Eptesicus fuscus (big brown bat): 103304344
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Entry
103304344 CDS
T09083
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00020
Citrate cycle (TCA cycle)
efus00480
Glutathione metabolism
efus01100
Metabolic pathways
efus01200
Carbon metabolism
efus01210
2-Oxocarboxylic acid metabolism
efus01230
Biosynthesis of amino acids
efus04146
Peroxisome
efus05230
Central carbon metabolism in cancer
Module
efus_M00009
Citrate cycle (TCA cycle, Krebs cycle)
efus_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
103304344 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
103304344 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
103304344 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
103304344 (IDH2)
Enzymes [BR:
efus01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
103304344 (IDH2)
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
103304344
NCBI-ProteinID:
XP_054569221
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Position
25:4370823..4393658
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AA seq
452 aa
AA seq
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MAGYLRVVRSLGKASGSGPAWAPAALTGPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKDKLILPHVDVQLKYFDLGLPNRDKTDDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTMPITIGRHAHGDQYK
ATDFVADRAGTFKMVFTPKDGSGAKEWEVFNFPAGGVGMGMYNTDESISGFANSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQDIYEKHYKTEFEKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFSQTLEKVCVQTVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKNNLDKALGQK
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggctggctacctgcgggtcgtgcgatcgctcggcaaggcgtcgggctccgggccggcg
tgggcgccagccgccctgacgggccccaacttgcaggagcagccgcggcgccactatgcc
gacaagaggatcaaggtggccaagccggtggtggagatggacggcgatgagatgacccgt
atcatctggcagttcatcaaggacaagctcatcctgccccacgtggatgtccagctcaag
tatttcgacctggggctcccaaaccgtgacaagactgacgaccaggtcaccatcgactcg
gcattggccacccagaagtacagcgtggccgtcaagtgcgccaccatcactcctgatgag
gcccgggtggaagagttcaagctgaagaagatgtggaagagtcccaacggaaccatccgg
aacatccttggcgggactgtcttccgggagcccattatctgcaagaacatcccccgtctg
gtccccggctggaccatgcccatcaccattggcaggcacgcccatggcgaccagtacaag
gccacggactttgtggccgaccgggccggcaccttcaagatggtgttcaccccaaaggat
ggcagcggtgccaaggagtgggaggtgttcaacttccctgctggcggcgtgggcatgggc
atgtacaacacggacgagtccatctcgggttttgcgaacagctgcttccagtacgccatc
cagaagaagtggccgctgtacatgagcacgaagaacaccatcctgaaagcctatgacggg
cgcttcaaagacatcttccaggatatctatgagaagcattataagaccgagttcgagaag
aataagatctggtacgagcaccggctcattgatgacatggtggctcaggtcctcaagtct
tcaggcggctttgtgtgggcctgcaagaactatgatggagacgtgcagtcggacatcctg
gcccagggcttcggctccctgggcctgatgacgtccgtgctggtctgccccgacggaaag
accatcgaggctgaggctgctcacgggacagtcacgcgccactatcgggagcaccagaag
ggccggcctaccagcaccaaccccatcgccagcatcttcgcctggacgcgaggcctggag
caccggggaaagctggacgggaaccaggatctcatcaggttctcccagaccctggagaag
gtgtgcgtgcagacagtggagagcggagccatgaccaaggacctggcgggctgcatccac
ggtctcagcaacgtgaagctcaacgaacacttcctgaacacctcggacttcctggacacc
atcaagaacaacctggacaaagccctgggccagaagtag
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