Eptesicus fuscus (big brown bat): 103296162
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Entry
103296162 CDS
T09083
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
103296162 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
efus03021
]
103296162 (SETX)
Enzymes [BR:
efus01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
103296162 (SETX)
5.6.2.5 RNA 5'-3' helicase
103296162 (SETX)
Transcription machinery [BR:
efus03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
103296162 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
UvrD-helicase
AAA_19
AAA_30
AAA_22
Viral_helicase1
ResIII
AAA_16
UvrD_C_2
nSTAND3
Helicase_RecD
Motif
Other DBs
NCBI-GeneID:
103296162
NCBI-ProteinID:
XP_054582887
LinkDB
All DBs
Position
15:complement(76548176..76606552)
Genome browser
AA seq
2679 aa
AA seq
DB search
MWLRSRNRMSTCCWCTPGGVSAIEFLQRYASRTQSSEFQTADDDLCYCLECVTEYHRARD
ELPFLHEVLWELETLRLVNHFEKSMKGEIDDDDDELYIIDNNGDAQPFDFTGQDFENKLR
VPLLEILKYPYLLLHEHVNELCVEALCRMEQANCSFQVFEKQPGIYLFLVHPNEMVRRWA
ILTAKGLGKVDRDDYYDLQEVLTCLFKVIELGLLENTDIYTTSVLEKGKLIILPPHMYDT
SNYKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMKKQTEDDSEDPFWPALH
CFMVILDRLGSKVWGQLIDPIEAFQTIIDNASYNREIQNIRNSSVRAKSEPESCLDDMVT
CSQIVYNFNPEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRLHNSTFLWF
IPFVQSLMDLNDLGMAYIVEVIHHLYSQVKDVLNQTAVMCDKVTEFFLLILVSVIELHRS
KKCLHLLWVSSQQWVDAIVKCAKLPTTAFARNSEKSSANGSKGAVMITSLSLHSVPSNSV
QLACVQLIRSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQETQELQTCLKQI
IRNIRLKMPQYTALAELAPPCKTSLASNGKEESEQIGKACEKDIPCLESCSPTCSKEAMK
ADVCQEQGSSIVSKASNTIEEEGNKQNYIKDLKLEDHLSAESHLKQSSKNLSTERTQDQV
KRHTKKQKSVKNNSYCTPQNCTSRNDPEEGCDRGVTMSAHLLTDSNTDSLEKAPTSKEDF
SLKNDVVGKTSKAKTKAQKSDICAKLSHVIKKQNRKSALVKNTVDLEGDVTVSDRENFCS
RTDTAGQKGDGCRQNFSLDPNDSLDHKNERQKSHNSLLLKELKKEKLDVPSAHENDCQIQ
ECHVDNKDFNSFTFMPKTSPCKDPVTLLGSKDKEINKSTDRVSSDLREQAPSSPQCDTLT
DSQIDRDLHKLSLIAQASVNNFPSDSTQKSSSQLQRKVKDKRSFRANHNHVRETCRGQVI
IISDDDDDEQIPDFEKHTKQEKMCIEKEWPGQGTSIANINVDMKPTKEEKTEDFEDSGSQ
VFEFESQQKVFSVWQDQKPHNRNSVQEDEKNSCLTYIADITNDWGYDTDYPMSEEVTKNE
ADGTEHAKPQNGSSVEEVCEIQVKKPKRKQLKKTMAEDSLRPSSSVRNKDQSDTLNERDL
TGNDTEIADIRTSPGPGVEKATPVSLKKSSPKHRTHSKVDRRASVSKTPKKTHSDTKKGQ
NKGSNYISCRSTPAIVLPKKPRQRPEPTSVAEKLGLKKAPRRAAELSQRSLDGIDKLRNH
GKIVGEIGTPKKTKLISPQSLPANDKKLLVSQDLQFQRQRRDKSHRNRQGLYDSADTTRA
GPHGAQNSDSVIPDIGRSDDSNKGGTEVMANSSGNQSIKCVSPEQGPGKEKYVSQVAGDA
CLLSPCSSPVLNGRIPTSEITVCTPEHPLGGGNLTGHHLEVPTWKRGQLDSDSDMEGDDI
FLTQHDPEDMDLCSQVQNDDDGLIEEVHWKSVQVEDSVNRPQSESLSITRCKYKDCVETV
KSQGEYCSKHSEAKAADDDVFRKPALPLSASKPLRPSTTKIFSSSSTSRLANFSKSLESA
PAPPGLRNKSNGGQPASKVPQPASPKPRAEPKSIYNIHSPTPNNSSRQAFKLPFAESRPF
SSSPVNMLLSSQSISDTFVKEVLKWKYEMFVKFDQCGPPTSLCQAISRPVPVRFQDCGDY
FDVFFPLLLLNAFETIAQEWINSPNKGKFYELKLRKFPAEYKKYWEFVVFLEEYELSKQL
HPKENDLVFLVPERLKGEKRDMERNSIPASRDYHCAYVQKFRRTPVMHNGKYECSLSIQT
QDNFPVKLNETVRCVVISSLVTTQRKLKAMSLLNSRNQLARAILNPNPMDFCTKDLLTTT
SERITAFLKDFNEDQKKAIETAYAMVKHSPAVAKICLIHGPPGTGKSRTIVGLLYRLLTE
KRGQLDENSNAKIKQNRVLVCAPSNGAVDELMKKIILEFKERCKDKKNPLGNCGDINLVR
LGPERSINSEVLKFSLDNQVNHRMKKDLPSYAQEMHRRKEHLDHQLDELSRQRALSRYGR
GIQRHELDEKIAQVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLES
AFRGQGGVPFSCVIVDEAGQACEVETLTPLIHRCNKLILVGDPKQLPPTVISLEPHQRQE
ARENLLHVRWAFPLQQAECSCVKRAQEYGYEQSMMARFCKLLEENVQHHVSGRLPVLQLT
VQYRMHPDICLFPSNYIYNKSLKTNRGTESIRCLSKWPFQPYLVFDVRDGSERRENDSYV
NVQEIKVVIELVKLLKDKRDVRCRTIGIITHYKAQKMMIQKELDKEFEEKGLAEVDTVDA
FQGRQKDCVIVTCVRANAMQGSIGFLASLQRLNVAITRAKYSLFILGHLRTLMDNQHWNH
LIQDAQRRGAIIKTCDKNYKQDVIKTLKLKSVLQRSLTYPPPTAPEGSSPQGSSLMRTWQ
DDGSNQASLDAREAAGKDPDRPPFKDQPRDPRLFRRMDAPGNCLRNPEPWGPQHPGAASA
SGEPSCPATPQALGHALEPCTATGSSHRPHVPCDPPAASVDSTNKSDQKGGHGHQRESRA
FSDRDQELLSPGSHHPKRSSSWDDGRTQEEDSGSKKRKL
NT seq
8040 nt
NT seq
+upstream
nt +downstream
nt
atgtggttgagatccaggaacagaatgagcacatgttgctggtgtacgccaggtggcgtt
tccgccattgagttcctacagcgctatgcatccaggacccagtccagtgaattccagaca
gcagatgatgacctctgctactgcttagagtgtgtgaccgagtaccacagagcaagggac
gaactgccattcttgcatgaggttttatgggaattagaaaccttacgtctcgtaaatcac
ttcgaaaaatctatgaaaggagaaatcgatgatgatgatgatgaattatatatcatagac
aacaatggagatgcacaaccatttgactttactggccaagactttgaaaataagctccga
gttcctcttctcgaaatcctgaaatacccttatctgcttttacatgagcatgttaacgag
ttatgtgttgaagcactttgtcggatggaacaagcaaattgctcctttcaggtttttgag
aaacagcccggaatctatttgtttttggtccatcccaacgaaatggttcgtcgttgggct
atcctgactgcaaaaggcttgggaaaagtggacagagacgattattatgacttacaagag
gttttgacttgcctttttaaagtcattgagttggggcttttagaaaatacagacatttat
actacttctgtccttgagaagggtaaactgatcatcctgcccccacacatgtatgacacg
tccaactacaagaactattggttaggtatttgcatgctgctgaccattctcgaggagcaa
gccatggattcactgttgttgggctcagacaaacagaatgatttcatgcagtcaatactt
cacaccatgaagaagcagacagaagatgatagtgaagatcctttctggccagcattgcac
tgtttcatggtcattttggatcgcctgggatctaaggtctggggtcaacttattgatcct
attgaggcctttcagaccattatcgacaatgcaagctacaatagagagatccagaatata
cgaaacagctctgtgagggccaagtcagaaccagagtcgtgtctggatgatatggtgact
tgcagccagattgtgtacaattttaacccagaaaagaccaaaaaggattcagggtggaga
tcagccatttgcccagattattgtcctaacatgtatgaagaaatggaaacattagccagc
gtgcttcagtcagatattggtcaagacatgcgtcttcacaacagcacatttctgtggttc
atcccttttgttcaatccctcatggatcttaatgatttgggtatggcttacatagtagag
gtcattcaccatctgtactcccaagtcaaagatgttctcaaccaaacagctgtgatgtgt
gacaaagtcactgaattttttctactaattttggtttcggtgattgaactacatagaagt
aaaaaatgtttgcatttgctgtgggttagctcccagcagtgggtagacgccattgtgaag
tgtgccaagcttcccactactgcatttgcacgaaattctgagaagtcatctgccaatggc
tccaaaggagcagtaatgataacgtctctgtcactgcattcagtgccatctaactctgta
caactcgcttgtgtgcagctgattagaagtctccttaaagaaggttatcagcttgggcag
cagactctttgtaagcgattctgggataagctcaacttattcctgcgaggaaatttatct
ctaggttggcagttgactagtcaggaaacgcaagaattacaaacttgtttaaagcaaatt
attagaaacataagactcaaaatgcctcaatatactgctttggcagagctggctcctcca
tgtaaaacctctcttgcctctaatggtaaagaagaaagtgaacaaatagggaaggcgtgt
gaaaaagacatcccctgtctggaaagttgcagcccaacatgttctaaagaagcaatgaaa
gctgatgtatgtcaagagcaagggagtagtatagtaagcaaagcaagtaacactatagaa
gaagaaggtaataagcaaaattacataaaagatttgaaactagaagaccatctctcagct
gagtcacacttaaagcagagtagtaaaaacctttccactgaaagaacccaagatcaagtt
aaaagacacacaaagaagcagaagtctgtaaaaaataattcctactgtacaccacagaac
tgtacttcaagaaatgatccagaagagggatgtgacagaggagtaactatgtcagcacat
ttgttgactgattctaacactgattctctggaaaaggcacccacatcaaaagaggatttc
tccctaaagaatgatgttgttggcaaaacctcaaaagcaaaaactaaggcacagaaaagt
gacatttgtgctaagttatcccatgtaataaagaagcaaaacaggaaaagtgccttggtc
aaaaatactgtggacttagagggagacgtgactgtctccgaccgtgagaatttctgttca
aggacagatactgcaggtcagaaaggcgatggctgcagacagaacttttctttagaccct
aatgatagtctggatcataaaaatgaaagacagaaatctcataacagtttattgctgaaa
gagttgaagaaggaaaagttagatgttccttctgcccatgaaaacgattgtcaaatacag
gaatgtcatgttgataataaagattttaactcatttactttcatgcctaaaacatctccc
tgtaaagatcctgtgactttacttggatcaaaagataaggagattaataagagcactgat
cgggtttcttctgacctgagagaacaggcccctagcagtcctcagtgtgacaccttaaca
gattctcagatagacagagacctccacaaattatctttaatagctcaagccagtgtcaat
aattttccatcagattcaactcaaaaaagctcatcccaattacagagaaaagtaaaagat
aaaagaagtttcagagccaaccacaatcatgtcagggaaacctgcaggggacaagttatt
atcatttcagatgatgatgatgatgaacaaattccagattttgagaaacacactaaacaa
gagaaaatgtgcattgagaaagaatggccagggcagggtacttcaatagctaatataaat
gtggacatgaagccaacaaaggaagaaaagacagaggactttgaggactctggttctcag
gtttttgagtttgaaagccaacagaaagtgttttcagtttggcaagatcagaaaccacac
aataggaattcagttcaagaggatgaaaaaaattcatgtttgacttatatagcagatatc
acaaatgattggggttatgatacagattaccctatgtctgaagaagttaccaaaaatgaa
gcagatggcactgagcatgcaaaaccacaaaatggtagttctgttgaggaagtttgtgaa
attcaagtaaaaaaacccaagagaaaacaattaaaaaaaacaatggctgaagattcttta
aggccttcatcttctgtcagaaataaggaccaatctgatactcttaatgagagagatcta
actggaaatgacactgaaattgcagacataaggacatcgcccggtccaggtgttgagaaa
gccactccggtttccctgaagaagtcatctccaaagcatcgaactcactccaaagtggat
cggagagcctcagtttctaaaacacctaagaaaacacattcagataccaaaaaagggcag
aataaaggttcaaattacataagttgcaggagcactcctgctatcgtgctaccaaaaaaa
cctcgccagcgtcctgaaccaacctcagtggctgagaagcttggtctgaaaaaggctcct
cgtcgggcagctgagttgtctcagcgatctttagacggtatagataaattacgcaaccat
ggcaaaattgttggagaaattggtacccccaaaaagactaaactaatttctcctcagagt
cttcctgcgaatgataagaaactgctcgtgagtcaagatcttcagtttcaaaggcagagg
agagacaaatctcatcgaaacagacaaggactttatgacagtgcagacacgacaagagct
ggaccacatggggcccagaattctgacagtgttataccagatataggtaggtcagatgac
agtaacaaaggaggaactgaggtcatggcaaacagtagtggaaatcagtcaataaaatgt
gtgtctcctgaacaaggacctgggaaagaaaaatatgtttctcaggtggctggtgatgct
tgtcttttgagcccttgtagttctcccgtgttaaatggaagaataccaaccagtgaaatt
acggtctgtactccggagcaccctttaggtggtggcaacctgactggacatcatttagag
gtgccaacttggaaaaggggacagcttgactccgacagtgatatggaaggagatgatatc
tttttaacacaacatgatcccgaagatatggacttatgttcacaagtgcagaatgatgat
gatggactcattgaagaagtccattggaaaagcgttcaagtagaggattctgtaaatcgg
cctcagtcagaatctttgagtatcacaagatgtaagtacaaagattgtgtggaaactgtg
aaaagccagggtgaatactgctcaaaacactctgaagctaaagcagcagatgacgatgtc
tttcgtaaacctgccctgcctctttctgcgtctaaacctttgagaccttccactacgaag
atttttagctcaagcagtacttcacgacttgctaatttttccaagtctttggaaagtgcc
ccggcacctccaggcctaagaaataagtcaaatggaggacagcctgcttcaaaagtacca
cagcctgcctctccaaagccaagggcagaaccaaagagtatatacaatattcattctcca
actccaaataattccagcaggcaagctttcaaactcccgtttgctgaaagcagacctttt
tcttcttctccggtcaacatgctcttatcatcacagtccatctctgacacctttgtcaaa
gaggtcttgaaatggaagtatgagatgtttgtgaagtttgaccaatgtgggcccccaaca
agtctttgtcaggccatctcaagacccgtgcctgtcagatttcaagattgtggagattac
ttcgatgttttcttccctttgttgctactgaatgcctttgaaacaatagcacaggaatgg
atcaactctccaaacaaaggaaaattctatgagttgaagttaagaaaatttcctgcagaa
tataaaaaatactgggagtttgtggtttttcttgaggaatatgaactgtctaaacagctt
catccgaaggagaatgacttggtgtttttggttcctgagagactgaaaggcgagaagaga
gatatggagcggaattccatcccagcctcccgtgactatcactgtgcttatgtccagaaa
ttccgccgcacgccagtcatgcataatgggaagtatgagtgttccctttctatccagacg
caggataacttcccagtcaaattaaatgaaaccgtgagatgtgttgtaatcagttctctg
gtaactacacaaaggaagttgaaagcaatgtctttgttgaatagtcgaaaccaactggcc
agagctattctgaatccaaaccccatggacttctgtacaaaagatctactaactacaaca
tctgagagaattacggccttcttaaaagatttcaacgaagaccagaagaaagcgatagaa
accgcgtatgccatggtgaagcactccccggcagttgccaagatctgtctgattcatggg
ccacctggaacagggaaatcaagaaccatcgttggcctcctgtaccgcctgctgaccgag
aagagggggcagctggatgaaaactccaacgccaagatcaagcagaaccgcgtgcttgtg
tgtgcgccttccaacggagctgtggacgagctgatgaaaaaaatcatcctcgaattcaaa
gaaaggtgtaaagataagaagaaccctctgggaaactgtggagatatcaatttagtacgt
ctgggtccagaaaggtctattaacagtgaggtcctaaaattcagcttggacaaccaagtg
aaccacagaatgaaaaaagacttaccttcttacgctcaggagatgcatagaagaaaggaa
catctagaccatcaactagatgaactttcccgccagcgtgctttaagccgatatggaaga
ggaatccagaggcacgaattagatgaaaaaattgcccaagtttcaaaagaaaggcaggaa
cttgcgtctaaaattaaagaggttcaagggcgcccacagaaaacccagagcatcatcatc
ctggagtcccacatcatctgctgcaccctgagcacgagcggcgggttgctgctcgagtcc
gctttccgggggcaaggaggcgtccccttcagctgtgtcatcgttgatgaggccgggcag
gcttgtgaagtggaaacccttacccccctcatccaccgctgcaacaagctaatcctcgtc
ggagacccgaagcagctcccccccaccgtcatctccttggagccgcatcagagacaagag
gctagagagaacctactccatgtgcgctgggcttttcctttgcaacaggcagagtgcagc
tgtgttaagagggcgcaggagtacggctacgagcagtccatgatggcccgcttctgcaag
ctgctggaggagaacgtgcagcaccacgtgagcggccggctgccggtgctccagctgacc
gtgcagtacaggatgcaccccgacatctgtctcttcccctccaactacatctacaacaag
agcctgaagaccaacagggggactgagagcattcggtgtttatcaaagtggccgtttcag
ccctacctcgtgttcgatgtcagagacggctcagaacgacgggaaaatgactcctatgtg
aatgttcaagagatcaaagtggtgatagaactggttaaacttctcaaagataaaagggac
gtgcgttgccgcaccatcggcataataacccactacaaggctcagaagatgatgattcag
aaggagctggacaaagaatttgaagagaaagggctggcagaagtagatactgtggatgca
ttccagggccgccagaaagactgtgttatagttacctgtgtcagggcaaacgccatgcaa
ggctccattggattcctggcgagtctgcagaggttgaacgtcgccattacacgagccaag
tacagcctcttcatccttgggcatctgaggaccctgatggacaatcagcactggaaccac
ctgattcaggacgcgcagaggcgtggcgccatcatcaagacctgcgacaagaactataag
caggatgtcatcaagaccctgaagctcaagtcggtgctgcagcggagtctgacctaccct
ccccctacagcccccgagggctccagcccccagggcagcagcctgatgaggacgtggcag
gatgacggctcgaaccaggcatccctggacgctagggaggctgctggaaaggaccctgac
cggcctccttttaaggaccagcctcgggacccacgcctgttcaggaggatggacgcccca
gggaactgcctacggaacccagagccctggggcccccagcaccctggagcagcctccgcc
tccggagagcccagctgccctgcgactccccaggctctgggccacgccttggagccgtgc
acggccacagggagcagccacaggcctcacgtgccatgtgaccctcctgccgccagcgtt
gactccaccaataaaagtgaccagaaaggcggtcacggccaccagagagagagcagggct
ttcagtgacagggaccaggagctgctcagccctgggagccatcaccccaagaggagctcc
agctgggacgatgggcgaacccaagaggaggacagcggttcgaagaagaggaagctttag
DBGET
integrated database retrieval system
