Enterococcus hirae: EHR_03910
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Entry
EHR_03910 CDS
T02160
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ehr
Enterococcus hirae
Pathway
ehr00300
Lysine biosynthesis
ehr00550
Peptidoglycan biosynthesis
ehr01100
Metabolic pathways
ehr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ehr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EHR_03910
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EHR_03910
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EHR_03910
Enzymes [BR:
ehr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EHR_03910
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF3323
Motif
Other DBs
NCBI-ProteinID:
AFM69752
UniProt:
I6SWJ2
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All DBs
Position
complement(738867..740219)
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AA seq
450 aa
AA seq
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MKLTVQEIAQAVGSVMNDLTEITGVEFDSRKIEKGGLFVPLKGARDGHEFIQQAMDNGAV
ATFWSLEATKAPSGIRVILVDDPLKAMQDLAKYYLAKVGAEVVAITGSNGKTTTKDLTAS
VLAQKYKTYKTQGNYNNNIGLPYTILHMPMDTEKIVLEMGMDHAREITELSLIARPKVAA
ITMIGEAHIENLGSRAGIAQAKMEIVDGLREDGLLIIPEEEPLLKPLTESLTQKIETFGL
NTGELQAEVTSEEKTATHFIVNDESFMIPLPGSYNVTNALIAYAVGQFFGLPTEAIRLGL
ASVTVTQNRTEWLSAGNGAGILSDVYNANPTAMGLVLDTFANLPTKGRRLAVLADMLELG
PDALKMHASMAEHLDPADFAGVYLYGPQMKALYEKLNEKYPDLYVQYFETDKEQLIATVK
EEIRPEDSIVLKGSNGMGLIDVVKQLQGMK
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atgaaactaacagtacaagaaatcgctcaagctgtaggaagcgtaatgaatgatttaacg
gaaatcacaggtgtggagttcgatagtcgcaagattgaaaaaggtgggttgttcgtgccg
ctaaaaggagcaagagatggacacgaatttattcaacaagccatggataatggagcggtt
gctactttttggagtctggaagcgaccaaagcacctagtgggattcgagtgattcttgtg
gatgatccactaaaagcaatgcaagatctggcgaagtactacctagcgaaagttggggct
gaagtggtggcaattacgggaagtaatgggaaaacaacgacaaaagatttgactgcttca
gttttagctcaaaagtacaaaacctataaaacacaaggaaattacaacaataatattggc
ttgccttatacgattttgcacatgccgatggataccgaaaaaatcgttttagaaatgggg
atggatcatgccagagagatcactgagctttctttgattgcccgacctaaagtagcggct
attacgatgattggtgaagcacatattgaaaaccttggctcacgagcaggaatcgcgcaa
gcaaaaatggagattgttgatggtttgagagaagatgggctgttgattatcccagaagaa
gaaccattattgaaacctttgactgaaagtttgactcaaaaaattgaaacgtttggatta
aatacaggggagctacaggcggaggtaacgagtgaagagaaaacagccacacattttatc
gtcaatgatgaatcgttcatgattcctcttcctggaagttataatgtcaccaatgcgttg
attgcttatgctgttgggcaattttttggtctgccaacggaagccatccgtctaggttta
gcaagtgtcacagtgacgcaaaatcgtacggagtggctaagtgctggaaatggtgcgggg
attctaagtgatgtctataatgcgaatcctacagcaatgggattggtcttagatactttt
gccaacttaccaacaaaagggagaagacttgctgtacttgcggacatgctggaattagga
ccagatgctttgaagatgcacgcaagtatggctgaacatcttgatccagctgattttgcg
ggagtctatttatatgggccccaaatgaaagcattatatgaaaagttgaacgaaaagtat
ccagatttatacgtacaatattttgaaacagataaagaacaactcattgcaacggtgaaa
gaagaaatacgtccggaagatagcatcgttttaaaaggaagcaatggaatgggattgatt
gatgtcgttaaacaattgcaaggaatgaaataa
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