KEGG   Echinococcus granulosus (hydatid tapeworm): EGR_09764
Entry
EGR_09764         CDS       T05553                                 
Name
(RefSeq) Dihydropyrimidine dehydrogenase [NADP+]
  KO
K00207  dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]
Organism
egl  Echinococcus granulosus (hydatid tapeworm)
Pathway
egl00240  Pyrimidine metabolism
egl00410  beta-Alanine metabolism
egl00770  Pantothenate and CoA biosynthesis
egl00983  Drug metabolism - other enzymes
egl01100  Metabolic pathways
Module
egl_M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
Brite
KEGG Orthology (KO) [BR:egl00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    EGR_09764
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    EGR_09764
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    EGR_09764
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    EGR_09764
Enzymes [BR:egl01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.2  dihydropyrimidine dehydrogenase (NADP+)
     EGR_09764
SSDB
Motif
Pfam: DHO_dh Fer4_20 Fer4_21 Pyr_redox_2 Fer4_7 Pyr_redox_3 Pyr_redox NAD_binding_8 Fer4_10 Fer4_6 Fer4_9 Fer4 NAD_binding_7 FAD_oxidored
Other DBs
NCBI-GeneID: 36345479
NCBI-ProteinID: XP_024346583
UniProt: U6J690
LinkDB
Position
Unknown
AA seq 1201 aa
MHDESHNVRAMTIFHEGLVIQEEKQRQNPWYLLRAEPHLSARRSETETLNTHTIHRSFNE
PISIRCAAIGCDANDEIKWVCSGKGACLFEEEWWQGWMYRQAQRVLGRQVELVRAGRRSL
ACPSVGCGGAGGAGGGGCGVRGGRKCFSSLNHEEVSRHSAEIEAVLRLQPKVPTAATVKP
TTEIRQEKRNWKRNADKNDSAMLPLHYDFSDAKATTLGERGALREAARCLKCADAPCQHS
CPTQLDVKAFVGSIGKKNYYGAAKAILSDNPNGLTCGMVCPTSDLCVGACNLTATEEGAI
NIGGLQQFAVEMFANMNVPQIVDPAIVARTAGDAQYDTKIALVGCGPASISCATFLARLG
YRNVHIFERDERPGGLSTMEIPQFRLPGAAVAFELQLLRDLGVRIFTGRPFSATAAEASE
CGTTPRGVTLASLRAAGYKAIFLGFGLPNAHSTGVFAGLTSQQGFLTSKDFLPCVSAASK
GCLGCENAHLPDLKGKRVVVLGAGDTAFDCATSALRCGASRVTVSFRKSFTTINPVPEEM
ELAWQEKCEFLPNLVPQEVHLGAGGQISELSLVRRERDDDGSWYTDPEQVVKLKVDVIIT
AYGAELNDADVVSAMEGVKLAPSGFSAGLPVVDAKTMRTNLPDVWCGGDLTGFAHTSVEA
TNDGKTAAWSIHSTLLGEADLPMRLPRFSTPIDAVDVSVDVCGVKFENPFGLASAPPTTS
SAMIRRAFEAGWGFAVTKTFGLDKDLVTNVSPRIVRGPTGGHLYGPDQSGFCNIELISEK
TAAYWVESIKELKRDFPEKRVIASIMAKFDEADWREITERTLRAGPDALELNLSCPHGMG
ERGMGMACGQDPRLVREICKWVKSVGGAGTPVFAKLTPNVSDILEIAQAAQDGGADGVTA
INTVSGIMHFDSDSSAWPRVGKERRTTYGGLSGNLVRPMALRAVSWIAKKLPGFPILATG
GIDSAEAGMQFLQAGASILQVSSAIQNQDFTIIEDMVTGLKAGLYLDGREEHWNFQSADV
GERQQQGKPVKGVETLNGQYLPHFGLARAVRAAHWARECWESAGGVSVALAERHLDRWLC
RPTPTSSTPTVADIIGRAVDKIGMYNELSNKEHVVALVDEELCINCGKCYMTCNDTGYQA
IDFDAKTHLPVVREADCTGCTLCFSVCPVPDCIRMVERKTLYVPKRGIPPASASAPAPPV
S
NT seq 3606 nt   +upstreamnt  +downstreamnt
atgcacgatgaaagccacaatgtgcgagccatgaccatctttcacgaaggcctggttatt
caggaagaaaaacaacgccaaaacccgtggtacctcctccgagcggagccgcacctgtcg
gcacgacgaagcgagacggaaaccctcaacacacacacaatccaccgatcgttcaatgag
ccaatcagcatccggtgcgccgccattggctgcgacgcgaatgatgaaataaaatgggtg
tgcagcggcaagggtgcatgtttattcgaagaggagtggtggcaggggtggatgtatcgc
caagcacagcgagtactaggtagacaagtggagttggtgcgtgcgggacgacggtcactc
gcctgtccgagcgtgggatgtggtggtgctggtggtgccggtggtggtggatgcggtgtc
cgcggtggtagaaagtgcttctcctcgttgaatcacgaggaggtgagtcggcactcggcg
gagattgaggcggtgctgcgtctgcagcccaaagtacccaccgccgctactgtcaaaccc
acgactgagattcgtcaggagaagaggaattggaagcgcaacgcggacaagaacgactcg
gcaatgctgccactgcactatgacttttcggacgcgaaagcgacgacgttgggtgagcgt
ggagcactgcgtgaggcggcgcggtgtctgaagtgcgcggatgcgccatgtcagcacagt
tgtcccacacagctggacgtgaaggcgtttgtggggagcattgggaagaagaactactac
ggtgccgcgaaggccatcctgtcggacaatccgaacggtctgacctgtggcatggtgtgt
cctaccagtgacctctgtgtcggcgcctgtaacctaaccgctacggaggaaggggccatc
aacataggtggactgcagcagttcgctgtggagatgtttgccaacatgaatgtgcctcag
atagtggacccggcgatagtggcgaggactgcgggtgatgcgcagtacgacacgaagatc
gcgctggtaggctgtggaccggcgagtatctcatgcgcgacgttcctggcgcggttgggc
taccgcaatgtgcacatcttcgagcgtgatgagcgacccggtggactgagtacaatggag
ataccgcagtttcgtctgcccggagccgctgtcgccttcgagctgcagttgttgcgtgac
ctcggtgtgcgcatatttacggggcgtcccttctctgccactgcagctgaggcttccgag
tgtggcaccacaccccgaggtgtgacattggccagtctgcgtgctgcgggttacaaggct
atattcctggggtttgggctgccgaacgcacactcgacaggggtgtttgctggtctgacg
tcgcagcagggcttcctcacctcgaaggactttctgccttgcgtatccgcagcttcgaag
ggctgtttggggtgtgaaaacgcacatttgccggatctgaaagggaagcgtgtggtggtg
ctgggcgctggtgacactgccttcgactgtgccacgtcggcactgcgctgtggcgcctcg
cgtgtgaccgtctccttccgcaagagcttcaccaccatcaatcccgtgccggaggagatg
gagctggcgtggcaggagaagtgtgagttcttgcccaacctcgtgccgcaggaagtgcac
ctgggtgctggcgggcagataagtgagctgagtttagtgcggcgcgagcgcgacgatgac
ggctcgtggtacacggatcctgaacaggtggtgaaattgaaggtggacgtcattatcact
gcctatggagcggagttgaatgacgcggatgtggtgagtgcgatggagggtgtgaagctg
gcacccagtggcttctcggcgggtctgcccgtggtagatgcgaagacgatgcgtaccaat
ctgcccgacgtgtggtgtggtggtgacctgaccggcttcgcgcacaccagtgtggaggcg
acgaatgacggtaagacggcggcgtggagcatccacagtactctgttgggtgaggcggac
ttgccgatgaggttgccacgcttcagcacacccatcgatgcggtggatgtgtcggtggat
gtgtgtggcgtgaagttcgagaatccgtttggtctggcctcggcgccaccgacgacgtcg
agtgcgatgatccggcgtgccttcgaggcaggttgggggtttgcggtgacaaagaccttt
ggtctggacaaggacctggtgacgaatgtgtcgccgcgcatcgtgcgcggtcccacggga
ggtcatctgtacggaccagaccagtcgggtttctgcaacatagagttgataagcgagaag
acggcggcgtactgggtagagagcataaaggagctgaagcgtgactttccggagaagagg
gtgatagcgagcataatggcgaagttcgacgaggcggactggcgagaaatcacggagcgc
acgctgagggcaggaccggacgcactggagttgaatttgtcgtgtccgcacgggatggga
gagaggggcatggggatggcgtgcggtcaggatccgcggttggtgcgcgagatctgcaag
tgggtgaagagtgtggggggagcggggacaccggtgtttgcgaagctgacgcccaacgtg
agtgacattctggaaatcgcacaggctgcacaggatggcggagcggacggtgtgaccgcg
atcaacacggtgtcggggataatgcacttcgacagtgactcctcagcctggccacgtgtt
ggtaaggagcggcgcacaacgtacggcggtttgtcgggcaatttggtgcgaccaatggcg
ttgcgtgcggtgagctggatcgcgaagaagttgccgggcttccctatcctcgccacaggt
ggtatcgactcggcggaagcgggcatgcagttcttacaggctggtgcctccattttgcag
gtgtcgagtgccattcagaatcaggacttcacaatcatcgaggacatggtgacaggcctc
aaagctggtctgtacttggatggacgtgaagagcactggaacttccagagtgcggatgtg
ggtgagcgacaacagcaaggcaagccagtgaagggggtggagacactgaatggccagtac
ctgccgcacttcggactggcgcgggcagtgcgtgctgcacattgggcgcgggagtgctgg
gagtcggcaggcggcgtctccgtggctctggctgagcgtcatctggaccgttggctctgt
cgccctacaccaacctcttcaactccaaccgttgctgacataattgggcgggccgtggac
aagatcggcatgtacaatgagctgagcaacaaggagcatgtggtggcactggtggacgaa
gagttgtgcatcaactgcggcaagtgctacatgacgtgcaacgacacaggctaccaggcg
atcgacttcgacgcaaagacacacctgccggtggtgcgcgaggccgactgtacgggctgc
acgctctgcttctcggtgtgccctgtgcccgactgcattcgcatggtggagcgcaagacg
ctgtacgtgccgaagcgtggcatccctccggcttctgcatccgcacccgcaccccctgtc
tcctaa

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