KEGG   Eptesicus fuscus (big brown bat): 103299424
Entry
103299424         CDS       T09083                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus04010  MAPK signaling pathway
efus04015  Rap1 signaling pathway
efus04218  Cellular senescence
efus04380  Osteoclast differentiation
efus04620  Toll-like receptor signaling pathway
efus04664  Fc epsilon RI signaling pathway
efus04668  TNF signaling pathway
efus04750  Inflammatory mediator regulation of TRP channels
efus04912  GnRH signaling pathway
efus04935  Growth hormone synthesis, secretion and action
efus04936  Alcoholic liver disease
efus05014  Amyotrophic lateral sclerosis
efus05022  Pathways of neurodegeneration - multiple diseases
efus05132  Salmonella infection
efus05135  Yersinia infection
efus05145  Toxoplasmosis
efus05161  Hepatitis B
efus05163  Human cytomegalovirus infection
efus05167  Kaposi sarcoma-associated herpesvirus infection
efus05169  Epstein-Barr virus infection
efus05170  Human immunodeficiency virus 1 infection
efus05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
efus05417  Lipid and atherosclerosis
efus05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103299424 (MAP2K6)
   04015 Rap1 signaling pathway
    103299424 (MAP2K6)
   04668 TNF signaling pathway
    103299424 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    103299424 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103299424 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    103299424 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103299424 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    103299424 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103299424 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103299424 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103299424 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103299424 (MAP2K6)
   05161 Hepatitis B
    103299424 (MAP2K6)
   05163 Human cytomegalovirus infection
    103299424 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103299424 (MAP2K6)
   05169 Epstein-Barr virus infection
    103299424 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103299424 (MAP2K6)
   05135 Yersinia infection
    103299424 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103299424 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103299424 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    103299424 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103299424 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    103299424 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103299424 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efus01001]
    103299424 (MAP2K6)
Enzymes [BR:efus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     103299424 (MAP2K6)
Protein kinases [BR:efus01001]
 Serine/threonine kinases: STE group
  STE7 family
   103299424 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 103299424
NCBI-ProteinID: XP_008154482
LinkDB
Position
20:44680324..44784969
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggcctcaaaattccaaaagaagcattt
gaacagccccagaccagttccacgccgcctcgagatttagactccaaagcttgcatttct
atcggaaaccagaactttgaggtgaaggcagatgacctggagcctatcatggagctgggc
cgaggcgcgtacggagtggtggagaagatgagacacgtgcccagtgggcagatcatggca
gtgaagcggatccgggccaccgtgaacagccaggagcagaaaaggctactgatggacctg
gatgtctccatgaggacggtggactgtccctttaccgttaccttttacggcgcactcttc
cgggagggtgatgtttggatctgcatggagctcatggatacatcgctagataaattctac
aaacaagtgattgataaaggccaaaccattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagctttagagcatttacacagtaagctctccgtcatccatcgagacgtc
aagccttccaacgtgctgatcaatgctctgggccaggtgaagatgtgcgactttggcatc
agtggctaccttgtagactcggtggctaaaactatcgatgcaggatgcaaaccgtacatg
gctcctgaaaggataaacccggagctcaaccagaagggctacagtgtgaagtctgacatt
tggagtctgggcatcaccatgattgagttggccatccttcggtttccctacgattcatgg
ggaactcctttccagcagctcaaacaggtggtagaggagccgtcaccacagctgcccgca
gacaagttctccgaagagtttgtcgactttacctcgcagtgcttgaagaagaattccaaa
gaacggccaacatatccagagcttatgcaacatccgtttttcactctacatgaatccaaa
gcaacagacgtggcatcttttgtaaaattgattcttggagactaa

DBGET integrated database retrieval system