KEGG   Eptesicus fuscus (big brown bat): 103303990
Entry
103303990         CDS       T09083                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X2
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus04010  MAPK signaling pathway
efus04015  Rap1 signaling pathway
efus04218  Cellular senescence
efus04620  Toll-like receptor signaling pathway
efus04664  Fc epsilon RI signaling pathway
efus04668  TNF signaling pathway
efus04714  Thermogenesis
efus04750  Inflammatory mediator regulation of TRP channels
efus04912  GnRH signaling pathway
efus04935  Growth hormone synthesis, secretion and action
efus04936  Alcoholic liver disease
efus05014  Amyotrophic lateral sclerosis
efus05022  Pathways of neurodegeneration - multiple diseases
efus05132  Salmonella infection
efus05135  Yersinia infection
efus05145  Toxoplasmosis
efus05161  Hepatitis B
efus05169  Epstein-Barr virus infection
efus05170  Human immunodeficiency virus 1 infection
efus05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
efus05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103303990 (MAP2K3)
   04015 Rap1 signaling pathway
    103303990 (MAP2K3)
   04668 TNF signaling pathway
    103303990 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    103303990 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103303990 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    103303990 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103303990 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    103303990 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103303990 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    103303990 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103303990 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103303990 (MAP2K3)
   05161 Hepatitis B
    103303990 (MAP2K3)
   05169 Epstein-Barr virus infection
    103303990 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103303990 (MAP2K3)
   05135 Yersinia infection
    103303990 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103303990 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103303990 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    103303990 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103303990 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103303990 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efus01001]
    103303990 (MAP2K3)
Enzymes [BR:efus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     103303990 (MAP2K3)
Protein kinases [BR:efus01001]
 Serine/threonine kinases: STE group
  STE7 family
   103303990 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase APH RIO1
Other DBs
NCBI-GeneID: 103303990
NCBI-ProteinID: XP_008159166
LinkDB
Position
20:complement(221323..248031)
AA seq 347 aa
MESPAPSPPAGVPPAKGKAKRKKDLRIACVSKPPAPSPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKGMEIPEDILGEIAVSVVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMAHPFFTLHKAKETDIAAFVTEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgccccgagcccgcctgccggcgtgccccccgccaaaggaaaggccaag
aggaagaaggacttgcggatagcctgtgtgtccaagccacccgcgcccagccccacgccc
cctaggaacctggactcccggaccttcatcaccattggagacaggaactttgaggtggag
gccgatgacctggtgaccatctcggagctcgggcgtggagcctacggcgtggtggagaag
gtgcggcacgcccagagtggcaccatcatggctgtgaagcggatccgggccaccgtgaac
tcccaggagcagaagcgcctgctcatggacttggatgtgaacatgcgcacagtcgactgc
ttctacaccgtcaccttctacggggccctcttccgagagggagacgtgtggatctgcatg
gagctcatggacacgtccctggacaagttctaccggaaggtgcttgaaaaaggcatggag
attcccgaggacattctgggggagattgctgtgtctgtggtgagggccctggagcacctg
cacagcaagctgtccgtcattcacagagatgtaaagccttcgaacgtcctcatcaacaag
gagggccacgtgaagatgtgtgacttcgggatcagcggctacttggtggattctgtggcc
aagaccatggacgccggctgcaagccctacatggcccccgagaggatcaacccggagctg
aaccagaagggctacaacgtgaagtccgacgtctggagcctcggcatcaccatgattgag
atggccatcctgcggttcccctacgagtcctgggggacccccttccagcagctgaagcag
gtggtggaagagccgtcccctcagctcccggctgaccgcttctctccggagtttgtggac
ttcactgcccagtgcctgaggaagaaccccgcggagcgcatgagctacctggagctgatg
gcgcaccctttcttcaccttacacaaagccaaggagacggacatcgctgcctttgtgacg
gagatcctgggagaggactcgtag

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