Eptesicus fuscus (big brown bat): 103297187
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Entry
103297187 CDS
T09083
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus01521
EGFR tyrosine kinase inhibitor resistance
efus01522
Endocrine resistance
efus01524
Platinum drug resistance
efus04010
MAPK signaling pathway
efus04012
ErbB signaling pathway
efus04020
Calcium signaling pathway
efus04066
HIF-1 signaling pathway
efus04151
PI3K-Akt signaling pathway
efus04510
Focal adhesion
efus04520
Adherens junction
efus04530
Tight junction
efus05200
Pathways in cancer
efus05205
Proteoglycans in cancer
efus05206
MicroRNAs in cancer
efus05212
Pancreatic cancer
efus05213
Endometrial cancer
efus05215
Prostate cancer
efus05219
Bladder cancer
efus05223
Non-small cell lung cancer
efus05224
Breast cancer
efus05226
Gastric cancer
efus05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103297187 (ERBB2)
04012 ErbB signaling pathway
103297187 (ERBB2)
04066 HIF-1 signaling pathway
103297187 (ERBB2)
04020 Calcium signaling pathway
103297187 (ERBB2)
04151 PI3K-Akt signaling pathway
103297187 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103297187 (ERBB2)
04520 Adherens junction
103297187 (ERBB2)
04530 Tight junction
103297187 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103297187 (ERBB2)
05206 MicroRNAs in cancer
103297187 (ERBB2)
05205 Proteoglycans in cancer
103297187 (ERBB2)
05230 Central carbon metabolism in cancer
103297187 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
103297187 (ERBB2)
05226 Gastric cancer
103297187 (ERBB2)
05219 Bladder cancer
103297187 (ERBB2)
05215 Prostate cancer
103297187 (ERBB2)
05213 Endometrial cancer
103297187 (ERBB2)
05224 Breast cancer
103297187 (ERBB2)
05223 Non-small cell lung cancer
103297187 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103297187 (ERBB2)
01524 Platinum drug resistance
103297187 (ERBB2)
01522 Endocrine resistance
103297187 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
efus01001
]
103297187 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
efus04147
]
103297187 (ERBB2)
04090 CD molecules [BR:
efus04090
]
103297187 (ERBB2)
Enzymes [BR:
efus01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103297187 (ERBB2)
Protein kinases [BR:
efus01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
103297187 (ERBB2)
Exosome [BR:
efus04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
103297187 (ERBB2)
CD molecules [BR:
efus04090
]
Proteins
103297187 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
103297187
NCBI-ProteinID:
XP_054565831
LinkDB
All DBs
Position
20:42901923..42927127
Genome browser
AA seq
1260 aa
AA seq
DB search
MELAAWYRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPGNASLFFLQDIQEVQGYVLIAHSHVTQVPLQRLRIIRGTQLFEDNYALAVLDNG
DRLDSATPVAGAAPGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTVLWKDIFHKNNQLA
LTQIDTNRSRACKPCSPSCNPSHCWGESSKDCQILTRTLCASGCARCKGSLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTTCP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFEGDPASNTAPLEPKQLRVFETLEEITGYLYISAWPDSMP
DLSVFQNLQVIRGRVLHDGAYSLTLQGLGIRWLGLRSLRELGSGLALVHRNARLCFVHTV
PWERLFRNPHQALLHSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGHPREYVKDRYCLPCHPECQPQNGSATCLGSEADQCMACAHYKDSPFCVARC
PSGVKPDLSFMPIWKFPDEEGTCQPCPINCTHSCVDLDEKGCPAEQRASPVTSIIAAVVG
ILLAMVVGVVLGILIRRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEG
AGSDVFESDLGMGAAKGLQSLSPHDPSPLQRYSEDPTVPLPPETDGYVAPVTCSPQPEYV
NQPEVRLKPPSPLEGPLPPPRSASATLERPKTLSPKTLSPGKNGVVKDVFAFGGAVENPE
YLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSLPSTFEGTPTAENPEYLGLDAPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtaccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctccccgccagtcctgag
acccacctggacatgctccgccacctctaccagggctgtcaggtggtgcagggtaacctg
gagctcacctacctgcctggcaatgccagcctcttcttcctacaggacatccaggaggtg
cagggctacgtgctcatcgctcacagccacgtgacccaggtcccactgcagaggctgcga
atcatccgaggcacccagctctttgaggacaactatgccctggccgtgctggacaacgga
gaccggctggacagcgccacccctgtcgccggggccgccccaggagggctgcgggagctg
cagctgcgaagcctcacagagatcctgaagggaggggtcttgatccagcggaacccacag
ctctgccaccaggacacggttctgtggaaggacatcttccacaagaacaaccagctggcc
ctcacgcagatagacaccaaccgctcacgggcctgcaaaccctgttctccatcctgtaac
ccttcccactgctggggagaaagttccaaggactgtcagatcctgacgcgaactctgtgt
gccagcggctgtgcccgctgcaagggctcactgcccaccgactgctgccacgagcagtgt
gctgccggctgcacgggccccaagcactctgactgcctggcttgcctccacttcaaccac
agtggcatctgtgagctgcactgcccggccctggtcacctacaacacggataccttcgag
tccatgcccaaccccgagggccggtatacctttggtgccagctgtgtgaccacctgcccc
tacaactacctgtcaacggacgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacggctgaggacggaacacagcggtgtgagaagtgcagcaaaccctgtgcccga
gtgtgctatgggctgggcatggaacacctgcgggaggtgagggcagtcaccagtgccaat
atccaggagtttgccggctgcaagaagatctttgggagcctggcgtttctgccagagagc
tttgagggggaccccgcctccaacactgcgcccctagagcctaagcagctcagagtgttt
gagaccttggaggagatcacaggttacctgtacatctccgcgtggccagacagcatgcct
gacctcagtgtcttccagaacctgcaagtgatccggggacgcgttctgcacgacggcgcc
tactcgctgaccctgcaaggcctgggcatccgatggctggggctgcgctcgctgcgggaa
ctgggcagtgggctggccctcgtccaccgcaacgcccgcctctgctttgtacacacggtg
ccctgggagcggctcttccggaaccctcaccaggccctgctccacagtgccaaccggcca
gaggcagagtgcgtgggtgagggcctggcctgctacccgctgtgcgcccacgggcactgc
tggggcccggggcccacccagtgcgtcaactgcagccagttccttcggggccaggagtgc
gtggaggaatgccgcgtcctgcaggggcaccccagggagtacgtgaaggacaggtactgt
ctgccgtgccaccctgagtgccagccccagaatggctcagcgacctgcttaggatcggag
gctgaccagtgtatggcctgcgcccactacaaggactctcccttctgtgtggctcgatgc
cccagtggcgtgaaacctgacctctccttcatgcccatctggaagttccccgatgaggag
ggcacgtgccagccgtgccccatcaactgcacccactcctgcgtggacctggatgagaag
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgctgcggtggtgggc
attctgctggccatggtcgtgggggtggtcctcgggatcctgatcaggagaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggaaacggagctggtggagccgctg
acaccgagcggagcgatgcccaaccaggctcagatgcggatcctcaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcaccgtctacaagggcatctggatc
ccggatggggagaacgtgaagatcccagtggccatcaaagtattgagggaaaacacgtct
cccaaagccaacaaagaaatcttagatgaagcatacgtgatggctggcgtgggctccccc
tatgtgtcgcgcctcctgggcatctgcttgacctccacggtgcagctggtgacacagctc
atgccctatggctgcctcctggaccacgtccgagaacaccgcgggcgcctgggctcccag
gacctgctgaactggtgcgtgcagattgccaagggaatgagctacctggaggacgtgcgg
ctcgtgcacagggacctggctgcccggaatgtactggtcaagagtcccaaccacgtcaag
atcacggactttgggctggctcggctgctggacatcgatgagacggagtaccatgcggat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccgacggttcacc
caccagagtgatgtgtggagctacggggtgactgtatgggagctgatgacttttggggcc
aaaccttacgacgggatcccagcccgggagatccctgacctgctggagaagggcgaacgg
ctgccccagccgcccatctgcaccatcgatgtctacatgatcatggtcaaatgttggatg
attgactcggaatgccggcctcggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgcttcgtggttatccagaatgaggacttgggccctgccagccccttg
gacagcaccttctaccgatcgctgctggaggatgacgacatgggggacctggtggacgcg
gaggagtacctggtgccccagcaaggcttcttctgcccagaccctgccccgggtgcgggg
ggcacggcccaccgcaggcatcgcagctcctccaccaggagtggcggtggtgaactcaca
ctggggctggagccgtctgaggaggagcccccgaaatctccactggcaccctcagagggg
gcgggctctgatgtgtttgagagcgacttgggaatgggggcggccaaggggctgcagagc
ctctccccacatgaccccagccctctacagcggtacagtgaggaccccacggtacccctg
ccccctgagactgatggctacgtcgcccctgtgacctgcagtccccagccagaatacgtg
aaccagccagaggttcgcctgaagcccccctcacccctagagggccctctgccgcctcct
cgatctgccagtgccactctggaaaggcccaagactctctcacccaagactctgtcccct
gggaagaacggggttgtcaaagacgtttttgcctttgggggcgctgtggagaaccctgag
tacttggcgccccgaggcagggctgcccctcagccccaccctcctcccgccttcagccca
gcctttgacaacctctattactgggaccaggacccatcagagcgtggctctctgcccagc
acctttgaagggacccctacggcagagaaccccgagtacctgggcctggatgcgccagtg
tga
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integrated database retrieval system
