Enterococcus hirae: EHR_04295
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Entry
EHR_04295 CDS
T02160
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
ehr
Enterococcus hirae
Pathway
ehr00270
Cysteine and methionine metabolism
ehr00480
Glutathione metabolism
ehr01100
Metabolic pathways
ehr01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ehr00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
EHR_04295
09106 Metabolism of other amino acids
00480 Glutathione metabolism
EHR_04295
Enzymes [BR:
ehr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
EHR_04295
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
GARS_A
RimK
ATPgrasp_ST
R2K_3
R2K_2
Dala_Dala_lig_C
Motif
Other DBs
NCBI-ProteinID:
AFM69829
UniProt:
I6T9C1
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Position
complement(814757..817036)
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AA seq
759 aa
AA seq
DB search
MNFKQLLKHPSSRPFIDQARFGVEREGQRVNLTGDLTRTDHPSVFGDRTFHPYIQTDFSE
TQIELITPVTDSIHELFQYMSAIYDVAARSIPENEMIWPLSMPPALPAKDEDIMIAKLAN
FEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDDLLRSLFVQQTEFSEFAAFKTELYLKTA
RNFLRYRWLITYFYGASPLSEANYFIDKPAPNEPVRSIRNSSYGYTNHPNVKVSYASMEQ
YLFDIEKMVEEGKLSEEKEFYTPLRFRGGKRVADLAKTGVRYIELRNIDLNPNARLGIDQ
EQVRFLQLFLTYMLWTEEKEAADQWVEEGTRKNEIVSLEHPLNQTEFIEEGRYLLTDMKK
MALELEQLEALPLIEKMLEELERPSETLAGTIYQAAKESSQHQFATSLGLSYYQKAHERP
YQLAGFREMELSTQILLFDAIQKGIEVKVIDESDQFLRLQHHDHIEYVKNANMTSKDSYI
VPLIMENKTVTKKVLREAGYRVPNGAEFTTMEEAVKAYPRFANKAFVIKPKSTNYGLGIT
IFKEGADLADYQAGLAIAFSEDRSILVEEFMPGTEYRFFVIDGKVKAIMLRKPANVVGDG
QRTVAELVAEKNLDPLRGTNHRAPLELIHLGELEQLMLKEQGLTVSSVPQKDQVVYLREN
SNISTGGDSIDVTDEFSESYKQIAVSAVEALGAKISGIDLIIPDKEVAPENSATAYGIIE
ANFNPAMHMHVYPFAGKGRRLTLDVLNLLYPELNILTQN
NT seq
2280 nt
NT seq
+upstream
nt +downstream
nt
atgaattttaaacaattactaaaacatcctagttcacgtccatttatcgatcaagcacgt
tttggtgtggaacgagaaggacagcgagtgaaccttacaggagatctaacacgtactgat
catccaagtgtttttggcgatcgtacgtttcatccatatatacagacagactttagtgaa
acacaaattgaattaattacaccagtcaccgattcgatccatgagcttttccaatatatg
tcagccatttatgatgttgctgctcgctcaattcctgaaaatgaaatgatctggccttta
agtatgccaccagcattgccagcaaaagatgaagacatcatgattgcaaaattagcaaat
tttgaagatgtgttatatcgccgctatttagctaaagaatatgggaaaagaaagcaaatg
gttagtggtatccattttaattttgaatttggagatgatttgcttcgatcgttgtttgtg
caacaaacagagttttcggagtttgctgcttttaaaacagagctatatttgaaaactgcg
cgcaattttctgcgctatcggtggttgattacctatttttatggggcatcaccattaagt
gaagcaaactatttcattgataaaccagctcctaatgagccagttcgaagtattcggaat
agttcgtatggttatacgaatcatccaaatgtcaaagtttcgtatgcttcaatggagcaa
tatttgttcgacattgaaaagatggttgaagaaggaaaactatcagaagaaaaagaattt
tatacgccacttcgttttcgtggtggtaaacgggtagcagatttagctaaaacgggtgtg
cgttatatcgaattaagaaatatcgatttaaatcccaatgcacgtttaggaattgatcaa
gaacaagttcgtttcttacagttatttttaacttatatgttatggacggaagaaaaagaa
gcagctgatcaatgggtagaagaaggaactagaaaaaatgaaatcgtctctcttgaacat
cctctaaatcaaaccgagtttatcgaggaaggccgttatcttttaactgatatgaagaaa
atggcgctcgaacttgagcaactagaggcactaccattgattgaaaaaatgttagaagaa
ctggaacgtccaagtgaaacactagcaggaacaatctatcaagcagcaaaagaaagtagt
caacatcagtttgctacctctttgggtctttcttactatcaaaaagcgcatgaacgtccg
tatcaactcgcaggatttagagagatggagttgtctacgcaaatcttgttatttgatgcg
atccaaaaaggtattgaagtgaaagtgattgacgaatcggatcaatttttgcggttacag
catcacgatcatattgagtacgtgaaaaatgcaaatatgacaagtaaagatagctatatc
gttcccttgatcatggaaaataaaacggtcactaaaaaagtcttgagagaagccggctat
cgtgtgccaaacggagccgagtttacgacaatggaggaagcagtcaaagcctatccaaga
ttcgcaaacaaagcatttgtcattaaacctaaatcaacgaactatggactaggcatcacg
atttttaaagaaggtgctgatttagctgactatcaagcaggacttgcgattgcctttagc
gaagatcgttcgattttagtagaagaatttatgccaggcacggaatatcgcttctttgtg
attgatggcaaagtcaaagcaatcatgcttcgtaaacctgctaatgtcgttggagatgga
caacgtacagttgctgaattggtcgctgaaaagaatcttgatcctttaagaggcacaaac
catcgagcacctttagagctaattcatttaggagaattagagcaactgatgttaaaagaa
caagggcttaccgtttcttctgttccccagaaagatcaggttgtttatctacgagaaaat
tctaatattagtacaggtggcgattcgattgatgtcacagacgaattttctgaaagttat
aagcagatagctgtttctgcagttgaagctttaggcgcaaaaattagtggaatcgatttg
attattccggacaaagaggtagcaccggaaaacagcgctactgcttatgggattatcgaa
gctaactttaatccagcgatgcatatgcacgtgtacccatttgcaggtaaagggagaaga
ttgactttagacgtgttgaatttattgtatcctgaacttaatatcctgactcaaaattaa
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