Duffyella gerundensis: EM595_0667
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Entry
EM595_0667 CDS
T04258
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ege
Duffyella gerundensis
Pathway
ege00260
Glycine, serine and threonine metabolism
ege00261
Monobactam biosynthesis
ege00270
Cysteine and methionine metabolism
ege00300
Lysine biosynthesis
ege01100
Metabolic pathways
ege01110
Biosynthesis of secondary metabolites
ege01120
Microbial metabolism in diverse environments
ege01230
Biosynthesis of amino acids
Module
ege_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ege_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
ege_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ege00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
EM595_0667 (thrA)
00270 Cysteine and methionine metabolism
EM595_0667 (thrA)
00300 Lysine biosynthesis
EM595_0667 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
EM595_0667 (thrA)
Enzymes [BR:
ege01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
EM595_0667 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
EM595_0667 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-ProteinID:
CUU22903
UniProt:
A0A0U5L354
LinkDB
All DBs
Position
1:743219..745681
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNAKQGQVATVLSAPAKITNHLVAMIEKTISGQDA
QPNISDAERIFSELLQGLAERQPGFEYDRLHTIIELEFAQLKQMLHGVSLLGQCPDSINA
AIICRGEKLSIAIMEALLQARGHQVSVIDPVEKLLAVGHYLESTVDIAESTRRIAASHIP
VTNMILMAGFTAGNERGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTANPQAPGTLIGGQGG
DTENPVKGITNLNNMAMFNVSGPGMKGMVGMAARVFAAMSRSGISVVLITQSSSEYSISF
CVPQSDLLRARRVLDEEFYLELKDGLLDPLEVMEQLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDVTTGVRVVHQMLFNTDQVIEVFVVGVGGVGSAL
LDQLQRQQAWLKQKHIDLRVCGIANSKALLTNVHGIDLSNWKTALQSAKEPFNTAHLTRL
VKEYHLLNPVIVDCTSSQTVADLYADFLGNGFHVVTPNKKANTSSWDYYLQMRAAAEKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELIKFSGILSGSLSFIFGKLDEGVSLSAATALA
REMGFTEPDPRDDLSGMDVARKLLILAREAGHQLELTDIEIEPILPAELAALPDAESFMQ
RLPELDDAFASRVAHASAEGKVLRFVGVIEEGGVCKVKIDAVDGNDPLYKVKNGENALAF
YSRYYQPIPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGI
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaattcggcggaacctcagttgccaacgcagagcggtttttacgcgtt
gccgatattctggaaagcaacgccaaacagggacaggtcgccaccgtgctctctgcgcca
gcaaaaatcaccaatcacctggtggcgatgatcgaaaaaaccatcagcgggcaggatgct
cagccgaatatcagcgatgcggagcgcattttctctgaactgcttcaggggctggcagag
aggcagcccggttttgaatatgaccgactccataccatcatcgaactggaattcgcccag
ttaaaacagatgctgcatggcgtcagcctgttggggcaatgcccggacagcatcaacgct
gccattatttgccgcggtgaaaaactctctattgccattatggaagcgctgctgcaggcg
cgtggtcaccaggtgagcgtgatcgatccggtagaaaagctgctggccgtggggcactat
ctggaatcaaccgtagatattgctgaatccacccgtcgcatcgccgccagccatattccc
gtcacgaacatgatcctgatggcgggctttaccgccggaaacgagcgcggcgagctggtg
gtgttgggccgtaacggttctgactattccgccgctgtgctggcagcctgcctgcgcgcc
gactgctgcgaaatttggaccgacgttgatggcgtttatacctgcgatccgcgccaggtg
cccgatgcgcgcctgctgaaatcgatgtcctatcaggaagcgatggagctctcctatttt
ggtgccaaggtgttgcatccgcgcactatcgcgcctatcgcccagtttcaaattccgtgc
ctgatcaagaacaccgctaatccacaggcgccaggcacgctaatcggcggccagggcggc
gacaccgaaaatccggtgaagggcatcaccaacctgaataatatggcgatgttcaacgtc
tctggtcccggcatgaaaggcatggtcggcatggctgcgcgcgtgtttgctgccatgtcg
cgctccggcatttcggtggtgctgattacccaatcctcttctgaatacagcatcagcttc
tgcgtgccgcaaagcgatctgctgcgtgcgcgccgcgtgctggatgaggagttttatctt
gagttgaaagatggcctgctggatccgctggaagtgatggagcagctggcgatcatctcg
gtagtcggcgacggcatgcgcacgctacgtggcatctcagctaaattctttgcggcgctg
gcgcgcgccaacatcaacattgttgccattgcgcagggttcgtctgagcgctcaatttcg
gtggtggtcagcaacgacgacgtcaccaccggcgtgcgcgtggtgcaccagatgttgttc
aacaccgatcaggtgattgaggtatttgtggttggcgttggcggcgttggtagcgcgctg
ctcgatcagctgcagcgccagcaggcttggctcaagcagaagcatatcgatctgcgagtg
tgcggcatcgcgaattcaaaagcgctgctgaccaacgtgcacggcatcgatttaagcaac
tggaaaaccgcgctgcagagcgctaaagagccgttcaacaccgcgcatctgacgcgtctg
gtgaaagagtatcacctgctgaacccggtgattgttgactgtacgtccagccagacggtg
gccgatctctacgcggattttctcggcaacggtttccacgtggtaacgccgaacaaaaag
gccaacacctcaagctgggattactacctgcaaatgcgcgcagcggcagaaaaatcgcgc
cgcaagttcctctatgacaccaacgtcggtgccggcctgccggtgattgaaaacctgcaa
aacctgcttaacgcgggcgatgagctgatcaagttctccggcattctctccggctcgctg
tcgtttatttttggcaagcttgatgagggcgtttcactctcggccgctaccgcgctggcg
cgtgaaatgggctttaccgagcccgatccgcgtgacgatctttccggcatggatgtggcg
cgcaagctgctgattctggcgcgtgaagcgggacaccagctggagctcaccgatattgaa
attgagccgatcctgcctgccgaattggccgcactgccggacgccgagagctttatgcag
cgcctaccggagctggatgacgcctttgccagccgcgtggctcacgccagtgccgagggt
aaagtgctgcgctttgtgggtgtgattgaagagggcggcgtttgcaaagtgaagattgat
gccgtggacggtaacgatccgctctataaagtcaaaaacggcgagaatgcgctggcgttt
tacagccgctattatcagccgattccactggtgctgcgcggttatggcgcgggcaacgat
gttacggccgcaggcgtatttgccgatctgctgcgtacgctctcctggaagttggggatt
taa
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