KEGG   Eptesicus fuscus (big brown bat): 103296227
Entry
103296227         CDS       T09083                                 
Symbol
ITGAM
Name
(RefSeq) integrin alpha-M isoform X1
  KO
K06461  integrin alpha M
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus04015  Rap1 signaling pathway
efus04145  Phagosome
efus04514  Cell adhesion molecule (CAM) interaction
efus04517  IgSF CAM signaling
efus04610  Complement and coagulation cascades
efus04613  Neutrophil extracellular trap formation
efus04640  Hematopoietic cell lineage
efus04670  Leukocyte transendothelial migration
efus04810  Regulation of actin cytoskeleton
efus05133  Pertussis
efus05134  Legionellosis
efus05140  Leishmaniasis
efus05146  Amoebiasis
efus05150  Staphylococcus aureus infection
efus05152  Tuberculosis
efus05202  Transcriptional misregulation in cancer
efus05221  Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    103296227 (ITGAM)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecule (CAM) interaction
    103296227 (ITGAM)
   04517 IgSF CAM signaling
    103296227 (ITGAM)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    103296227 (ITGAM)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103296227 (ITGAM)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    103296227 (ITGAM)
   04610 Complement and coagulation cascades
    103296227 (ITGAM)
   04613 Neutrophil extracellular trap formation
    103296227 (ITGAM)
   04670 Leukocyte transendothelial migration
    103296227 (ITGAM)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    103296227 (ITGAM)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    103296227 (ITGAM)
  09171 Infectious disease: bacterial
   05133 Pertussis
    103296227 (ITGAM)
   05134 Legionellosis
    103296227 (ITGAM)
   05150 Staphylococcus aureus infection
    103296227 (ITGAM)
   05152 Tuberculosis
    103296227 (ITGAM)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103296227 (ITGAM)
   05140 Leishmaniasis
    103296227 (ITGAM)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:efus04131]
    103296227 (ITGAM)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:efus04147]
    103296227 (ITGAM)
   04515 Cell adhesion molecules [BR:efus04515]
    103296227 (ITGAM)
   04090 CD molecules [BR:efus04090]
    103296227 (ITGAM)
   00536 Glycosaminoglycan binding proteins [BR:efus00536]
    103296227 (ITGAM)
Membrane trafficking [BR:efus04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    103296227 (ITGAM)
Exosome [BR:efus04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   103296227 (ITGAM)
Cell adhesion molecules [BR:efus04515]
 Integrins
  Integrin alpha subunits
   103296227 (ITGAM)
CD molecules [BR:efus04090]
 Proteins
  103296227 (ITGAM)
Glycosaminoglycan binding proteins [BR:efus00536]
 Heparan sulfate / Heparin
  Adhesion molecules of cell surface
   103296227 (ITGAM)
SSDB
Motif
Pfam: ITGAX-like_Ig_3 VWA FG-GAP Integrin_A_Ig_2 Integrin_A_Ig_1 VWA_2 FG-GAP_3 Integrin_alpha DUF2785
Other DBs
NCBI-GeneID: 103296227
NCBI-ProteinID: XP_008151001
LinkDB
Position
4:complement(6727172..6772127)
AA seq 1164 aa
MPTVTGCLLSPAMTDRVLLLTALALCHGFNLDTENPVIFRENARSFGQSVVQLEGSRVVV
GAPQEIKTPNQTGGLYQCDYSTSACEPIQLQVPPEAVNMSLGLSLAFATNPFRLLACGPT
LHQMCKENTYVNGFCFLFGSNLRQPPQRFPKALRECPQQESDIAFLIDGSGSINQNDFLR
MKDFVSTVMNQFTKSKTLFSLMQYSDEFRTHFTFQDFKANPDPRLLVRPIEQLKGWTHTA
TGIRKVVRELFDSKSGARKNALKILVVITDGKKYGDPLGYENVIAEADREGIIRYVIGVG
SAFDNRKSREELETIASKPSHDHVFQVTNFEALKTIQNQLQEKIFAIEGTQTGSTSSFEY
EMSQEGFSASITSNGPLLGAVGSFDWSGGAFLHMSEDKVAFINMTRINSDMNDAYLGYAA
EVVSWGQVQTLALGAPRYQHTGLVAMFRQSAGAWEVNAMIEGSQIGSYFGASLCSVDVNR
DGSSDLVLIGAPHYYEPTRGGRVSVCPLPRGRARWQCQAILRGEQGHPWGRFGAALTALG
DVNGDKLTDVAIGAPGEQENRGAVYLFHGTSGLGISPSHSQRIAGSQLSPTLQYFGQSLS
GGQDLTMDGLMDLAVGAQGQALLLRSQPVLRVEATMIFTPRELARSVFECRENVVRGLTA
GEVRVCLRVQKRTGDRLRPGEIQSTVTYDLALDSTRSRPRAILEETKNNTRRQTRVLGLS
QTCETLKLQLPECVEDSVTPVVLRLNFSLEGQPLTSYGNLRPVLAVDAPTVFTASLPFEK
NCGNDSVCQDALSVSFSFRNLHTLVVGGPRNFNVTVTVRNQGEDSFNTRVAFFYPPGLSY
RMVSGVQSQHSWRSWRVNCDSDPSTQTSTLHSGSCSINHPIFPGNSEVTFNITLDVDSDA
SLGDRLLLKANVTSENNSPRTNQTEFQLALPVKYAVYMVVSSREGSVKYLSFPASKKTSH
VINHQYQFTNLGQRSPRIGVVLWIPIRLNEVPVWGDPDAVFSPNLNRTCRREERVPPRSG
FLAELSKAPVLNCSVAVCLRVQCDFAESFGSREEFSVNLTGSLSFDWYIQTPHNHLQVVS
TAEILLDDRRFAQLPGQEALVRAQTETKVEPYEVHDPVPLIVGSSVGGLVLLGLITAAMY
KLGFFKRQYKDMMNEAAPEAAPPQ
NT seq 3495 nt   +upstreamnt  +downstreamnt
atgcccacagtcacagggtgcctgctctctccggccatgactgaccgagtccttctctta
acagccttggccttatgtcatgggttcaacctggacactgaaaacccagtgatctttcga
gagaatgcaaggagcttcgggcagagcgtggtccagcttgagggatcccgggtggtggtg
ggagccccccaggagataaagactcccaatcagacgggcggcctctaccagtgtgactac
agcacgtccgcctgcgagcccatccagctgcaggtccccccggaggctgtgaacatgtcc
ttgggtctgtctctggcatttgccaccaaccctttccggctgctggcctgcggccccacc
ctacaccaaatgtgcaaggagaacacctacgtgaacggcttctgcttcctgtttggatcc
aacctgcggcagccgccccagcggttccccaaggccctcagagagtgcccccagcaggag
agcgacatcgccttcttgattgatggctctggcagcatcaaccaaaatgactttcttcgg
atgaaggatttcgtctcaactgtgatgaatcagttcacaaagtccaaaaccttgttctct
ctgatgcagtactctgacgagttccggacgcatttcaccttccaagatttcaaggctaac
ccagacccgaggctactggtgaggccaatcgaacagctgaaagggtggacgcacacggcc
acgggaatccgcaaagtggtaagagaactgtttgacagcaaaagtggagcccggaagaat
gcccttaagatcctcgttgtcatcacagacggaaagaagtatggtgatcccttggggtac
gagaatgtcatcgcggaggcggacagggagggcatcattcgctacgtcattggggtgggc
agtgccttcgacaacaggaagtcccgcgaagagctggagaccatcgcgtccaagccgtct
cacgaccacgtgttccaggtgaccaactttgaagcgctgaagaccattcagaaccagctc
caggagaagatctttgcgattgagggtactcagacaggaagtaccagctccttcgagtat
gagatgtctcaggaaggcttcagtgcttccataacctccaatggccccttgctgggtgct
gtggggagctttgactggtctggtggagcctttctgcatatgtcagaggataaagtcgcc
ttcatcaacatgaccaggataaattcagacatgaacgatgcttacttgggttatgctgcc
gaagtcgtctcgtggggccaggtgcaaaccctggccttgggggctcctcgatatcagcac
actggcctggtggccatgttcagacagagcgctggtgcctgggaggtcaacgcgatgatc
gagggcagccagattggctcctacttcggggcctccctctgctccgtggacgtgaacaga
gatggcagctccgacctggtcctcatcggggctccccattactacgagccgacccggggg
ggccgggtgtctgtgtgccccttgccccgggggagggccaggtggcagtgccaggccatc
ctccgtggggagcagggccacccctggggccgctttggggcagccctgaccgcgctgggg
gacgtgaatggagacaagctgacggacgtggccatcggagccccgggggagcaggagaac
cgaggtgctgtgtacctgttccatgggacctcggggctgggcatcagcccctcccacagc
cagcggattgcaggctcccagctctcccccacgctccagtatttcgggcagtcactgagt
gggggccaggacctcacgatggacggcttgatggacctggctgtgggggcgcaggggcag
gcgctgctgctcaggtcccagcctgtgctgagagttgaggcgaccatgatcttcacgccc
agggaattggcgaggagtgtgtttgagtgtcgggaaaatgtggtgagaggcctaactgcg
ggggaggtcagagtctgcctccgtgtgcagaagcgcaccggggaccggctgagaccagga
gagatccagagcactgtcacctatgacctggctctagactccactcgctcacgtcctcgg
gccattttagaggagacgaagaacaacacacgcagacagacccgggtcttggggctgagt
cagacgtgtgagacactgaagctacagttaccggaatgtgtagaggactcagtgaccccc
gttgtcctgcgcctcaacttctctctggaggggcagcccttgacctcctacgggaacctg
cggcccgtgctggctgtggacgctccgactgtcttcacagcctcgcttccctttgagaag
aactgtggcaatgacagtgtctgccaggatgccctcagcgtcagcttcagtttcaggaac
ctgcacaccctggtggtgggtggtccccggaacttcaacgtgacggtgacggtgcggaac
cagggcgaggactccttcaacactcgggtcgccttcttctacccgcctggcttgtcctat
cggatggtgtcaggggtccagtcccagcactcatggcgatcctggcgtgtgaactgtgat
tcggacccctccacccaaaccagcaccttgcacagcggcagctgcagcataaaccacccc
atcttcccaggcaactcagaggtcacctttaacatcacattggacgtggactcggatgct
tcccttggagacagactgcttctcaaggccaatgtgaccagtgagaacaactcgccgaga
accaatcaaacggagttccagctggcgctgcctgtgaagtacgcggtctacatggtggtc
tccagccgtgagggctccgtcaaatatctcagcttcccagcttcaaagaagaccagccat
gttataaaccatcagtatcagttcaccaacctggggcagaggagcccccgcatcggcgtg
gtgctctggatccccatccggctgaacgaggtgcccgtgtggggcgaccccgacgccgtc
ttctccccgaacctgaacaggacatgccgcagggaggagagggtgccccctcgctccggc
ttcctggctgagctgagcaaggctccggtgctgaactgctccgtcgcggtgtgcctgcga
gtccagtgtgacttcgccgagtccttcggcagccgggaggagttcagcgtcaacctcaca
ggcagcctctcctttgactggtacatccagactccgcacaaccacctgcaggttgtgagc
acagcggagatcctgctggacgaccggaggtttgcccagctcccaggacaggaggcctta
gtgagggcccagacagagaccaaggtggagccctatgaggtgcacgacccggtcccgctc
atcgtgggcagctccgtgggggggctggtgctcctcggcctcatcaccgccgcaatgtac
aagctcggcttcttcaagcggcagtacaaggacatgatgaatgaagccgctcccgaagcc
gccccgccccagtag

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