Eptesicus fuscus (big brown bat): 103303711
Help
Entry
103303711 CDS
T09083
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus04010
MAPK signaling pathway
efus04020
Calcium signaling pathway
efus04022
cGMP-PKG signaling pathway
efus04024
cAMP signaling pathway
efus04260
Cardiac muscle contraction
efus04261
Adrenergic signaling in cardiomyocytes
efus04270
Vascular smooth muscle contraction
efus04723
Retrograde endocannabinoid signaling
efus04725
Cholinergic synapse
efus04726
Serotonergic synapse
efus04727
GABAergic synapse
efus04911
Insulin secretion
efus04912
GnRH signaling pathway
efus04921
Oxytocin signaling pathway
efus04924
Renin secretion
efus04925
Aldosterone synthesis and secretion
efus04927
Cortisol synthesis and secretion
efus04929
GnRH secretion
efus04934
Cushing syndrome
efus04935
Growth hormone synthesis, secretion and action
efus05010
Alzheimer disease
efus05020
Prion disease
efus05022
Pathways of neurodegeneration - multiple diseases
efus05207
Chemical carcinogenesis - receptor activation
efus05410
Hypertrophic cardiomyopathy
efus05412
Arrhythmogenic right ventricular cardiomyopathy
efus05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103303711 (CACNA1S)
04020 Calcium signaling pathway
103303711 (CACNA1S)
04024 cAMP signaling pathway
103303711 (CACNA1S)
04022 cGMP-PKG signaling pathway
103303711 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
103303711 (CACNA1S)
04929 GnRH secretion
103303711 (CACNA1S)
04912 GnRH signaling pathway
103303711 (CACNA1S)
04921 Oxytocin signaling pathway
103303711 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
103303711 (CACNA1S)
04924 Renin secretion
103303711 (CACNA1S)
04925 Aldosterone synthesis and secretion
103303711 (CACNA1S)
04927 Cortisol synthesis and secretion
103303711 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
103303711 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
103303711 (CACNA1S)
04270 Vascular smooth muscle contraction
103303711 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
103303711 (CACNA1S)
04725 Cholinergic synapse
103303711 (CACNA1S)
04726 Serotonergic synapse
103303711 (CACNA1S)
04723 Retrograde endocannabinoid signaling
103303711 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
103303711 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
103303711 (CACNA1S)
05020 Prion disease
103303711 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
103303711 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
103303711 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
103303711 (CACNA1S)
05414 Dilated cardiomyopathy
103303711 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103303711 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
efus04040
]
103303711 (CACNA1S)
Ion channels [BR:
efus04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
103303711 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
GPHH
Ca_chan_IQ
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
103303711
NCBI-ProteinID:
XP_054568865
LinkDB
All DBs
Position
24:982823..1022228
Genome browser
AA seq
1861 aa
AA seq
DB search
MEPASPQDEGLRKKQPKKPAPEVLPRPPRALLCLTLDNPLRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNSLNVGLEKLEYFFLIVFSVEAAMKIIAYGFLFHPDAYLRS
GWNVLDFIIVFLGVFTVILEQVNLIQSNTTPLSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYYIGTDVVATEENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKHQLD
EDLRGYMSWITQGEVMDVDDLREGKLSLEEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRRKCHDVVKSRAFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLCLFAAEML
MKMYGLGLRQYFLSVFNRFDCFVVSSGLLEVLLVEAGAMSPLGISVLRCIRLLRLFKVTK
YWTSLSNLVASLLNSIRSIASLLLLLFLFVVIFALLGMQLFGGRYDFEDTEVRRSNFDSF
PQALVSVFQVLTGEDWNSVMYNGILAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPGRSEEEKAVVAKKPDQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKFRVLCHRIVNATWFTNFILLFIMLSSAALAAEDPIQAESMRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLPSSSISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFIFACVGVQLFKGKFFSCNDL
SKMTEKECRGYYYIYKDGDPTQIELRPREWVHNEFHFDNVLSAMMSLFTISTFEGWPQLL
YKAIDAYEEDQGPVHNHRVEMAIFFIVYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMILKLMAFKAKGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGTVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTPINRNNNFQTFPQAVLLLFRCA
TGEAWQEVLLASSYGKLCDPASEYAPGEEYSCGTNFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKEAKDANTVQI
QAGLRTIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNYLDRP
GSLAPVLANQRPLQFSDIEMEELESPVFLEDFPQDGSAHPLARANTNNANANVATGNSSH
SDRQAFSRVRYERESPEETGMPAARGGVLGPRSQSRVEQPRREGQLPRRAGPPAQAAPAP
GQEQRPRAEPPVPEVEEAPPCGRTPESPSRGLAPATALLIQQALLRGGLDTLAADTGFVS
ATGQALAEACQMAPEEVEAAATELLRRRESPGALGPPSLRSSVGSLDQRQGSQETLIPPR
P
NT seq
5586 nt
NT seq
+upstream
nt +downstream
nt
atggagccggcctccccccaggacgagggcctgaggaagaagcagcccaagaagccggcc
cccgaggtcctgcccaggcccccccgggccctgctgtgcctgaccctggacaaccccctg
cggaaggcctgcatcagcatcgtcgagtggaaacccttcgagaccatcatcttactgacc
atcttcgccaactgcgtggccctggccgtgtacctgcccatgcccgaggatgacaacaac
tccctgaacgtcggcctggagaagctggagtacttcttcctcatcgtcttctccgtcgag
gccgccatgaagatcatcgcctacggcttcctcttccacccggacgcctacctgcgcagc
ggctggaacgtgctggacttcatcatcgtcttcctgggggtcttcacggtgatcctggag
caggtcaacctcatccagagcaacaccacgccgctgagcagcaagggcgccggcctggac
gtcaaggcgctccgggccttccgcgtgctgcgccccctccggctggtgtcgggggtaccc
agcctgcaggtggtgctcaactccatcttcaaggccatgctgcccctgttccacatcgcc
ctgctggtcctcttcatggtcatcatctacgccatcatcggcctcgagctcttcaagggc
aagatgcacaagacctgctactacatcgggaccgacgtcgtggccacggaggagaacgag
aagccgtcgccctgcgcccggaccggctcgggccgtccctgcaccatcaacggcagcgag
tgccggggcggctggccgggcccgaaccacggcatcacgcacttcgacaacttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgtcctgtactgg
gtcaacgacgccatcgggaacgagtggccctggatctactttgtcaccctcatcctgctg
ggctcgttcttcatcctcaacctggtgctgggggtgctgagcggggagttcaccaaggag
cgggagaaggccaagtccaggggaaccttccagaagctgcgggagaagcatcagctggac
gaggacctccggggctacatgagctggatcacgcagggcgaggtcatggacgtggacgac
ctgcgagaagggaagctgtccttggaggaaggcggctccgacacggagagcctgtacgag
atcgagggcctgaacaagatcatccagtttgtccgacactggaggcagtggaaccgtatc
ttccgccggaaatgccacgacgtggtcaagtcccgggccttctactggctggtgatcctg
atcgtggctctcaacaccctgtccatcgcctccgagcaccacaaccagccgctgtggctg
acccacctgcaggacgtggccaaccgggtgctgctgtgcctgttcgcggcggagatgctg
atgaagatgtacgggctgggcctgcggcagtacttcctgtccgtcttcaaccgcttcgac
tgcttcgtggtgagcagcggcctcctcgaggtgctgctggtggaggccggcgccatgagc
ccgctgggcatctccgtgctgcgctgcatccgcctgctgcggctcttcaaggtcaccaag
tactggacgtcgctgagcaacctggtggcgtcgctgctgaactcgatccgctccatcgcg
tcgctgctgctgctgctcttcctcttcgtcgtcatcttcgcgctgctgggcatgcagctc
ttcgggggccgctacgacttcgaggacacggaggtgcgccgcagcaacttcgacagcttc
ccgcaggcgctcgtcagcgtcttccaggtcctgaccggggaagactggaactcggtgatg
tacaacggcatcctggcctacggcgggccctcctaccccgggatgctcgtgtgcatttac
ttcatcatcctcttcgtctgcggcaactacatcctgctcaacgtcttcctggccatcgcc
gtggacaacctggccgaggccgagagcctgacctccgcccagaaggccaaggccgaggag
cggaagcgcaggaagatgtccaagggcctcccgggccggtccgaggaggagaaggccgtg
gtggccaagaagccggaccagaagcccaagggcgagggcatcccgaccacggccaagctg
aagatcgacgagttcgagtccaacgtcaacgaggtgaaggacccctacccctcggccgac
ttccccggcgacgacgaagaagatgagcccgagatccccgtgagcccgcgcccgcggccc
ctggccgagctgcagctgaaggagaaggcggtgcccatccccgaagccagctccttcttc
atcttcagccccaccaacaagtttcgcgtcctctgtcatcgcatcgtcaacgccacctgg
ttcaccaacttcatcctgctcttcatcatgctcagcagcgccgccctggccgccgaggac
cccatccaggccgagtccatgaggaaccagatcctcgggtattttgacatcgccttcacc
tctgtcttcactgtggagattgtcctcaagatgacgacctacggcgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggccgtgtccctc
atctccatggggctcccgtccagctccatctccgtggtgaagatcctgagggtgctgagg
gtgctccgacccctgcgagccatcaaccgagccaaagggctgaagcacgtggtgcagtgc
gtgttcgtggccatccgcaccatcggcaacatcgtcctggtcaccaccctcctgcagttc
atcttcgcctgcgtcggggtccagctcttcaaggggaagttcttcagctgcaatgacttg
tccaagatgacggagaaggaatgcaggggctactactacatctacaaggacggggacccc
acgcagattgagctgcgcccccgcgagtgggtgcacaatgagttccacttcgacaacgtg
ctgtcggccatgatgtccctcttcaccatctccaccttcgaggggtggccgcagctcctg
tacaaggccatcgacgcctacgaggaggaccagggccccgtccacaaccaccgcgtggag
atggccatcttcttcatcgtctacatcatcctcatcgccttcttcatgatgaacatcttc
gtgggcttcgtcatcgtcaccttccaggagcagggcgagaccgagtacaagaactgcgag
ctggacaagaaccagcgccagtgcgtgcagtacgccctgaaggcccgccccctgaggtgc
tacatccccaagaacccgtaccagtaccaggtgtggtacgtggtcacctcgtcctacttc
gagtacctcatgttcgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcggaggagatgaaccacatctcggacatcctcaacgtggccttcaccatcatc
ttcaccctggagatgatcctcaagctcatggcgttcaaggccaagggctacttcggggac
ccctggaacgtgtttgacttcctgatcgtcatcggcagcatcatcgacgtcatcctcagc
gagatcgacaccttcctggcctccagcggggggctgtactgcctgggtggcggctgcggc
accgtggaccccgacgagagcgcccgcatctccagcgccttcttccgcctgttccgggtc
atgaggctgatcaagctgctgagccgggccgagggcgtgcgcaccctgctctggaccttc
atcaagtccttccaggccctgccctacgtggccctgctcatcgtcatgctgttcttcatc
tacgccgtcatcggcatgcagatgttcgggaagatcgccttggtggacgggaccccgata
aaccgcaacaacaacttccagaccttcccgcaggccgtgctgctgctcttcaggtgtgcg
acgggcgaggcctggcaggaggtcctgctggccagcagctacgggaagctgtgcgacccg
gcgtccgagtacgcgcccggcgaggagtactcgtgcggcaccaacttcgcctactactac
ttcatcagcttctacatgctctgcgccttcctgatcatcaacctgttcgtggccgtcatc
atggacaacttcgactacctcacgcgggactggtccatcctgggccctcaccacctggac
gagttcaaggccatctgggcggagtacgacccggaggccacgggccgcatcaaacacctg
gacgtggtgacgctgctgcggcggatccagcccccgctgggcttcgggaagttctgcccc
caccgcgtggcctgtaagcggctcgtgggcatgaacatgcccctcaacagtgacggcacc
gtcaccttcaacgccaccctcttcgccctggtgcgcaccgccctcaagatcaagacggaa
gggaacttcgagcaggccaacgaggagctgagggccatcatcaagaagatctggaagagg
accagcatgaagctcctggaccaggtcatccctcccatcggagatgacgaggtgacggtg
ggcaagttctacgccacgttcctcatccaggagcacttccgcaagttcatgaagcggcag
gaggagtactacggctaccggcccaagaaggaggccaaggacgccaacaccgtgcagatc
caggccggactgcggaccatagaggaggaggcggcgccagagatccgcaggacgatctcg
ggagacctgacggccgaggaggagctggagagggccatggtggaggccgccatggaggag
gggatcttccggaggaccgggggcctgttcggccaggtggacaactacctggaccggccc
ggctccctggcgcccgtcctggccaaccagcggcccctgcagttttccgacatcgagatg
gaggagctggagtcgcccgtcttcctggaggacttcccgcaggacggcagcgcccacccg
ctggcccgcgccaacaccaacaacgccaacgccaacgttgccacgggcaacagcagccat
agcgaccgccaggcgttttccagggtccgctatgaacgggagtcccccgaggagaccggg
atgccggctgccagaggaggggtcctgggaccccgcagccagtcccgcgtggagcagcca
aggcgggaaggacagctgccccggagagcggggcccccagcccaggcggctcccgcgccc
ggtcaggaacagcgccccagggcggagcccccggtgccggaggtagaggaagcccccccc
tgcggccggacccccgagagcccttccaggggcctggctcccgccaccgccctgctgatc
cagcaggctctgcttcgaggcggcctggacacgctggcggccgacaccggcttcgtctcg
gcaacgggccaggccctggcggaggcctgccagatggcgccggaggaggtggaggccgcg
gccacggagctgctgagaaggcgagagtcccccggcgccctgggacccccgagcctccgg
tcctccgtgggcagcctcgaccagcgtcagggctcccaggagaccctcattcccccccgg
ccctga
DBGET
integrated database retrieval system
