Escherichia coli O18 K1 H7 IHE3034 (ExPEC): ECOK1_0074
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Entry
ECOK1_0074 CDS
T01997
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
eih
Escherichia coli O18:K1:H7 IHE3034 (ExPEC)
Pathway
eih00290
Valine, leucine and isoleucine biosynthesis
eih00660
C5-Branched dibasic acid metabolism
eih01100
Metabolic pathways
eih01110
Biosynthesis of secondary metabolites
eih01210
2-Oxocarboxylic acid metabolism
eih01230
Biosynthesis of amino acids
Module
eih_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
eih00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ECOK1_0074 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECOK1_0074 (leuB)
Enzymes [BR:
eih01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
ECOK1_0074 (leuB)
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
DUF6259
Motif
Other DBs
NCBI-ProteinID:
ADE89733
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All DBs
Position
complement(83228..84319)
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AA seq
363 aa
AA seq
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MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPA
TVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAF
CPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAF
ESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQF
DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIA
QILSLALLLRYSLDADDAASAIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYVA
EGV
NT seq
1092 nt
NT seq
+upstream
nt +downstream
nt
atgtcgaagaattaccatattgccgtattgccgggggacggtattggtccggaagtgatg
acccaggcgctgaaagtgctggatgccgtgcgcaaccgatttgcgatgcgtatcaccacc
agccattacgatgtaggcggcgcagccattgataaccacggacagccgctgccgcctgcg
acggttgaaggttgtgagcaagccgatgccgtgctgtttggctcggtaggtggtccgaag
tgggaacatttgccgccagaccagcaaccagaacgcggcgcactgctgcctttgcgtaaa
cacttcaaattattcagcaatctgcgtccggcaaaactgtatcaggggctggaagcgttc
tgcccactgcgtgctgacattgccgcaaacggctttgacatcctgtgtgtgcgcgaactg
accggcggcatctatttcggtcagccaaaaggccgcgaaggtagcggacaatatgaaaaa
gcgtttgataccgaggtgtaccaccgttttgagatcgagcgtattgcccgcatcgcattt
gaatctgcccgcaagcgtcgccacaaagtcacctcaatcgacaaagccaacgtgctgcaa
tcctctattttatggcgggagatcgttaacgagatcgccacggaatacccggatgtcgaa
ctggcgcatatgtacatcgacaacgccaccatgcagctgattaaagatccatcacagttt
gacgtcttgctgtgctccaacctgtttggcgacattctgtctgatgagtgcgcaatgatc
actggctcaatggggatgttgccttccgccagcctgaacgagcaaggttttggtctgtat
gaaccggcgggcggctcggcacccgatatcgcaggtaaaaatatcgccaacccgattgca
caaattctgtcgctggcgctgctgctgcgttacagcctggatgccgatgatgcggcttcc
gccattgaacgcgccattaaccgcgcattagaagaaggcattcgcactggggatttagcc
cgtggcgctgccgccgttagtaccgatgaaatgggcgatatcattgcccgctatgtggca
gaaggggtgtaa
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