Eptesicus fuscus (big brown bat): 103301470 Help Entry 103301470         CDS       T09083                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism efus  Eptesicus fuscus (big brown bat) Pathway efus00230   Purine metabolism efus01100   Metabolic pathways efus01522   Endocrine resistance efus04015   Rap1 signaling pathway efus04020   Calcium signaling pathway efus04022   cGMP-PKG signaling pathway efus04024   cAMP signaling pathway efus04062   Chemokine signaling pathway efus04072   Phospholipase D signaling pathway efus04081   Hormone signaling efus04082   Neuroactive ligand signaling efus04114   Oocyte meiosis efus04211   Longevity regulating pathway efus04213   Longevity regulating pathway - multiple species efus04261   Adrenergic signaling in cardiomyocytes efus04270   Vascular smooth muscle contraction efus04371   Apelin signaling pathway efus04540   Gap junction efus04611   Platelet activation efus04713   Circadian entrainment efus04714   Thermogenesis efus04723   Retrograde endocannabinoid signaling efus04724   Glutamatergic synapse efus04725   Cholinergic synapse efus04727   GABAergic synapse efus04742   Taste transduction efus04750   Inflammatory mediator regulation of TRP channels efus04911   Insulin secretion efus04912   GnRH signaling pathway efus04913   Ovarian steroidogenesis efus04914   Progesterone-mediated oocyte maturation efus04915   Estrogen signaling pathway efus04916   Melanogenesis efus04918   Thyroid hormone synthesis efus04921   Oxytocin signaling pathway efus04923   Regulation of lipolysis in adipocytes efus04925   Aldosterone synthesis and secretion efus04926   Relaxin signaling pathway efus04927   Cortisol synthesis and secretion efus04928   Parathyroid hormone synthesis, secretion and action efus04934   Cushing syndrome efus04935   Growth hormone synthesis, secretion and action efus04970   Salivary secretion efus04971   Gastric acid secretion efus04972   Pancreatic secretion efus04976   Bile secretion efus05032   Morphine addiction efus05163   Human cytomegalovirus infection efus05166   Human T-cell leukemia virus 1 infection efus05200   Pathways in cancer efus05207   Chemical carcinogenesis - receptor activation efus05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:efus00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103301470 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103301470 (ADCY4)    04371 Apelin signaling pathway     103301470 (ADCY4)    04020 Calcium signaling pathway     103301470 (ADCY4)    04072 Phospholipase D signaling pathway     103301470 (ADCY4)    04024 cAMP signaling pathway     103301470 (ADCY4)    04022 cGMP-PKG signaling pathway     103301470 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     103301470 (ADCY4)    04081 Hormone signaling     103301470 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103301470 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     103301470 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103301470 (ADCY4)    04062 Chemokine signaling pathway     103301470 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     103301470 (ADCY4)    04923 Regulation of lipolysis in adipocytes     103301470 (ADCY4)    04912 GnRH signaling pathway     103301470 (ADCY4)    04913 Ovarian steroidogenesis     103301470 (ADCY4)    04915 Estrogen signaling pathway     103301470 (ADCY4)    04914 Progesterone-mediated oocyte maturation     103301470 (ADCY4)    04921 Oxytocin signaling pathway     103301470 (ADCY4)    04926 Relaxin signaling pathway     103301470 (ADCY4)    04935 Growth hormone synthesis, secretion and action     103301470 (ADCY4)    04918 Thyroid hormone synthesis     103301470 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     103301470 (ADCY4)    04916 Melanogenesis     103301470 (ADCY4)    04925 Aldosterone synthesis and secretion     103301470 (ADCY4)    04927 Cortisol synthesis and secretion     103301470 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103301470 (ADCY4)    04270 Vascular smooth muscle contraction     103301470 (ADCY4)   09154 Digestive system    04970 Salivary secretion     103301470 (ADCY4)    04971 Gastric acid secretion     103301470 (ADCY4)    04972 Pancreatic secretion     103301470 (ADCY4)    04976 Bile secretion     103301470 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     103301470 (ADCY4)    04727 GABAergic synapse     103301470 (ADCY4)    04725 Cholinergic synapse     103301470 (ADCY4)    04723 Retrograde endocannabinoid signaling     103301470 (ADCY4)   09157 Sensory system    04742 Taste transduction     103301470 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     103301470 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     103301470 (ADCY4)    04213 Longevity regulating pathway - multiple species     103301470 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     103301470 (ADCY4)    04714 Thermogenesis     103301470 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103301470 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     103301470 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103301470 (ADCY4)    05163 Human cytomegalovirus infection     103301470 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     103301470 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103301470 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103301470 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103301470 (ADCY4) Enzymes [BR:efus01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103301470 (ADCY4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  103301470 NCBI-ProteinID:  XP_008156665 LinkDB All DBs Position 5:complement(78093643..78110076) Genome browser AA seq 1077 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLAIVLCALLALLTVAWASGRELASDPG FLTTVLCALGGFSLLLGLASCEQRLQRWTRPLSGLVWAALLALGHGFLFTGGVVSAWDQV SFFLFVIFTTYAMLPLGMRDATAAGLTSSLSHLLVLGLYLGPQLDSRPALLPQLAANAVL FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVEDAPIEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR YLESWGAAKPFAHLSHVESPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDDEMDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFLSNFI IQMLVTNRPPALAITYSITFLLFLLLLFVCFSEHLTRCVLKGPKMLHWLPALSGLVATRP GLRVVLGTATILLIFTMAITSLFFLPAASNCPFRAPNVSSMAFNLSWELPGSLPLISIPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLAASCCLFLHSHAWLSDCLVARLYLGSLDS RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRAGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgactcttcagtccccggccgccacccagcgaagacctcttctatgagacctac tacagcctgagccaacagtacccgctcctgctcctgctgctggcgatcgtgctctgcgcg ctcctggcgctgctgaccgtggcctgggccagcggcagggagctggcctcagacccgggc ttcctgaccacagtgctgtgcgcgctgggcggcttctcgctgctgctgggcctggcttcc tgcgagcagcgactgcagcgctggacgcgtccgctgtcgggcctcgtgtgggcagcgctg cttgcgttaggccacggcttcctattcactgggggcgtggtgagcgcctgggaccaggtg tcctttttcctctttgtcatcttcactacgtatgccatgttgcccttgggcatgcgggac gccacagctgcgggcctcacctcctccctctcacacctgctggtcctcgggctgtatctt gggcctcaactagactcaagacctgcgctgctgccgcagttggcagcaaacgcggtgttg ttcctgtgcgggaatgtggcgggagcgtaccacaaggcgctgatggagcgcgcactgcgc gccaccttccgagaggcgctcagttccttgcactcgcgccggcggctggacacggagaag aagcaccaggaacaccttctcttgtccatccttcctgcctacttggcccgagagatgaag gcagagatcatggcacggctgcaggctggacaggggtcaaggccagagagcaccaacaac ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatagtg ggcttcacacggctggccagtgagtgctccccaaaggagttggtgctcatgctcaatgag ctctttggcaagtttgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg ggagactgttactactgtgtctccgggctgcccctctccttaccagaccacgccatcaac tgcgtgcgcatggggctggacatgtgccgggccatcaggaaactacgagcagccaccggt gtggacatcaacatgcgcgtgggtgtgcactcgggcagcgtgctctgtggagtcatcggg ctgcagaagtggcagtatgatgtctggtcccatgacgtcacactggccaaccacatggag gcaggtggcgtgccaggacgagtacatatcacaggggctaccctggccctgctggcagga gcttacgctgtggaggatgcacccatagaacaccgggacccataccttcgggagctaggg gagcctacgtacctggtcatcgatccccgggctgaggaagaggatgaaaagggcactgca ggggggttgctgtcctctcttgagggccccaagatgcgtccatcactgctgatgacccgc tacctggaatcctggggtgcagccaagccttttgcccacctgagccacgtagagagccct gtgtccacctccactcctctcccggagaaggccctggcttccttcagcccccagtggagc ctggaccggagccgtacaccccggggactagatgatgaaatggacactggggatgccaag ttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcaatcaaaggacttc aacccactgacactttacttccgagagaaggaaatggagaaagagtatcgactctctgca ctccctgcctttaaatactatgcagcctgcacattcctggtttttctctccaacttcatc atccagatgctggtgacaaacaggcccccagctctggccatcacctatagcatcaccttc ctcctcttcctcctcctcctcttcgtctgcttctcagagcacctgacgaggtgcgtcttg aaaggccccaagatgctgcactggctgcctgcattgtctggcctggtggccacacggcct ggactacgagtcgtcctgggcactgccaccatcctcctcatctttaccatggccattacc agcctgttcttcttaccggcagcatcaaactgcccttttcgggctcccaatgtgtcctcc atggctttcaacctctcctgggagctccctgggtccctgcctctcatcagtattccatac tccatgcactgctgcgtgctgggtttcctctcctgctccctctttctgcacatgagcttc gagctgaagctgctgctgctcctgctatggctggcggcctcctgctgtctcttcctgcac tcccacgcctggctgtccgactgcctcgtcgcccgcctctatctgggctccttggactcc aggccaggggtgctgaaggagcccaaactgatgggagctatctccttcttcatcttcttc ttcacactccttgtcttggctcggcagaatgaatattattgccgcctggatttcctgtgg aagaagaagctgaggcaggagcgggaggaaacagagacgatggagaatctgactcggctg ctcttggagaatgtgctgcctgcacacgtggccccccagtttattggccagaaccggcgc aatgaggacctctaccaccagtcctatgagtgtgtctgtgtcctcttcgcctcagtccca gacttcaaggagttttactctgaatccaacatcaaccacgaggggctagagtgtctgcgg ctgctcaatgagatcattgctgattttgatgagctgctctctaagcccaagttcagtggg gtggagaagatcaaaaccatcggcagcacctacatggcagctacaggcttaaatgccacc tctggacaggatgcacagcaggatgctgagcgaagctgcagccacctaggcaccatggtg gaatttgcagtggcccttgggtctaagctggacgttatcaacaagcactcattcaacaac ttccgcttgcgtgtggggctaaaccatggaccagtagtggccggagtgataggagcccag aaaccacaatatgacatctggggcaacacggtgaatgtggccagtcgcatggagagcaca ggagtcctgggcaagatccaagtgactgaggagacagcccgggccctgcagtccttaggc tacacctgctacagcaggggtgtcatcaaagtcaaaggcaaagggcagctgtgtacctac ttcctcaacacagacttgacacgagctggacctccctcagccaccctaggctga

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