Eurypyga helias (sunbittern): 104510089 Help Entry 104510089         CDS       T08356                                  Symbol UBR4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism ehs  Eurypyga helias (sunbittern) Brite KEGG Orthology (KO) [BR:ehs00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:ehs04121]     104510089 (UBR4) Enzymes [BR:ehs01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      104510089 (UBR4) Ubiquitin system [BR:ehs04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     104510089 (UBR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 UBR4 zf-UBR TAL_FSA Motif Other DBs NCBI-GeneID:  104510089 NCBI-ProteinID:  XP_010150534 LinkDB All DBs Position Unknown AA seq 4236 aa AA seqDB search PPPPPLESSPRVKSPNKQTAGENGNILASRKDPELFLSLASNILNFITSSMLNSRNNFIR NYLSVSLSEQHMATLAGIIKEVDKDGLKGTSDEEFAAALYHFNHSLVTSDLQSPALQNTL LQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKATAQGDPDVPECLKVWERFVGTLR QNALQGTLPSDTEDLNVEHLQLLLLIFHNFSERGRRSIMMLCIQTIVELTANMDTQQCSV PLIVARLLLVFDYLLHQFSKAPMYLFEQVQYNLLTPPIGWVSGSQDSSRRTSVPLYHGFK EVEENWTKHCSSDAVPQPRFYCILSLEASEDDLNRLDGMVCEVLFSRTMKYDELYTALTS LLAAGSQFDTLRRKENKNVTALEACALQYYFLILWRILGILPPSKNYMNQLATNSPEMSE CDILHTLRWSSRLRITSYVTWIKDHLTKQGMKADHAASLVELASSKCSSVKYDVEIAEEY FARQISSFCGVDCTTILQLHEVPSLQSIYTLDAAISKIQVSLDEHFSKLAAETDPHKSSE ITKNLLPATLQLIDTYATFTRSYLLRSLSEEGSPENKPSEEKLRGYAAVLAIGSSRCKSN TLGPTLVQNLPSAVQTLCESWNNIHTNEFPNIGSWRNAFANDTIPAESYISAVQAAHLGT LCSQSLPLAASLKHTLLSLVRLTGDLIVWSDDLNPPQVIHSLLPLLLETSTESVAEISSN SLERILGPAESDEFLARVYEKLITGCYNILAHHSDPNSGLDESILEECLQHLEKQLESSQ ARKAMEEFFSESGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLRLCGS LAQLACVEPVRLQAWLTRMTMSPPKDSDQLDVVQENRQLLQLLTTYIVRENSQVGEGVCT VLLSTLIPMATEMLANGDGTGFPELMVVMATLASAGQGAGHLQLHGAAVDWLGRCKKYLS QKNVVEKMNANVTQGKHVTILECTCHIVSYLADVTNALSQTNGQGPSHLSVDGEERAIEV DSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCT VCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQSEPRVP ESVIRHASTSPAEKAKVTISEGKGPDEEKPKKSSLCRNVEGCREELQSQASFSFAPLVLE MLNFLMDAIQINFQQASAMGSSSRAQQALSELHTLDKSVEMTDQLMVPTLGSQEGAFENV RMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQA DSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLH PQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFLLPSSKIRDVTFLF NEEGKNIIVIMSSAGYIYTQLMEEASSAQHGPFYVTNVLEVNHEDLKDSNGQVAGGGVSV YYSHVLQMLFFSYSQGKSFAATISRANLEVQRLFPINIKSSNGGSKTSPALCQWSEVMNH PGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILL CEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKAAAITTRTSSQVNFPIDFFE HNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEVTNNNSTMVMTGMR IQIGTQAIERAPSYLEIFGRTMQLNMTRARWFDFPFTREEALQADKKLTIFIGASVDPAG VTMMDSIKIYGKTKEQFGWPDEPPEDFPSASVSNVCPPNLNQGNGTGDTESATPAAASGT VLERLVVSSLEALESCFAVGPVNEKEKNKVAAQELATMLLSMPAPSSVQQQTKSLLASLH TSRSAYHNHKDQALLSKAIQYLSSSTKEGKDLDPEVFQRLVITARSIAIMRPNNLVHYTE SKLPQLETENEEGQEVQKHAEGDGCTFITQLVNHFWKLHASKPKNAFLAPACLPGLTHVE ATVNALVDIIHGYCTCELDCIHTASKIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHV TLPSSPRSNTPMGDKDDDDDDDAEDKLQSSGMANGEHIRQESQEQSEVDHGDFEMVSESM VLETSENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSS ALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPADHGGSVG SESGGSAVDSVAGEHSVSGRSSAYGDTAAEGHPAGPGSVSSSTGAISTATGQQEGDGSEG EGEAEGDVHTSNRLHMVRLMLLERLLQNLPQLRNVGGVRAIPYMQVILMLTTDLDGDDEK DKGALDNLLSQLIAELCMDKKDVSKKNERSPVNEVHLVVMRLLSVFMSRTKSGSKSAICE SSSLISSATAAALLSSGAVDYCLHVLKSLLEYWKSQQNDEEPVATSQLLKPHTTSSPPDM SPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPIFDHSWFYFLSE YLMIQQTPFVRRQVRKLLLFICGSKDKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVV TASSGSALQYDTLISLMEHLKACAEIATQRTVNWQKFCIKDDSVLYFLLQVSFLVDEGVS PVLLQLLSCALCGSKVLSVASSSGSSTSSTSAPAASGSGQSATQSKSSTKKSKKEEKEKE REGESSGSQEDQLCTALVNQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLALHIYRN SNKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTQQTEKKLKEYSQKAVEILR TQNHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTT TQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKV QLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCG ENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVTN INTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDESGSSGGISSTSASVNRYILQ LAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTTVQPTFTASQYRA LSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNSAIRHILVSQGLIRELFDYNLRRGA ATMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSAALKGHWANPDLASSLQYEMLLLTDS ISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVP VDSLTTVKPYSNEIHAQAQLWLKRDPKASYEAWKKCLSARVVDANGKSPSKAELHQLYLS EKYVWKWKQFMSRCGKRTCPLDLKLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSR KQQVLDLLTSYLDELSIAGECAAEYLALYQKLIKPSYWKVYLAARGVLPYIGSLITKEIA RLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVV QRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYSLDDYRTPVFIFERLCSI IYPEENEVTEFFVTXXXXXXXXXXXSAEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQ DCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCPTNEGEPMRIIYRMRGLLGDAT EEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLTGIKDFKQGRHLLTVLLKLF SYCVKVKINRQQLVKPEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDE SNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNLSVLQGLLRIIPYLSFGEMEKMQ ILVDRFKPYCNFDKYDEEHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNAL DYMKKHIPSAKNLDADVWKKFLSRPALPFILRLLRGLATQHPSTQVLIGTDSITNLHKLE QVSSDEGIGTLAENLLEALREHPEVNKKIDAARKETRAEKKRMAMAMRQKALGTLGMTTN EKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQ NT seq 12708 nt NT seq  +upstreamnt  +downstreamnt cctcccccaccacctttggagagctcgcctagagtgaaaagccccaacaaacagactgct ggagagaatgggaacatcctggccagccgcaaggatccggaattgtttttgagcctagct tcaaacattctgaactttatcacttcttctatgctgaactccaggaataacttcattcgc aactacctgagcgtgtctctttcagagcaacacatggctacgctagctggcatcatcaag gaggtggataaggacgggcttaagggcacgtcagatgaggagtttgctgctgcactgtat cacttcaaccattccttggtgacctcagatcttcagtcccctgccttgcagaacacactt cttcagcagctgggagttgcccctttttctgaaggtccatggcctctctacatccatcct caaagtttgtcggtgctctcgcgacttctcctgatttggcagcataaagcaactgcccag ggagatcctgatgttccagaatgccttaaagtttgggaaaggtttgtgggcacgctgagg caaaatgccctgcaggggactcttcccagtgacacagaagatctgaatgttgaacatctc cagctgctgctgcttatttttcacaatttctctgagaggggccgcagatctatcatgatg ctctgtatccagacaattgtggagctgacagcgaacatggacacccagcaatgttctgtg ccgcttattgtggcacgtctgctcttggtgtttgactacctgctccatcagttttccaag gcccccatgtatctatttgaacaggtgcaatataatttgctgactccacccattggctgg gtgagtggatcccaggacagtagcagacgaacgtctgtcccgctttatcatgggtttaaa gaagtggaagaaaactggaccaaacactgttcatcagatgcagttccacagcccaggttc tactgcatcctgtccctagaagcctctgaagacgatctgaaccgtctagatggcatggtt tgtgaggtccttttctctaggactatgaagtacgacgagctttacacagccctgacttcg ctacttgcagctggatcgcagtttgatacgctcaggaggaaagagaacaagaatgtcact gcgctggaagcctgtgcactgcagtactacttcctcattctgtggcggatactggggatt ttgcctccatccaaaaactacatgaatcaattggccacgaactctcccgagatgagcgaa tgtgatattttacacacgttgcgctggtcctcccgtctgcggatcacgtcttacgtcacg tggatcaaggatcaccttaccaagcagggcatgaaagctgaccacgcggcgtctctcgtt gaactggcctccagcaagtgcagctcggtgaagtacgatgtggagatcgcagaggaatac tttgctcgacagatctcttctttctgcggtgttgattgcacaaccattctccaactgcac gaagttcccagtttacagtccatttacacccttgatgctgccatttccaagattcaggtt tctctggatgagcacttttccaagctagctgcagaaactgatccacacaagtcttcagag ataaccaagaacctcctgcctgctacgctacagcttattgacacttacgctacgtttacc agatcttacttgctacggagcctctctgaagagggctccccggagaacaaaccctctgaa gagaagctacgaggttatgctgctgtcctggccattggatccagccgttgcaagtctaat actctgggtccaacactcgttcagaacttgccatcggctgtgcagactttgtgtgaatca tggaacaacatccataccaacgagtttccaaacattggctcctggcgcaacgcctttgca aatgacacgatccccgcagaaagctacatcagtgcagtccaggcagcccacctcggtact ctctgcagccaaagtctacctcttgcagcgtccctaaagcacacccttctctccctggtc agactcactggggatctcattgtctggtccgatgacttgaacccaccacaggtgattcac tccctgctgccgctcctgttggagaccagcacagagagcgtggcagagataagcagtaac tccctagaaaggatcttgggccctgcagaatcggatgaattcctggcacgtgtttatgag aaactgatcacaggatgctataacatactggcccatcactctgatccaaacagtggcctg gatgaatccatcctggaggagtgtttgcagcatctggagaaacagctggagagcagccag gcccgaaaagccatggaggaattcttttcagaaagtggagaactggtccagatcatgatg gcgacagccaacgaaaacctctcggcgaagttctgtaacagggtgctgaagttcttcacc aagctcttccagctcactgagaagagtcccaaccccagcctgttgcgactttgtggctct ttggctcagctggcttgcgtggaacctgtccgtctccaggcctggttaaccaggatgacc atgtccccacctaaagattcagatcagctggacgttgtgcaagagaacaggcagctgctg caacttttgacgacttacattgtgcgggaaaacagccaagtcggagaaggcgtgtgcact gttctgctgagtactcttataccaatggcaacggaaatgttggccaacggtgatggcaca ggctttcctgaactgatggtcgtgatggcaactttggctagtgccggacaaggtgccgga cacctccagcttcatggtgctgctgttgactggcttggcagatgcaagaaatacctctct cagaagaatgtggtagaaaaaatgaatgcaaatgtcacgcaaggaaagcacgtgacaatc ctggagtgtacatgccatattgtctcttacctggccgatgtcactaatgcgctgagccag accaacggccaaggaccaagtcatctttctgtcgatggggaggaacgggcgattgaggtg gattcagactgggtggaagagttggcagtggaggaggaggactctcaagctgaagattcg gatgaagattccctttgtaataaactctgtaccttcaccatcacacagaaggagttcatg aatcaacattggtatcactgtcacacttgcaagatggttgatggggtcggtgtttgcaca gtttgtgctaaagtttgtcacaaggatcatgagatttcttacgccaaatacggatcgttc ttctgtgactgtggagccaaggaagatggcagttgcctggctttggtgaagcgaactccc agcagtggcatgagctctaccatgaaagaatccgccttccagagcgagcccagagtgccc gagagcgtcattcgccacgcaagcacctctcctgcagagaaggccaaggtcaccatcagt gaggggaagggccctgatgaagagaaacccaagaagagcagcctgtgtagaaatgttgag ggctgtcgggaggaattgcagtcccaggccagtttctcctttgcgcctttggtgctggag atgctgaatttcctgatggatgccattcagataaacttccagcaagcgtcagccatgggg agcagcagtcgtgcacagcaggctctcagtgagctccataccttggacaagtcagtggaa atgacggatcagttgatggtcccaacgcttggctctcaagaaggtgcttttgagaacgtc cgcatgaactacagtggtgaccagggccagacgatccggcagctgatcagcgctcacgtg ctgaggcgggtggccatgtgcgtgctgtcgtccccgcacggacgtcggcagcacctggct gtcagtcatgaaaagggcaagatcacggtccttcagctctcagcgttgctgaaacaagca gactccagcaaaagaaaattgacccttactcgccttgcgtctgctcccgtcccgttcact gtactgagcctaactggaaatccctgcaaggaggactacctagccgtgtgtggactcaaa gactgccacgtgctaacattcagcagctctggatcagtctctgatcatctggtccttcat ccccaactagccactggaaatttcatcattaaagccgtgtggctgccaggatctcaaacg gagcttgctattgtgaccgcggactttgtgaagatttacgatctctctgtagatgccttg agtccaactttctatttccttctaccgagttccaaaatcagggacgtcactttccttttc aacgaggaggggaagaacatcatagtgatcatgtcctctgctgggtacatctacacacag ctcatggaggaggcgagcagtgcccagcatggaccgttctacgtcaccaatgtgctggaa gtcaaccacgaggacttaaaggacagtaatggccaggtagcaggaggtggtgtgtctgtg tattactcccatgtgctgcagatgttgttcttcagttacagtcaaggcaaatccttcgca gccaccatcagtcgggccaacctggaggtgcagcggctcttccccattaacataaagagt tcaaatggtgggagtaagacttcaccggcgctgtgtcagtggtctgaggtgatgaaccac cctggcttagtgtgctgtgttcagcaaaccaccggtgttccactggtggtgatggtgaag ccggacacctttctcatccaggagattaaaaccttgccagccaaagcaaagattcaggac atggtggccatccgtcacacagcctgcaacgagcagcagaggaccactatgatcctcctg tgtgaagacggcagcctgcggatctacatggccaatgtggagaatacttcctactggctc cagccctccctccagcctagcagcgtcatcagcatcatgaagccggttcgcaagcgcaag gcagccgctattacaactcgcacatccagccaagtgaacttccctatcgacttctttgaa cacaaccagcagctcacagatgtagagtttggaggcaatgacctgctgcaggtgtacaat gcccagcagataaagcacaggctcaattccactggcatgtatgtggccaacacaaagcct gggggtttcaccattgaagtgacaaacaataacagcacgatggtgatgacaggcatgcgg atccagattggcacgcaagcgatagagcgagcgccctcctacctggagatctttggccgc accatgcagctgaacatgaccagggctcgttggtttgatttccctttcactcgggaggaa gccttgcaagctgacaaaaaactaaccatcttcattggagcttctgtggatcctgctgga gtcacaatgatggattccataaaaatctatggcaaaaccaaagagcagtttggatggcct gatgagccccctgaagatttcccatctgcttcagtgagcaacgtttgtcccccaaacctg aatcaggggaatggcactggagacacggagtcggccacccctgctgctgccagcgggact gtcctggagaggctagtagtgagttctttagaagcgctggaaagctgctttgctgtagga ccagtcaacgagaaggagaagaataaggtggcagctcaggaactggccactatgctgctg tccatgccagctccttccagtgtccagcagcaaaccaagagcctcttggctagcttgcac accagccgctccgcataccataaccacaaggatcaagcgttgctaagtaaagccattcag tatttgagctcctcaaccaaagaaggaaaggaccttgatcctgaagtgtttcagaggctg gtcatcactgctcggtccattgctattatgagacccaacaatctggtccattatacggaa tcaaagctgccacagttggaaacagagaacgaagaagggcaggaggtgcagaagcacgct gaaggagatggctgcacatttattacccagctggtcaaccacttctggaagctacatgcg tcaaaacccaaaaatgccttccttgccccagcctgcttgccaggtctcactcatgttgaa gccacagtcaatgctttggtggacattatccacggatactgcacgtgtgaactggattgt atccatacagcatccaagatttacatgcagatgttactttgcccggatcctgcagtgagc ttttcttgcaaacaagctttgatcagggtgctgagaccgaggaacaagcggcgacatgtc accttgccgtcctctcctcggagcaatactcctatgggagataaggatgatgacgacgat gacgacgcagaagacaagctgcagagttctgggatggcaaacggcgagcatatccgacaa gaaagtcaggagcaaagcgaagttgatcacggggacttcgagatggtgtctgaatctatg gttctagagacttcagaaaatgtgaataatgggaacccttctcccctggaggctcttctg gctggagcagagggattcccgcctatgctggatattcctccggatgcagatgacgaaacc atggtggaattggctattgccctgagcctgcaacaagatcagcaagggagcagcagtagt gcgcttggacttcagagcttaggactgtctggccaagcccccagctcttcctctcttgat gccgggacgctctcagatacaacagcatcagctccagcgtctgatgatgaaggcagtaca gccgcgacagacggctcaactcttcgcacctcacctgcagaccatggtgggagtgtgggc tcggagagcggaggcagcgcggtggactccgtagctggtgagcacagcgtgtctggccga agcagtgcctatggggacacggcagctgagggccaccccgccgggccaggcagcgtcagc tcaagcacgggcgctatcagcactgccacgggccagcaagagggcgatggatcggaaggg gaaggggaggcagagggagacgtccacaccagcaacaggctgcacatggtccgactgatg ttgctggagaggctgctgcaaaacttacctcagctgaggaatgttggaggagttcgggcc attccttacatgcaggttattctgatgctcacaacagacctagatggagatgatgagaaa gacaagggagctttagataaccttttgtcccaactcattgcagaactgtgcatggacaaa aaggacgtgtctaagaaaaacgaacgctctcctgtgaacgaagtgcacttggtggtcatg aggctgctcagcgtgttcatgtcccgaactaagtcaggatccaagtctgccatttgtgag tcttcctccctcatctctagtgccaccgccgctgcgttgctgagctcgggtgctgttgac tactgtctgcatgtgctgaagtctttgctggagtactggaaaagccagcagaatgacgag gagcctgtagccaccagccagctcctgaaacctcacactacttcttctccacctgacatg agcccctttttcctccgtcagtatgtgaagggtcacgctgcagatgtttttgaggcctac actcagctcctgaccgagatggtgctgcggctgccctatcagatcaagaagattgcagac acaaactcccgcatcccacctcccatctttgatcactcctggttttacttcttgtctgag tacctgatgatccagcaaactccattcgtgcgccgccaagtccgcaagcttttgctcttc atctgtggatcgaaggataaataccgccagctcagggacctccacacgctggactctcat gttcgcggaatcaaaaagctcctggaagagcaaggcattttcctccgtgccagtgtggtc acagcaagttcaggctctgccctgcagtacgacacgttgatcagcttgatggaacactta aaggcttgtgcagagatcgccacgcagcgaacagtgaactggcagaaattctgcattaaa gatgactcggttctgtatttcctccttcaagtcagcttcctggtagatgaaggagtgtca ccagttctgctgcagttgctgtcttgtgctctgtgtggcagtaaagtgctgtctgtggct tcatcctctggatcaagcacctcttccacctccgctcctgccgcgtcgggttctgggcag tcagcaacgcagagcaaatcctccaccaaaaagagcaagaaagaagaaaaggaaaaggag cgagagggcgagagttcgggcagtcaggaggatcagctgtgcacagccctggtgaaccag ctgaacaagtttgctgataaagagaccctcattcagttcctgcgttgcttcttgctggag tccaactcatcctccgtgagatggcaggcgcactgcctcgcgctccacatctacaggaac tcgaacaagtcccagcaagaattactgttggatctcatgtggtcaatctggccagaactt ccagcctatggcagaaaggctgcccagtttgtagatctcctgggatacttctctctgaaa acacagcagactgagaaaaagttgaaggaatattcccaaaaggcggtggagatcctccgg actcaaaaccacattcttaccaaccaccccaactccaacatttacaacaccctgtctggg ctggtggaatttgatggctattatctggagagcgatccttgccttgtctgcaacaaccca gaggtgcccttctgttacatcaagctttcctccattaaagtggacacgcggtacactacc acccagcaagtggtgaagctcattggcagccacaccatcagcaaggtgacagtgaagata ggagacctgaaacgaaccaaaatggtcagaaccatcaatctctattacaacaacaggaca gtgcaagccatagtggagctgaaaaacaagccggctcgttggcacaaagctaaaaaagtc cagctgaccccaggccagacggaggtgaagattgatttgccgctgcccattgtggcttcg aacctgatgattgaatttgcagatttctacgagaattaccaggcttccacggagaccctg cagtgcccccgctgcagcgcgtccgtcccagccaacccgggggtgtgtgggaactgcggt gaaaacgtgtaccagtgccacaagtgcaggtccattaattacgatgagaaagatcctttc ctttgcaatgcctgtgggttctgtaaatacgctcgctttgacttcatgttgtatgccaag ccctgctgtgcagtggatcccatagaaaatgaagaggatcgaaagaaggcagtaacaaat atcaacactctcctggacaaggctgacagggtctatcaccagctaatgggacaccgtccg cagctggaaaaccttctgtgtaaagtgaatgaagcagctcctgaaaagccacaggatgaa tctggtagcagtggagggatcagttctacctcagctagtgtaaatagatatatactccag ttagcccaagagtattgtggtgactgcaagaactcttttgatgaactttccaaaatcatc cagaaagtgtttgcctctcggaaggaactcttggaatatgatctccagcagagagaggca gcaacgaagtcctcacgaaccactgtccagcccacgtttactgccagccagtatcgtgcc ttgtcagttttaggctgtggccacacgtcatcgacgaaatgctatggctgtgcctcagct gtcactgagcactgcataacgttgctccgggctctggcgaccaactctgccatccggcat atccttgtgtcccagggccttatccgagagctctttgactacaacttgcggcggggcgca gccaccatgcgggaagaggtccgtcagctcatgtgccttctgaccagggacaatccagag gccacacaacaaatgaatgacttaatcatcgggaaggtttctgcagccctgaagggacac tgggcaaatccagacttggctagcagcctccagtatgaaatgttgctgctgacagattcc atctcgaaggaagacagctgctgggagctccgactacgctgtgctcttagcctctttctg atggcagtgaacattaagactccagtcgttgttgaaaacatcaccctcatgtgcctgcgc attcttcaaaagctgatcaagccacccgctccaaccagcaagaaaaacaaggatgtgcct gtggattctctgaccactgtgaagccttacagcaacgaaatccacgcacaagctcagttg tggctcaagagggaccccaaagcatcgtatgaagcttggaaaaagtgcctctctgcccga gttgtagatgccaatgggaaatctcccagcaaagcggaacttcaccagctctacttgtca gagaaatacgtctggaagtggaaacagttcatgagtcgctgcgggaagagaacttgccct ctcgatcttaagctgggacacaacaattggctgcgacaggtgctgtttactcctgccact caggccgcgaggcaggctgcgtgcacgattgtggaagctctggctaccatccccagccgc aaacagcaggtccttgatctcctgacaagctacctggatgagctgagcattgctggcgag tgtgccgcagagtacctggccctctaccagaaactcatcaaaccatcctactggaaggtc tacctggcagccaggggagttctgccctatattggcagcctcatcacaaaggaaatagct cgtttacttgccttggaggaagcaacactcagtaccgatttgcagcagggatatgccttg aagagtctcacaggtctcctctcttccttcgtggaggtggagtccatcaaacggcacttc aaaagccgcctggtgggcacggtcctgaatggttacctgtgtctgaggaagttagtggta caaagaacaaagctgattgatgaaacccaggacatgctgctggagatgctggaggatatg acaacaggcacggaatctgaaaccaaagcatttatggcggtgtgtatagagactgcgaaa cggtacagccttgatgactacaggactcctgtcttcatctttgagagactgtgcagtatc atctaccctgaggagaatgaagtgaccgagttctttgtgactnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnncctcagcggaagacttcttacagggcagaatgccaggaaatccctac agcagtaatgagcctggcattgggcccctcatgagggacatcaagaacaaaatctgtcag gactgtgacctggtagctctgctggaggacgacagtggaatggagcttttggtgaacaat aagatcatcagtttggatctgcctgtggctgaggtctacaagaaggtgtggtgtcccact aatgagggggagccgatgaggatcatttaccgcatgcgagggttactaggagatgcaact gaggaattcatcgagtcgcttgactccactaccgatgaagaagaggatgaggaagaagtt tataagatggcaggtgtcatggcccagtgtggaggcttggagtgcatgctcaacagactg actggaatcaaggacttcaaacaaggccggcacctcttaaccgtgctgttaaaactgttc agttactgtgtgaaggtgaaaataaatcgtcagcagttggtgaagccagagatgaacaca ttgaatgtcatgctgggaacccttaacttggctctggtggctgagcaggaaagtaaagac agtggaggagcggctgtggcagaacaagtgcttagtataatggagatcatactggatgaa tccaacgcagaacctctgagtgaggacaagggtaacctcctcctgaccggtgacaaagac cagctggtaatgctgctcgatcagattaacagcactttcgtccgttccaatctcagcgtc ttgcaagggctgttacgcatcatcccttacctgtccttcggggagatggagaaaatgcag attctggttgatcgcttcaagccctactgtaactttgataagtatgatgaggagcacagt ggagatgacaaagttttcctagactgcttctgtaaaatagcagcgggaataaagaacaac agcaacggccatcagctgaaagatctcatccttcagaaggggattacgcagaatgccctt gactacatgaaaaaacacattcccagtgcaaagaatttggatgcagacgtatggaagaaa ttcttatctcgacctgcacttccttttatcttgcgcctgctccgaggacttgccacacag cacccctctacacaggtgctaataggtacagactccatcaccaacctgcacaaactggag caggtctcgagcgatgaagggatcgggaccttagcagagaatcttctggaggcactgagg gaacatccggaggtcaataagaagatcgatgctgcccggaaggagacacgtgcagagaag aagcgtatggccatggcaatgagacagaaggccttgggcactctggggatgacgacgaat gagaagggtcaggtagtgaccaagactgcgctgcttaaacagatggaggagcttatagaa gagccaggtctgacttgctgcatctgccgggaaggatacaagtttcag

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