Eptesicus fuscus (big brown bat): 103300291
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Entry
103300291 CDS
T09083
Symbol
CHRNA4
Name
(RefSeq) neuronal acetylcholine receptor subunit alpha-4 isoform X1
KO
K04806
nicotinic acetylcholine receptor alpha-4
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus04080
Neuroactive ligand-receptor interaction
efus04082
Neuroactive ligand signaling
efus04725
Cholinergic synapse
efus05033
Nicotine addiction
efus05207
Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
103300291 (CHRNA4)
04082 Neuroactive ligand signaling
103300291 (CHRNA4)
09150 Organismal Systems
09156 Nervous system
04725 Cholinergic synapse
103300291 (CHRNA4)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
103300291 (CHRNA4)
09165 Substance dependence
05033 Nicotine addiction
103300291 (CHRNA4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
efus04040
]
103300291 (CHRNA4)
Ion channels [BR:
efus04040
]
Ligand-gated channels
Acetylcholine (nicotinic)
103300291 (CHRNA4)
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Motif
Pfam:
Neur_chan_memb
Neur_chan_LBD
Motif
Other DBs
NCBI-GeneID:
103300291
NCBI-ProteinID:
XP_054579976
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Position
12:703802..712989
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AA seq
617 aa
AA seq
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MELGGPWAPPPPLPLLLLLGAGLLPVSGHVETRVHAEERLLKKLFSGYNKWSRPVANISD
VVLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWRDYKLCWDPRDYENVTSIRIPSELIWR
PDIVLYNNADGDFAVTHLTKAHLFHDGRVQWRPPAIYKSSCSIDVTSFPFDQQNCTMKFG
SWTYDKAKVDLVSMHSHVDRLGFWESGEWVIMDAVGTYNTRKYECCAEVYPDITYAFVIR
RLPLFYTVNLLIPCLLLSCLTVLVFYLPSQCGEKVTLCISVLLSLTVFLLLITEIIPSTS
LVIPLIGEYLLFTMIFVTLSIIVTVFVLNVHHRSPRTHRMPAWVRRVFLDVVPRLIFMER
PPAVKGNCRRLIESVHRMASAPRFWPGPEEEPNFMSKVQSRGPSPTPSFCAPLDAPGKPQ
PACTSPSDQVPTLQPAETEKASPCRPTTSTRDPGLAKARSLSTQPMSSPNKAPEGGIRCR
SRSIQYCVPQDEAASQASGPVASSPPSWAELPPTDQASPCKCKCKEPSTGSSNTAFRALS
PKAPPHRLPLPPALTRAAEGVQHIADHLKAEDTDFSVKEDWKYVAMVIDRIFLWVFVIVC
LLGTAGLFLPPWLAGMI
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atggagctcgggggcccctgggcgccgccgccgccgctgccgctgttgctgctgctgggg
gccggcctcctgcccgtgagcggccacgtggagacgcgggtccatgcagaggaacggctg
ctgaagaagctcttctctggctacaacaagtggtcccggcccgtggccaacatctcggat
gtggtccttgtccactttggcctgtccatcgcacagctcattgacgtggacgagaagaac
cagatgatgacgacgaatgtgtgggtgaagcaggagtggcgggactataagctgtgctgg
gaccccagggactacgagaacgtgacttccatccgcatcccctccgagctcatctggcgg
ccagacatcgtgctctacaacaacgcggacggggacttcgctgtcacccacctgacgaag
gcccacctgttccacgacgggcgggtgcagtggaggccgcccgccatctacaagagctcc
tgcagcatcgacgtcacctccttcccctttgaccagcagaactgcaccatgaagttcggg
tcctggacctacgacaaggccaaggtcgacctggtgagcatgcacagccacgtggaccgg
ctgggcttctgggagagcggcgagtgggtcatcatggacgccgtgggcacctacaacacc
aggaagtacgagtgctgcgccgaggtgtaccccgacatcacctacgccttcgtcatccgg
cgcctgccgctcttctacacggtcaacctcctcatcccctgcctgctcctctcctgcctc
acggtgctggtcttctacctgccctcccagtgcggcgagaaggtcacgctgtgcatctcc
gtgctgctgtcgctcaccgtcttcctgctgctcatcaccgagatcatcccctccacctcc
ctggtcatcccgctcatcggcgagtacctgctcttcaccatgatcttcgtcacgctctcc
atcatcgtcaccgtcttcgtgctcaacgtgcaccaccgctcgccgcgcacccaccgcatg
cccgcctgggtgcgccgcgtcttcctggacgtcgtgccgcggctgatcttcatggaacgg
ccgcccgcggtcaagggcaactgccggcggctcatcgagtccgtgcacaggatggccagt
gcccctcgcttctggccggggcccgaggaggagcccaacttcatgagcaaagtccagagc
cggggcccctcgcccaccccgtccttctgtgctcccctggatgcgccaggcaagccccag
ccggcctgcacgtcgccctcagaccaggtgcccactctgcagccagcggagaccgagaaa
gccagcccctgccgcccaaccaccagcacccgggacccggggctcgccaaagcccggtct
ctgagcacccagcccatgtccagccccaacaaagcaccggagggcggcatccggtgccgg
tctcgaagcatccagtactgcgttcctcaagacgaggccgcctcccaggccagcggcccc
gtggccagctcccctccctcctgggctgagctcccacccacagaccaggcctctccctgc
aaatgtaagtgcaaggagccgtccacggggtcctcaaacacagcgttcagagccctcagc
cccaaagcaccgccccaccgcctgcccctgccgcccgccctgacacgggctgctgagggt
gtccagcacatcgcagaccacctgaaggcggaagacaccgacttctcggtgaaggaggac
tggaagtacgtggccatggtcatcgaccgcatcttcctctgggtgttcgtcatcgtctgc
ctgctggggaccgccggcctcttcctgccgccctggctggccggcatgatctag
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