KEGG   Eumetopias jubatus (Steller sea lion): 114197723
Entry
114197723         CDS       T07240                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
eju  Eumetopias jubatus (Steller sea lion)
Pathway
eju01522  Endocrine resistance
eju04010  MAPK signaling pathway
eju04014  Ras signaling pathway
eju04020  Calcium signaling pathway
eju04024  cAMP signaling pathway
eju04062  Chemokine signaling pathway
eju04081  Hormone signaling
eju04082  Neuroactive ligand signaling
eju04114  Oocyte meiosis
eju04140  Autophagy - animal
eju04211  Longevity regulating pathway
eju04213  Longevity regulating pathway - multiple species
eju04261  Adrenergic signaling in cardiomyocytes
eju04270  Vascular smooth muscle contraction
eju04310  Wnt signaling pathway
eju04340  Hedgehog signaling pathway
eju04371  Apelin signaling pathway
eju04530  Tight junction
eju04540  Gap junction
eju04611  Platelet activation
eju04713  Circadian entrainment
eju04714  Thermogenesis
eju04720  Long-term potentiation
eju04723  Retrograde endocannabinoid signaling
eju04724  Glutamatergic synapse
eju04725  Cholinergic synapse
eju04726  Serotonergic synapse
eju04727  GABAergic synapse
eju04728  Dopaminergic synapse
eju04740  Olfactory transduction
eju04742  Taste transduction
eju04750  Inflammatory mediator regulation of TRP channels
eju04910  Insulin signaling pathway
eju04911  Insulin secretion
eju04912  GnRH signaling pathway
eju04913  Ovarian steroidogenesis
eju04914  Progesterone-mediated oocyte maturation
eju04915  Estrogen signaling pathway
eju04916  Melanogenesis
eju04918  Thyroid hormone synthesis
eju04919  Thyroid hormone signaling pathway
eju04921  Oxytocin signaling pathway
eju04922  Glucagon signaling pathway
eju04923  Regulation of lipolysis in adipocytes
eju04924  Renin secretion
eju04925  Aldosterone synthesis and secretion
eju04926  Relaxin signaling pathway
eju04927  Cortisol synthesis and secretion
eju04928  Parathyroid hormone synthesis, secretion and action
eju04934  Cushing syndrome
eju04935  Growth hormone synthesis, secretion and action
eju04961  Endocrine and other factor-regulated calcium reabsorption
eju04962  Vasopressin-regulated water reabsorption
eju04970  Salivary secretion
eju04971  Gastric acid secretion
eju04976  Bile secretion
eju05012  Parkinson disease
eju05020  Prion disease
eju05030  Cocaine addiction
eju05031  Amphetamine addiction
eju05032  Morphine addiction
eju05034  Alcoholism
eju05146  Amoebiasis
eju05163  Human cytomegalovirus infection
eju05165  Human papillomavirus infection
eju05166  Human T-cell leukemia virus 1 infection
eju05200  Pathways in cancer
eju05203  Viral carcinogenesis
eju05205  Proteoglycans in cancer
eju05207  Chemical carcinogenesis - receptor activation
eju05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:eju00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114197723 (PRKACA)
   04014 Ras signaling pathway
    114197723 (PRKACA)
   04310 Wnt signaling pathway
    114197723 (PRKACA)
   04340 Hedgehog signaling pathway
    114197723 (PRKACA)
   04371 Apelin signaling pathway
    114197723 (PRKACA)
   04020 Calcium signaling pathway
    114197723 (PRKACA)
   04024 cAMP signaling pathway
    114197723 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    114197723 (PRKACA)
   04081 Hormone signaling
    114197723 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    114197723 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    114197723 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    114197723 (PRKACA)
   04540 Gap junction
    114197723 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    114197723 (PRKACA)
   04062 Chemokine signaling pathway
    114197723 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    114197723 (PRKACA)
   04910 Insulin signaling pathway
    114197723 (PRKACA)
   04922 Glucagon signaling pathway
    114197723 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    114197723 (PRKACA)
   04912 GnRH signaling pathway
    114197723 (PRKACA)
   04913 Ovarian steroidogenesis
    114197723 (PRKACA)
   04915 Estrogen signaling pathway
    114197723 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    114197723 (PRKACA)
   04921 Oxytocin signaling pathway
    114197723 (PRKACA)
   04926 Relaxin signaling pathway
    114197723 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    114197723 (PRKACA)
   04918 Thyroid hormone synthesis
    114197723 (PRKACA)
   04919 Thyroid hormone signaling pathway
    114197723 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    114197723 (PRKACA)
   04916 Melanogenesis
    114197723 (PRKACA)
   04924 Renin secretion
    114197723 (PRKACA)
   04925 Aldosterone synthesis and secretion
    114197723 (PRKACA)
   04927 Cortisol synthesis and secretion
    114197723 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    114197723 (PRKACA)
   04270 Vascular smooth muscle contraction
    114197723 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    114197723 (PRKACA)
   04971 Gastric acid secretion
    114197723 (PRKACA)
   04976 Bile secretion
    114197723 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    114197723 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    114197723 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    114197723 (PRKACA)
   04727 GABAergic synapse
    114197723 (PRKACA)
   04725 Cholinergic synapse
    114197723 (PRKACA)
   04728 Dopaminergic synapse
    114197723 (PRKACA)
   04726 Serotonergic synapse
    114197723 (PRKACA)
   04720 Long-term potentiation
    114197723 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    114197723 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    114197723 (PRKACA)
   04742 Taste transduction
    114197723 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    114197723 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    114197723 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    114197723 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    114197723 (PRKACA)
   04714 Thermogenesis
    114197723 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114197723 (PRKACA)
   05205 Proteoglycans in cancer
    114197723 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    114197723 (PRKACA)
   05203 Viral carcinogenesis
    114197723 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114197723 (PRKACA)
   05163 Human cytomegalovirus infection
    114197723 (PRKACA)
   05165 Human papillomavirus infection
    114197723 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    114197723 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    114197723 (PRKACA)
   05020 Prion disease
    114197723 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    114197723 (PRKACA)
   05031 Amphetamine addiction
    114197723 (PRKACA)
   05032 Morphine addiction
    114197723 (PRKACA)
   05034 Alcoholism
    114197723 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    114197723 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    114197723 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    114197723 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:eju01001]
    114197723 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:eju03019]
    114197723 (PRKACA)
   03036 Chromosome and associated proteins [BR:eju03036]
    114197723 (PRKACA)
Enzymes [BR:eju01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     114197723 (PRKACA)
Protein kinases [BR:eju01001]
 Serine/threonine kinases: AGC group
  PKA family
   114197723 (PRKACA)
Messenger RNA biogenesis [BR:eju03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     114197723 (PRKACA)
Chromosome and associated proteins [BR:eju03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    114197723 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 114197723
NCBI-ProteinID: XP_027944656
LinkDB
Position
Unknown
AA seq 351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgccgcagccgccaagaagggcagcgagcaggagagcgtgaaagagttctta
gccaaagccaaagaagattttcttaaaaaatgggaaaatcctgctcagaatacagcccat
ttggatcagtttgaacggatcaagaccctcggcacgggctcctttgggcgagtgatgctg
gtgaagcacaaggagaccgggaaccactttgccatgaagatcctcgacaaacagaaggtg
gtgaagctgaaacagatcgagcataccctgaacgaaaagcgcattctgcaagcggtcaac
tttccgttcctcgtcaaactcgagttctccttcaaggacaactcgaatttatacatggtc
atggagtatgtgcctggcggggagatgttctcgcacctgcggcggatcggaaggttcagt
gaaccacatgcccgcttctacgcggcccagatcgtcctgaccttcgagtacctgcactca
cttgacctcatctaccgggacctgaagccggagaacctcctcattgaccagcagggctac
attcaggtgacagacttcggttttgccaagcgtgtaaaaggccgcacctggaccttatgt
gggacccctgagtacctggccccggagatcatcctgagcaaaggctacaacaaggctgtg
gactggtgggccctgggggttctcatctacgagatggctgctggctacccgcccttcttc
gctgaccagcccatccagatctatgagaagattgtctctgggaaggtgcggttcccatcc
cacttcagctctgacctgaaggatctgctgcggaacctgctgcaggtggacctcaccaaa
cgcttcgggaacctcaagaacggggtcaacgacatcaagaaccacaagtggtttgccaca
actgactggatcgccatctaccagaggaaggtggaagctcccttcataccaaagtttaaa
ggccctggggacacgagtaattttgacgactatgaggaggaagagatccgagtctccatc
aatgagaagtgtggcaaggagtttactgagttttag

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