Eptesicus fuscus (big brown bat): 103299396
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Entry
103299396 CDS
T09083
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00260
Glycine, serine and threonine metabolism
efus00630
Glyoxylate and dicarboxylate metabolism
efus00670
One carbon pool by folate
efus01100
Metabolic pathways
efus01200
Carbon metabolism
efus01230
Biosynthesis of amino acids
efus01240
Biosynthesis of cofactors
efus01523
Antifolate resistance
efus04981
Folate transport and metabolism
Module
efus_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
103299396 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
103299396 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
103299396 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
103299396 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103299396 (SHMT1)
Enzymes [BR:
efus01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
103299396 (SHMT1)
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Motif
Pfam:
SHMT
Aminotran_1_2
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
103299396
NCBI-ProteinID:
XP_054564978
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Position
20:complement(1838147..1870228)
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AA seq
484 aa
AA seq
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MATAVSRAPENADLWSSHDKMLAQPLKDGDVEVYNIIKKESHRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEILCQKRALQVYGLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRRGVRSTDPKTGKEILYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRVYQHQVVANCRALAEALKELGYKIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLETEFRK
VAHFIHKGIELTLQVQKAVGDKASLKEFKEKLAGDEQHRAATRALREEVESFASLFPLPG
LPDF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcgactgcggtgagcagggctcccgagaatgctgacctgtggtcctcgcatgacaaa
atgctggcacagcccctgaaagacggcgacgtcgaggtttacaacatcatcaagaaggaa
agtcaccggcagagggttggactagagctgatcgcctcggagaatttcgccagccgagcc
gttttggaggccctgggctcctgcttgaataacaagtactctgaggggtaccctggccag
aggtactacggcgggactgagtttatcgatgagctggagatcctctgtcagaagcgagcg
ctgcaggtctacggtctggacccccagtgctggggggtcaacgtccagccctactcgggc
tcccctgccaacttcgcagtgtacaccgccctggtggaaccccatgggcgcatcatgggc
ctggacctgcctgacggaggccacctgacccacgggttcatgacagacaagaagaaaatc
tctgctacatccatcttttttgaatccatgccctataaggtgaacccggacactggctac
atcaactacgaccagctggaggagaacgcccgcctcttccacccgaagctgattatcgca
ggaaccagctgctactcccgaaacctggactacgctcgattgcggaagattgccgatgac
aacggggcgtacctcatggccgacatggcacacatcagcgggctggtggcggctggcgtg
gtgccctcccccttcgaacactgccacgtggtgtccaccaccacccacaagaccctgcgc
ggctgccgcgccggcatgatcttctacaggcgaggagtgcgcagcacggatcccaaaacc
ggcaaagagatcctgtacaacctggagtcgctcatcaactctgctgtgttcccagggctg
cagggagggccccacaaccatgccattgctggggtggccgtggctctgaagcaggccatg
acgccagagttccgcgtgtaccagcaccaggtggtggccaactgcagggcgctggctgag
gccctgaaggagctgggctacaagatagtaacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacagatggtggccgggctgagaaggtgctagaagcctgt
tctattgcttgcaacaagaacacctgcccaggtgacagaagcgccctgcggcccagtggg
ctgcgactgggaaccccagcactgacgtcccgaggacttctggaaacagagttccggaaa
gtcgcccactttattcacaaagggatagagctgactctgcaggtccagaaggctgttggg
gacaaggccagcctgaaggagttcaaggagaagctagcaggggatgagcagcaccgcgcg
gccacccgagccctccgggaggaggtggagagcttcgcgtctcttttccctctgcccggc
ctgccggacttctag
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