Eumetopias jubatus (Steller sea lion): 114198830
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Entry
114198830 CDS
T07240
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
114198830 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
eju03021
]
114198830 (SETX)
Enzymes [BR:
eju01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
114198830 (SETX)
5.6.2.5 RNA 5'-3' helicase
114198830 (SETX)
Transcription machinery [BR:
eju03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
114198830 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
nSTAND3
AAA_22
ResIII
SLFN-g3_helicase
NAT10_TcmA_helicase
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
114198830
NCBI-ProteinID:
XP_027946288
LinkDB
All DBs
Position
Unknown
AA seq
2692 aa
AA seq
DB search
MSTCCWCTPGGISTVDFLQRYASETHSSEFQTADEDLCYCLECVAEYHKARDDLPFLHEV
LWELETLRLINYFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQADDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEAFQTIINNVSYNKEIQNIRNSSVRTKLEPESYLDDATCSQIVYNYNP
EKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMDL
KDLGVAYIVEVIHHLHSEVKDVLNQTDAMCDKVTEFFLLILVSVIELHRNKKCLHLLWVS
SQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLACVQLIRS
LLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIKNIKVKVPQ
CNTFVDLSPAGKSSPASYSKEESEQIERRSNKDLHCLENSSPTFSKEPMKAEAYQIQENI
LIKASNTIEEDNEQNYIKDWKLEDHLSAESCIKKSSKNVFTERAQDQVKISTGKQKSVKE
NCTSRNVLQNCTSRNGPERGCDRGIIMSTRLLTDSSTDSLEKACTSNEDLSFKDDALGKT
AKSKTKAHKDEICAKLSHVIKKQHRKSTLINNTGNLEENLTVSNIDSFYSRKDSGGQKGD
GFMHNLSLDPLGILDEKNGEQKSQKSLLLKKKQLKSEELEIFSSHENSYQIQECHDDKDL
VSFTEVTNTFVRKTSPFKDPVTVLESKDKEISKNTSQMSSHLREQAPGLSPQSDTLTDSQ
IDRDLHKLSLIAQASVIKFPSDSTQKSSSQLQRRVKDDRRCFPADQNNTGEACRGQIIII
SDSDDDNDDDEGILGLEKRIKQDKIGIKKECPEQHTSIASTNVEKKLIKEEETKSLLQFE
ESDSQFFEFESPCEVFSVWQDQEPDKNSVQESEKNSCSTDIADITNDWGYETDYVSEEVI
KKVAEGIEKHTEPQGSISVGEFCEIEVKKRKRKRFEKPMAEGPLRPSPSDRNEDQPDILN
ERGLTENDFKSMDLRTVSPTSGVQRDKDTTVSLKKSSPKLRTYSKPIRRVPLSKTPKKTH
SDTKKGQNKSSNYISCRTTPAIVPPKKFRQCPEPTLTVEKLGLKKAPRRAFELSQRSLEC
LVRLRHHGKTVGVVDTSKKTKLISPQTLSVRNNKKLLTSQDLQLRRQMRPKSQQNRQGLL
DYENKDTTRAGLCTAQNSDIPVPESDGSDYSYKGGTEVVANSTGKQTKCVSSEPEPMKTK
YVSQVTNDACLLNQSAAVVLNGRIPTNEIIVSASADPLGGGDRTVHHLELATLKDGEPES
NSDTEDENIFLTQHDPEDMDLCSQMENGNEKLIEVVHGKDTAQVEEDSVSQPQLESWNST
KCKYKDCVETPKNQGDYCSKHCEAKAADEDVFRKPGLPLSASKPSRPSTAKIFSSSSTSR
IANLSKSLESTSALPPALKNKSNGAQAVLKVPQPASLVSPKPGGEVKSLGNVFHPQTPSN
SSRQGYKLTFGESKSFSASSPVHILLSSQSISDTFVKEVLKWKYEMFVNFDQCGPPASLC
QSISRPVPVRFQDCGDYFNVFFPLMVLNTFETVAQEWISSPNKEKFYQLHLRKFPADYKK
YWEFVVHLEECELAKQVHPKENDLVFLVPERQNGEKKDTERNRMQDLREYHCGYIHKFRR
TSVMRNGKSECSLSIQTQDNLPVNLNELVKCVVISSLVTTQRKLKAMSLLSGRNQLARAV
LNPNPMDFCTKDLLTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPG
TGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKE
KCKDKKNPLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQEMHRRKEF
LDHQLDELSRQRALCRGGREIQRQELDEKIAKVSKERQELASKIKEVQGRPQKTQSIIIL
ESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVG
DPKQLPPTVISMKAQEYGYDQSMMARFYKLLEDNVEHNMIGRLPILQLTVQYRMHPDICL
FPSNYVYNRSLKTNRQTETNRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIKLVMEI
IKLIKDKRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDKKGPAEVDTVDGFQGRQKDCVI
VTCVRANTMQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGA
IIKTCDKNYRHDAAKILKLKPVLQRSLTHPPAVAPEASRPQGGLPSNKLDSEFAKTSFTS
SLYHTPPDSKESSGTVTTKDPERPLVQDRLRDPRLLRRMGLDPEAKGMCLRDPQPLSPQH
PGATPPSGEPGFPASHQDLGGAQQSAARGTALNNHEPHAQCEPPAAGTGVSTSKSRCDWE
GGLSHRRETRAFSEGDRGRWSPESHYSKRSPGWDRTGPQKEGCSSKRRRLLW
NT seq
8079 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgccaggtggcatttccaccgttgacttcctacagcgc
tatgcatccgagacccactccagtgagtttcaaacagctgatgaagacctctgctactgc
ttagagtgtgtggccgaataccacaaagcaagggatgatttaccattcttgcatgaggtt
ttatgggaattagaaaccttacgtctcataaattactttgaaaaatccatgaaggcagaa
attggagatgatgatgaattgtatatagtagacaacaacggagaggcacaactgtttgac
tttaccggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatctgcttttacatgagcgtgttaatgaattatgtgttgaagcactttgtcggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccaggcatctatttgtttctg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaagaaatttgggaaaa
gtggacagagatgattattatgacttgcaggaggttttgacttgcctttttaaagtcatt
gaattggggcttttggaaagtccagacatttatacttcttctgttctcgagaagggtaaa
ctgattcttctgccctcacacatgtacgataccaccaactacaaaaactattggttaggt
atttgcatgttgctgaccattctggaggagcaggccatggactcactattgctgggctca
gacaaacagaatgattttatgcaatcaatacttcacaccatggagaggcaagcagatgat
gatagtgtggatcctttttggccagccttacactgtttcatggtgattctggatcgcctt
ggatctaaggtctggggtcaacgtattgatcctattgaggcatttcagaccattatcaac
aatgtgagctacaataaagagatccaaaatatacggaacagctctgtaaggaccaagtta
gaaccggaatcatatttggatgatgcgacttgcagccagattgtatacaattataatccc
gaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattattgtcctaac
atgtatgaagagatggaaacattagccagtgtgcttcagtcagatattggtcaagacatg
cgtgttcataacagcacctttctgtggttcatcccttttgttcagtccctcatggatctt
aaggatttgggtgtggcttatatagtagaggttattcatcatctgcactccgaagtcaag
gatgtcctcaaccaaacagatgccatgtgtgacaaagttactgaattttttcttctgatt
ttggtgtccgtgattgagctgcatagaaataaaaaatgtctgcatttgctgtgggttagt
tcccagcaatgggtagaagccgttgtaaaatgtgccaagctacctaccactgcatttgca
cggagttctgagaagtcatctggaaattgctctaaaggaacagcaatgatatcgtctctg
tcattgcattcaatgccatcaaattctgtacaactggcttgtgtgcagctgattagaagt
ctccttaaagaaggttatcagcttgggcagcaaactttatgtaagcgattctgggataaa
ctcaatttatttctgcgtggaaatttatctctaggttggcagttgactactcaggaaacc
catgagttacaaacttgtttaaagcaaattattaaaaacataaaagtcaaagtacctcaa
tgtaacacttttgtggatttgagtcctgcaggtaaaagctctccggcatcttacagtaaa
gaagaaagtgaacaaatagagaggagatccaataaagatctgcactgtctggaaaactcc
agcccaacattttctaaagaaccaatgaaagctgaggcatatcaaatacaagagaatata
ttgattaaagcaagcaacactatagaagaggataatgagcaaaattatataaaagattgg
aaactagaagatcatctctcagccgagtcatgcataaagaagagtagtaaaaacgttttc
actgaaagagctcaagatcaagttaaaataagtacagggaagcagaagtccgtgaaagag
aattgtacttcaagaaatgtactgcagaattgtacttcaaggaatggtccagaaagggga
tgtgacagaggaataataatgtcaacacgtttgttgactgactctagcactgattctctg
gagaaggcatgcacatcaaatgaggatttatctttcaaggatgatgctcttggcaaaacc
gcaaaatcaaaaactaaggcacataaagatgaaatctgtgctaagttatcacatgtaata
aagaagcaacacaggaaaagtactttgatcaataatactggtaatttagaggaaaaccta
actgtgtctaacattgacagtttctattcaaggaaagattcaggaggtcagaaaggggat
ggcttcatgcacaatctctctttagaccctctcggcattctggatgaaaaaaatggggaa
caaaaatctcaaaagagtttattgctgaaaaagaaacaactgaagagtgaagagttagag
attttctcttcccatgaaaacagctatcaaatacaggaatgtcacgatgataaagatttg
gtctcatttacggaagtgaccaacactttcgtgaggaaaacgtctcccttcaaagatcct
gtgactgttcttgaatcaaaagataaggaaattagcaagaataccagtcagatgtcttct
cacttgagagaacaagctcctggcctcagtcctcagtctgacaccttaacagattctcag
atagacagagacctccacaagttatctttaatagctcaagccagcgttattaagttccca
tcagattcaactcaaaaaagctcatcccagctacaaaggagagtgaaagacgacagaaga
tgtttcccggctgaccagaataatactggggaagcctgtcggggccagattattattatt
tcagattctgatgatgataatgatgatgatgaaggaattctaggtttggagaaacgtatt
aaacaagataaaataggcatcaagaaagaatgcccagagcagcatacttcaatagctagt
acgaatgtggaaaagaagttaataaaggaagaggagacaaagtcccttttgcagtttgag
gaatcagattctcagttttttgagtttgaaagtccatgtgaagtgttttcagtttggcaa
gatcaggaaccagacaagaattcagttcaagaaagtgaaaaaaactcttgttcgactgac
atagctgatatcacgaatgattggggttatgagacagattatgtatctgaagaggttatt
aagaaggtagcagagggcattgaaaaacacacagagccacagggtagtatttctgttggg
gaattctgtgaaattgaagtaaaaaaacgtaagagaaaacgatttgaaaaacctatggct
gaaggtcctctaaggccttcaccttctgatagaaatgaggaccagcctgatattcttaat
gagagaggtctgactgaaaatgattttaaaagtatggacctaaggacagtgagtcccact
tcaggtgttcagagagacaaagacactacggtttcactaaagaagtcttctccaaagctt
cgtacttactccaaacccattagaagagtcccactttctaaaactcctaagaaaacacat
tcagataccaagaaagggcagaacaaaagttcaaattatataagttgtaggacaactcct
gctatagttccaccaaagaaatttcgccagtgccctgaaccaactttaacagttgagaaa
cttggtctgaagaaggctcctcgtagggcatttgagttgtctcagcgatctctagagtgt
ttagttcggttacgccaccatggcaaaactgttggagtggttgatactagcaaaaagact
aagttaatttctcctcagactctctctgtcagaaacaataagaaactgctgacaagtcaa
gatcttcagttgcgaaggcagatgagacccaaatcacaacaaaatagacaaggacttctg
gattatgaaaataaagatactacaagagcagggctgtgtacagcacaaaattctgacata
cctgtcccagaatcagatggttcagattatagttacaaaggaggaactgaggtggttgct
aacagcactgggaaacaaacaaaatgtgtgtcttcggaaccagaacccatgaaaacaaaa
tatgtgtctcaggtgaccaatgatgcttgtcttttgaaccagtctgctgctgttgtattg
aatggaagaataccaacaaatgaaatcattgtctctgcttcggcagaccccttaggcggt
ggtgaccgaacggtacatcatttagagttggcaactttgaaagacggagagcctgaatcc
aacagtgatacagaagatgagaatatatttctaacacagcacgatcctgaagatatggat
ttgtgttcacagatggagaatggtaatgagaaactcattgaagtagttcatggcaaagat
acagctcaggtggaagaagattctgtaagtcagcctcagttggaatcttggaatagcaca
aaatgtaagtacaaagattgtgttgaaaccccaaaaaaccagggtgactactgctcaaaa
cactgtgaagctaaagcagcagatgaagatgtatttcgtaaacctggcttgcccctttct
gcatctaagccttccagaccttccactgcgaagatttttagctcaagtagtacttcacga
attgctaacctttccaagtctttggaaagtacctctgcacttccaccagctctaaaaaat
aagtcaaatggggcacaggctgttttgaaagtcccacagccagcctctctggtgtctcca
aagccagggggtgaagtgaagagtttgggcaatgtttttcatccccagactccaagtaat
tccagcaggcaaggttacaaactgacgtttggtgaaagcaaatccttctcggcttcctct
ccagtccacattctcttgtcatcacagtccatctctgacacttttgtcaaagaggtctta
aaatggaaatacgaaatgtttgtgaactttgatcagtgcgggcccccagcaagcctttgt
cagtccatctcgagacctgtgcctgtcagatttcaagattgtggagattattttaatgtt
tttttccctttgatggtattgaatacttttgaaacagtggcacaggagtggatcagctct
ccaaacaaagagaaattctatcagttgcatttacgaaaatttcctgctgattataaaaaa
tactgggagtttgtggttcatcttgaggaatgtgaactagctaaacaggttcatccaaag
gaaaatgatttggtgtttttggttcctgaaagacaaaatggagagaagaaagatacagag
agaaatcgcatgcaagatctccgtgaatatcattgtggttatattcataagtttcgccgc
acttcagtcatgcgcaatgggaaatctgagtgttccctttccatccagactcaagataat
ttaccagtcaatttaaatgaactcgtgaaatgcgttgtaatcagttctctggtaactaca
caaaggaagttgaaagccatgtctttgttgagtggacggaaccaactggccagagctgtt
ctgaatccaaaccccatggacttctgtacaaaagatttactaactacaacatctgagaga
attatcgcctacttaagagatttcaacgaagaccaaaagaaagcgatagaaactgcatat
gccatggtcaaacactccccgtcagttgccaagatctgtctgattcatggaccacctgga
acaggaaaatcaaaaactattgttggcctcctgtaccgcctcctgacagagaaccagagg
aaggggcattcagatgaaaactccaatgccaaaatcaaacaaaaccgtgtccttgtgtgt
gcgccttccaacgcagctgttgatgaacttatgaaaaaaatcatcctcgaatttaaagaa
aaatgtaaagacaagaagaatcctttgggaaactgtggagatataaatttagtacgtctc
ggtccagaaaagtctattaataatgaggtcctaaaattcagtttggacagccaagttaac
cacagaatgaaaaaagacttaccttctcatgttcaggagatgcatagaagaaaggaattt
ctagatcaccaacttgatgaactttcccgccagcgtgctttatgccgaggtggaagggaa
atacagaggcaagaattagatgaaaaaattgcgaaagtttcaaaagagaggcaggaacta
gcttctaaaattaaagaggttcaaggacgcccacaaaaaacacagagcatcatcatctta
gagtctcatgtcatctgctgcacattgagcacgagtggtggtttactgcttgagtctgct
tttcgtgggcaagggggtgtccccttcagttgtgtcattgtcgatgaggccgggcagtct
tgtgaggttgagactcttactccactcatccatcgttgtaacaagctcatcctcgtagga
gatcctaaacagctccctcccacggtcatttctatgaaagcacaggaatatggctatgac
cagtcaatgatggcgcgcttctacaagctgctggaagacaacgtggagcacaatatgatc
ggcaggctgcctattttacagcttactgttcagtacaggatgcacccagacatatgtctc
ttcccctctaactatgtttataacagaagcttgaaaacaaatagacagactgaaaccaat
cggtgttcatcagactggccatttcaaccttacctggtgtttgatgtcggagacggctca
gaaagacgggataatgactcatatgtaaatgttcaagaaataaaactggtaatggaaata
attaaacttattaaagacaaaagaagggatgttactttccggaacattggcataataacc
cattacaaggctcagaagacgatgattcagaaggatttggacaaagaatttgataaaaaa
gggccagcggaagtagataccgtggatgggttccagggccggcagaaggattgcgttatt
gttacgtgcgtcagagcaaataccatgcagggctcaattggatttctggcaagtttgcag
agactgaacgtcaccatcacacgagccaagtacagcctcttcatcctcggacatttaagg
accctcatggaaaatcagcactggaaccacctgattcaggatgcacagaagcggggcgcc
atcatcaagacgtgcgacaagaactacaggcacgacgcagcgaagattctgaagctcaag
cccgtgctgcagagaagtctgactcacccgccagccgtagccccggaggcgtccagaccc
cagggcggcttgcccagcaacaagctcgacagtgaatttgccaagacatctttcacttct
tccctgtatcacacgccccctgactccaaggaatcttctggtactgtcactacaaaggac
cccgaaaggcctctcgttcaggaccggcttcgggacccacgactgctcaggaggatgggc
ctggaccccgaagccaaagggatgtgcctaagggatccgcagcccctgagcccgcagcac
cccggagcgacacctccctcgggcgagccaggcttccctgccagtcaccaggatctgggt
ggcgcacagcagtccgctgccagaggaacggctctgaacaaccacgaacctcacgcgcag
tgtgaacctccagctgctgggactggtgtctccacaagtaaaagcagatgtgactgggaa
ggagggctcagccacagaagagagacccgggctttcagtgagggcgaccggggcaggtgg
agcccggagagccactactcgaagaggagccccggctgggacaggacgggaccgcagaag
gagggctgcagctcaaagagaagaaggctcttatggtaa
DBGET
integrated database retrieval system
