Eptesicus fuscus (big brown bat): 103295757
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Entry
103295757 CDS
T09083
Symbol
RAF1
Name
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X1
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus01521
EGFR tyrosine kinase inhibitor resistance
efus01522
Endocrine resistance
efus04010
MAPK signaling pathway
efus04012
ErbB signaling pathway
efus04014
Ras signaling pathway
efus04015
Rap1 signaling pathway
efus04022
cGMP-PKG signaling pathway
efus04024
cAMP signaling pathway
efus04062
Chemokine signaling pathway
efus04068
FoxO signaling pathway
efus04071
Sphingolipid signaling pathway
efus04072
Phospholipase D signaling pathway
efus04140
Autophagy - animal
efus04150
mTOR signaling pathway
efus04151
PI3K-Akt signaling pathway
efus04210
Apoptosis
efus04218
Cellular senescence
efus04270
Vascular smooth muscle contraction
efus04360
Axon guidance
efus04370
VEGF signaling pathway
efus04371
Apelin signaling pathway
efus04510
Focal adhesion
efus04540
Gap junction
efus04550
Signaling pathways regulating pluripotency of stem cells
efus04613
Neutrophil extracellular trap formation
efus04625
C-type lectin receptor signaling pathway
efus04630
JAK-STAT signaling pathway
efus04650
Natural killer cell mediated cytotoxicity
efus04660
T cell receptor signaling pathway
efus04662
B cell receptor signaling pathway
efus04664
Fc epsilon RI signaling pathway
efus04666
Fc gamma R-mediated phagocytosis
efus04720
Long-term potentiation
efus04722
Neurotrophin signaling pathway
efus04726
Serotonergic synapse
efus04730
Long-term depression
efus04810
Regulation of actin cytoskeleton
efus04910
Insulin signaling pathway
efus04912
GnRH signaling pathway
efus04914
Progesterone-mediated oocyte maturation
efus04915
Estrogen signaling pathway
efus04916
Melanogenesis
efus04917
Prolactin signaling pathway
efus04919
Thyroid hormone signaling pathway
efus04921
Oxytocin signaling pathway
efus04926
Relaxin signaling pathway
efus04928
Parathyroid hormone synthesis, secretion and action
efus04929
GnRH secretion
efus04935
Growth hormone synthesis, secretion and action
efus05010
Alzheimer disease
efus05022
Pathways of neurodegeneration - multiple diseases
efus05034
Alcoholism
efus05132
Salmonella infection
efus05152
Tuberculosis
efus05160
Hepatitis C
efus05161
Hepatitis B
efus05163
Human cytomegalovirus infection
efus05164
Influenza A
efus05165
Human papillomavirus infection
efus05167
Kaposi sarcoma-associated herpesvirus infection
efus05170
Human immunodeficiency virus 1 infection
efus05200
Pathways in cancer
efus05205
Proteoglycans in cancer
efus05206
MicroRNAs in cancer
efus05207
Chemical carcinogenesis - receptor activation
efus05208
Chemical carcinogenesis - reactive oxygen species
efus05210
Colorectal cancer
efus05211
Renal cell carcinoma
efus05212
Pancreatic cancer
efus05213
Endometrial cancer
efus05214
Glioma
efus05215
Prostate cancer
efus05218
Melanoma
efus05219
Bladder cancer
efus05220
Chronic myeloid leukemia
efus05221
Acute myeloid leukemia
efus05223
Non-small cell lung cancer
efus05224
Breast cancer
efus05225
Hepatocellular carcinoma
efus05226
Gastric cancer
efus05230
Central carbon metabolism in cancer
efus05231
Choline metabolism in cancer
efus05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103295757 (RAF1)
04012 ErbB signaling pathway
103295757 (RAF1)
04014 Ras signaling pathway
103295757 (RAF1)
04015 Rap1 signaling pathway
103295757 (RAF1)
04370 VEGF signaling pathway
103295757 (RAF1)
04371 Apelin signaling pathway
103295757 (RAF1)
04630 JAK-STAT signaling pathway
103295757 (RAF1)
04068 FoxO signaling pathway
103295757 (RAF1)
04072 Phospholipase D signaling pathway
103295757 (RAF1)
04071 Sphingolipid signaling pathway
103295757 (RAF1)
04024 cAMP signaling pathway
103295757 (RAF1)
04022 cGMP-PKG signaling pathway
103295757 (RAF1)
04151 PI3K-Akt signaling pathway
103295757 (RAF1)
04150 mTOR signaling pathway
103295757 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103295757 (RAF1)
09143 Cell growth and death
04210 Apoptosis
103295757 (RAF1)
04218 Cellular senescence
103295757 (RAF1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103295757 (RAF1)
04540 Gap junction
103295757 (RAF1)
04550 Signaling pathways regulating pluripotency of stem cells
103295757 (RAF1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103295757 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
103295757 (RAF1)
04625 C-type lectin receptor signaling pathway
103295757 (RAF1)
04650 Natural killer cell mediated cytotoxicity
103295757 (RAF1)
04660 T cell receptor signaling pathway
103295757 (RAF1)
04662 B cell receptor signaling pathway
103295757 (RAF1)
04664 Fc epsilon RI signaling pathway
103295757 (RAF1)
04666 Fc gamma R-mediated phagocytosis
103295757 (RAF1)
04062 Chemokine signaling pathway
103295757 (RAF1)
09152 Endocrine system
04910 Insulin signaling pathway
103295757 (RAF1)
04929 GnRH secretion
103295757 (RAF1)
04912 GnRH signaling pathway
103295757 (RAF1)
04915 Estrogen signaling pathway
103295757 (RAF1)
04914 Progesterone-mediated oocyte maturation
103295757 (RAF1)
04917 Prolactin signaling pathway
103295757 (RAF1)
04921 Oxytocin signaling pathway
103295757 (RAF1)
04926 Relaxin signaling pathway
103295757 (RAF1)
04935 Growth hormone synthesis, secretion and action
103295757 (RAF1)
04919 Thyroid hormone signaling pathway
103295757 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
103295757 (RAF1)
04916 Melanogenesis
103295757 (RAF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
103295757 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
103295757 (RAF1)
04720 Long-term potentiation
103295757 (RAF1)
04730 Long-term depression
103295757 (RAF1)
04722 Neurotrophin signaling pathway
103295757 (RAF1)
09158 Development and regeneration
04360 Axon guidance
103295757 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103295757 (RAF1)
05206 MicroRNAs in cancer
103295757 (RAF1)
05205 Proteoglycans in cancer
103295757 (RAF1)
05207 Chemical carcinogenesis - receptor activation
103295757 (RAF1)
05208 Chemical carcinogenesis - reactive oxygen species
103295757 (RAF1)
05230 Central carbon metabolism in cancer
103295757 (RAF1)
05231 Choline metabolism in cancer
103295757 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103295757 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
103295757 (RAF1)
05212 Pancreatic cancer
103295757 (RAF1)
05225 Hepatocellular carcinoma
103295757 (RAF1)
05226 Gastric cancer
103295757 (RAF1)
05214 Glioma
103295757 (RAF1)
05221 Acute myeloid leukemia
103295757 (RAF1)
05220 Chronic myeloid leukemia
103295757 (RAF1)
05218 Melanoma
103295757 (RAF1)
05211 Renal cell carcinoma
103295757 (RAF1)
05219 Bladder cancer
103295757 (RAF1)
05215 Prostate cancer
103295757 (RAF1)
05213 Endometrial cancer
103295757 (RAF1)
05224 Breast cancer
103295757 (RAF1)
05223 Non-small cell lung cancer
103295757 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
103295757 (RAF1)
05161 Hepatitis B
103295757 (RAF1)
05160 Hepatitis C
103295757 (RAF1)
05164 Influenza A
103295757 (RAF1)
05163 Human cytomegalovirus infection
103295757 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
103295757 (RAF1)
05165 Human papillomavirus infection
103295757 (RAF1)
09171 Infectious disease: bacterial
05132 Salmonella infection
103295757 (RAF1)
05152 Tuberculosis
103295757 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
103295757 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
103295757 (RAF1)
09165 Substance dependence
05034 Alcoholism
103295757 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103295757 (RAF1)
01522 Endocrine resistance
103295757 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
efus01001
]
103295757 (RAF1)
Enzymes [BR:
efus01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103295757 (RAF1)
Protein kinases [BR:
efus01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
103295757 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RBD
C1_1
Kinase-like
ABC1
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
103295757
NCBI-ProteinID:
XP_008150445
LinkDB
All DBs
Position
18:34768612..34848887
Genome browser
AA seq
648 aa
AA seq
DB search
MEHIQGAWKTISNGFGFKDAVFDGPSCISPTIVQQFGYQRRASDDGKLMDSSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDMCQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNVRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNL
SPTGWSQPKTPVPAQRERAPGSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF
GTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIV
TQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGL
TVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYE
LMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFP
QILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
NT seq
1947 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggggcctggaagacgatcagcaatggttttggattcaaagatgca
gtgtttgatggccccagctgcatttctcccacaatagttcagcagtttggctatcagcgc
cgagcatcagatgatggcaaacttatggactcttctaagacaagcaatactatccgtgtt
ttcttgccaaacaagcaaagaacagtggtcaatgtgcgcaatggaatgagcttgcacgac
tgccttatgaaagctctcaaggtgaggggcctgcaaccagagtgctgcgcagtgttcaga
cttctccacgaacacaaaggtaaaaaagcacgtttagattggaatactgatgctgcctcc
ttgattggagaagaacttcaagtagacttcctggatcatgttcctctcacaacacacaac
tttgctcggaagaccttcctgaagcttgccttctgtgacatgtgtcagaagttcttgcta
aatggatttcgatgtcagacttgtggctacaaatttcacgagcattgtagcaccaaagta
cctactatgtgtgtggactggagtaatgtcagacaactgttattgtttccgaattccact
attggtgatagtggggtcccagcactgccttctttgacaatgcgtcggatgcgagagtct
gtttcccggatgcctgttagttcccagcacagatactccacaccccacgcctttacattc
aacacctccagcccctcctctgaaggttccctctcccagaggcagaggtcgacatccaca
cctaatgtccacatggtcagcactaccctccctgtggacagcaggatgattgaggatgca
atccgaagtcacagtgaatcagcctcaccttcagccttgtccagcagccccaacaatctg
agcccaacgggctggtcacagcccaaaacccctgtgccggcacagagagagcgggcacca
ggatctgggacccaggagaaaaacaaaattaggcctcgtggacagagagattcaagttat
tactgggaaatagaagccagtgaagtgatgctctccactcggattgggtcaggctccttt
ggaactgtttataagggcaagtggcatggagacgttgcagtaaagatcctaaaggttgtt
gaccccacaccagagcagtttcaggccttcaggaatgaggtggctgtcctgcgcaaaaca
cggcacgtgaacattctgctctttatggggtatatgacgaaggacaacctggcgattgtg
acccaatggtgtgagggcagcagcctctacaaacacctgcatgtccaagagaccaagttc
cagatgttccagttgattgacattgcccggcagacagctcagggaatggactacttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggcctg
acggtgaaaattggagattttggtttggcaacagtgaagtcacgctggagtggttctcag
caggttgaacaacccaccggctctatcctgtggatggccccagaggtgatccgaatgcag
gataacaacccgttcagcttccagtctgacgtctactcctacggcattgtgctgtacgag
ctcatgacaggggagctaccttactcccacatcaacaaccgagatcagatcatcttcatg
gtgggccgagggtatgcctccccagaccttagtaagctatacaagaactgccccaaagca
atgaagcggcttgtagccgactgtgtgaagaaagttaaggaagagaggcctctttttccc
cagatcctgtcgtccattgagctgctccaacactctctacccaaaatcaacaggagcgct
tctgagccatccctgcatcgggcagcccacaccgaggacatcaatgcctgcacactgacc
acgtcccctagactgcctgtcttctag
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