Eumetopias jubatus (Steller sea lion): 114198487
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Entry
114198487 CDS
T07240
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju01521
EGFR tyrosine kinase inhibitor resistance
eju01522
Endocrine resistance
eju01524
Platinum drug resistance
eju04010
MAPK signaling pathway
eju04012
ErbB signaling pathway
eju04020
Calcium signaling pathway
eju04066
HIF-1 signaling pathway
eju04151
PI3K-Akt signaling pathway
eju04510
Focal adhesion
eju04520
Adherens junction
eju04530
Tight junction
eju05200
Pathways in cancer
eju05205
Proteoglycans in cancer
eju05206
MicroRNAs in cancer
eju05212
Pancreatic cancer
eju05213
Endometrial cancer
eju05215
Prostate cancer
eju05219
Bladder cancer
eju05223
Non-small cell lung cancer
eju05224
Breast cancer
eju05226
Gastric cancer
eju05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
114198487 (ERBB2)
04012 ErbB signaling pathway
114198487 (ERBB2)
04066 HIF-1 signaling pathway
114198487 (ERBB2)
04020 Calcium signaling pathway
114198487 (ERBB2)
04151 PI3K-Akt signaling pathway
114198487 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
114198487 (ERBB2)
04520 Adherens junction
114198487 (ERBB2)
04530 Tight junction
114198487 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114198487 (ERBB2)
05206 MicroRNAs in cancer
114198487 (ERBB2)
05205 Proteoglycans in cancer
114198487 (ERBB2)
05230 Central carbon metabolism in cancer
114198487 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
114198487 (ERBB2)
05226 Gastric cancer
114198487 (ERBB2)
05219 Bladder cancer
114198487 (ERBB2)
05215 Prostate cancer
114198487 (ERBB2)
05213 Endometrial cancer
114198487 (ERBB2)
05224 Breast cancer
114198487 (ERBB2)
05223 Non-small cell lung cancer
114198487 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
114198487 (ERBB2)
01524 Platinum drug resistance
114198487 (ERBB2)
01522 Endocrine resistance
114198487 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eju01001
]
114198487 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
eju04147
]
114198487 (ERBB2)
04090 CD molecules [BR:
eju04090
]
114198487 (ERBB2)
Enzymes [BR:
eju01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
114198487 (ERBB2)
Protein kinases [BR:
eju01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
114198487 (ERBB2)
Exosome [BR:
eju04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
114198487 (ERBB2)
CD molecules [BR:
eju04090
]
Proteins
114198487 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
114198487
NCBI-ProteinID:
XP_027945721
LinkDB
All DBs
Position
Unknown
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGAAGTQVCTGTDMKLRLPASPETHLDLLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
EPPEGGASAAGAAPGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LTLIDTNRSRACQPCSPACKDPHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKVFGSLAFLPESFEGDPASNTAPLQAEQLRVFEALEEITGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNTRLCFIHTV
PWDQLFRNPHQALLYSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVMQGLPREYVKDRYCLPCHSECRPQNGSVTCFGAEADQCVACAHYKDPPFCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDERGCPAEQRASPVTSIIAAVVG
ILLAVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGPAHHRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGASKGLHSLPPQDPNPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVWPQPPSPLEGPLPPSRPDGATLERPKTLSPKTLSPGKNGVVKDVFAFGSAVENPE
YLAPRGRAPPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctccggagcc
gcgggcacccaagtgtgcactggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggatctgctccgccacctctaccaggcctgtcaagtggtacagggtaacctg
gagctcacctacctgcctgccaatgccagcctgtccttcctgcaggatatccaggaggtg
cagggctacgtgctcattgctcacagccaagtgagacaggtcccgctgcagaggctccga
atcgtgcgaggcacccagctctttgaggacaactacgccctggccgtgctggacaatgga
gagccgcccgaggggggcgcctctgcggcaggggctgccccaggagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggaggggtgttgattcagcggaacccacag
ctctgccaccaggacacgattttgtggaaggacatcttccacaagaacaaccagcttgcg
ctcacgctgatagacaccaaccgctctcgggcctgccaaccctgttctccagcttgtaaa
gacccccactgctggggagcaagttccggggactgtcagagcttgacgcgaacggtctgt
gccggcggctgtgcccgctgcaaaggtccgaagcccaccgactgctgccatgagcagtgt
gcggctggctgcacaggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacggacaccttcgaa
tccatgcccaaccccgagggccgatacaccttcggggccagctgtgtgaccgcctgtcca
tacaactacctgtctacggacgtgggctcctgcactctggtctgtcccctgaacaaccaa
gaggtgacggctgaggacggaacacagcggtgtgagaagtgcagcaagccctgtgcccga
gtgtgctacggcctgggcatggagcacctgcgggaggtgagggcggtcaccagtgccaac
atccaagagtttgccggctgcaagaaggtctttgggagcctggcgtttctgccagagagc
tttgagggagacccagcctccaacactgcccccctccaggctgagcagctcagagtgttt
gaggctctggaggagatcacaggttacctgtatatctcagcgtggccagacagcctgcct
aacctcagtgtcttccagaacctgcgagtcatccggggacgagttctgcatgacggcgcc
tactcgctgaccctgcaagggctgggcatcagctggctggggctgcgctcactgagggaa
ctgggcagtgggctggccctcatccatcgcaacacccgcctctgcttcatacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctctacagtgccaaccggccg
gaggccgagtgtgtgggcgagggcctggcctgctacccgctgtgcgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgc
gtggaggaatgccgagtaatgcaggggctaccccgggaatatgtgaaggacaggtactgt
ctgccatgtcactccgagtgccggccccagaatggctcagtgacctgctttggggcggaa
gctgaccagtgtgtggcctgtgcccactacaaggaccctcccttctgcgtggctcgctgc
cccagtggtgtgaaacccgacctctccttcatgcccatttggaagtttgcagatgaggag
ggcacgtgccagccgtgtcccatcaactgcacccactcctgtgcagacctggacgagagg
ggctgccccgccgagcagagagccagccctgtgacatccatcattgccgctgtggtgggc
attctgctggctgtggtcgtggggctagtcctcggcatcctaatcaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggaaaccgagctggtggagccactg
acgcctagcggagcgatgcccaaccaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcacagtctacaagggcatctggatc
cctgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggatgaagcatacgtgatggctggcgtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtaacacagctt
atgccctacggctgcctcttagaccatgtccgagagcaccgcgggcgcctaggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggacgttcgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtcaag
attacagacttcgggctggctcggttgttggacattgatgagaccgagtaccacgcggat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
caccagagcgatgtgtggagctacggtgtgactgtgtgggaactgatgacttttggagcc
aaaccttatgatgggatcccagcccgggagatccctgacctgctggagaagggggagcgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
atagactctgaatgtcgaccacggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaagacttgggccccgccagcccgttg
gacagcaccttctaccgttcgctgctggaagatgatgacatgggggacctggtggatgct
gaggagtacctggtaccccagcaggggttcttctgcccagaccctgccccaggtgctggg
ggcccggcccaccacaggcaccgcagctcatccaccaggagtggcggcggtgagctgaca
ttgggactggagccctctgaggaggagccccccaagtctccactggcaccctcagagggg
gctggctctgacgtgtttgatggcgacttgggaatgggggcatccaaggggctgcatagc
cttccgccacaggaccccaatcctctacagcggtacagcgaggaccctacagtacccctg
ccccctgagactgatggctacgttgcccccttgacctgcagtcctcagcctgaatacgtg
aatcagccagaggtttggccacagcccccctcgcccctagaaggccctctgcctccttct
cgacctgacggtgccactctggaaaggcccaagactctgtcccccaagactctctcccct
ggcaagaatggggttgttaaagacgtttttgcctttgggagtgctgtggagaaccctgag
tacttggcaccccggggcagggctccccctcagccccaccctcctccagccttcagccca
gcatttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagc
acctttgaagggacccctacagcagagaaccctgagtacctgggcctggacgtgccagtg
tga
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integrated database retrieval system
