KEGG   Eumetopias jubatus (Steller sea lion): 114214730
Entry
114214730         CDS       T07240                                 
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X1
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
eju  Eumetopias jubatus (Steller sea lion)
Pathway
eju01521  EGFR tyrosine kinase inhibitor resistance
eju04012  ErbB signaling pathway
eju04062  Chemokine signaling pathway
eju04110  Cell cycle
eju04150  mTOR signaling pathway
eju04151  PI3K-Akt signaling pathway
eju04310  Wnt signaling pathway
eju04340  Hedgehog signaling pathway
eju04360  Axon guidance
eju04390  Hippo signaling pathway
eju04510  Focal adhesion
eju04550  Signaling pathways regulating pluripotency of stem cells
eju04657  IL-17 signaling pathway
eju04660  T cell receptor signaling pathway
eju04662  B cell receptor signaling pathway
eju04722  Neurotrophin signaling pathway
eju04728  Dopaminergic synapse
eju04910  Insulin signaling pathway
eju04916  Melanogenesis
eju04917  Prolactin signaling pathway
eju04919  Thyroid hormone signaling pathway
eju04931  Insulin resistance
eju04932  Non-alcoholic fatty liver disease
eju04934  Cushing syndrome
eju04935  Growth hormone synthesis, secretion and action
eju04936  Alcoholic liver disease
eju05010  Alzheimer disease
eju05020  Prion disease
eju05022  Pathways of neurodegeneration - multiple diseases
eju05135  Yersinia infection
eju05160  Hepatitis C
eju05162  Measles
eju05163  Human cytomegalovirus infection
eju05165  Human papillomavirus infection
eju05167  Kaposi sarcoma-associated herpesvirus infection
eju05200  Pathways in cancer
eju05210  Colorectal cancer
eju05213  Endometrial cancer
eju05215  Prostate cancer
eju05217  Basal cell carcinoma
eju05224  Breast cancer
eju05225  Hepatocellular carcinoma
eju05226  Gastric cancer
eju05415  Diabetic cardiomyopathy
eju05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eju00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    114214730 (GSK3B)
   04310 Wnt signaling pathway
    114214730 (GSK3B)
   04340 Hedgehog signaling pathway
    114214730 (GSK3B)
   04390 Hippo signaling pathway
    114214730 (GSK3B)
   04151 PI3K-Akt signaling pathway
    114214730 (GSK3B)
   04150 mTOR signaling pathway
    114214730 (GSK3B)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    114214730 (GSK3B)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114214730 (GSK3B)
   04550 Signaling pathways regulating pluripotency of stem cells
    114214730 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    114214730 (GSK3B)
   04657 IL-17 signaling pathway
    114214730 (GSK3B)
   04662 B cell receptor signaling pathway
    114214730 (GSK3B)
   04062 Chemokine signaling pathway
    114214730 (GSK3B)
  09152 Endocrine system
   04910 Insulin signaling pathway
    114214730 (GSK3B)
   04917 Prolactin signaling pathway
    114214730 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    114214730 (GSK3B)
   04919 Thyroid hormone signaling pathway
    114214730 (GSK3B)
   04916 Melanogenesis
    114214730 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    114214730 (GSK3B)
   04722 Neurotrophin signaling pathway
    114214730 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    114214730 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114214730 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    114214730 (GSK3B)
   05225 Hepatocellular carcinoma
    114214730 (GSK3B)
   05226 Gastric cancer
    114214730 (GSK3B)
   05217 Basal cell carcinoma
    114214730 (GSK3B)
   05215 Prostate cancer
    114214730 (GSK3B)
   05213 Endometrial cancer
    114214730 (GSK3B)
   05224 Breast cancer
    114214730 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    114214730 (GSK3B)
   05162 Measles
    114214730 (GSK3B)
   05163 Human cytomegalovirus infection
    114214730 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114214730 (GSK3B)
   05165 Human papillomavirus infection
    114214730 (GSK3B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    114214730 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    114214730 (GSK3B)
   05020 Prion disease
    114214730 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    114214730 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114214730 (GSK3B)
   05415 Diabetic cardiomyopathy
    114214730 (GSK3B)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    114214730 (GSK3B)
   04932 Non-alcoholic fatty liver disease
    114214730 (GSK3B)
   04931 Insulin resistance
    114214730 (GSK3B)
   04934 Cushing syndrome
    114214730 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    114214730 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:eju01001]
    114214730 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:eju03036]
    114214730 (GSK3B)
Enzymes [BR:eju01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     114214730 (GSK3B)
Protein kinases [BR:eju01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   114214730 (GSK3B)
Chromosome and associated proteins [BR:eju03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    114214730 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 114214730
NCBI-ProteinID: XP_027966346
LinkDB
Position
Unknown
AA seq 433 aa
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANAGDRGQ
TNNAASASASNST
NT seq 1302 nt   +upstreamnt  +downstreamnt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccagtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaggatggcagcaaggtgactacagtg
gtggcaactcctgggcagggtccagataggccacaagaagtcagctatacagacactaaa
gtgattggaaatgggtcatttggtgtggtatatcaagccaaactttgtgattcaggagaa
ctggttgccattaagaaggtattgcaggacaagagatttaagaaccgagagctccaaatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactcaagtggt
gagaagaaagatgaagtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgcttcctgtgatctatgtcaagttg
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatatgccatcgg
gatattaaaccacagaacctcttgttggatcctgatacagctgtcttaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagatgta
tggtctgcaggctgtgtgttggctgagctgttgctaggacaaccaatatttccaggggac
agtggtgtggatcagttggtggaaataatcaaggtcctggggacaccaacaagggagcaa
attagagaaatgaacccaaactacacagaattcaaattccctcaaattaaggcacaccct
tggactaaggattcgtcaggaacaggacatttcacctcaggagtgcgggtcttccgaccc
cggactccaccggaagcaattgcactgtgtagccgtctgctggagtatacaccaactgcc
cgattgacaccactggaagcttgtgcacattcattttttgatgaattaagggacccaaat
gtcaaattaccaaatgggcgagacacacctgcactcttcaacttcaccactcaagaactg
tcaagtaatccacctctagctaccatccttattcctcctcatgctcggattcaagcagct
gcttcaacccctacaaatgccacagcagcctcagatgctaatgccggagaccgtggacag
accaacaacgccgcttctgcatcagcttccaactccacctga

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