Escherichia coli O18 K1 H7 IHE3034 (ExPEC): ECOK1_0120
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Entry
ECOK1_0120 CDS
T01997
Symbol
acnB
Name
(GenBank) aconitate hydratase 2
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
eih
Escherichia coli O18:K1:H7 IHE3034 (ExPEC)
Pathway
eih00020
Citrate cycle (TCA cycle)
eih00630
Glyoxylate and dicarboxylate metabolism
eih00640
Propanoate metabolism
eih00720
Other carbon fixation pathways
eih01100
Metabolic pathways
eih01110
Biosynthesis of secondary metabolites
eih01120
Microbial metabolism in diverse environments
eih01200
Carbon metabolism
eih01210
2-Oxocarboxylic acid metabolism
eih01230
Biosynthesis of amino acids
Module
eih_M00009
Citrate cycle (TCA cycle, Krebs cycle)
eih_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
eih_M00012
Glyoxylate cycle
eih_M00982
Methylcitrate cycle
Brite
KEGG Orthology (KO) [BR:
eih00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ECOK1_0120 (acnB)
00630 Glyoxylate and dicarboxylate metabolism
ECOK1_0120 (acnB)
00640 Propanoate metabolism
ECOK1_0120 (acnB)
09102 Energy metabolism
00720 Other carbon fixation pathways
ECOK1_0120 (acnB)
Enzymes [BR:
eih01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
ECOK1_0120 (acnB)
4.2.1.99 2-methylisocitrate dehydratase
ECOK1_0120 (acnB)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ADE88283
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Position
137718..140315
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AA seq
865 aa
AA seq
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MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEA
AYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS
HTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTD
DLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVV
GTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN
LNMGDVIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREA
LGLPHSDVFRQAKDVAESDRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPM
TRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGDGVIH
SWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKM
QPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASA
ERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEA
DADAEYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAA
GKLLDAHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVA
DGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDT
YRYLNFDQLSQYTEKADGVIFQTAV
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
gtgctagaagaataccgtaagcacgtagctgagcgtgccgctgaggggattgcgcccaaa
cccctggatgcaaaccaaatggccgcacttgtagagctgctgaaaaacccgcccgcgggc
gaagaagaattcctgttagatctgttaaccaaccgtgttccccctggcgtcgatgaagcc
gcctatgtcaaagcaggcttcctggctgctgtcgccaaaggcgaagctaaatccccgctg
ctgactccggaaaaagccattgaactgctgggcactatgcagggtggttacaacattcat
ccgctgatcgacgcgctggatgatgccaaactggcaccgatcgctgccaaagcactttct
cacacgctgctgatgttcgataacttctatgacgtagaagagaaagccaaagcaggcaac
gaatatgcgaagcaggtaatgcagtcctgggcggatgccgaatggttcctgaatcgcccg
gcgctggctgaaaaactgaccgttaccgtcttcaaagtcactggcgaaaccaacaccgat
gacctctctccggcaccagatgcgtggtcacgcccggatatcccactgcacgcgctggcg
atgctgaaaaacgcccgtgaaggtattgagccagatcagcctggtgttgttggcccgatc
aaacagattgaagctctgcaacagaaaggtttcccgctggcgtacgtcggtgacgttgtg
ggtacgggttcatcgcgtaaatccgccacgaactccgttctgtggtttatgggcgatgat
attccacatgtgccgaacaaacgcggcggtggtttgtgcctcggcggtaaaattgcacca
atcttttttaacacgatggaagacgcgggtgcactgccaatcgaagtcgacgtctctaac
ctgaacatgggcgacgtaattgacgtttacccgtacaaaggtgaagtgcgtaaccacgaa
accggcgaactgctggcaaccttcgaactgaaaaccgacgtgctgattgatgaagtgcgt
gctggcggccgtattccgctgattatcgggcgtggcctgaccaccaaagcgcgtgaagca
cttggcctgccgcacagcgatgtgttccgtcaggcgaaagatgtcgctgagagcgaccgt
ggcttctcgctggcgcagaaaatggtgggccgagcctgtggcgtgaaaggcattcgtccg
ggcgcgtactgtgaaccgaaaatgacttctgtaggttcccaggacaccaccggcccgatg
acccgtgatgaactgaaagacctggcgtgcctgggcttctcggctgacctggtgatgcag
tctttctgccacaccgcggcgtatccgaagccagttgacgtgaacacgcaccacacgctg
ccggacttcattatgaaccgtggcggtgtgtcgctgcgtccgggtgacggcgtaatccac
tcctggctgaaccgtatgctgctgccggataccgtcggtaccggtggtgactcccatacc
cgtttcccgatcggtatctctttcccggcgggttctggtctggtggcatttgcagccgca
acaggcgtaatgccgctggatatgccagaatccgttctggtgcgcttcaaaggcaaaatg
cagccgggtatcaccctgcgcgatctggtacacgcgatcccgctgtatgcaatcaaacaa
ggtctgctgaccgttgagaagaaaggtaagaaaaacatcttctctggccgcattctggaa
attgaaggtctgccggatctgaaagttgagcaggcatttgagctgaccgatgcgtctgcc
gagcgttctgctgccggttgtaccatcaagctgaacaaagaaccgatcattgaatacctg
aactctaacatcgtcctgctgaagtggatgatcgcggaaggttacggcgatcgtcgtacc
ctggagcgtcgtattcagggcatggaaaaatggctggcgaatcctgagctgctggaagcc
gatgcagatgcggaatacgcggcagtgatcgacatcgatctggcggatatcaaagagcca
atcctctgtgcaccgaatgacccggacgacgcacgtccgctgtctgcggtacagggcgag
aagatcgacgaagtatttatcggttcttgcatgactaacatcggtcacttccgtgctgct
ggtaaactgctggatgcgcacaaaggtcagttgccgacccgcctgtgggtggcaccgcca
acgcgtatggacgctgcgcagctgaccgaagaaggctactacagcgtcttcggtaagagt
ggtgctcgtatcgagatccctggctgttccctgtgtatgggtaaccaggcgcgtgtagca
gacggtgcgacggtggtttccacctctacccgtaacttcccgaaccgtttgggtactggc
gcgaatgtcttcctggcttctgcggaactggctgctgttgcggcgctgattggcaaactg
ccgacgccggaagagtaccagacctacgtggcgcaggtagataaaacagccgttgatact
taccgttatctgaacttcgaccagctttctcagtacaccgaaaaagcggacggggtgatt
ttccagactgcggtttaa
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