Eptesicus fuscus (big brown bat): 103305553 Help Entry 103305553         CDS       T09083                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism efus  Eptesicus fuscus (big brown bat) Pathway efus00230   Purine metabolism efus01100   Metabolic pathways efus01522   Endocrine resistance efus04015   Rap1 signaling pathway efus04020   Calcium signaling pathway efus04022   cGMP-PKG signaling pathway efus04024   cAMP signaling pathway efus04062   Chemokine signaling pathway efus04072   Phospholipase D signaling pathway efus04081   Hormone signaling efus04082   Neuroactive ligand signaling efus04114   Oocyte meiosis efus04211   Longevity regulating pathway efus04213   Longevity regulating pathway - multiple species efus04261   Adrenergic signaling in cardiomyocytes efus04270   Vascular smooth muscle contraction efus04371   Apelin signaling pathway efus04540   Gap junction efus04611   Platelet activation efus04713   Circadian entrainment efus04714   Thermogenesis efus04723   Retrograde endocannabinoid signaling efus04724   Glutamatergic synapse efus04725   Cholinergic synapse efus04727   GABAergic synapse efus04740   Olfactory transduction efus04750   Inflammatory mediator regulation of TRP channels efus04911   Insulin secretion efus04912   GnRH signaling pathway efus04913   Ovarian steroidogenesis efus04914   Progesterone-mediated oocyte maturation efus04915   Estrogen signaling pathway efus04916   Melanogenesis efus04918   Thyroid hormone synthesis efus04921   Oxytocin signaling pathway efus04923   Regulation of lipolysis in adipocytes efus04925   Aldosterone synthesis and secretion efus04926   Relaxin signaling pathway efus04927   Cortisol synthesis and secretion efus04928   Parathyroid hormone synthesis, secretion and action efus04934   Cushing syndrome efus04935   Growth hormone synthesis, secretion and action efus04962   Vasopressin-regulated water reabsorption efus04970   Salivary secretion efus04971   Gastric acid secretion efus04972   Pancreatic secretion efus04976   Bile secretion efus05032   Morphine addiction efus05163   Human cytomegalovirus infection efus05166   Human T-cell leukemia virus 1 infection efus05200   Pathways in cancer efus05207   Chemical carcinogenesis - receptor activation efus05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:efus00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103305553 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103305553 (ADCY3)    04371 Apelin signaling pathway     103305553 (ADCY3)    04020 Calcium signaling pathway     103305553 (ADCY3)    04072 Phospholipase D signaling pathway     103305553 (ADCY3)    04024 cAMP signaling pathway     103305553 (ADCY3)    04022 cGMP-PKG signaling pathway     103305553 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     103305553 (ADCY3)    04081 Hormone signaling     103305553 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103305553 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     103305553 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103305553 (ADCY3)    04062 Chemokine signaling pathway     103305553 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     103305553 (ADCY3)    04923 Regulation of lipolysis in adipocytes     103305553 (ADCY3)    04912 GnRH signaling pathway     103305553 (ADCY3)    04913 Ovarian steroidogenesis     103305553 (ADCY3)    04915 Estrogen signaling pathway     103305553 (ADCY3)    04914 Progesterone-mediated oocyte maturation     103305553 (ADCY3)    04921 Oxytocin signaling pathway     103305553 (ADCY3)    04926 Relaxin signaling pathway     103305553 (ADCY3)    04935 Growth hormone synthesis, secretion and action     103305553 (ADCY3)    04918 Thyroid hormone synthesis     103305553 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     103305553 (ADCY3)    04916 Melanogenesis     103305553 (ADCY3)    04925 Aldosterone synthesis and secretion     103305553 (ADCY3)    04927 Cortisol synthesis and secretion     103305553 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103305553 (ADCY3)    04270 Vascular smooth muscle contraction     103305553 (ADCY3)   09154 Digestive system    04970 Salivary secretion     103305553 (ADCY3)    04971 Gastric acid secretion     103305553 (ADCY3)    04972 Pancreatic secretion     103305553 (ADCY3)    04976 Bile secretion     103305553 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     103305553 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     103305553 (ADCY3)    04727 GABAergic synapse     103305553 (ADCY3)    04725 Cholinergic synapse     103305553 (ADCY3)    04723 Retrograde endocannabinoid signaling     103305553 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     103305553 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     103305553 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     103305553 (ADCY3)    04213 Longevity regulating pathway - multiple species     103305553 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     103305553 (ADCY3)    04714 Thermogenesis     103305553 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103305553 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     103305553 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103305553 (ADCY3)    05163 Human cytomegalovirus infection     103305553 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     103305553 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103305553 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103305553 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103305553 (ADCY3) Enzymes [BR:efus01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103305553 (ADCY3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  103305553 NCBI-ProteinID:  XP_054583895 LinkDB All DBs Position 16:complement(10406699..10460224) Genome browser AA seq 1145 aa AA seqDB search MPRTQGFSEPEPSAEHSAEYSASLPSDPDRRRGRAHEISVRSSGSCLCLPRFLRLTFVPA SLESLYQTYFRRQRHETLLVLVVFAALFGCYVVAMCAAVFAPDRLAPLAVAGVGLLLDIV LFALCRQGLLPSRVARKVVPYLLWLLITAQVFSYLGLGFPGAHAAGDTVGWLAFFVFSFF ITLPLGLGPIVVISVVSCVAHTLVLGVTVAQQQQDRLKGMQLLREILANVFLYLCAIVVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSTCSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGEGGSRCD YLEEKGIETYLIIASKPEVKKTASQNGLNSSALPNGAPASSKPSSPALIETKESNGSVHT SGSTSEENEEQDAQADNPSFPNPHRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMDPELETRYSVEKEKQSGAAFSCSCVVLLCAALVEIVIDPWLMTN YVTFVVGELLLLVLTVCSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYMGPNNGTSGMATEDGCMENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLITGAVAVINLCAWRPIFDEYDRRRFQEPGFPLVALEKMQILSTPGLNGTGRLPLVPSK YTMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPDH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEERSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAFPNGSSVTLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggacccagggcttctccgagcccgagccctcggccgagcactccgccgagtac tcggccagcctgccctccgacccggaccgccggcggggccgggcgcacgagatctcggtg cggagctcggggtcctgcctctgcctgccccgcttcctgcggctgaccttcgtgcccgcg tccctggagagcctgtaccagacctacttccggaggcagcgccacgagaccctgctggtg ctggtggtgttcgccgcgctcttcggctgctacgtggtggccatgtgcgccgccgtcttc gccccggacaggctggcccccctcgccgtggccggcgtcgggctgctgctggacatcgtc ctcttcgcgctgtgcagacaggggctgctccccagccgggtggcccgcaaggtggtgccc tacctgctgtggctgctgatcacggcgcaggtcttctcctacctgggcctcggcttcccc ggcgcccacgcggccggcgacacggtgggctggctggccttcttcgtcttctccttcttc atcacgctgcccctcggcctcggccccatcgtcgtcatctcggtggtctcctgtgtggcg cacacgctcgttttgggggtcaccgtggcccagcagcagcaggacaggctgaaggggatg cagttgctgagagagatcctggccaacgtcttcctctacctgtgcgccatcgtcgtgggc atcatgtcctactacatggcggaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaacctgatgctc tccatcctgcccaagcacgtggctgacgagatgctgaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaatgtcagcatc ctcttcgcggacatcgtgggcttcacccagctgtcttccacctgcagcgcccaggagctg gtgaagctgctcaacgagctcttcgcccgcttcgacaagctggcggccaaataccaccag ctgcggattaagatcctgggcgactgttactactgcatctgcggcctgcctgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtac gtgcgggagaagacaaagaccggggtggacatgcgtgtgggggtgcacacgggcactgtg ctggggggcgtcctgggccagaagcgctggcagtatgacgtgtggtctaccgatgtcact gtggccaacaagatggaggctggcggcatccccgggcgcgtgcacatctctcagagcacc ctggactgcctgaaaggggagttcgacgtggagcccggcgaggggggcagccgctgcgat tacctagaggagaagggcattgaaacctacctcatcattgcgtccaagccagaggtgaag aaaaccgcctcccaaaacggcctcaacagctcggccctgcccaacggcgcgcccgcgtcc tcaaagcccagctcccctgccctcatcgagaccaaggagtccaatgggagtgtccacacc agcggctccacgtcggaggagaacgaggagcaggatgcccaggccgacaacccctcgttc cccaaccctcaccggaggctgcgccttcaggacctggctgatcgggtggtggacgcctct gaggacgagcacgagctcaaccagctcctcaacgaggccctgctcgagcgggagtccgcg caggtagtgaagaagagaaacaccttcctcctgtccatgcggttcatggaccccgagctg gaaacccgctactcggtggagaaggaaaagcagagcggggccgccttcagctgctcctgc gtcgtgctgctctgcgcggccctggtggagatcgtcatcgacccctggctgatgaccaac tatgtgacctttgtggttggggagctcctgcttctggtcctgacggtctgctcgctggct gccatctttccccgggcctttcctaagaagcttgtggccttctcgacgtggattgaccgg acacgctgggccaggaacacctgggccatgttagccatcttcattctggttatggcaaat gtcgtggacatgctgagctgcctgcagtactacatgggacccaacaatggcacctcaggg atggcgacagaggatggctgcatggagaaccccaagtattacaactatgtcgccgtgctg tccctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcaccctcatg ctgcttatcacgggcgctgtggctgtcatcaacctctgtgcctggcgccccatctttgat gagtatgaccgcagacgtttccaggaacccggctttcctctggtcgccttagagaagatg cagatactctccaccccagggctcaatggcactggcaggctgcccttggtgccttctaag tacacgatgacagtgatgatcttcgtcatgatgctgagcttctactacttctcccgccac gtggaaaaactcgcacggacactgttcttgtggaagattgaggtccatgaccagaaggaa cgtgtctacgagatgcgacgctggaatgaggccctggtcaccaacatgttgcccgatcat gtggcacgccatttcctggggtccaagaagagagatgaggagctgtatagccagtcttat gatgagattggagtcatgtttgcctccctgcccaactttgctgacttctacacagaggag agcatcaataatggtggcattgagtgtctgcgcttcctcaatgagatcatctcagatttt gactctcttctagacaatcccaaattccgggtcatcaccaagatcaaaaccattggcagt acctatatggcagcttcaggagtcaccccagatgtcaacaccaacggctttaccagctcc agcaaggaggaaaggtcagacaaggagcgctggcagcacctggccgatctggccgacttt gcactggccatgaaggatacgctgaccaacatcaacaaccagtccttcaacaacttcatg ctgcgcataggcatgaacaaaggaggggtcctggctggggtcatcggagcccggaaaccg cactacgacatctggggcaatacagtcaatgtcgccagcaggatggagtccacaggggtc atgggtaacattcaggtggtagaagaaacacaagccatccttcgggagtacggcttccgc tttgtgagacgggggcccatctttgtgaaagggaagggggagctgctaacctttttcttg aaggggcgtgataagccagccgccttcccgaatggctcctctgtgactctgccccaccag gtagtagacaactcctga

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