Eptesicus fuscus (big brown bat): 103301133
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Entry
103301133 CDS
T09083
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus04217
Necroptosis
efus04380
Osteoclast differentiation
efus04620
Toll-like receptor signaling pathway
efus04621
NOD-like receptor signaling pathway
efus04630
JAK-STAT signaling pathway
efus04658
Th1 and Th2 cell differentiation
efus04659
Th17 cell differentiation
efus05145
Toxoplasmosis
efus05160
Hepatitis C
efus05161
Hepatitis B
efus05162
Measles
efus05164
Influenza A
efus05165
Human papillomavirus infection
efus05167
Kaposi sarcoma-associated herpesvirus infection
efus05168
Herpes simplex virus 1 infection
efus05169
Epstein-Barr virus infection
efus05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
103301133 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
103301133 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
103301133 (TYK2)
04621 NOD-like receptor signaling pathway
103301133 (TYK2)
04658 Th1 and Th2 cell differentiation
103301133 (TYK2)
04659 Th17 cell differentiation
103301133 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
103301133 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
103301133 (TYK2)
05160 Hepatitis C
103301133 (TYK2)
05171 Coronavirus disease - COVID-19
103301133 (TYK2)
05164 Influenza A
103301133 (TYK2)
05162 Measles
103301133 (TYK2)
05168 Herpes simplex virus 1 infection
103301133 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
103301133 (TYK2)
05169 Epstein-Barr virus infection
103301133 (TYK2)
05165 Human papillomavirus infection
103301133 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
103301133 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
efus01001
]
103301133 (TYK2)
Enzymes [BR:
efus01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103301133 (TYK2)
Protein kinases [BR:
efus01001
]
Non-receptor tyrosine kinases
JAK family [OT]
103301133 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
Kdo
FERM_C_FAK1
Kinase-like
ABC1
RIO1
Motif
Other DBs
NCBI-GeneID:
103301133
NCBI-ProteinID:
XP_054573420
LinkDB
All DBs
Position
6:24097180..24118354
Genome browser
AA seq
1188 aa
AA seq
DB search
MPLCHGGATARGSKPDGDEAPLTAITGGLKVFLHWAGPASKEPWVTFSEATLTAEEVCIH
IAHKVGITPPCFNLFALFDAQAQVWLPPNHILEVSRDTNLTLHFRMRFYFRNWHGTNPQE
PAVCRCRPPGAKASSEQAEQGIQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
KNESLGMAFLHLCHLALCRGVPLEKVAKKISFKDCIPRSFRQQIRQYNAFTRLRLRIIFR
RFLHAFQPGSLSQHVVMVKYLATLERLAPRFGTERVPVCHLELLAQAEGEPCCVQDSAQA
PGDPKLKSAVEPPTHEVLVTGTGGIQWRPIQTEVRGFQSPHGGDGGSSRNSHADLSGKKA
KAQQLGGPPVDRPREAPWAYFCDFQDITHVVLRECHVSIHCQDKRLELTLPSPAIALSLV
SLVDGYFRLTADSNHYLCHEVAPPRLVMSIQDGVHGPLLDPFVLAKMQREEGLYLIHWST
SHFNRLILTVAQRDQAPGTPCLRLWKFPIELCEGTVRLQSWDRSFPSVRELRAALQGCSL
RAGDHCFSLRHCCLPQPGEISNLIIMRGPQASTRSLNLSQLSFHRVCHDDLTQLSHLGQG
TRTNVYEGLLRVGGGGPEEDQAYDGDPTLPAGGHGQELRVVLKVLDTSHYDITLAFYETA
SLMSQVSHVHLTFVHGVCVHGSKNIMVTEFVEHGPLDVWLRRERGRVPVAWKVAVAQQLA
SALSYLEDKRLAHGNVCGRNILLARLGLAEGTSPFIKLSDPGMGLGALSREERVERIPWI
APECLFGGANSLSTAADKWGFGATLLEICFDGEAPLQDRSPSEKEYFYQKQHPLPEPSCP
ELATLTSQCLTYEPAQRPSFRTILRDLTHLQPQNLVEILYVNPTSPASDPTVFHKRYLKK
IRDLGEGHFGKVSLYCYDPTNEGTGEMVAVKALKADCGPQLRTGWRREIDILRTLYHEHI
VKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHHVGLAQLLLFAQQICEGMAYLHTQHY
VHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGYEYYRVREDGDSPVFWYAPECLKECKFY
YASDVWSFGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPEK
CPHEIYVLMKNCWEAEASFRPTFQNLIPILKTAHEKYRGQAPSVFSVG
NT seq
3567 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccatgggggggccaccgccaggggcagcaagcccgatggggacgaagct
ccgctcacagccatcacaggaggcctgaaggtgttcctgcactgggcgggccctgccagc
aaggagccctgggtcactttcagcgaggccacactgaccgcggaggaggtctgcattcac
atcgcacacaaagtcggcatcactccaccctgtttcaatctctttgccctctttgatgcc
caggcccaggtctggctgcccccaaaccacattcttgaggtctccagagacacaaacttg
acgctgcacttccgcatgaggttttatttccggaactggcatggcacaaaccctcaggag
ccagctgtgtgtcgctgcaggcccccgggggccaaggcttcgtcagaacaggcagagcag
gggatacaactcctggacccagcctcctttgagtacctctttgagcagggcaagcatgag
tttgtgaatgatgtggcatcgctgtgggagctgtcgagtgaggaggagatccaccacttt
aagaacgagagcctgggcatggcctttctgcacctctgtcaccttgctctctgccgcggt
gttcccctggagaaggtggccaagaagatcagcttcaaggactgtatcccgcgctccttc
cggcaacagatccggcagtacaatgcgttcacacggctacgcctgcggatcatcttccgc
aggttcctgcacgccttccagccgggcagcctttcccagcacgtcgtcatggtcaagtac
ctggccacactcgagcggctggcaccccgcttcggcacggagcgtgtgcctgtgtgccac
ctagagctgctggcccaggccgagggggagccctgctgtgtccaggacagtgcgcaggcc
cctggagatcccaagctcaagtctgcggtcgaaccgcccacccacgaggtgctggtgact
ggcactggcggcatccagtggcggccaatacagacagaggtgcggggtttccagagtccc
catggtggtgacggtggcagcagcaggaattctcatgctgacttatctgggaagaaagcc
aaggcccagcagctgggcggcccacctgtggacaggccgcgggaggcgccatgggcctac
ttctgtgacttccaggacatcacccacgtggtgctgagagaatgccatgtcagcatccac
tgtcaggacaagcgcctggagctgaccctgccttccccggccatcgccctgtccttggtg
tcgctggtggatggctatttccgcctgacggctgactcgaaccactacctgtgccacgag
gtggctcctccacggctggtgatgagcatccaggacggtgtccacggacccctgctggat
ccctttgtgctggccaagatgcagcgggaggagggcctctatcttatccactggagcacc
agccacttcaaccgcctcatcctcacggtggcccagcgggaccaggcacctggcacgccg
tgtctgcgcctgtggaagttccccattgagctgtgtgagggcaccgtcaggctgcagagc
tgggaccggtccttccccagcgtgcgggagctgcgggctgccctgcagggctgctcactg
cgggccggtgaccactgcttctccctgcgccactgctgcctgccgcagccaggagagatc
tccaacctcatcatcatgcgggggcctcaagccagcaccaggtctctcaacctcagccag
ctcagcttccaccgggtctgccatgatgacctcacccagctgtcccacttgggccagggc
acgaggaccaatgtgtatgagggcctcttgagagttgggggcggaggccctgaggaggac
caagcatatgatggggaccccaccttgcccgccgggggccatgggcaggagctgcgagta
gtgctgaaggtgttagacacgagtcactatgacatcaccctggctttctacgagacggcc
agcctcatgagccaggtgtcccacgtgcacctgaccttcgtccacggtgtctgcgtgcat
ggctctaaaaatatcatggtgacagagttcgtggagcatggacccctggacgtgtggctg
cggcgggagaggggccgtgtgcctgtggcctggaaggtggcagtggcccagcagctggcc
agtgccctcagctacctggaggacaagcgcctggctcatggtaacgtgtgtggccggaac
atcctgctggcacgtctagggctggcggagggcaccagccccttcatcaaactgagcgac
cctggcatgggcctgggtgccctctccagggaggagcgggtagagcggatcccctggatc
gcccccgagtgcctgttcggtggggctaacagcctaagcaccgccgctgacaagtggggc
tttggtgccaccctcctggagatctgcttcgatggggaggcccccctgcaggaccgcagc
ccctccgagaaagagtacttctaccagaagcagcaccccctgcctgaaccctcatgcccg
gagctagccacactcaccagccagtgcctgacctatgagccggctcagcggccttccttc
cgcaccatccttcgtgacctcactcaccttcagccccaaaatcttgttgaaatcttgtat
gtgaatccaacctcgccagcatcagaccccactgttttccacaagcgctacttgaaaaag
atccgggatctgggtgagggtcacttcggcaaggtcagcctgtactgctatgacccgacc
aacgaaggcactggcgagatggtggccgtgaaggctctcaaggcggactgcggccctcag
ctccgcactggctggaggcgggagatcgacatcctgcgcacgctctaccacgagcacatc
gtcaagtacaagggctgctgtgaggaccaaggcgagaaatcggtccagctggtcatggag
tacgtgcctctgggcagcctccgagactacctgccccggcaccacgtagggctggcccag
ctgctgctgtttgcccagcagatctgcgagggcatggcctacctgcacacccagcactac
gtccaccgagacctggctgcccgcaacgtgctgctggacaacgacaggctggtcaagatc
ggggactttggcctggccaaggccgtgcccgaaggctacgagtactaccgtgtgcgcgag
gatggcgacagccccgtgttctggtatgctcctgagtgcctgaaggagtgtaagttctac
tatgcatctgatgtctggtcctttggagtcaccatgtatgagctgctgacctactgtgac
tccagccaaagccccccctcgaaattcatcgagctcataggcctcacccaggggcagatg
acagtactgaggctcactgagctgctggaacgaggggagaggctgccacggccagagaaa
tgtccccatgagatctatgtcctcatgaagaactgctgggaggcagaggcctcatttcgc
ccgaccttccagaacctcatacccatcctgaaaacggcccacgagaaataccggggccag
gccccctccgtgttcagtgtcggctaa
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integrated database retrieval system
