatcaaatg ccctcattcaaactctctttagacctgtccctcaaccctttagactttatccaaccaggt gcctttgaaaaaattaagctccatgaactgactttgagaagtaattttgatagtgcagag gtcatgaaaacgtttattcaaggtctggcaggtttaaagatcaaacggctgattctggga gaatttaaaaatgaaaggatcttagtaaacttggacaaatctgccctggaggaactgtgt aatttgaccattgaagaattccggatagcacacttccaagactttccagaggattacctt ggctttttaaattgtttggcagatgcttctgcaatatctctggtgagtctgaatatagac aggctagaaagccttccaaaaggtttcaaatggcaatacttaaacttgactaattgtaaa tttgaacattttcctacattggagcttacctttctcaagcagtttgttttcactgacaac aaaggtattaccacttttactgaagttaatctaagaaaccttgagtttctagatctcagt agcaatggcttgagtttcaagtcttgctgctctcaccgtgattttgggacaacccgactg aaacacttaaatctgagcttcaatagtattattaccatgacttcaaacttcgtgggctta gagcaactagaacgactggatttccagcattccactttgaaacaggccagtactttttca atattcctctcactcaaaaacctcctttaccttgatatctcttacactaacatccagatt gtcttcaagggcatctttgatggcttgatcagcctccaagtcttgaaaatggctggcaat tcctttcaggatgcattccttccaaatgtcttcagagatctgactcagttgactatcctg gacctctctcagtgtcaattggaacaggtgtctccgcaggcattcagctcactccttaga ctcgaggtgctaaatatgagtcacaaccacctcttgtccttggatatgcttccttacaaa aatctccctctctcggttctagactgcagttttaaccgtatagtggccgccaatgggcag gaactacagcattttccaagcaatgtaacttccttacatctgacccagaatgactttgct tgtgtttgtgaacacatgcgtttcctgcagtgggtccaggaccacaggagcatcttggtg ggagctgaacacatgatgtgtaagacacctttagctatgcagggtgtgcctgtgctcagt tttagaaacaccacctgccagatgaacaaaactgtcattagtgtgtccgttctctcagta ctcgtggtatctgtggctgcagttctggtctacaagttctatttccacctgatgcttctg gctggctgcaaaaggtacagcaaaggggacagcacttatgatgcctttgtcatctactcc agccacgatgaggactgggtgaggaatgagttggtaaagaacttggaggagggggtaccc ccctttcagctctgccttcactacagagactttatccctggcgtggccattgctgccaac atcatccaggaaggtttccacaagagcaggaaggtcattgtggtggtgtcccagcacttc atccagagccgatggtgcatctttgaatatgagattgcccagacctggcagttcctgagc agtcacgcgggcatcatcttcatcgtcctgcagaaggtggagaaatccctgctccggcag caggtggagctgtatcgccttctcagcaggaacacttacctagagtgggaggacagtgcc ctgggccggcacatcttctggcgacgactgagaaaagccttgctggatggtaagccatgg agtccagaaggaacagtggatgcagaagtcagtcaggatgaaacaatgacctccttctga

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