KEGG   Eptesicus fuscus (big brown bat): 103298707
Entry
103298707         CDS       T09083                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus01522  Endocrine resistance
efus04010  MAPK signaling pathway
efus04015  Rap1 signaling pathway
efus04068  FoxO signaling pathway
efus04071  Sphingolipid signaling pathway
efus04114  Oocyte meiosis
efus04148  Efferocytosis
efus04218  Cellular senescence
efus04261  Adrenergic signaling in cardiomyocytes
efus04370  VEGF signaling pathway
efus04380  Osteoclast differentiation
efus04517  IgSF CAM signaling
efus04550  Signaling pathways regulating pluripotency of stem cells
efus04611  Platelet activation
efus04613  Neutrophil extracellular trap formation
efus04620  Toll-like receptor signaling pathway
efus04621  NOD-like receptor signaling pathway
efus04622  RIG-I-like receptor signaling pathway
efus04625  C-type lectin receptor signaling pathway
efus04657  IL-17 signaling pathway
efus04658  Th1 and Th2 cell differentiation
efus04659  Th17 cell differentiation
efus04660  T cell receptor signaling pathway
efus04664  Fc epsilon RI signaling pathway
efus04668  TNF signaling pathway
efus04670  Leukocyte transendothelial migration
efus04714  Thermogenesis
efus04722  Neurotrophin signaling pathway
efus04723  Retrograde endocannabinoid signaling
efus04728  Dopaminergic synapse
efus04750  Inflammatory mediator regulation of TRP channels
efus04912  GnRH signaling pathway
efus04914  Progesterone-mediated oocyte maturation
efus04917  Prolactin signaling pathway
efus04926  Relaxin signaling pathway
efus04932  Non-alcoholic fatty liver disease
efus04933  AGE-RAGE signaling pathway in diabetic complications
efus04935  Growth hormone synthesis, secretion and action
efus04936  Alcoholic liver disease
efus05014  Amyotrophic lateral sclerosis
efus05020  Prion disease
efus05022  Pathways of neurodegeneration - multiple diseases
efus05132  Salmonella infection
efus05133  Pertussis
efus05135  Yersinia infection
efus05140  Leishmaniasis
efus05142  Chagas disease
efus05145  Toxoplasmosis
efus05152  Tuberculosis
efus05161  Hepatitis B
efus05163  Human cytomegalovirus infection
efus05167  Kaposi sarcoma-associated herpesvirus infection
efus05169  Epstein-Barr virus infection
efus05170  Human immunodeficiency virus 1 infection
efus05171  Coronavirus disease - COVID-19
efus05205  Proteoglycans in cancer
efus05208  Chemical carcinogenesis - reactive oxygen species
efus05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
efus05415  Diabetic cardiomyopathy
efus05417  Lipid and atherosclerosis
efus05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103298707 (MAPK11)
   04015 Rap1 signaling pathway
    103298707 (MAPK11)
   04370 VEGF signaling pathway
    103298707 (MAPK11)
   04668 TNF signaling pathway
    103298707 (MAPK11)
   04068 FoxO signaling pathway
    103298707 (MAPK11)
   04071 Sphingolipid signaling pathway
    103298707 (MAPK11)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    103298707 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103298707 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    103298707 (MAPK11)
   04218 Cellular senescence
    103298707 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103298707 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103298707 (MAPK11)
   04613 Neutrophil extracellular trap formation
    103298707 (MAPK11)
   04620 Toll-like receptor signaling pathway
    103298707 (MAPK11)
   04621 NOD-like receptor signaling pathway
    103298707 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    103298707 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    103298707 (MAPK11)
   04660 T cell receptor signaling pathway
    103298707 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    103298707 (MAPK11)
   04659 Th17 cell differentiation
    103298707 (MAPK11)
   04657 IL-17 signaling pathway
    103298707 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    103298707 (MAPK11)
   04670 Leukocyte transendothelial migration
    103298707 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103298707 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    103298707 (MAPK11)
   04917 Prolactin signaling pathway
    103298707 (MAPK11)
   04926 Relaxin signaling pathway
    103298707 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    103298707 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103298707 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    103298707 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    103298707 (MAPK11)
   04722 Neurotrophin signaling pathway
    103298707 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103298707 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103298707 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    103298707 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103298707 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    103298707 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103298707 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103298707 (MAPK11)
   05161 Hepatitis B
    103298707 (MAPK11)
   05171 Coronavirus disease - COVID-19
    103298707 (MAPK11)
   05163 Human cytomegalovirus infection
    103298707 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103298707 (MAPK11)
   05169 Epstein-Barr virus infection
    103298707 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103298707 (MAPK11)
   05135 Yersinia infection
    103298707 (MAPK11)
   05133 Pertussis
    103298707 (MAPK11)
   05152 Tuberculosis
    103298707 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103298707 (MAPK11)
   05140 Leishmaniasis
    103298707 (MAPK11)
   05142 Chagas disease
    103298707 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103298707 (MAPK11)
   05020 Prion disease
    103298707 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    103298707 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103298707 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    103298707 (MAPK11)
   05415 Diabetic cardiomyopathy
    103298707 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103298707 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    103298707 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103298707 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103298707 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efus01001]
    103298707 (MAPK11)
Enzymes [BR:efus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103298707 (MAPK11)
Protein kinases [BR:efus01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103298707 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH Kinase-like Cas_CT1975 FTA2
Other DBs
NCBI-GeneID: 103298707
NCBI-ProteinID: XP_054574563
LinkDB
Position
7:complement(107939760..107945368)
AA seq 364 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLVHARRTYRELRLLQHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPRKDLRSIFHGANPLAVDLLGRMLVLDSDQRLSAA
EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPGPPQPPGSL
DVEQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtccggccctcgcgccggcttctaccggcaggagctgaacaagacggtgtgggaggtg
ccgcagcggctgcaggggctgcgcccggtgggctcgggcgcctacggctccgtctgctcg
gcctacgacgcgcgtctccgccagaaggtggcggtgaagaagctgtcgcgccccttccag
tcgctggtccacgcgcggaggacctaccgggagctgcggctgctccagcacctgaagcac
gagaacgtcatcgggctgctggacgtcttcactccggccacgtccatcgaggacttcagc
gaagtgtacctggtgaccacgctgatgggcgccgacctcaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgtgcagttcctcgtgtaccagctgctgcgcgggctgaagtac
atccactcggccgggatcatccaccgggacctgaagcccagcaacctggcggtgaacgag
gactgcgagctcaggatcctggacttcgggctggcgcgccaggcagacgaggagatgacg
ggctacgtggccacgcgctggtaccgggcccctgagatcatgctcaactggatgcactac
aatcagacagtggacatctggtctgtgggttgcatcatggccgagctgctccaaggaaag
gccctcttcccgggaagtgactacattgaccagctgaagcgcatcatggaggtggtgggc
acgcccagcccggaggtgctggcaaagatatcctcggaacacgcccggacgtacatccag
tccctgcctcccatgccccggaaggacctcaggagcatcttccatggcgccaaccccctg
gccgtggacctcctgggaaggatgctggtgctggacagcgaccagaggctcagtgcggcc
gaggccctggcccacgcctacttcagccagtaccacgaccccgaggacgagcccgaggcc
gagccctatgacgagagcgtggaggcgaaggagcgcaccttggaggagtggaaggagctc
acctaccaggaagtcctcagcttcaagcccccagggccaccgcagcctccgggcagcctg
gacgttgagcagtga

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