Eumetopias jubatus (Steller sea lion): 114205555
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Entry
114205555 CDS
T07240
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
114205555 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
eju03032
]
114205555 (TOP2B)
03036 Chromosome and associated proteins [BR:
eju03036
]
114205555 (TOP2B)
Enzymes [BR:
eju01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
114205555 (TOP2B)
DNA replication proteins [BR:
eju03032
]
Eukaryotic type
DNA Topoisomerases
114205555 (TOP2B)
Chromosome and associated proteins [BR:
eju03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
114205555 (TOP2B)
Centrosome formation proteins
Centriole proteins
114205555 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
114205555
NCBI-ProteinID:
XP_027954863
LinkDB
All DBs
Position
Unknown
AA seq
1619 aa
AA seq
DB search
MAKAGGGAGAGGNGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHI
LLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMT
CIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRN
GYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDL
SKFKMDKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETG
VALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKK
KNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAAS
NCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGD
SAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYD
DAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKN
KQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGP
EDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKEL
ILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQA
LMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAVDD
NLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGL
DPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPM
LNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLF
DHMGCLKKYETVQDILKEFFDLRLSYYGLRREWLVGMLGAESTKLNNQARFILEKIQGKI
TIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPDFN
YILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQER
EDILAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKKKKGD
LDTTTVKVEFDEEFSGTPVEGTGEEALVPSAPVNKGPKPKRERKEPGTRVRKTPTSSGKS
SAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADD
DDDNNDLEELKVKASPITNDGEDEFIPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQDFG
NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTTA
KPKRAPKQKKVEPINSDSDSEFGIPKKTTPPKGKGRGAKKRKASGSENEGDYNPGRKTSK
TTSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4860 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggccggcggcggcgcgggagccggcggcaacggggcactgacctgggtgact
ctttttgatcagaacaatgctgcaaaaaaagaagagtcagaaactgcaaacaaaaatgat
tcttcaaagaagttgtctgttgagagagtgtatcagaaaaagacacaacttgaacatatt
ctccttcgtcctgatacatatattgggtcagtggaaccattgacacagctaatgtgggtg
tatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggtttatacaag
atctttgatgaaattttggttaatgcagctgacaataaacagagggataagaatatgacc
tgtattaaagtttctattgatcctgaatcaaatattataagcatttggaataatgggaaa
ggcattccagtagtagaacacaaagtagagaaagtttatgttccagcgttaatttttgga
cagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggtcgcaat
ggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaactgcttgc
aaagaatacaaacatagttttaagcagacatggatgaataacatgatgaagacttctgaa
gccaaaattaagcattttgatggtgaagattacacatgcataacattccaaccagatctg
tctaaatttaagatggataagcttgacaaggatattgtggccctcatgaccagaagagct
tatgatttggctggttcatgcaagggggtcaaggtcatgtttaatggaaagaaattgcct
gtaaatggatttcgcagttatgtagatctttatgtgaaagacaagttggatgaaactgga
gtggcactgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctcacactg
agtgaaaagggattccagcaaatcagctttgtaaatagtattgcaacaacaaaaggtgga
cgtcatgtggattatgtagtagatcaagttgttggtaaactgattgaagtagttaagaaa
aagaacaaagctggtgtatcagtaaaaccatttcaagtaaaaaaccatatatgggttttt
attaattgccttattgaaaatccaacttttgattctcagactaaggaaaacatgactctg
caacccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaagcagcttct
aactgtggcattgtagaaagtattctgaattgggtgaaatttaaggctcagactcagctg
aacaagaagtgttcatcagtaaagtatagtaaaatcaaaggtattcccaaactggatgat
gctaatgatgctggtggcaaacattccctggagtgtacactgatattgacagagggagac
tctgccaaatcgttggctgtgtctggattaggtgtgattgggcgagacagatatggagtc
tttccacttaggggaaaaattcttaacgtacgggaagcttctcataaacagatcatggaa
aatgcagaaataaacaatattatcaaaatagttggtctacagtacaagaaaagttatgat
gatgcagaatctctgaaaactttacgctatgggaagattatgattatgactgatcaggat
caagatggttctcacattaaaggcctgcttattaatttcatccatcacaattggccatca
cttttgaagcatggctttcttgaagagttcattactcctattgtgaaggctagcaaaaat
aagcaggaactttccttctatagtattcctgaatttgatgagtggaaaaaacatatagaa
aaccagaaagcctggaaaataaaatactacaaagggttgggtaccagtacagctaaagaa
gcaaaggaatattttgctgatatggaaaggcaccgcatcttgtttagatatgctggtcct
gaagacgatgctgccattaccttggcattcagtaaaaagaagattgatgacagaaaagaa
tggttaaccaattttatggaagaccgaagacagcgtaggttacatggcttaccagagcaa
tttttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaacaaggaattg
attctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggttttaaa
ccaggacaacgaaaagttttatttacctgtttcaagaggaatgataaacgtgaagtaaaa
gttgcccagttggctggatctgttgctgagatgtctgcttatcatcatggagaacaagca
ttgatgatgactattgtgaatttggctcagaactttgtgggaagcaacaacattaacttg
cttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgcaagccct
cgttatattttcacaatgttaagctctttatcaagactgctttttcctgctgtggatgac
aacctgctcaaattcctttatgatgataatcaacgcgttgagcctgagtggtatattcct
ataattcccatggttttaataaatggtgctgagggcattggtactggatgggcttgtaaa
ctacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggcttg
gatcctcatcctatgcttccgaattacaaaaactttaaaggaaccatccaagagcttggt
caaaaccagtatgcagtcagtggtgaaatatttgtggtggatagaaacacagtagagatt
acagagcttccagttagaacttggacacaggtatacaaagaacaggttttagaacctatg
ctaaatggaacagataaaacaccggcattaatttctgattataaagaatatcatactgat
acaactgtgaaatttgtggtgaaaatgactgaagagaagctagcacaagcagaagctgct
ggattgcacaaagtttttaaacttcaaactactcttacttgtaattccatggtactcttt
gatcatatgggatgtctcaagaagtatgaaaccgtgcaagacattttgaaagaattcttt
gatttacgattaagttattatggtttacgtagggagtggcttgtaggaatgttgggagca
gagtctacaaagcttaacaatcaagcccgtttcattttagagaagatacaaggaaaaatt
actatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaa
tctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaagaaaca
caaaaccagcatgatgatagttcctctgattcaggaactccttcaggccccgattttaat
tatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactgattaaa
cagagagatgcaaaagggcgagaagtcaatgatcttaaaagaaaatcaccttcagatctt
tggaaagaagacttagcagcatttgttgaagaactggataaagtggaagcgcaagaacga
gaggatattctggctggaatggctggaaaagcaataaaaggtaaagttggcaaacctaag
gtgaagaaacttcaattggaagagacaatgccctcaccttatgggagaagaatagttcct
gaaattactgctatgaaggcagatgccagcaaaaagttgctgaagaagaaaaagggtgat
cttgataccacaacagtaaaagtagaattcgatgaagaattcagtggaacaccagtagag
ggtactggagaagaggcattggtcccgtcagctcctgtaaataaaggtcccaaacccaaa
agggagagaaaggagcctggtaccagggtgagaaaaacacctacatcatctggtaaatcc
agtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtcagaaagt
gacttggaagaaacagaacctgtggttattccaagagattctttgcttaggagagcagct
gctgaaaggcctaagtacacatttgatttctcagaagaagaggatgatgatgctgatgat
gatgacgacaataatgatttagaggagctgaaagttaaagcatctcccataacaaatgat
ggggaagatgaatttattccttcagatggcctagataaagatgaatatacattttcacca
ggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaagtcaagattttggg
aatctcttctcatttccttcatactctcagaagtcagaagatgattcagctaaatttgac
agtaatgaagaagattctgcctctgttttttcaccatcgtttggtctgaaacaaacagat
aaggttccaagtaaaacagtagctgctaaaaagggaaaaccgtcttcagatacaactgct
aagcccaagagagctcctaaacagaagaaagtagagcctatcaactctgactcagattca
gaatttggcattccaaagaagactacacccccaaaaggtaaaggccgaggggcaaagaaa
aggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaacatccaaa
acaacaagcaagaaaccgaagaaaacatcttttgatcaggattcagatgtggacatcttc
ccatcagacttcacttctgaaccaccttctctgccacggaccggtagggctaggaaagaa
gtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatgtttaattaa
DBGET
integrated database retrieval system
