KEGG   Eumetopias jubatus (Steller sea lion): 114201903
Entry
114201903         CDS       T07240                                 
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1
  KO
K02599  Notch 1
Organism
eju  Eumetopias jubatus (Steller sea lion)
Pathway
eju01522  Endocrine resistance
eju04330  Notch signaling pathway
eju04658  Th1 and Th2 cell differentiation
eju04919  Thyroid hormone signaling pathway
eju05020  Prion disease
eju05165  Human papillomavirus infection
eju05200  Pathways in cancer
eju05206  MicroRNAs in cancer
eju05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:eju00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    114201903 (NOTCH1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    114201903 (NOTCH1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    114201903 (NOTCH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114201903 (NOTCH1)
   05206 MicroRNAs in cancer
    114201903 (NOTCH1)
  09162 Cancer: specific types
   05224 Breast cancer
    114201903 (NOTCH1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    114201903 (NOTCH1)
  09164 Neurodegenerative disease
   05020 Prion disease
    114201903 (NOTCH1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    114201903 (NOTCH1)
SSDB
Motif
Pfam: EGF hEGF EGF_TEN EGF_CA EGF_2 Ank_2 Ank Notch NOD NODP Ank_5 Ank_4 Ank_3 EGF_3 Gurken_M JAG1-like_EGF2
Other DBs
NCBI-GeneID: 114201903
NCBI-ProteinID: XP_027950669
LinkDB
Position
Unknown
AA seq 2567 aa
MPPLLAPLLCLALLPALAARGLRCSQPSESCLNGGKCEVFPNGTEACVCSGAFVGQRCQA
PSPCLSAPCKNAGTCHVVDRGGLVDYACTCRLGFSGPLCLTPQDNACLSTPCRNGGTCDL
LTLTEYKCRCPPGWSGKTCQQADPCASNPCANGGQCLPFEASYICGCPPGFHGPTCRQDV
NECSQNPRLCQNGGTCHNEVGSYRCTCRTTHTGPHCELPYVPCSPSPCQNGGTCRPTGDT
THECACLPGFTGQNCEENVDDCPSNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDEC
QLMPNACQNGGTCHNSHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC
ECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLG
ANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICM
PGYEGVHCEVNTDECASSPCLQNGRCLDKINEFLCECSTGFTGHLCQYDVDECASTPCKN
GAKCLDGPNTYTCVCTEGYTGPHCEVDIDECDPDPCHYGVCKDGVATFTCLCRPGYTGHH
CESNINECHSQPCRHGGTCQDRDNAYLCSCLKGTTGPNCETNLDDCVSSPCDSGTCLDKI
DGYECACEPGYTGSMCNVNIDECAGNPCHHGGTCEDGVNSFTCRCPEGYHGPTCLSEVNE
CSSDPCIHGACRDSLNGYKCDCDPGWSGANCDVNNDECESNPCANGGACRDMTSGYVCTC
REGFSGPNCQTNINECASNPCLNQGSCIDDVAGYKCNCPLPYTGATCEVVLAPCAPGPCR
NGGVCKESEDYESFSCICPTGWQGQTCEVDINECVKSPCRNGASCQNTNGGYRCRCRAGY
TGHNCETDVDDCWPNPCHNGGSCTDGINTAFCDCLPGFRGAFCEEDINECASNPCRHGAN
CTDCVDSYTCTCPTGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQ
HDINECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQSLVRWCDSSPCKNGGRCWQTNT
RYRCECHSGWTGLYCDVPNVSCEVAAQRQDINVTHLCRNGGLCMDAGNTHHCRCQAGYTG
SYCEDQVDECSPSPCQNGATCTDYPGGYSCECVAGYHGVNCSEEINECVSQPCQNGGTCI
DLTNTYKCSCPRGTQGVHCEVNVDDCSPPIDPVSRGPKCFNNGTCVDQVGGYSCTCPPGF
VGERCEGDVNECLSNPCDARGTQNCVQRVNDFYCECRAGHTGRRCESVINGCKGRPCQNG
GTCAVASNTARGFICKCPAGFEGATCENDARACGSRRCLNGGTCISGPRSPTCLCLGAFT
GPECQFPAGSPCVGGNPCYNQGSCEPTAESPFYRCLCPAKFNGLLCHILDYSFGGGLGLD
IPPPQIEEACELPECREEAGNKVCSLACNNHACGWDGGDCSLNFNDPWQNCSQSLQCWKY
FSNGRCDSQCNSVGCLFDGFDCQRVEGQCNPLYDQYCKDHFGDGHCDQGCNSAECEWDGL
DCAEHMPERLAAGALVLVVLTPPAQLRNNSLHFLRELSRLLHTNVVFKRDAHGQPMIFPY
YGHEEELRKHPIKRAADGWAAPGALLDRVEAALLPRGGAGRRRRELDPMDIRGSIVYLEI
DNRQCVQSSSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPPQLHFMYVA
VAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNA
SDGALMDDNQNEWGDEDLEAKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRVSAMAP
TPPQGEADADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASL
HNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQIL
IRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNN
VEAAIVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDI
AQERMHHDIVRLLDEYSLVRSPQLHGTALGGAPTLSPPLCSPNGYLGNLKPAVPGKKARK
PSTKGLACGGKEAKDLKARRKKSQDGKGCLLDSSSVLSPVDSLESPHGYLSDVASPPLLS
SPFQQSPSVPLGHLPGMPDAHLGVGHLSVAAKPEMAALGAGGRLAFEAGPPRLSHLPVAS
STSAVLGTAGAGGGGGAVNFTVGGAAGLNGQCEWLSRLQNGLVPNQYNPLRGNVASGPLS
TQAPALQHSMMGPLHGSLSTTAALSQMMSYQALPNTRLAGQPHLVQTQPLQQVQQQQQNL
QLQQPGLQTQQNLQPPNVQQPQSLPPQPHLSVSSAAGGHLGRSFLGGEPSQADVQPLGPS
GLAVHTILPQDSQALPTALPATLAPPMTTAQFLTPPSQHSYSSSPADNTPSHQLQVPEHP
FLTPSPESPDQWSSSSPHSHVSDWSEGISSPPTSTQSHIAHIPEALK
NT seq 7704 nt   +upstreamnt  +downstreamnt
atgccgccgctcctggcgcccctgctttgcctggcgctgctgcccgcgctcgccgcacga
ggcctgcgatgttcccagcccagtgagagctgcttgaatggcgggaagtgtgaagtgttc
cccaacggcaccgaagcctgtgtttgcagcggggcctttgtgggccagcgatgccaggcg
cccagcccctgtctcagcgccccctgcaagaacgccgggacatgccacgtggtggaccgc
ggaggcctggtggactacgcctgcacctgccgcctgggattttccgggcccctctgcctg
acgccccaagacaacgcctgcctctccaccccgtgtcgcaacgggggcacctgtgacctg
ctcacgctcaccgagtacaagtgccgctgccccccgggctggtcagggaagacgtgccag
caggccgacccgtgcgcctccaacccctgtgccaatggcggccagtgcctgccctttgag
gcctcgtacatctgtggctgcccacccggcttccacggccccacctgcaggcaggacgtg
aatgagtgcagccagaaccccaggctctgccagaacgggggcacctgccacaacgaggtc
ggctcctaccgctgcacctgccgcaccacccacactggcccccactgcgagctgccctac
gtgccctgcagcccctccccctgccagaatgggggcacctgccgccccacgggggacacc
acccacgagtgcgcctgtctgccaggcttcactggccagaactgtgaggagaacgtggac
gactgtccaagcaacaattgcaagaacggaggtgcttgtgtggacggcgtgaacacctac
aactgccgctgtcccccagagtggacaggtcagtactgcaccgaggacgtggacgagtgc
cagctcatgcccaacgcctgccagaacggcggcacgtgccacaacagccacggcggctac
aactgcgtgtgcgtcaacggctggacaggcgaggactgcagcgagaatatcgacgactgc
gccagtgccgcctgcttccacggcgccacctgccacgaccgcgtggcctccttctactgc
gagtgtccccatggccgcacgggcctgctgtgccacttgaacgacgcctgcatcagcaac
ccttgcaacgagggctccaactgcgacaccaaccctgtgaacggcaaagccatctgcact
tgcccctcggggtacacggggccggcctgcagccaggatgtggacgagtgctcgctgggt
gccaacccctgtgagcacgcgggcaagtgcatcaacacgctgggctcctttgagtgccag
tgtctacaaggctacaccggcccccgttgtgagatcgacgtcaacgagtgcatctcgaac
ccgtgtcagaatgatgccacctgcctggaccagatcggggagttccagtgcatctgcatg
cctggctacgagggcgtgcactgtgaggtcaacacggacgagtgtgccagtagcccctgt
ctccagaacggccgctgcctggacaaaatcaacgagtttctgtgcgagtgctccacaggc
ttcaccggacatctgtgtcagtatgacgtggacgagtgtgcaagcacgccctgcaagaac
ggcgccaagtgcttggacgggcccaacacctacacctgcgtgtgcacagaaggctacacg
gggccgcactgcgaggtggacatcgacgagtgtgaccctgatccgtgccactatggggtg
tgcaaggatggggtggccaccttcacctgcctgtgccggccgggctacacaggtcaccac
tgtgagagcaacatcaacgagtgccacagtcagccctgccggcatggcggcacctgccag
gaccgcgacaacgcctatctctgctcctgcctcaaggggaccacaggacccaactgtgag
acaaacctggacgactgcgtcagcagcccctgcgactcgggcacgtgcctggacaagatc
gacggctatgagtgtgcgtgcgagcccggctacacggggagcatgtgcaacgtgaacatc
gacgagtgcgcgggcaacccctgccaccacgggggtacctgtgaggatggtgtcaacagc
ttcacatgccgctgccccgagggctaccacggccccacgtgcctgtccgaggtcaacgag
tgtagcagtgacccctgcatccacggggcctgccgggacagcctcaacgggtacaagtgt
gactgtgaccctgggtggagtggggccaactgtgacgtgaacaacgatgagtgtgagtcc
aacccgtgtgcgaatggcggcgcctgccgagacatgaccagcggctacgtgtgcacctgc
cgcgagggcttcagtggccccaactgccaaaccaacatcaatgagtgtgcatccaaccca
tgcctgaaccagggctcgtgcatcgatgacgtggccgggtacaagtgcaactgtccactg
ccctacacaggagccacatgtgaggtggtgctggccccgtgcgcccctgggccctgcaga
aacgggggcgtgtgtaaagagtccgaggactatgagagtttctcctgcatctgccccacg
ggctggcaaggacagacctgcgaggtcgacattaacgagtgtgtaaagagcccgtgccgc
aatggtgcctcgtgccagaacaccaacggcggttaccgctgccgctgccgcgcgggctac
acggggcacaactgcgagacggacgtggacgactgctggccaaacccgtgccacaatggc
ggttcctgcactgatggcatcaacacagctttctgcgactgcctgcccggcttccgggga
gccttctgcgaggaggacatcaacgagtgtgccagcaacccgtgccgccacggcgccaac
tgcacagactgcgtggacagctacacgtgcacctgccccacgggcttcagcgggatccac
tgtgagaacaacacgcctgactgcacagagagctcttgctttaatggaggcacctgtgtg
gatggcatcaactccttcacctgcctgtgtccgccgggcttcacgggcagctactgtcag
catgacatcaacgagtgcgactcgcggccctgcctgcacggtggcacctgccaggacagc
tacgggacctacaagtgcacctgcccgcagggctacacgggcctcaactgccagagcctc
gtgcgctggtgcgactcctcgccctgcaagaacggtggcaggtgctggcagaccaacacg
cggtaccgctgcgagtgccacagtggctggaccggcctctactgcgacgtgcccaacgtg
tcctgtgaggtggccgcccagcggcaagacatcaacgtcacccacctgtgccggaacggg
ggcctctgcatggacgcaggcaatacccatcattgccgttgccaggcaggctacacgggc
agctactgcgaggaccaggtggacgagtgctcacccagcccctgccagaatggggccacc
tgcaccgactacccgggtggctactcctgtgagtgcgtggccgggtaccacggggtgaac
tgctccgaggagatcaacgagtgtgtgtcgcagccatgccagaacgggggcacctgcatc
gatctcaccaacacctacaagtgctcctgtccccggggcacacagggcgtgcactgtgag
gtcaacgtggacgactgcagtccccccatcgaccccgtctcccggggccccaagtgcttt
aacaacggcacctgcgtggaccaggtgggcggctacagctgcacctgtccacccggcttc
gtgggcgagcgctgtgagggcgatgtgaatgagtgcctgtccaacccctgtgacgcccgt
ggcacccagaactgcgtgcagcgtgtcaatgacttctactgcgagtgccgcgcaggccac
accggccgccgctgtgagtcggtcatcaacggctgcaaaggcaggccctgccagaacggg
ggcacctgcgccgtggcctccaacacagcccgcgggttcatctgcaagtgccccgcgggc
ttcgagggcgccacgtgtgagaacgatgcacgcgcctgtgggagccggcgctgcctcaat
ggcggcacgtgcatctcaggcccgcgcagccccacctgcctgtgcctgggcgccttcacc
ggccccgagtgccagttcccggccggcagcccctgcgtgggcgggaacccctgttacaac
cagggcagctgtgagcccaccgccgagagccccttctaccgctgcctgtgccctgccaag
ttcaacgggctcctgtgccacatcctggactacagcttcgggggcggcctgggcctcgac
atcccgccgccgcagatcgaggaggcgtgcgagctgcccgagtgccgcgaggaggcgggc
aacaaggtgtgcagcctggcctgcaacaaccatgcgtgcggctgggacggcggcgactgc
tcgctcaacttcaacgacccctggcagaactgctcacagtcactgcagtgctggaaatac
ttcagcaacggccgctgcgacagccagtgcaactctgtgggctgcctgttcgatggcttc
gactgccagcgcgtggagggccagtgcaaccccctgtacgaccagtactgcaaggaccac
tttggcgacgggcactgcgaccagggctgcaacagcgctgagtgcgagtgggacgggctg
gactgcgcggagcacatgcccgagcggctggcggccggcgcgctcgtgctggtggtgctg
accccgcccgcgcagctgcgcaacaactcactgcacttcctgcgggagctcagccgcctg
ctgcacaccaacgtggtgttcaagcgtgacgcccatggccagcccatgatcttcccgtac
tacggccacgaggaggagctgcgcaaacaccccatcaagcgcgcggccgacggctgggcc
gcgcctggggccctgctcgaccgagtggaggccgccctgctcccgcgcggcggggcgggc
cgccggcgcagggagctggaccccatggacatccgcggatctatcgtctacctggagatc
gacaaccggcagtgtgtccagtcttcctcacaatgcttccagagcgccacggacgtggcc
gccttcctgggcgcgctcgcctcactggggagcctcaacatcccctataagatcgaggcc
gtgcagagtgagaccgtggagccgcccccacccccgcagctgcacttcatgtacgtggcc
gtggccgccttcgtgctgctcttcttcgtgggctgtggggtgctgctgtcccggaagcgc
cggcggcagcatggacagctctggttccccgaaggcttcaaggtttcagaggccagcaag
aagaagcggcgggagcccctcggcgaggactccgtgggcctcaagcccctgaagaacgcc
tcagatggcgctctcatggacgacaaccagaatgagtggggggacgaggacctcgaggcc
aagaagttccggttcgaggagccagtggttcttcccgacctggacgaccagacggaccac
cggcaatggacgcagcagcacctggacgctgccgacctgcgtgtgtcggccatggccccc
acgccaccccagggcgaagccgacgccgactgcatggacgtcaatgtccgagggccagac
ggcttcacgcccctcatgatcgcctcctgcagcggagggggcctggagacgggcaacagc
gaggaggaggaagacgcgccggccgtcatctccgacttcatctaccagggagccagcctg
cacaaccagaccgaccgcactggcgagaccgccctgcacctggctgcccgctactcacgg
tctgacgcggccaagcgcctgctggaggccagtgcggacgccaacatccaggacaacatg
ggccgcaccccgctgcacgccgccgtgtctgccgacgcacagggagtcttccagatcctc
atccggaaccgggccacggacctggacgcccgtatgcacgacggcacgacgccgctgatc
ctagcggcccgcctggctgtcgagggcatgctggaagacctgatcaactcgcacgccgat
gtcaatgccgtggacgacttgggcaagtctgccctgcactgggccgccgccgtgaataac
gtggaggctgccatcgtgctcctgaagaacggggccaacaaagacatgcagaacaacaag
gaggagacacccctgttcctggctgctcgggagggcagctacgagacagccaaggtgctg
ctggaccacttcgccaaccgggacatcacagaccacatggaccgcctgcctcgcgacatc
gctcaggagcgtatgcaccacgacatcgtgcggctgctggatgagtacagcctggtgcgc
agcccccagctgcacggcactgccctgggcggcgcacctaccctgtccccgccgctctgc
tctcccaatggctacctgggcaacctcaagccggccgtgccgggcaagaaggcccgcaag
cccagcaccaagggcctggcctgtggcggcaaggaggccaaggacctcaaggcacgcagg
aagaaatcccaggacggcaagggctgcctgctggacagctcgagcgtgctgtcgcccgtg
gactcccttgagtcaccccacggctacctgtcggacgtggcctcgccgcccctcctgtct
tctccattccagcagtccccgtccgtgcccctcggccacttgcccggcatgcctgacgcc
cacctgggtgttggccacctgagtgtggctgccaagcccgagatggcagcgctgggtgcg
ggtggccggctggcctttgaggcaggaccaccgcggctctcccacctgcccgtggcctcc
agcaccagtgccgtcctgggcactgcgggtgccggcggcggcggcggggccgtgaatttc
accgtgggcggggccgcgggcttgaatggccagtgcgagtggctgtcccggctgcagaac
ggcctggtgccaaaccagtacaacccgctgcgagggaacgtggcgtcgggccccctgagc
acgcaggcccctgccctgcagcacagtatgatgggcccgctgcacggcagcctctccacc
acggccgccctgtcccagatgatgagctaccaggccctgcccaacacacgcctggccggc
cagccgcacctggtacagacccagccactgcaacaggtgcagcaacagcaacagaacttg
cagctgcagcagcccggcctgcagacgcagcaaaacctgcagccgcccaacgtccagcag
ccgcagagcctgccgccgcagccgcacctcagcgtgagctcggccgccggtggccacctg
ggccggagcttcctgggcggggagccgagccaggcggacgtgcagccgctgggccccagc
ggcctggcagtgcacaccatcctgccgcaggacagccaggccctgcccacggccctgccc
gccacgctggccccgcccatgaccactgctcagttcctgaccccgccctcgcagcacagc
tattcttcctcacctgcggacaacacccccagccaccagctgcaggtgcccgagcacccc
ttcctcaccccgtcgcccgagtccccggaccagtggtccagctcatcaccacattcccac
gtgtctgactggtctgagggcatctccagcccgcccaccagcacgcagtcccacatcgcc
cacattccagaggcgctcaagtaa

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