Eptesicus fuscus (big brown bat): 103296067
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Entry
103296067 CDS
T09083
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00790
Folate biosynthesis
efus01100
Metabolic pathways
efus01240
Biosynthesis of cofactors
efus01523
Antifolate resistance
efus04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
103296067 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
103296067 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103296067 (FPGS)
Enzymes [BR:
efus01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
103296067 (FPGS)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
103296067
NCBI-ProteinID:
XP_054582736
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Position
15:73680568..73694656
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AA seq
586 aa
AA seq
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MSRARSHLRANPFLAAVFPRGVTTRVTGRREFSARPAPQEPGMEYQDAVRTLNTLQTNAS
YLEQVKRQRGDPQAQLEAMKLFLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPEHFTKHFWRLYHRLEETKDGSSCVSMPAYFR
FLTLMAFHVFLQEKVDLAVMEVGIGGAYDCTNIVRKPVVCGVSSLGIDHTSLLGDTIEKI
AWQKGGIFKRGVPAFTVPQPDGPLAVLRERAEQICCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNATLALQLARCWLQRKDRQGIGELKVSRPSLLCQLPLAPVFQPTAHMRHGLRDTE
WPGRTQILCRGPLTWYLDGAHTSSSVQACVRWFRQALPRHRKRGPEVRVLLFNSTGDRDP
AALLKLLQPCQFDYAVFCPNLTEVSSAGNADQQNFMVTLDQVLLRCLEHQQHWSRLAEEA
ASPDLWSSPRPEAGGPASLLLAPRPPHTHGTSSLVFSCISHALQWISQGRDPVFQTPSSP
RDLLAHPVANSGASVLREAAAVHVLVTGSLHLVGGVLKLLDPSLSQ
NT seq
1761 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcacgtagccacctgcgcgcgaaccccttcctggcagcggttttcccgcgc
ggtgtgacgaccagggtcacgggaaggcgagagttcagcgcgcggcccgcgccgcaggag
cccggcatggagtaccaggatgctgtgcgcacactcaacaccctgcagaccaatgccagc
tacctggagcaggtaaagcgccagcggggtgacccccaggcacagctggaagccatgaag
ctgttcttggcacggagtgggctgcaggtggaggacttggaccagctgaacatcatccac
gtgactgggacgaaggggaagggctccacctgtgccttcaccgagcggatcctccggagc
tacggcctgaagacggggttctttagctctccccacctggtgcaggtgcgcgagcggatc
cgcatcaacgggcagcccatcagccccgagcacttcaccaagcacttctggcgcctctac
catcggctggaggagaccaaggacggcagcagctgtgtctccatgcctgcatacttccgc
ttcctcacgctcatggccttccatgtcttcctgcaagagaaggtggacctggcagtgatg
gaagtgggtattggtggggcttatgactgcaccaacatagtcaggaagcctgtggtgtgt
ggggtctcctctcttggcatcgaccacactagccttctgggggacacgatagagaagatc
gcatggcagaaagggggcatcttcaagcgtggcgtgcctgccttcaccgtgccccagcct
gatgggcccctggcagtgctgagggagcgtgctgagcagatctgctgtcccctctacctg
tgtccaccgctggaagccctggaggaaggggggccgccgttgaccctgggcctggaggga
gagcaccagcggtccaatgccacgttggccttgcagctggcccgctgctggctgcagcgg
aaggaccgccaaggcattggcgagctgaaagtgtccaggcccagcctcctgtgtcagctg
cccctggcacccgtgttccagcccacagcccacatgcggcatgggcttcgggacacggag
tggccaggccggacgcagatactgtgccgcgggccgctcacctggtacctggatggcgcg
cacacctccagcagcgtgcaggcctgcgtgcgctggttccgccaggcgctgccccgccac
cgcaagagggggcccgaggtgcgtgtcctgctcttcaactccacgggggaccgggacccg
gcggccctgctgaagctgttgcagccctgccagtttgactatgctgttttctgcccgaac
ctgacagaggtgtcatccgcgggcaacgcagaccagcagaacttcatggtgaccctggac
caggtgctgctccgctgcctggaacaccagcagcactggagccgcctggctgaggaggcg
gccagcccggacctctggagcagcccccgcccggaggctggtgggccggcatccctgctg
ctggcaccccgcccgccccacacccacggcaccagctccctcgtcttcagctgcatctcc
catgctttgcagtggatcagccagggccgggaccctgtctttcagacacccagttcccca
agggaccttctcgcccaccccgtggccaacagcggggccagcgtgctccgagaggccgct
gccgtccacgtgctggtcacaggcagcctgcacctggtgggcggcgtcctcaagctgctg
gatccctccctgtcccagtag
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