KEGG   Eumetopias jubatus (Steller sea lion): 114200595
Entry
114200595         CDS       T07240                                 
Symbol
ITGA2B
Name
(RefSeq) integrin alpha-IIb isoform X1
  KO
K06476  integrin alpha 2B
Organism
eju  Eumetopias jubatus (Steller sea lion)
Pathway
eju04015  Rap1 signaling pathway
eju04151  PI3K-Akt signaling pathway
eju04510  Focal adhesion
eju04512  ECM-receptor interaction
eju04518  Integrin signaling
eju04611  Platelet activation
eju04613  Neutrophil extracellular trap formation
eju04640  Hematopoietic cell lineage
eju04810  Regulation of actin cytoskeleton
eju04820  Cytoskeleton in muscle cells
eju05165  Human papillomavirus infection
eju05200  Pathways in cancer
eju05222  Small cell lung cancer
eju05410  Hypertrophic cardiomyopathy
eju05412  Arrhythmogenic right ventricular cardiomyopathy
eju05414  Dilated cardiomyopathy
eju05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eju00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    114200595 (ITGA2B)
   04151 PI3K-Akt signaling pathway
    114200595 (ITGA2B)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    114200595 (ITGA2B)
   04518 Integrin signaling
    114200595 (ITGA2B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114200595 (ITGA2B)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    114200595 (ITGA2B)
   04810 Regulation of actin cytoskeleton
    114200595 (ITGA2B)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    114200595 (ITGA2B)
   04611 Platelet activation
    114200595 (ITGA2B)
   04613 Neutrophil extracellular trap formation
    114200595 (ITGA2B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114200595 (ITGA2B)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    114200595 (ITGA2B)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    114200595 (ITGA2B)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    114200595 (ITGA2B)
   05410 Hypertrophic cardiomyopathy
    114200595 (ITGA2B)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    114200595 (ITGA2B)
   05414 Dilated cardiomyopathy
    114200595 (ITGA2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:eju01009]
    114200595 (ITGA2B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:eju04147]
    114200595 (ITGA2B)
   04515 Cell adhesion molecules [BR:eju04515]
    114200595 (ITGA2B)
   04090 CD molecules [BR:eju04090]
    114200595 (ITGA2B)
Protein phosphatases and associated proteins [BR:eju01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     114200595 (ITGA2B)
Exosome [BR:eju04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   114200595 (ITGA2B)
Cell adhesion molecules [BR:eju04515]
 Integrins
  Integrin alpha subunits
   114200595 (ITGA2B)
CD molecules [BR:eju04090]
 Proteins
  114200595 (ITGA2B)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_2 Integrin_A_Ig_1 FG-GAP FG-GAP_3 Integrin_alpha
Other DBs
NCBI-GeneID: 114200595
NCBI-ProteinID: XP_027948599
LinkDB
Position
Unknown
AA seq 1080 aa
MALSSAYCSASGFQFDKKSLPVVETERKRKELTHSCLGGCGRRKMARAVCPLHALWLLEW
VQLLLGPGPIPPAWALNLDPVQLTLYTGPNGSHFGFSLDFYKDNHGRVAIVVGAPRTLGP
SQEETGGVFLCPWRAEGSQCTLLTFDLNDETRHVGSHTFQTFKSRQGLGASVVSWNDNIV
ACAPWQHWNALEKTEEAEKTPVGGCFVAQLQNGHRAEYSPCRANTMSQVYVKNGFIDDRR
YCEAGFSSVVTQAGELVLGAPGGYFFLGLLARAPITSIVSSYRPGTLLWHVPNQSFTLDY
SKPEYYDGYRGYSVAVGEFDGDLNTTEYVLGAPTWSWTLGAVEILNSSHQTLHKLHGEQM
ASYFGHSVTVTDVNGDGRHDLLVGAPLYMESRAGRKLAEVGRVYLFLQPRGHHVLGAPSL
LLTGTQLYGRFGSAIAPLGDLDRDGYNDVAVAAPYGGPSGRGQVLVFLGQSEGLSSRPSQ
ILDSPFPAGSGFGFSLRGATDIDDNGYPDLLVGAYGANKVAVYRAQPVVMANVQLLVQDS
LNPAVKNCVLPQTQTRVTCFNIQMCVGATGHNIPQQLPLNAELQLDRQKPRQGRRVLLLN
SQLSGTTLHLDLGGRHSPICHTTVAFLRDEADFRDKLSPIVLSFNVSLQTRKDGVAPAVV
LHGDTHVQEQTRIILDCGEDDLCVPQLQLTVNVMGSPLLIGADNVLELQMAAANEGEGAY
EAELAVHLPLGAHYMRAISNIEGFERLICNQKKENETKMVLCELGNPMKRNARIGITMLV
SVENLEEAGERVSFWLQIRSKNSQNPNSEAVLLDVPVRAEAHVELRGNSFPASLVVVAEE
DNRENSSDIWGPKVEHTYELHNNGPGTVSGLRLCLCLPGQSQPSDLLYILDIQPQGGLQC
SPQPTPNPYKLNWRLPTPSPSTTSLGHHKRERRQASLSGSNQPARLQDPVLLSCDSGPYT
VVQCELQEMERGQRAMVRVLAFLQLPGLQQRPLDQFVLQSQAWFNVSSLPYAVPALSLPS
GETLVQTHLLRALEERDIPIWWVLVGVLGGLVLLMLLVLAMWKVGFFKRNRPPLEEDEEE
NT seq 3243 nt   +upstreamnt  +downstreamnt
atggctctttcctctgcctactgctcagcaagtgggttccagtttgataagaaaagcctt
cccgtggtagaaactgaaaggaagaggaaggagctcacccattcctgcctaggaggttgt
gggagaaggaagatggccagagctgtgtgtccacttcatgccctctggcttctggagtgg
gtgcagctgctcttgggacctggtcccatccctccagcctgggccttgaacctggaccca
gtgcaactcaccttgtacacgggccccaatggcagccactttgggttttcactggacttc
tacaaggacaaccatgggagagtggccatcgtggtgggcgccccgcggaccctgggccca
agccaggaggagacaggcggcgtgttcctgtgcccgtggagggcggagggcagccagtgc
accttgctgaccttcgacctcaatgatgagacccgacacgtaggctcccacaccttccaa
accttcaagtcccggcaaggactgggggcgtcggtcgtcagctggaacgacaacattgtg
gcctgcgccccctggcagcactggaacgccctagaaaagaccgaagaagctgagaagacg
cccgtaggtggctgcttcgtggctcagctacagaacggccaccgcgcagagtactcgccc
tgtcgggctaacaccatgagccaggtttacgtgaaaaacggctttatagacgaccggcgc
tactgcgaagcgggcttcagctccgtggttactcaggctggagagctggtgcttggggcc
cctggcggctattttttcttaggtctcctggcgcgggctcccattaccagtatcgtctcg
agttaccgcccaggcaccctcttgtggcacgtgcccaaccagagcttcaccttagactac
agcaagccagagtactacgacggctaccgggggtactcggtggccgtgggagagttcgac
ggggatctcaatactacagagtatgtcctcggtgcccccacctggagctggaccctggga
gcggtggaaattttgaactcctcccaccagacgctgcacaagctgcatggagagcagatg
gcttcgtattttggacactcggtgaccgtcactgatgtcaacggagacgggaggcacgac
ctgctggtgggcgcgccactgtacatggagagccgcgctggccgcaagctggccgaggtg
gggcgcgtgtacttgttcctgcagcctcgaggccaccacgtgctgggcgcccccagcctc
ctgctgaccggcacacagctctacgggcggttcggctcggccatcgcacctctgggcgac
ctcgaccgggacggttacaacgatgttgcagtggccgccccatatggaggtcccagtggt
cggggccaagtgctggtgttcctggggcagagcgaggggctgagctcacgcccctcccag
atcctggacagccccttcccagcaggctctggcttcggcttctccctgcgaggtgccacc
gacatcgatgacaatggatacccagacctcctggtgggagcttatggggccaacaaggtg
gctgtgtacagagctcagccagtggtgatggccaatgtccagctgctggtgcaagattca
ctgaatcctgctgtgaagaattgtgtcctgccccagacccagacgcgcgtgacctgcttt
aacatacagatgtgtgtaggagccactgggcacaacattcctcagcagctgcccctaaat
gccgagctgcagctggaccggcagaagccccgccagggccggcgggtgctactgctgaat
tcgcaattgtcaggcaccacgctgcatctggacctgggcgggaggcacagccccatctgc
cacaccaccgtggctttcctccgagacgaggccgacttccgggacaagctgagccccatt
gtgctcagcttcaatgtgtccttgcaaaccaggaaggatggagtagcccctgctgtcgtg
cttcatggagacacccatgtccaggagcagacccgcatcatcctggactgtggggaagat
gacctgtgcgtgccccagctccagctcaccgtcaacgtgatgggctcccccctcctcatt
ggagccgataatgtgctggagctgcagatggctgcagccaacgagggcgagggggcctac
gaagcagagctggccgtgcacctgcccctaggcgcccactatatgcgggccatcagcaac
atcgagggctttgagagactcatctgtaaccagaagaaggagaatgagaccaagatggtg
ctgtgtgagctgggcaaccccatgaagaggaatgcccggataggaatcacgatgttggtg
agtgtggagaacctggaagaggctggggagcgtgtgtccttctggctacagatcagaagc
aagaacagccagaatccgaacagtgaggctgtgctgctggatgtcccagtccgggcagag
gcccatgtggagctgcgagggaactcctttccagcctccctggtggtggtggccgaagaa
gacaacagggagaacagctccgacatctggggccccaaagtggagcacacctatgagctc
cacaacaatggccctggcactgtaagtggcctccgcctctgcctctgcctccctggccag
tcccagccttctgacctgctctacatcctggacatacagccccagggggggcttcagtgc
tccccccagcccactcctaacccctacaagctgaactggaggctgccgacccccagcccc
tccaccacctccctcgggcatcacaagcgggagcgcagacaggcgtccctgtcagggtcc
aaccagccagccaggctgcaggatccagttctcctgagctgtgactcggggccgtacacg
gtggtgcagtgtgagctgcaggagatggagcgaggccagcgggccatggtcagggtgctg
gccttcctgcagctgcccggcctccagcagaggccactggatcagttcgtgctgcagtcg
caagcttggttcaacgtctcctcccttccctacgccgtgcccgccctcagcctgcccagt
ggggaaactctggtgcagacgcacctgcttcgagccttggaggaaagggacattcccatc
tggtgggtgctggtaggcgtgctcggcggcctggtgttgctcatgctcctggtcctggcc
atgtggaaggtcggcttcttcaagcgcaaccggccgccactagaagaagatgaggaggag
tag

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