Escherichia coli O18 K1 H7 IHE3034 (ExPEC): ECOK1_2501
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Entry
ECOK1_2501 CDS
T01997
Symbol
menD
Name
(GenBank) 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
eih
Escherichia coli O18:K1:H7 IHE3034 (ExPEC)
Pathway
eih00130
Ubiquinone and other terpenoid-quinone biosynthesis
eih01100
Metabolic pathways
eih01110
Biosynthesis of secondary metabolites
eih01240
Biosynthesis of cofactors
Module
eih_M00116
Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol
Brite
KEGG Orthology (KO) [BR:
eih00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
ECOK1_2501 (menD)
Enzymes [BR:
eih01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
ECOK1_2501 (menD)
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Motif
Pfam:
TPP_enzyme_M_2
TPP_enzyme_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
ADE90835
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Position
complement(2591780..2593450)
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AA seq
556 aa
AA seq
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MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGH
LALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAI
RQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDD
TGISWQQRLGDWWQDDKPWLREAPRRESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALW
AQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQAS
CEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAV
IARRDAFGEAQLAHRISDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDG
LLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPT
PKSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETTLVDAWRTPTTTVIEMVVNDT
DGAQTLQQLLAQVSHL
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgtcagtaagcgcatttaaccgacgctgggcggcggtcattctggaagcattaacgcgt
cacggcgtcagacacatctgtatcgcccctggctcgcgttctacaccgttaacgttagcg
gcggcggagaattccgcatttattcatcatacccatttcgatgagcgtggactggggcat
ctggcactggggctggcgaaagtcagcaagcagccggtggcggtgattgtgacctccggc
acggcggtagcaaatctctatccggcactgattgaagctgggttaaccggagaaaaactg
atcctgttaaccgccgatcgcccgccggagctgattgactgcggcgcgaatcaggcgatt
cgtcagccgggaatgttcgcctctcaccccacgcacagtatttcactgccgcgcccgacc
caggatatccccgcacgttggctggtttctaccatcgaccacgctctcggtacgcttcat
gctggtggagtccatatcaactgcccgtttgctgaaccgctgtatggcgaaatggacgac
accgggattagctggcaacagcggctgggcgactggtggcaggacgacaaaccgtggctg
cgtgaagcgcctcgtcgggaaagtgaaaaacagcgtgactggttcttctggcgacaaaag
cgcggcgtggtggttgccgggcgcatgagtgcggaagagggcaaaaaagttgcactgtgg
gcgcaaactcttggctggccgctgattggcgacgtgctgtcgcaaaccggacagccgctg
ccgtgtgccgatctctggttaggcaatgccaaagcgaccagcgaactgcaacaggcacaa
atagtggtgcaactgggaagcagcctgacggggaaacgactcctccaatggcaggcaagc
tgtgaaccagaagagtactggattgttgatgacattgaagggcgacttgatccggcacac
catcgcggacgtcgcttaattgccaatattgccgactggctggagctgcatccggcagaa
aaacgccagccctggtgcgttgaaatcccgcgcctggcggaacaggcaatgcaggcggtt
attgcccgtcgcgatgcgtttggcgaagcgcaactggcgcatcgcatcagcgactacttg
cctgaacaggggcaattgtttgtcggtaacagcctggtggtgcgtctgattgatgcgctt
tcgcaacttccggcaggttacccggtgtacagcaaccgtggtgccagcggtatcgacggg
ctgctctcgactgccgccggcgttcagcgggcaagcggcaaaccgacgctggcgattgtg
ggcgatctctccgcactttacgatctcaacgcgctggcgttattgcgccaggtttccgca
ccgctggtattaattgtggtgaacaacaacggcgggcaaattttttcgctgttgccaacg
ccgaaaagcgagcgcgagcgtttctatctgatgccgcaaaacgtccattttgagcacgcc
gctgcgatgttcgagctgaaatatcatcgtccgcaaaactggcaggaacttgaaacgaca
ctagtcgatgcctggcgtacgccgaccaccacggtgattgaaatggtggttaacgacacc
gatggtgcgcaaacgctccagcaacttctggcgcaggtaagccatttatga
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