Eumetopias jubatus (Steller sea lion): 114205325
Help
Entry
114205325 CDS
T07240
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju00562
Inositol phosphate metabolism
eju01100
Metabolic pathways
eju04014
Ras signaling pathway
eju04015
Rap1 signaling pathway
eju04020
Calcium signaling pathway
eju04024
cAMP signaling pathway
eju04070
Phosphatidylinositol signaling system
eju04919
Thyroid hormone signaling pathway
eju04933
AGE-RAGE signaling pathway in diabetic complications
eju05205
Proteoglycans in cancer
Module
eju_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
114205325 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
114205325 (PLCE1)
04015 Rap1 signaling pathway
114205325 (PLCE1)
04020 Calcium signaling pathway
114205325 (PLCE1)
04070 Phosphatidylinositol signaling system
114205325 (PLCE1)
04024 cAMP signaling pathway
114205325 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
114205325 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
114205325 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
114205325 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
eju04131
]
114205325 (PLCE1)
Enzymes [BR:
eju01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
114205325 (PLCE1)
Membrane trafficking [BR:
eju04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
114205325 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
114205325 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
114205325
NCBI-ProteinID:
XP_027954522
LinkDB
All DBs
Position
Unknown
AA seq
2301 aa
AA seq
DB search
MTSEEMAASVLTPVTQRKVTSTPSAVDESSEKVSDVSVPRAHSVRQSGQTSTIPRMNKLK
EEPSGSNLPKILSIAREKIVSDENSNEKCWAESTPVSVKNLNINHNNILTNRQCILPQSQ
CYDTCNSVMEEDPCLETGIPSSLERKAFPGIQLEIDGPPMDISPLGSQSAAVETGQADPD
SNTAAFHFHYEVERRVSDAFCTLSGNLILDDCGNCVPLPGIGGEQKKNYVAYTCKLMELA
ENCDNKNGQLQCDHCDTLDDKYLCFEGSCQRASVVCSSDSFCREDLTNSPPAKTFLSHFE
DFPDNCEDVEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGLEAY
SYIDQKRSGLLLPSGRILERLSVVAIRQDGSRCLSEAQWYRIYNAVRRGEEIENTIGSLL
HVFTKLPASETAHERISVSPCLKQCVRDTLCEYRATLQRTSISQYITGSLLEATTSLGAR
SGLLSTFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILM
EQEQNIYRRVLPVDYLCFLTRDLGTPERQTSLPCLKASISASILTSQNGEHNALEDLVMR
FNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA
SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNGIFQIIRSCSRS
LEAEDDDSPSEGNSSRKNSLRDKARWQFIIGDLLDSENDIFEQSKEWDSHGSEEPQKAFD
HGTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTAS
PASAKAKLGVLSNTSEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQN
KLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSLGISAKSAEKPSVQRNNTLG
ISTTKKKKKTLIRGESGEAADDEMATRKTKMHRESRSRSGSDPQDMNEQEESEANAFMSP
PNTLPSRRAHSLTTAGSPNLSAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSGHGRIKGGM
KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCNRAGSESAPLYTNLTI
DENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLG
IFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNF
ASRNDESQENIKDLQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC
WDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEI
FKTVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLA
SMQAQAYNGGNANPPPASNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYN
EEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGL
STLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKASGKSSCEGMRQAWEESSSPLN
PTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPN
PLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLE
RDLDNMEPAIYSLTIVSGQNVCPSSGTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMW
NEQFLFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISS
LFINSRRMEENSSSSAVPASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQ
LLQQILTTEQDTKPIVTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSWFPE
EGYVGRIVLKTQQENLEERSIVQDDKEVILNSEEESFFVQVHDVSPEQPRTVIKAPRVST
AQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDATKKSSTPKSSQRVLLDQECVFQA
QSKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSPSQVLASENV
QTKEEKLVGSLPSSDTTEYRQ
NT seq
6906 nt
NT seq
+upstream
nt +downstream
nt
atgacgtctgaagaaatggcagcttctgttctcacacctgtgactcagagaaaagtgacg
tccactccatcggctgtagatgaaagtagtgaaaaggtctcggatgtcagtgttccaagg
gcacatagtgtcaggcagagcgggcagacttctaccatcccacggatgaacaagcttaaa
gaagaaccttctggaagcaacttgcccaagattctctccatagcaagggagaaaatagtg
agcgatgagaacagcaatgaaaagtgctgggcagaaagcacaccagtttctgtgaaaaac
cttaacattaaccacaacaacatactgacaaaccgccagtgcatccttcctcagagccag
tgttatgacacgtgcaattctgtcatggaggaagacccatgtttggaaactggaatccca
tcctcactggaaagaaaggcatttcctggaattcaactggaaatcgatggacctcccatg
gacattagtcccttaggaagtcagtcagccgctgtagagactggccaggcagaccctgac
agtaacacggcagcatttcactttcattatgaagttgagagaagagtgtcagatgctttc
tgtaccctgtcaggcaacttgattttggatgattgtggaaactgtgtaccactgcctggt
attggtggggagcaaaagaaaaattatgtggcatatacttgtaaactcatggaattggct
gaaaactgtgataataagaatgggcagctgcagtgtgatcattgtgacaccttggatgac
aaatacttgtgctttgaaggctcttgccaaagggccagtgtggtatgttcaagtgacagc
ttttgcagggaggacttgactaacagtccacctgccaagacctttctgagccattttgag
gacttccctgataattgtgaagatgtagaagaagatttttttaagagcaaaaaggagagg
tccactttgttagtgaggagattttgtaaaaatgacagggaagtaaagaaatctgtgtat
accgggacaagggcaatcatgagaactctgccttctggtcacattgggctggaagcttac
agttacatcgatcagaagagaagtggtctcttattgcccagtgggagaattctggaaagg
ctgtcagtggtggcgattaggcaggacgggagccggtgcctatcagaagcccagtggtat
cggatctacaatgcagtgagaaggggagaagaaatagaaaatacaattggatctcttctc
catgtcttcacaaagctcccagcctccgagacagcccatgaaaggataagcgttagtcca
tgcttaaagcagtgtgtccgagacaccctatgtgagtaccgtgccaccctgcagaggacg
tccatatctcaatacatcacgggttctctcctagaagcaaccacatctttgggggctaga
agtggcctactcagtacttttggaggatccactggacgaatgatgctaaaagaacgccag
ccaggcacttccatggccaattccagtgccctcccttcaagttcagctgggatcagcaag
gagctgattgacctgcagcccctcattcagttcccagaggaagttgccagcatcctgatg
gagcaggaacagaacatttaccgaagggtcttgccagttgactatctttgcttcttgacc
cgggacttgggcactccagaacgccaaacatccctgccctgcctcaaagcatccatctca
gcttcgattcttacctcccagaacggagagcacaatgccctggaagatctggtgatgaga
tttaatgaggtgagctcctgggtgacgtggctgatcctcacggcgggctccatggaggag
aagcgagaagtcttctcctatttggtgcacgtggccaaatgctgctggaacatgggcaac
tacaatgctgtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatgtgg
cagtttatggaccagtctgacctggagaccatgaggagcctgaaggacgccatggctcag
cacgaatcttcctgcgagtacaggaaggtggtcacgcgggccctgcacatacccggctgt
aaggtggttcccttctgtggggtgtttctgaaggagctctgtgaagtactggatggagcc
tctggcctcatgaagctttgcccgaggtacaattcccaagaagaaactctagagttcgta
gccgattacagtggacaagataatttcctacaacgagtgggacataatggcctaaagaat
tcagagaaggagtccaccgtcaacggcatctttcagatcatcaggagctgcagccgaagt
ctggaggccgaggacgacgacagtcccagtgaaggcaacagctctaggaaaaattcctta
agggataaagcacggtggcagtttataattggagatttgttggattccgaaaacgacatc
tttgagcagtcaaaagaatgggactctcatggatcagaagagccacagaaggcctttgac
cacgggacagagctgatcccatggtacgtgctgtccatccgagctgatgtgcaccagttc
ctgctgcagggggccactgtcatccactacgaccaggacacgcacctgtcagcccgctgc
ttcctccagcttcagcctgacaacagcaccttgacctggataaagcctaccactgcctcc
ccagccagtgctaaagcaaaacttggtgtgcttagtaatacctctgagcctggcaaattc
ccgttactgggcaatgctggattaagtggcctggcagagggggtcctggatctgttttca
gcaaaggctgtgtacatgggacaccctagcattgatatacacactgtgtgtgttcagaac
aaactgggtagcatgtttctctcagagactggcgtgacactgctctatgggctccagacc
acggacaatagattattgcactttgtggcacccaagcacacagctaagatgctcttcagt
ggattgctagaactcacaagggccgtgaggaagatgaggaagttccctgaccagagacag
cagtggctgcggaaacagtatgtcagcctctaccaggaggacggacggtatgaaggccca
actttggctcatgctgtggagctgtttggtggccggcgatggagtacacgcaatcccagc
cttgggatatccgcaaagagtgctgagaagcccagtgtgcagagaaacaacaccttgggc
ataagcaccaccaagaaaaagaagaaaacccttataaggggtgagagtggagaggcggct
gacgacgagatggccacgcggaagaccaaaatgcacagggagagtcgcagccggagtggt
tccgaccctcaagacatgaatgagcaagaagaatccgaggcaaatgccttcatgagccct
cctaacactctgccttccagaagagcccactctttgaccacagctgggtctcctaacttg
tctgccgggacatcatctcccatcaggccagtgtcctcccctgtgctgtcttcttcaaac
aagagcccgtccagtgcttggagcagcagtagcgggcacgggaggatcaaaggaggaatg
aagggttttcagagcttcatggtttcagacagtaacatgagttttgttgaattcgttgag
ctgttcaaatcattcagcgtgaggagccgcaaggacctgaaggatctctttgacatctac
gccgtgccctgcaaccgagccggctccgagtcggcccccctgtatacgaacctaacaatc
gacgaaaacaccagcgaccttcagcctgatctagatttactgaccagaaatgtctcggac
ttggggttgttcattaagagtaaacagcagctgtccgacaaccagaggcagatatctgat
gctattgctgctgcaagtatcgtgacaaatggcactggggtcgagagcacatctctgggc
atctttggggttggcatactccagctcaatgacttccttgtcaactgccagggagaacac
tgcacttatgatgaaatcctcagcatcatccagaagttcgagcctagcgttagtatgtgt
catcagggactactgtcatttgagggctttgcaaggtttctgatggataaagataatttt
gcctccagaaatgatgagtcacaggaaaacattaaagacttgcagctgcccctctcctac
tattacattgaatcttcacacaatacctacctcacaggccaccagctcaaaggagagtcc
tcagtggaactctacagtcaggtcctcctgcaaggctgcaggagcgtggagttggactgc
tgggatggagatgatgggatgcccatcatctaccacggacacacactgacaaccaagatc
cccttcaaggaggtggtagaagccatcgaccgcagtgccttcatcaactctgacctgccc
atcatcatatcaattgagaaccactgctcattgcctcagcaacgaaaaatggcagaaatt
ttcaagactgtgtttggagaaaaactggtggctaaattcctgtttgagagcgatttctca
gatgatccaatgcttccctcacctgaccaacttaggaggaaagtgcttcttaaaaataag
aagctaaaagcccaccagacaccagtggacatcctaaagcaaaaggctcatcagttagca
tccatgcaagctcaggcttataatggggggaatgccaaccccccacctgctagtaacgag
gaagaggaggatgaagaggatgaatacgattatgactatgaatccctgtctgatgacaac
attctagaagacagacctgaaaataaatcatgtaatgacaagcttcagttcgagtataat
gaagaaatccccaagaggataaagaaagccgataactctgcttgcaacaaaggaaaggtt
tatgacatggaactgggagaagaattttatcttcctcagaataaaaaggaaagcagacag
attgcaccagagctttctgaccttgtcatctattgccaagcggtaaaatttccaggcctg
tcaactctaaatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatt
tttggcaacaatccgggcagaatgagccctggggagacagcatcgtttaacaaagcatct
ggaaaaagttcctgtgaaggaatgcgacaggcctgggaggaatcttcttcccccctcaac
ccaaccacatccctcagcgctatcattagaactcccaaatgttaccatatctcatcgctg
aatgaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacacc
gcctgtcagctgctgaggacttacccggctgccacccgcatcgactcctccaaccccaat
cccctcatgttctggctccatgggatacagctcgtggcgctcaactaccagacagatgat
ctgcccttacatttaaatgctgccatgtttgaggccaacggtggctgtggttatgttcta
aaacccccagttctgtgggacaagaactgtcccatgtatcagaagttttcgcccttggaa
agagacctggacaacatggagcctgccatttattccttaactatcgtctctggtcaaaat
gtgtgtccgagcagcggcacggggagcccctgtatcgaagtcgacgtgctgggcatgccc
ctagacagctgccacttccgcacaaagcccatccaccggaacactctgaaccccatgtgg
aatgaacagtttctcttccgggttcactttgaagacctcatatttcttcgttttgctgtt
gtggaaaacaacagctcagccgtaaccgctcagagaatcatcccactcaaggctttaaaa
cgaggatatcggcatcttcagctacgaaacctccacaatgaagtcttggaaatctctagt
ttattcataaacagcagaaggatggaagaaaattcctccagcagtgccgtgccagcctct
ttgatgtttaatacagaagaaagaaaatgtttgcagactcacagagtcacagtgcatggg
gtcccgggtccagagccctttactgttttctccataaatggaggcaccaaggcaaagcag
cttctccaacaaattctgactactgaacaagacaccaaacctattgtcacagactatttt
ttgatggaagaaaaatattttatatctaaagaaaaaaatgaatgcaggaaacaaccattc
caaagagccatcggtccagaagaagagatcatgcagattttaagcagctggtttccagag
gaaggatatgttggcaggattgtcttaaaaacccagcaggaaaacctagaagagagaagc
attgttcaagatgacaaggaggtaatcttgaactccgaggaggagagtttctttgtccaa
gtgcatgacgtttctccagagcaacctcgaacagtcatcaaagcaccccgtgtcagcact
gcgcaggatgtcattcagcagaccttatgcaaagccaaatattcctatagcatcctgagc
aaccccaacccgagtgactacgtgcttttggaagaggtggtgaaagacgctaccaagaag
tcttccaccccgaagtcctcccagcgggttcttttggatcaggagtgtgtgtttcaagcc
caaagcaagtggaaaggtgcaggaaaattcatccttaagctaaaggagcaggtgcaggca
tcccgagaagacaaaagaaaaggcatttcttttgcaagtgaattcaagaagttcaccaag
tcaactaaacagccccgaggactcacatcaccttctcaggtcttggcctcagaaaatgtc
caaaccaaggaggagaaactggtgggcagcttgccctccagtgacaccacagagtaccga
caataa
DBGET
integrated database retrieval system
