Escherichia coli O18 K1 H7 IHE3034 (ExPEC): ECOK1_3058
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Entry
ECOK1_3058 CDS
T01997
Symbol
gshA
Name
(GenBank) glutamate--cysteine ligase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
eih
Escherichia coli O18:K1:H7 IHE3034 (ExPEC)
Pathway
eih00270
Cysteine and methionine metabolism
eih00480
Glutathione metabolism
eih01100
Metabolic pathways
eih01240
Biosynthesis of cofactors
Module
eih_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
eih00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ECOK1_3058 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
ECOK1_3058 (gshA)
Enzymes [BR:
eih01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
ECOK1_3058 (gshA)
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Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
ADE89894
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All DBs
Position
complement(3127189..3128745)
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AA seq
518 aa
AA seq
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MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTD
FAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYG
TSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGY
FRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALA
DAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTL
DSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPL
EILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatcctcaggcgttaaag
gggatacagcgtgggctggagcgcgaaactttgcgtgttaatgctgatggcacactggca
acaacaggtcatcctgaagcattaggttctgcactgacccataaatggattactaccgat
tttgcggaagcattgctggaatttattacaccagtggatggtgatattgaacatatgctg
acctttatgcgcgatctgcatcgctatacggcgcgcaatatgggcgatgagcggatgtgg
ccgttaagtatgccatgctatatcgcagaaggtcaggacatcgaactggcacagtacggc
acttctaacaccggtcgctttaaaacgctgtaccgtgaagggctgaaaaatcgctacggc
gcgctgatgcaaaccatttccggcgtgcactataatttctctttgccaatggcattctgg
caagcgaagtgcggtgatatctcgggcgctgatgccaaagagaaaatttctgcgggctat
ttccgcgttatccgcaattactatcgtttcggttgggtcattccttatttgtttggtgcg
tctccagcgatttgttcttctttcttgcaaggaaaaccaacgtcgctgccgtttgagaaa
accgagtgcggtatgtattacctgccgtatgcgacctctcttcgtttgagcgatcttggc
tataccaataaatcgcaaagcaatcttggtatcaccttcaatgatctctacgagtacgtg
gcgggccttaaacaggcaatcaaaacgccatcggaagagtacgcgaagattggtattgag
aaagacggtaagcggctgcaaatcaacagcaatgtgctgcagattgaaaacgaactgtac
gcgccgattcgtccaaaacgcgttacccgcagtggtgagtcgccttctgatgcgctgtta
cgtggcggcattgaatatattgaagtccgctcgctggatatcaacccgttctcgccgatt
ggtgtagatgaacaacaggtgcgattcctcgacctgtttatggtctggtgtgcgctggct
gacgcaccggaaatgagcagtagcgaacttgcctgtacacgcgttaactggaaccgggtg
atcctcgaaggtcgcaaaccgggcctgacgctgggtatcggctgcgaaaccgcgcagttc
ccgttaccgcaggtgggtaaagatctgttccgcgatctgaaacgcgtcgcgcaaacgctg
gatagcattaacggcggcgaagcgtatcagaaagtgtgtgatgaactggtcgcctgcttc
gataatcccgatctgactttctctgcccgtatcttaaggtctatgattgatactggtatt
ggcggaacaggcaaagcgtttgctgaagcgtaccgtaatctgctgcgtgaagagccgctg
gaaattctgcgcgaagaggattttgtcgccgagcgcgaggcgtctgaacgccgtcagcag
gaaatggaagccgctgataccgaaccgtttgcggtgtggctggaaaagcacgcctga
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