Escherichia coli O18 K1 H7 IHE3034 (ExPEC): ECOK1_4218
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Entry
ECOK1_4218 CDS
T01997
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
eih
Escherichia coli O18:K1:H7 IHE3034 (ExPEC)
Pathway
eih00290
Valine, leucine and isoleucine biosynthesis
eih00770
Pantothenate and CoA biosynthesis
eih01100
Metabolic pathways
eih01110
Biosynthesis of secondary metabolites
eih01210
2-Oxocarboxylic acid metabolism
eih01230
Biosynthesis of amino acids
Module
eih_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
eih_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
eih00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECOK1_4218 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
ECOK1_4218 (ilvD)
Enzymes [BR:
eih01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
ECOK1_4218 (ilvD)
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GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
ADE92813
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Position
4327246..4329096
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AA seq
616 aa
AA seq
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MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLV
AEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCIS
NCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQ
SDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIV
ELTKRYYEQDDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSD
IDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQT
LEQYDIIVTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDTLDDDRSNGCIRSLEHAYSKDG
GLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRY
EGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGL
IEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLA
TSADKGAVRDKSKLGG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgcctaagtaccgttccgccaccaccactcatggtcgtaatatggcgggtgctcgtgcg
ctgtggcgcgccaccggaatgaccgacgccgatttcggtaagccgattatcgcggttgtg
aactcgttcacccaatttgtaccgggtcacgtccatctacgcgatctcggtaaactggtt
gccgaacaaattgaagcggctggcggcgttgccaaagagttcaacaccattgcggtggat
gatgggatcgctatgggccacgggggcatgctttattcactgccatctcgcgaactgatc
gctgattccgttgaatatatggtcaacgcccactgcgccgacgccatggtctgcatctct
aactgcgacaaaatcaccccggggatgctgatggcttccctgcgcctgaatattccggtg
atctttgtttccggcggcccgatggaggccgggaaaaccaaactgtccgatcagatcatt
aagctcgatctggttgatgcgatgatccagggcgcagacccgaaagtttctgactcccag
agcgatcaggttgaacgatccgcctgcccaacctgcggttcctgctccgggatgtttact
gctaactcaatgaactgcctgaccgaagcgctgggcctgtcgcagccgggcaacggctcg
ctgctggcaacccacgctgatcgcaagcaactgttcctcaatgctggtaaacgcattgtt
gaattgaccaaacgttactacgaacaggatgatgaaagcgcactgccgcgtaacatcgcc
agtaaggcggcgtttgaaaacgccatgacgctggatatcgcgatgggcggctctaccaac
accgttctccacctgctggcggcggcgcaggaagcggaaatcgacttcaccatgagtgat
atcgataagctctcccgcaaagtaccgcagctgtgtaaagttgcgccgagcacccaaaaa
taccatatggaagatgttcaccgtgctggtggtgttatcggtattctcggcgagctggat
cgtgcggggttactgaaccgtgatgtgaaaaatgtacttggcctgacgttgccgcaaacg
ctggaacaatacgacatcatcgtgacccaggatgatgcggtaaaaaatatgttccgcgct
ggcccggcgggcattcgtactacacaggcattctcgcaggattgccgctgggatacgctg
gacgacgatcgctccaatggctgtatccgctcgctggaacacgcctacagcaaagacggc
ggcctggcggtgctctacggtaatttcgcagaaaacggctgcatcgttaaaaccgcaggc
gtcgatgacagcatcctcaaattcactggcccggcgaaagtctacgaaagccaggacgac
gcggtagaagcgattctcggcggtaaagttgtcgccggagatgtggtagtaattcgctat
gaaggcccgaaaggcggtccggggatgcaggaaatgctctacccaaccagtttcctgaaa
tcaatgggtctcggtaaagcctgtgcgctgatcaccgacggtcgtttctctggcggcacc
tctggtctttccatcggccacgtctcaccggaagcggcaagtggcggcagcattggcctg
attgaagatggtgacctgatcgctatcgacattccgaaccgtggcattcagttacaggta
agcgatgccgaactggcggcgcgtcgtgaagcgcaggaagctcggggtgacaaagcctgg
acgccgaaaaaccgtgaacgtcaggtttcctttgcgctgcgtgcctacgccagcctggca
accagcgccgacaaaggcgcggtgcgcgataaatcgaaactggggggttaa
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