Escherichia coli O18 K1 H7 IHE3034 (ExPEC): ECOK1_4470
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Entry
ECOK1_4470 CDS
T01997
Symbol
thiC
Name
(GenBank) thiamine biosynthesis protein ThiC
KO
K03147
phosphomethylpyrimidine synthase [EC:
4.1.99.17
]
Organism
eih
Escherichia coli O18:K1:H7 IHE3034 (ExPEC)
Pathway
eih00730
Thiamine metabolism
eih01100
Metabolic pathways
eih01240
Biosynthesis of cofactors
Module
eih_M00127
Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
Brite
KEGG Orthology (KO) [BR:
eih00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00730 Thiamine metabolism
ECOK1_4470 (thiC)
Enzymes [BR:
eih01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.17 phosphomethylpyrimidine synthase
ECOK1_4470 (thiC)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ThiC_Rad_SAM
ThiC-associated
Motif
Other DBs
NCBI-ProteinID:
ADE89027
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Position
complement(4594740..4596635)
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AA seq
631 aa
AA seq
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MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSK
EQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKA
RLADDGLDELRFSGVLTPKRAKAGHRVTQLHYARKGIITPEMEFIAIRENMGRERIRSEV
LRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQAL
EKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMA
KWCLSHHQENFLYQRFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELT
KIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAM
SKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDY
AAAQTIEVGMADMSENFRARGGEIYLRKEEA
NT seq
1896 nt
NT seq
+upstream
nt +downstream
nt
atgtctgcaacaaaactgacccgccgcgaacaacgcgcccaggcccaacattttatcgac
accctggaaggctccgcctttcccaactcaaaacgcatttacatcactggcacacacccc
ggcgtacgcgtgccgatgcgtgagattcagcttagcccgacgctaattggcggcagcaaa
gaacagccgcagtacgaagaaaacgaagcgattccggtctacgacacctccggcccgtat
ggcgatccgcagattgccattaacgtgcagcaagggctggcaaaactacgccagccgtgg
atcgatgcgcgcggcgataccgaagaacttaccgtgcgcagttccgattacacaaaagcg
cggctggcagatgatggcctcgacgagctgcgttttagcggcgtattaaccccaaaacgc
gccaaagcaggccaccgcgtcacacaactgcactacgcccgcaagggtatcatcacgcca
gaaatggaattcatcgccattcgcgagaatatgggtcgcgagcgcatacgtagcgaagtt
ttacgccaccagcatccgggaatgagctttggcgcacgtctgccggaaaatatcactgcg
gaatttgtccgtgatgaagttgctgccggacgtgcgattatcccggccaacattaatcat
ccggaatcggagccgatgattattggccgtaacttcctagtaaaagttaacgccaatatc
ggcaactcagcggtcacttcttccatcgaagaagaagtggaaaaactggtatggtccaca
cgctggggagcggataccgtgatggatctttccactggtcgctatattcacgaaacccgc
gagtggattttgcgtaacagcccggtgccgatcggtacagtgccgatctaccaggcactg
gagaaggtgaacgggatcgctgaagatcttacctgggaagtcttccgcgacaccctgctg
gaacaagccgagcaaggtgtggattacttcacgatccatgcgggggtgctgctgcgctac
gtgccgatgaccgcgaaacgcctgaccggtatcgtctctcgcggcggttcgattatggcg
aaatggtgcctctcccatcatcaggaaaatttcctctatcaacgcttccgcgaaatttgt
gaaatctgtgctgcttatgacgtttcgctatcgctgggcgacggcctgcgccccggttct
attcaggacgccaacgatgaagcacagtttgccgagctgcatacgctgggtgaactgact
aaaatcgcctgggaatatgacgtacaggtgatgattgaaggcccaggccacgtgccgatg
cagatgattcgccgcaatatgaccgaggagttagagcactgccacgaagcgccgttttac
actctggggccgctaactaccgatatcgcgccgggctatgaccacttcacgtcagggatt
ggcgcggcgatgattggctggtttggttgtgcaatgctctgctacgtaacgccgaaagag
catctgggcctgccaaataaagaagatgttaaacaggggcttatcacctataagattgcc
gctcacgccgccgacctggcgaaagggcatccgggcgcgcaaattcgcgataacgccatg
tcgaaagcccgcttcgaatttcgctgggaagaccagtttaatctggccctcgacccgttt
actgcccgcgcttatcacgatgaaaccctgccgcaagagtccggtaaagtcgcccatttt
tgctccatgtgtggaccgaaattctgctcgatgaaaatcagccaggaagtgcgtgattac
gccgccgcgcaaaccattgaagtgggaatggcggatatgtcggagaacttccgcgccaga
ggcggagaaatctacctgcgtaaggaggaagcgtga
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