KEGG   Eptesicus fuscus (big brown bat): 103296845
Entry
103296845         CDS       T09083                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus04010  MAPK signaling pathway
efus04012  ErbB signaling pathway
efus04620  Toll-like receptor signaling pathway
efus04664  Fc epsilon RI signaling pathway
efus04668  TNF signaling pathway
efus04912  GnRH signaling pathway
efus04926  Relaxin signaling pathway
efus04935  Growth hormone synthesis, secretion and action
efus04936  Alcoholic liver disease
efus05132  Salmonella infection
efus05135  Yersinia infection
efus05142  Chagas disease
efus05161  Hepatitis B
efus05166  Human T-cell leukemia virus 1 infection
efus05167  Kaposi sarcoma-associated herpesvirus infection
efus05169  Epstein-Barr virus infection
efus05208  Chemical carcinogenesis - reactive oxygen species
efus05417  Lipid and atherosclerosis
efus05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103296845 (MAP2K4)
   04012 ErbB signaling pathway
    103296845 (MAP2K4)
   04668 TNF signaling pathway
    103296845 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103296845 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    103296845 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103296845 (MAP2K4)
   04926 Relaxin signaling pathway
    103296845 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    103296845 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    103296845 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103296845 (MAP2K4)
   05161 Hepatitis B
    103296845 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103296845 (MAP2K4)
   05169 Epstein-Barr virus infection
    103296845 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103296845 (MAP2K4)
   05135 Yersinia infection
    103296845 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    103296845 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103296845 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    103296845 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103296845 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efus01001]
    103296845 (MAP2K4)
Enzymes [BR:efus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     103296845 (MAP2K4)
Protein kinases [BR:efus01001]
 Serine/threonine kinases: STE group
  STE7 family
   103296845 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 103296845
NCBI-ProteinID: XP_054564968
LinkDB
Position
20:complement(7308740..7419808)
AA seq 463 aa
MAAPSPSGGGSGGGSGSGSPGPVGSPAPGHPAVSSMQVNELELISFTLGFQINFCEKAQS
GNCDPLIFQGHWASQKMPDNPVPMQVSAGKRKALKLNFANPPFKSTARFTLNPNPTGVQN
PHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAV
KRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREVIHTSFLLSASSATGDCWI
CMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL
LDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGIT
LYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRP
KYKELLKHPFILMYEERTVEVASYVCKILDQMPASPSSPMYVD
NT seq 1392 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggctccggcggtggcagcggcagcggctccccg
ggccccgtggggtccccggcgccgggccacccggccgtcagcagcatgcaggtaaatgaa
ctggaacttatctcttttactttaggctttcagataaacttctgtgaaaaggcacaaagt
ggaaattgtgacccattaatcttccaggggcattgggcttctcagaaaatgcctgacaat
cctgtgccgatgcaagtgagcgcaggtaaacgcaaagcactgaagttgaattttgcaaat
ccacctttcaaatctacagcaaggtttactctgaatcccaatcctacaggagttcaaaac
ccacacatagagagactgagaacacacagcatcgaatcgtcaggaaaactgaagatctcc
cctgaacagcactgggatttcaccgcagaggacttgaaagacctgggagaaatcggacga
ggagcgtatggttctgtcaacaaaatggtccacaaaccaagtggacaaataatggcagtt
aaaagaattcggtcaacagtggatgaaaaagaacaaaagcaacttcttatggatttggat
gtagtaatgcggagtagtgattgcccatacattgttcagttttatggtgcactcttcaga
gaggtaatacacacttcctttctgctgtcagcatcctcagcaaccggtgactgttggatc
tgtatggaactcatgtctacctcgtttgataagttttacaaatatgtatatagtgtatta
gatgatgttattccagaagaaattttaggcaaaatcactttagcaactgtgaaagcacta
aaccacttaaaagaaaacttgaaaatcattcacagagatatcaaaccttccaatatcctt
ctggacagaagtggaaatattaaactctgtgactttggcatcagcggacagctcgtggac
tccattgccaagaccagagatgctgggtgtaggccgtacatggcaccagaaagaatagac
ccaagtgcatcacgacaaggctatgatgtccgctctgatgtctggagtttggggatcaca
ttgtacgagttggccacaggccgatttccttatccaaagtggaatagtgtatttgatcaa
ctaacgcaagtcgtgaaaggagaccccccgcagctgagtaattcggaggaaagggaattc
tccccgagtttcatcaactttgtcaacttgtgccttacaaaggacgaatccaaaaggcca
aagtataaagaacttctgaaacatccctttattttaatgtatgaagaacgtactgtagag
gtcgcaagctatgtttgtaaaatcctggatcaaatgccagcatctcccagctctcccatg
tatgtcgattga

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