Eumetopias jubatus (Steller sea lion): 114197699
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Entry
114197699 CDS
T07240
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju04217
Necroptosis
eju04380
Osteoclast differentiation
eju04620
Toll-like receptor signaling pathway
eju04621
NOD-like receptor signaling pathway
eju04630
JAK-STAT signaling pathway
eju04658
Th1 and Th2 cell differentiation
eju04659
Th17 cell differentiation
eju05145
Toxoplasmosis
eju05160
Hepatitis C
eju05161
Hepatitis B
eju05162
Measles
eju05164
Influenza A
eju05165
Human papillomavirus infection
eju05167
Kaposi sarcoma-associated herpesvirus infection
eju05168
Herpes simplex virus 1 infection
eju05169
Epstein-Barr virus infection
eju05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
114197699 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
114197699 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
114197699 (TYK2)
04621 NOD-like receptor signaling pathway
114197699 (TYK2)
04658 Th1 and Th2 cell differentiation
114197699 (TYK2)
04659 Th17 cell differentiation
114197699 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
114197699 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
114197699 (TYK2)
05160 Hepatitis C
114197699 (TYK2)
05171 Coronavirus disease - COVID-19
114197699 (TYK2)
05164 Influenza A
114197699 (TYK2)
05162 Measles
114197699 (TYK2)
05168 Herpes simplex virus 1 infection
114197699 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
114197699 (TYK2)
05169 Epstein-Barr virus infection
114197699 (TYK2)
05165 Human papillomavirus infection
114197699 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
114197699 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eju01001
]
114197699 (TYK2)
Enzymes [BR:
eju01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
114197699 (TYK2)
Protein kinases [BR:
eju01001
]
Non-receptor tyrosine kinases
JAK family [OT]
114197699 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
Kdo
FERM_C_FAK1
RA_2
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
114197699
NCBI-ProteinID:
XP_027944599
LinkDB
All DBs
Position
Unknown
AA seq
1182 aa
AA seq
DB search
MPLCHWGATTRDSRPDGDGAQPMATRGGLKVLLHWAGPGGGDPWVTFSEATLTAEEVCIH
IAQKVGITPSCLNLFALFDAQAQVWLPPNHVLEISGDMSLTLYFRMRFYFRNWHGTNPQE
PAVYRCGPPGPKSSSEQAEQGMQLLDPASFEYLFEQGKHEFVNDVASLSELSSEEEIHHF
KNESLGMAFLHLCHLALYHGIPLGKVAKKISFKDCIPRSFRLQIRQHNALTRLRLRNIFR
RFVRAFQPGHVSQQVIMVKYLATLELLAPRFGTERLPVCHLELPAQAVGEPYYIRDGGQA
PSEPGPELATGPPTHEVLVTGTGGIQWRPIHAEGPRGDGSSRNPRAGPFGKKTKVPEVGN
QPEDRPQEAPWAYFCDFKDITHVVLKERHVSIRCQDNKSLELTLPSRAMALSLVSLVDGY
FRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLAKLRPEDGLYLIHWSTSHLNRL
ILTVAQREQAPGTQHLHLRKFPIELQAGGFMLEGWDRSFPSVRELRAALQGCSLRAGDDC
FSLRRCCLPRPGEISNLIIMRGHRASTGPPNLSQLSFHRICQDDITQLSHLGQGTRTNVY
EGILRVGGRGPKEGTANDEDPPTPGGDCGQELRVVLKVLDPSHHDIALAFYETASLMSQV
SHVHLAFVHGICVHGSENIMVTEYVEHGPLDVWLRREKGHVPVAWKVAVAQQLASALSYL
EDKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWTAPECLS
GGANSLTTAADKWGFGATLLEICFDGEAPLQGRGPSEKECFYQKQHRLPQPSCPELATLT
SQCLTYEPAQRPSFRTILRDLTQLQPQNLADLLAVNPDSPASDPTIFHKRYLKKIRDLGE
GHFGKVSLSCYDPTNDGTGEMVAVKALKADCGPQLRSGWRREIDILRTLYHKHIVKYKGC
CEDPGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYVHRDLA
ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVW
SFGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPERCPCEIY
LLMKNCWEAEASFRPTFQNLIPILKTVQEKYQGQAASVFSVC
NT seq
3549 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccattggggtgccaccaccagggacagcaggcctgatggcgatggagct
cagcccatggccaccaggggaggcctgaaggtccttctgcactgggctggccctggcggc
ggggacccctgggtcaccttcagcgaggccacactgaccgcagaggaggtctgcatccac
attgcacaaaaagtcggcatcactccgtcctgcctcaatctctttgctctcttcgatgcc
caggctcaggtctggctgcccccaaaccacgtcttggagatctccggagacatgagcctg
acattgtacttccggatgaggttttatttccggaactggcatggcacgaatcctcaggag
ccggctgtataccgctgtgggcccccagggcccaagtcttcctcagaacaggcagagcag
gggatgcaactgctggacccagcctcctttgagtacctctttgagcagggcaagcatgag
tttgtgaatgacgtggcatcgctgtcagagctgtcgagcgaggaggagatccaccatttt
aagaacgagagtctgggcatggccttcctgcatctctgccaccttgctctctaccacggc
atccccctggggaaggtggccaagaagatcagcttcaaggactgcatcccacgctccttc
cggctgcagatccggcagcacaacgcgctcacgcggctgcgcctgcggaacatcttccgc
aggttcgtgcgggccttccagccaggccacgtgtcacagcaggtcatcatggtcaaatac
ctggccacgctcgagctgctggcaccccgctttggcactgagcgcctgcccgtgtgccac
ctggagctgccggcccaggccgtcggggagccctactacatccgggacggcgggcaggct
ccctcagagcctgggccggagttggccaccgggccccccactcatgaggtgctggtgacg
ggcacgggtggcatccagtggcggccgatacacgcagagggtcccagaggtgatggcagc
agcaggaatccccgtgctggcccatttgggaagaaaaccaaggtcccagaggtgggcaac
cagcccgaggacaggcctcaggaagcgccctgggcctacttctgtgacttcaaggatatc
acgcacgtggtgctgaaggaacgccacgtcagcatccgctgtcaggacaacaagagcctg
gagctgaccctgccttcccgggccatggccctgtccttggtgtcgctggtggacggctat
ttccgcctgaccgctgactcgagccactacctgtgccacgaggtggctccgccacggcta
gtgatgagcatccaggacggtatccacggacccctgctggagccatttgtgctggccaag
ctgcggcctgaggatggcctctacctcatccattggagcaccagccacctcaaccgcctc
atcctcacggtggcccagcgtgagcaggccccgggcacacagcacctgcacctgcgtaaa
ttccccattgagctgcaggccgggggcttcatgctggagggctgggaccggtccttcccc
agcgtgcgggagctgcgggctgccctccagggttgctccctgcgggctggtgatgactgt
ttctccctgcgccgctgctgcctgcctcggccgggagagatctccaacctcatcatcatg
cgggggcatcgggccagcactggtccgcccaacctcagccagctcagcttccaccggatc
tgccaggatgacatcacccagctgtcccacttgggccaaggcacgaggaccaatgtgtat
gagggcatcttacgagtggggggcagaggccccaaggagggcactgccaatgatgaggac
ccccccacgcccggtggggactgtgggcaagagctccgagtggtactcaaggtgctggac
cccagtcaccacgacatcgccctggccttctacgagacagccagcctcatgagccaggtt
tcccacgtgcacctggcctttgtacacggcatctgcgtgcacggctctgagaacatcatg
gtaacagagtacgtggagcacgggcccctggacgtgtggctgcggcgggagaagggccac
gtgcctgtggcctggaaggtggccgtggcccagcagctggccagcgccctcagctatctg
gaagacaagagcctggttcatggtaatgtgtgtggccggaacatcctgctggcgaggctg
ggactggcagagggcactagccccttcatcaagctgagcgaccctggtgtgggcctgggt
gccctttctagggaggagcgggtggagcggatcccctggacagcccccgagtgcctatct
ggcggagccaacagcctaaccactgcagccgataaatggggctttggtgccaccctcctg
gagatctgctttgacggggaggcccctctgcagggccgtggcccttctgagaaagagtgc
ttctaccagaagcagcaccggcttcctcagccctcctgcccggagctggccacactcacc
agccagtgcctgacctatgaaccagctcagcggccctccttccgcaccatcctgcgtgac
ctcactcagctgcagccccaaaatcttgctgacctcttggctgtgaaccccgactcgcct
gcgtcagaccccaccattttccacaagcgctatttgaaaaagatccgggatctgggcgag
ggtcatttcggcaaggtcagcctgtcctgctacgaccccacgaacgacggcaccggcgag
atggtggccgtgaaggccctcaaggcggactgcggcccccagctccgcagcggctggagg
cgggagatcgacatcctgcgcacgctctaccacaagcacatcgtcaagtacaagggctgc
tgcgaggacccaggcgagaagtcggtgcagctggtcatggagtacgtgcccctgggaagc
ctgcgggactacctgccccggcacagcgtgggcctggcgcagctgcttctcttcgcccag
cagatctgtgagggcatggcctaccttcacgcacagcactacgtgcaccgagacctggct
gcccgcaacgtgctgctggacaacgacaggctggtcaaaatcggggactttggcctagcc
aaggctgtgcctgaaggccatgagtactaccgcgtgcgggaagatggggacagccccgta
ttctggtatgccccagagtgcctgaaggagtgtaagttctactatgcatctgacgtctgg
tccttcggggtcaccatgtatgagctgctgacctactgtgactccagccagagccccccg
tcgaaattcatcgagctcataggcctcacccaggggcagatgacggtgctgaggctcact
gagctgctggaacgaggggagaggctgccccggccagagagatgtccttgtgagatctat
ctcctcatgaagaactgctgggaggcagaggcttcattccgccccaccttccagaacctc
atacccattctcaagacagtccaggagaaataccaaggccaggctgcctccgtgttcagt
gtgtgctga
DBGET
integrated database retrieval system
